4 found
  1.  31
    Tailoring Consent to Context: Designing an Appropriate Consent Process for a Biomedical Study in a Low Income Setting.Fasil Tekola, Susan J. Bull, Bobbie Farsides, Melanie J. Newport, Adebowale Adeyemo, Charles N. Rotimi & Gail Davey - unknown
    Background Currently there is increasing recognition of the need for research in developing countries where disease burden is high. Understanding the role of local factors is important for undertaking ethical research in developing countries. We explored factors relating to information and communication during the process of informed consent, and the approach that should be followed for gaining consent. The study was conducted prior to a family-based genetic study among people with podoconiosis (non-filarial elephantiasis) in southern Ethiopia. Methodology/Principal Findings We adapted (...)
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  2.  63
    Voluntary Participation and Comprehension of Informed Consent in a Genetic Epidemiological Study of Breast Cancer in Nigeria.Patricia A. Marshall, Clement A. Adebamowo, Adebowale A. Adeyemo, Temidayo O. Ogundiran, Teri Strenski, Jie Zhou & Charles N. Rotimi - 2014 - BMC Medical Ethics 15 (1):38.
    Studies on informed consent to medical research conducted in low or middle-income settings have increased, including empirical investigations of consent to genetic research. We investigated voluntary participation and comprehension of informed consent among women involved in a genetic epidemiological study on breast cancer in an urban setting of Nigeria comparing women in the case and control groups.
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  3.  71
    Impact of Social Stigma on the Process of Obtaining Informed Consent for Genetic Research on Podoconiosis: A Qualitative Study.Fasil Tekola, Susan Bull, Bobbie Farsides, Melanie J. Newport, Adebowale Adeyemo, Charles N. Rotimi & Gail Davey - 2009 - BMC Medical Ethics 10 (1):13-.
    BackgroundThe consent process for a genetic study is challenging when the research is conducted in a group stigmatized because of beliefs that the disease is familial. Podoconiosis, also known as 'mossy foot', is an example of such a disease. It is a condition resulting in swelling of the lower legs among people exposed to red clay soil. It is a very stigmatizing problem in endemic areas of Ethiopia because of the widely held opinion that the disease runs in families and (...)
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    Genetic Ancestry Tracing and the African Identity: A Double-Edged Sword?Charles N. Rotimi - 2003 - Developing World Bioethics 3 (2):151–158.
    ABSTRACTAs both a geneticist and a Nigerian living in the United States, the author responds to the prospect of African Americans using genetic science to trace their ancestry to the African continent. He articulates concerns about both the limitations of the science to offer satisfying, accurate, and meaningful results, and the ability of individuals to make real, life‐altering sense of these results. However, he notes that given the history and impact of slavery on African Americans, the desire to trace roots (...)
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