Purpose: This study explores social networkers' interest in and attitudes toward personal genome testing (PGT), focusing on expectations related to the clinical integration of PGT results. Methods: An online survey of 1,087 social networking users was conducted to assess 1) use and interest in PGT; 2) attitudes toward PGT companies and test results; and 3) expectations for the clinical integration of PGT. Descriptive statistics were calculated to summarize respondents' characteristics and responses. Results: Six percent of respondents have used PGT, 64% (...) would consider using PGT, and 30% would not use PGT. Of those who would consider using PGT, 74% report they would use it to gain knowledge about disease in their family. 34% of all respondents consider the information obtained from PGT to be a medical diagnosis. 78% of those who would consider PGT would ask their physician for help interpreting test results, and 61% of all respondents believe physicians have a professional obligation to help individuals interpret PGT results. Conclusion: Respondents express interest in using PGT services, primarily for purposes related to their medical care and expect physicians to help interpret PGT results. Physicians should therefore be prepared for patient demands for information and counsel on the basis of PGT results. (shrink)
Ha sido mi interés en los últimos años reflexionar formalmente sobre la conciencia en referencia a sus fundamentos y aspectos biológicos, en especial los cerebrales y los de comportamiento. Urdiendo sobre sus aspectos fisiológicos, fenomenológicos, epistemológicos y ontológicos, he explorado la naturaleza del dolor como un estado paradigmático de conciencia en un cuento de “neurociencia ficción” (Díaz, 2002), en un trabajo publicado en Salud Mental (Díaz, 2007) y en un libro sobre la conciencia viviente (Díaz, 2007). Estos análisis utilizan al (...) dolor como un fenómeno de conciencia fértil para examinar las principales conjeturas vigentes sobre la relación mente cuerpo y el problema epistemológico del acceso científico a la conciencia. La presente comunicación es un breve repaso de las principales ideas exploradas que se especifican en un decálogo de afirmaciones sobre la naturaleza y el conocimiento del dolor. Medical Epistemology: Ten Postulates on Pain It has been my interest in recent years to formally reflect on consciousness’s biological aspects and foundations, especially the brain-related and behavioral ones. In dwelling on its physiological, phenomenological, epistemological and ontological aspects, I have explored the nature of pain as a paradigmatic state of consciousness in a “neuroscience-fiction” tale (Díaz, 2002), in a work published in Mental Health (Díaz, 2007), and in a book on living consciousness (Díaz, 2007). These analyses use pain as a fertile consciousness phenomenon in order to examine the main current conjectures on the mind-body relation and the epistemological problem of scientific access to consciousness. This work is a brief summary of the main ideas explored, specified as a Decalogue of statements on the nature and knowledge of pain. (shrink)
¿Existe una incompatibilidad estructural entre fe religiosa y logos filosófico? Así parecen darlo por supuesto diversas orientaciones filosóficas de la modernidad. Sin embargo, el cristianismo ha convivido desde siempre con la filosofía, la ha acogido y cultivado. Carlos Díaz presenta en este breve trabajo la sintonía profunda que se da en la concreción real del ser humano entre el logos filosófico y el propio de la experiencia religiosa.
There has been relatively little empirical research into the causes of research misconduct. To begin to address this void, the authors collected data from closed case files of the Office of Research Integrity (ORI). These data were in the form of statements extracted from ORI file documents including transcripts, investigative reports, witness statements, and correspondence. Researchers assigned these statements to 44 different concepts. These concepts were then analyzed using multidimensional scaling and cluster analysis. The authors chose a solution consisting of (...) seven clusters: (1) personal and professional stressors, (2) organizational climate, (3) job insecurities, (4) rationalizations A, (5) personal inhibitions, (6) rationalizations B and, (7) personality factors. The authors discuss the implications of their findings for policy and for future research. (shrink)
The syllogism and the predicate calculus cannot account for an ontological argument in Descartes' Fifth Meditation and related texts. Descartes' notion of god relies on the analytic-synthetic distinction, which Descartes had identified before Leibniz and Kant did. I describe how the syllogism and the predicate calculus cannot explain Descartes' ontological argument; then I apply the analytic-synthetic distinction to Descartes’ idea of god.
Subtractive schooling is a type of pedagogy that subtracts from the student aspects of her identity in order to assimilate and reshape her identity to fit the American mainstream. Here, I question the value of assimilation as it takes place in our public school systems. Currently, immigrant children are often made to feel inadequate for being culturally different. This is detrimental to their development as students given that at their young age they do not yet have the emotional maturity to (...) know that their experience, language and culture are legitimate and valuable. My goal is to shift the focus of subtractive schooling to one that fosters the growth of students through recognition. I suggest that John Dewey’s and Paulo Freire’s pedagogy of recognition is a helpful approach to this problem. Both Dewey and Freire’s pedagogy emphasize recognition as central to their pedagogy. (shrink)
The current ethical structure for collaborative international health research stems largely from developed countries' standards of proper ethical practices. The result is that ethical committees in developing countries are required to adhere to standards that might impose practices that conflict with local culture and unintended interpretations of ethics, treatments, and research. This paper presents a case example of a joint international research project that successfully established inclusive ethical review processes as well as other groundwork and components necessary for the conduct (...) of human behavior research and research capacity building in the host country. (shrink)
Abstract The architecture of brain, consciousness, and behavioral processes is shown to be formally similar in that all three may be conceived and depicted as Petri net patterned processes structured by a series of elements occurring or becoming active in stochastic succession, in parallel, with different rhythms of temporal iteration, and with a distinct qualitative manifestation in the spatiotemporal domain. A patterned process theory is derived from the isomorphic features of the models and contrasted with connectionist, dynamic system notions. This (...) empirically derived formulation is considered to be optimally compatible with the dual aspect theory in that the foundation of the diverse aspects would be a highly structured and dynamic process, the psychophysical neutral ?ground? of mind and matter posed (but not properly determined) by dual aspect and neutral monist theories. It is methodologically sound to approach each one of these processes with specific tools and to establish concurrences in real time between them at the organismic level of analysis. Such intra?level and inter?perspective correlations could eventually constitute psychophysical bridge?laws. A mature psychology of consciousness is necessary to situate and verify the bridges required by a genuine mind?body science. (shrink)
Oaksford and Chater (1994) proposed to analyse the Wason selection task as an inductive instead of a deductive task. Applying Bayesian statistics, they concluded that the cards that participants tend to select are those with the highest expected information gain. Therefore, their choices seem rational from the perspective of optimal data selection. We tested a central prediction from the theory in three experiments: card selection frequencies should be sensitive to the subjective probability of occurrence for individual cards. In Experiment 1, (...) expected frequencies of the p- and the q-card were manipulated independently by concepts referring to large vs. small sets. Although the manipulation had an effect on card selection frequencies, there was only a weak correlation between the predicted and the observed patterns. In the second experiment, relative frequencies of individual cards were manipulated more directly by explicit frequency information. In addition, participants estimated probabilities for the four logical cases and of the conditional statement itself. The experimental manipulations strongly affected the probability estimates, but were completely unrelated to card selections. This result was replicated in a third experiment. We conclude that our data provide little support for optimal data selection theory. (shrink)
Resumen: A la luz de la distinción elaborada por E. Tugendhat entre religión y mística, retomada a su modo por el teólogo J. Ratzinger, se examina la idea hegeliana según la cual la filosofía eleva la forma representativa propia de la religión a concepto. ¿Significa esto que la religión cristiana es..
En Guedi, un oasis en la orilla occidental del Mar Muerto, es uno de los más importantes yacimientos del desierto de Judea. En el periodo romano—bizantino En Guedi fue famosa par sus excelentes dátiles y por sus plantaciones de bálsamo. En la última fase de su sinagoga hay una extraña inscripción, cuya interpretación ha ocupado el interés de muchos estudiosos. El presente artículo es un intento de aproximación al correcto significado de la inscripción de En Guedi con inclusión de los (...) últimos datos conocidos. (shrink)
Scientific-technological innovation (particularly in the field of transgenic foods and cloning), scientific journalism and public opinion all share a complex relationship. The rupture of internal consensus among the scientific community, the role played by scientific journalists as "mediators" and the differentiation between what can be referred to as the "informed public" or "epistemological leaders" and the rest of the population were the starting point for our research on the impact of news related to biotechnological advances. In this paper we will (...) show the principal characteristics of the discourse on this type of news among what we can call the "informed public". From there, we will establish a set of strategies for improving the level of scientific-technological alphabetisation in our complex societies. (shrink)
It is usually supposed that the Dirac and radiation equations predict that the phase of a fermion will rotate through half the angle through which the fermion is rotated, which means, via the measured dynamical and geometrical phase factors, that the fermion must have a half-integral spin. We demonstrate that this is not the case and that the identical relativistic quantum mechanics can also be derived with the phase of the fermion rotating through the same angle as does the fermion (...) itself. Under spatial rotation and Lorentz transformation the bispinor transforms as a four-vector like the potential and Dirac current. Previous attempts to provide this form of transformational behavior have foundered because a satisfactory current could not be derived.(14). (shrink)
Background Non-therapeutic trials in which terminally ill cancer patients are asked to undergo procedures such as biopsies or venipunctures for research purposes, have become increasingly important to learn more about how cancer cells work and to realize the full potential of clinical research. Considering that implementing non-therapeutic studies is not likely to result in direct benefits for the patient, some authors are concerned that involving patients in such research may be exploitive of vulnerable patients and should not occur at all, (...) or should be greatly restricted, while some proponents doubt whether such restrictions are appropriate. Our objective was to explore clinician-researcher attitudes and concerns when recruiting patients who are in advanced stages of cancer into non-therapeutic research. Methods We conducted a qualitative exploratory study by carrying out open-ended interviews with health professionals, including physicians, research nurses, and study coordinators. Interviews were audio-recorded and transcribed. Analysis was carried out using grounded theory. Results The analysis of the interviews unveiled three prominent themes: 1) ethical considerations; 2) patient-centered issues; 3) health professional issues. Respondents identified ethical issues surrounding autonomy, respect for persons, beneficence, non-maleficence, discrimination, and confidentiality; bringing to light that patients contribute to science because of a sense of altruism and that they want reassurance before consenting. Several patient-centered and health professional issues are having an impact on the recruitment of patients for non-therapeutic research. Facilitators were most commonly associated with patient-centered issues enhancing communication, whereas barriers in non-therapeutic research were most often professionally based, including the doctor-patient relationship, time constraints, and a lack of education and training in research. Conclusions This paper aims to contribute to debates on the overall challenges of recruiting patients to non-therapeutic research. This exploratory study identified general awareness of key ethical issues, as well as key facilitators and barriers to the recruitment of patients to non-therapeutic studies. Due to the important role played by clinicians and clinician-researchers in the recruitment of patients, it is essential to facilitate a greater understanding of the challenges faced; to promote effective communication; and to encourage educational research training programs. (shrink)
We complete our previous(1, 2) demonstration that there is a family of new solutions to the photon and Dirac equations using spatial and temporal circles and four-vector behaviour of the Dirac bispinor. We analyse one solution for a bound state, which is equivalent to the attractive two-body interaction between a charged point particle and a second, which remains at rest. We show this yields energy and angular momentum eigenvalues that are identical to those found by the usual method of solving (...) of the Dirac equation,(4) including fine structure. We complete our previous derivation(2) of QED from a set of rules for the two-body interaction and generalise these. We show that QED may be decomposed into a two-body interaction at every point in spacetime. (shrink)
Dual aspect theory has conceptual advantages over alternative mind-body notions, but difficulties of its own. The nature of the underlying psychophysical ground, for one, remains problematic either in terms of the principle of complementarity or if mind and matter are taken to be aspects of something like energy, movement, or information. Moreover, for a dual aspect theory to be plausible it should avoid the four perils of all mind-body theories: epiphenomenalism, reductionism, gross panpsychism, and the problems of emergence. An alternative (...) dual aspect theory, patterned process theory, is introduced and defended in neurological and individuality terms. The concept is grounded in a brain model of hierarchies wherein consciousness is conceived to be a cognitive aspect of the highest emergent brain inter-module activity, which is situated in the context of a living organism coping with a changing environment. The notion of individuals as psychophysical units unfolding as patterned processes is shown to constitute an integrative approach to brain, consciousness, and behavior that can avoid the conceptual perils and meet the ontological requirements of dual aspect reality and thereby advance the foundations of an integrative mind-body science. (shrink)
Burning fossil fuel in the North American continent contributes more to the CO2 global warming problem than in any other continent. The resulting climate changes are expected to alter food production. The overall changes in temperature, moisture, carbon dioxide, insect pests, plant pathogens, and weeds associated with global warming are projected to reduce food production in North America. However, in Africa, the projected slight rise in rainfall is encouraging, especially since Africa already suffers from severe shortages of rainfall. For all (...) regions, a reduction in fossil fuel burning is vital. Adoption of sound ecological resource management, especially soil and water conservation and the prevention of deforestation, is important. Together, these steps will benefit agriculture, the environment, farmers, and society as a whole. (shrink)
Botanical preparations used by shamans in rituals for divination, prophecy, and ecstasy contain widely different psychoactive compounds, which are incorrectly classified under a single denomination such as “hallucinogens,” “psychedelics,” or “entheogens.” Based on extensive ethnopharmacological search, I proposed a psychopharmacological classification of magic plants in 1979. This paper re-evaluates this taxonomy in the context of consciousness research. Several groups of psychodysleptic magic plants are proposed: (1) hallucinogens—psilocybin mushrooms, mescaline cacti, dimethyltryptamine snuffs, and the synthetic ergoline lysergic acid diethylamide induce strong (...) perceptual changes, affective intensification, and cognitive enhancement. Their ethnobotanical uses include long lasting divination rituals, prophecy, and sacramental practice. (2) Trance-inducers—ergoline Convolvulaceae and South American Banisteriopsis produce quietness, abstraction, lethargy, mild sensorial and cognitive changes, and salient visual imagery changes used in trance rituals and specific divination practices. (3) Cognodysleptics—marijuana (tetrahydrocannabinol) and other terpene-containing plants induce changes in thought, imagination, and affective functions and are used in short-term divination or oneiromancy. (4) Deliriants—tropane-containing Solanaceae, wild tobacco, and Amanita muscaria (muscimol) induce a delirium characterized by dim and clouded consciousness, stupor, confusion, disorientation, perception distortion, difficulties in recollection, anxiety, irritability, excitation, and behavioral disorganization employed in sorcery, purification, or exorcism rituals. The core mental effects required for a drug to be used in shamanistic rituals include light-headedness, enhanced imagery, and experience intensification. This constellation was the reason why, in his classification of psychoactive compounds, the pioneer German psychopharmacologist Louis Lewin established in 1924 a group of drugs under the appropriate name of Phantastica. (shrink)
En este artículo se discute acerca de la existencia y la consistencia de un concepto de naturaleza humana en la obra de Nietzsche que no recaería en los extremos de las lecturas biologicistas ni historicistas de la misma. Para ello se lleva a cabo una interpretación que aúna la consideración nietzscheana de la naturaleza y de la historia alrededor del concepto-matriz de lo ahistórico, lo que conducirá la reflexión inicial sobre la cultura a un análisis en términos ontológico-formales de la (...) naturaleza del hombre y de su anclaje en la del mundo. (shrink)
Drawing on the work of John Rawls and Thomas Pogge, I argue that the U.S. is in part responsible for the immigration of Mexicans and Central Americans into the U.S. By seeking to further its national interests through its foreign policies, the U.S. has created economic and politically oppressive conditions that Mexican and Central American people seek to escape. The significance of this project is to highlight the role of the U.S. in illegal immigration so that we may first acknowledge (...) our responsibility in order to seek lasting humane solutions. (shrink)
E l auto r de f iend e un a democraci a a r mónica , qu e n o e s u n model o nu ev o d e democracia sin o l a relació n equilibrad a d e la s do s modalidade s clásica s d e democracia , l a representat iv a y l a directa , a la s qu e s e añadirí a l a democraci a pa r ticipat iv (...) a prom o vid a po r lo s ciudadanos, ind i vidualment e o e n gr upo , a l ma r ge n d e lo s pa r tido s políticos . L a resultant e serí a un nu evo marc o polític o co n meno s democraci a representat iva (l a d e lo s pa r tido s político s y lo s representante s electos) , q u e actualment e e s l a democraci a e xclus iva y e xclu y ent e en la s sociedade s política s a v anzadas , má s democraci a direct a (l a d e lo s ciudadano s qu e sin inte r mediario s v otaría n política s y n o sól o a su s representantes ) y u n nu evo espaci o polític o ocupad o po r lo s ciudadanos-actore s político s si n militanci a pa r tidista . E n cad a uno d e esto s tre s modelo s democrático s s e analiz a l a de f inició n de l modelo , e l escenari o que actualment e atr a vies a y la s propuesta s concreta s d e cambio. (shrink)
El tratamiento dispensado al hecho religioso en nuestro país y en general en las sociedades avanzadas es discriminatorio respecto a otros colectivos y grupos sociales. Discriminatorio en una dimensión interna y externa. Internamente, porque no todos los grupos religiosos reciben el mismo trato jurídico. Externamente, porque otros grupos sociales distintos a los religiosos, que buscan otros fines, no reciben el mismo trato que los grupos religiosos, sino más desfavorable. Junto a una primera discriminación en el ámbito extraeclesial -el de las (...) confesiones religiosas en su relación con las demás asociaciones del país-, hay otros dos supuestos en el ámbito intraeclesial -el de las relaciones de los grupos religiosos entre sí-, el contraste de las opciones fideístas y las no fideístas críticas y el de las confesiones religiosas mayoritarias y minoritarias. En uno y otro caso, interna y externamente, el hecho religioso se convierte en un criterio de discriminación, sin que en mi opinión existan razones objetivas suficientes. (shrink)