Results for 'Clyde Hutchison'

440 found
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  1.  96
    Complete Chemical Synthesis, Assembly, and Cloning of a Mycoplasma Genitalium Genome.Daniel Gibson, Benders G., A. Gwynedd, Cynthia Andrews-Pfannkoch, Evgeniya Denisova, Baden-Tillson A., Zaveri Holly, Stockwell Jayshree, B. Timothy, Anushka Brownley, David Thomas, Algire W., A. Mikkel, Chuck Merryman, Lei Young, Vladimir Noskov, Glass N., I. John, J. Craig Venter, Clyde Hutchison, Smith A. & O. Hamilton - 2008 - Science 319 (5867):1215--1220.
    We have synthesized a 582,970-base pair Mycoplasma genitalium genome. This synthetic genome, named M. genitalium JCVI-1.0, contains all the genes of wild-type M. genitalium G37 except MG408, which was disrupted by an antibiotic marker to block pathogenicity and to allow for selection. To identify the genome as synthetic, we inserted "watermarks" at intergenic sites known to tolerate transposon insertions. Overlapping "cassettes" of 5 to 7 kilobases (kb), assembled from chemically synthesized oligonucleotides, were joined by in vitro recombination to produce intermediate (...)
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  2.  5
    John A. Hutchison, 1912-2000.Julia K. Hutchison - 2000 - Proceedings and Addresses of the American Philosophical Association 74 (2):111 - 112.
  3.  15
    A Formative Decade: Methodological Controversy in the 1930s.T. W. Hutchison - 2009 - Journal of Economic Methodology 16 (3):297-314.
    An edited version of a semi-autobiographical piece that Terence Hutchison wrote in 2001?2003, shortly before his death, in which he reflected on the methodological developments in which he had been involved, centred on the London School of Economics, in the 1930s. It explains very clearly the context out of which his own work arose. Particular attention is paid to the work of Lionel Robbins, Frank Knight and the philosopher Felix Kaufmann.
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  4.  12
    Details Matter—Definitions and Context Can’T Be Glossed Over When Managing Innovation.Jane Johnson, Katrina Hutchison & Wendy A. Rogers - 2019 - American Journal of Bioethics 19 (6):28-29.
    Volume 19, Issue 6, June 2019, Page 28-29.
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  5. Women in Philosophy: What Needs to Change?Katrina Hutchison & Fiona Jenkins (eds.) - 2013 - Oxford University Press USA.
    Despite its place in the humanities, the career prospects and numbers of women in philosophy much more closely resemble those found in the sciences and engineering. This book collects a series of critical essays by female philosophers pursuing the question of why philosophy continues to be inhospitable to women and what can be done to change it. By examining the social and institutional conditions of contemporary academic philosophy in the Anglophone world as well as its methods, culture, and characteristic commitments, (...)
     
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  6.  2
    The Role of REM Sleep Theta Activity in Emotional Memory.Isabel C. Hutchison & Shailendra Rathore - 2015 - Frontiers in Psychology 6.
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  7. Is Classical Mechanics Really Time-Reversible and Deterministic?Keith Hutchison - 1993 - British Journal for the Philosophy of Science 44 (2):307-323.
  8.  29
    Challenging the Epistemological Foundations of EBM: What Kind of Knowledge Does Clinical Practice Require?Katrina J. Hutchison & Wendy A. Rogers - 2012 - Journal of Evaluation in Clinical Practice 18 (5):984-991.
    This paper raises questions about the epistemological foundations of evidence-based medicine . We argue that EBM is based upon reliabilist epistemological assumptions, and that this is appropriate - we should focus on identifying the most reliable processes for generating and collecting medical knowledge. However, we note that this should not be reduced to narrow questions about which research methodologies are the best for gathering evidence. Reliable processes for generating medical evidence might lie outside of formal research methods. We also question (...)
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  9.  3
    Device Representatives in Hospitals: Are Commercial Imperatives Driving Clinical Decision-Making?Quinn Grundy, Katrina Hutchison, Jane Johnson, Brette Blakely, Robyn Clay-Wlliams, Bernadette Richards & Wendy A. Rogers - 2018 - Journal of Medical Ethics 44 (9):589-592.
    Despite concerns about the relationships between health professionals and the medical device industry, the issue has received relatively little attention. Prevalence data are lacking; however, qualitative and survey research suggest device industry representatives, who are commonly present in clinical settings, play a key role in these relationships. Representatives, who are technical product specialists and not necessarily medically trained, may attend surgeries on a daily basis and be available to health professionals 24 hours a day, 7 days a week, to provide (...)
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  10.  17
    Evidence for Personalised Medicine: Mechanisms, Correlation, and New Kinds of Black Box.Mary Jean Walker, Justin Bourke & Katrina Hutchison - 2019 - Theoretical Medicine and Bioethics 40 (2):103-121.
    Personalised medicine has been discussed as a medical paradigm shift that will improve health while reducing inefficiency and waste. At the same time, it raises new practical, regulatory, and ethical challenges. In this paper, we examine PM strategies epistemologically in order to develop capacities to address these challenges, focusing on a recently proposed strategy for developing patient-specific models from induced pluripotent stem cells so as to make individualised treatment predictions. We compare this strategy to two main PM strategies—stratified medicine and (...)
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  11.  38
    Sages and Cranks.Katrina Hutchison - 2013 - In Katrina Hutchison & Fiona Jenkins (eds.), Women in Philosophy: What Needs to Change? New York: Oup Usa. pp. 103.
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  12.  7
    Depressive Thoughts Limit Working Memory Capacity in Dysphoria.Nicholas A. Hubbard, Joanna L. Hutchison, Monroe Turner, Janelle Montroy, Ryan P. Bowles & Bart Rypma - 2016 - Cognition and Emotion 30 (2):193-209.
  13.  6
    Justice and Surgical Innovation: The Case of Robotic Prostatectomy.Katrina Hutchison, Jane Johnson & Drew Carter - 2016 - Bioethics 30 (7):536-546.
    Surgical innovation promises improvements in healthcare, but it also raises ethical issues including risks of harm to patients, conflicts of interest and increased injustice in access to health care. In this article, we focus on risks of injustice, and use a case study of robotic prostatectomy to identify features of surgical innovation that risk introducing or exacerbating injustices. Interpreting justice as encompassing matters of both efficiency and equity, we first examine questions relating to government decisions about whether to publicly fund (...)
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  14.  10
    What Happened to Occult Qualities in the Scientific Revolution?Keith Hutchison - 1982 - Isis 73 (2):233-253.
  15.  41
    What Are Conditional Probabilities Conditional Upon?K. Hutchison - 1999 - British Journal for the Philosophy of Science 50 (4):665-695.
    This paper rejects a traditional epistemic interpretation of conditional probability. Suppose some chance process produces outcomes X, Y,..., with probabilities P(X), P(Y),... If later observation reveals that outcome Y has in fact been achieved, then the probability of outcome X cannot normally be revised to P(X|Y) ['P&Y)/P(Y)]. This can only be done in exceptional circumstances - when more than just knowledge of Y-ness has been attained. The primary reason for this is that the weight of a piece of evidence varies (...)
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  16. Knowledge and Ignorance in Economics.T. W. Hutchison - 1980 - British Journal for the Philosophy of Science 31 (1):98-104.
  17.  19
    Is Unconscious Identity Priming Lexical or Sublexical?K. Hutchison - 2004 - Consciousness and Cognition 13 (3):512-538.
    We examined unconscious priming in a stem-completion task with both identity and form-related primes. Participants were given exclusion instructions to avoid completing a stem with a briefly flashed masked word . In Experiment 1, priming of around 7% occurred for both identity and form-based primes at a 33 ms exposure duration. When examining only trials in which the participants failed to identify the prime, this effect increased to 12% for identity primes, but remained the same for form-based primes. In Experiment (...)
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  18.  11
    What Pacemakers Can Teach Us About the Ethics of Maintaining Artificial Organs.Katrina Hutchison & Robert Sparrow - 2016 - Hastings Center Report 46 (6):14-24.
    One day soon it may be possible to replace a failing heart, liver, or kidney with a long-lasting mechanical replacement or perhaps even with a 3-D printed version based on the patient's own tissue. Such artificial organs could make transplant waiting lists and immunosuppression a thing of the past. Supposing that this happens, what will the ongoing care of people with these implants involve? In particular, how will the need to maintain the functioning of artificial organs over an extended period (...)
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  19.  14
    Addressing Deficits and Injustices: The Potential Epistemic Contributions of Patients to Research.Katrina Hutchison, Wendy Rogers & Vikki A. Entwistle - 2017 - Health Care Analysis 25 (4):386-403.
    Patient or public involvement in health research is increasingly expected as a matter of policy. In theory, PPI can contribute both to the epistemic aims intrinsic to research, and to extrinsically valued features of research such as social inclusion and transparency. In practice, the aims of PPI have not always been clear, although there has been a tendency to encourage the involvement of so-called ordinary people who are regarded as representative of an assumed patient perspective. In this paper we focus (...)
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  20.  6
    Supernaturalism and the Mechanical Philosophy.K. Hutchison - 1983 - History of Science 21 (3):297-333.
  21. What Happened to Occult Qualities in the Scientific Revolution?Keith Hutchison - 1982 - Isis: A Journal of the History of Science 73:233-253.
     
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  22.  19
    Getting Clearer About Surgical Innovation : A New Definition and a New Tool to Support Responsible Practice.Katrina Hutchison, Wendy Rogers, Anthony Eyers & Mianna Lotz - unknown
    OBJECTIVES: This article presents an original definition of surgical innovation and a practical tool for identifying planned innovations. These will support the responsible introduction of surgical innovations. BACKGROUND: Frameworks developed for the safer introduction of surgical innovations rely upon identifying cases of innovation; oversight cannot occur unless innovations are identified. However, there is no consensus among surgeons about which interventions they consider innovative; existing definitions are vague and impractical. METHODS: Using conceptual analysis, this article synthesizes findings from relevant literature, and (...)
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  23.  34
    Dormitive Virtues, Scholastic Qualities, and the New Philosophies.Keith Hutchison - 1991 - History of Science 29 (3):245-278.
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  24.  6
    Idiosyncrasy, Achromatic Lenses, and Early Romanticism.Keith Hutchison - 1991 - Centaurus 34 (2):125-171.
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  25.  16
    Variability in Response Criteria Affects Estimates of Conscious Identification and Unconscious Semantic Priming☆.Jesse J. Bengson & Keith A. Hutchison - 2007 - Consciousness and Cognition 16 (4):785-796.
    Three experiments examined the role of response criteria in a masked semantic priming paradigm using an exclusion task. Experiment 1 used on-line prime-report and exclusion instructions in which participants were told to avoid completing a word stem with a word related to a prime flashed for 0, 38 or 212 ms. Semantic priming was significant in the items analysis, but was moderated by peoples’ ability to report the prime in the participant analysis. Prime-report thresholds in Experiment 2 were made more (...)
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  26.  9
    Scandals in Health-Care: Their Impact on Health Policy and Nursing.Jacqueline S. Hutchison - forthcoming - Nursing Inquiry:n/a-n/a.
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  27.  11
    Strengthening the Ethical Assessment of Placebo-Controlled Surgical Trials: Three Proposals.Wendy Rogers, Katrina Hutchison, Zoë C. Skea & Marion K. Campbell - 2014 - BMC Medical Ethics 15 (1):78.
    Placebo-controlled surgical trials can provide important information about the efficacy of surgical interventions. However, they are ethically contentious as placebo surgery entails the risk of harms to recipients, such as pain, scarring or anaesthetic misadventure. This has led to claims that placebo-controlled surgical trials are inherently unethical. On the other hand, without placebo-controlled surgical trials, it may be impossible to know whether an apparent benefit from surgery is due to the intervention itself or to the placebo effect.
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  28.  8
    Mayer's Hypothesis: A Study of the Early Years of Thermodynamics.Keith Hutchison - 1976 - Centaurus 20 (4):279-304.
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  29.  9
    Introduction : Searching for Sofia : Gender and Philosophy in the 21st Century.Fiona Jenkins & Katrina Hutchison - unknown
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  30. Planetary Distances as a Test for the Copernican Theory.Keith Hutchison - 1983 - British Journal for the Philosophy of Science 34 (4):369-371.
  31.  20
    Ultra-Deductivism From Nassau Senior to Lionel Robbins and Daniel Hausman.Terence Hutchison - 1998 - Journal of Economic Methodology 5 (1):43-91.
  32.  9
    The Effect of Hydrostatic Pressure on Yielding in Iron.F. P. Bullen, F. Henderson, M. M. Hutchison & H. L. Wain - 1964 - Philosophical Magazine 9 (98):285-297.
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  33.  69
    Moral Fables of Public Relations Practice: The Tylenol and Exxon Valdez Cases.John J. Pauly & Liese L. Hutchison - 2005 - Journal of Mass Media Ethics 20 (4):231 – 249.
    Discussions of the Tylenol and Exxon Valdez cases found in textbooks, public relations scholarship, and news coverage are assessed to understand the meanings that practitioners, educators, critics, and journalists have attributed to those events. The essay objects to a central claim made by critics who say these cases set standards for ethical behavior in public relations. This claim, according to us, mistakes moral drama for ethical deliberation.
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  34.  13
    On the Relations Between Philosophy and Economics: Part II: To What Kind of Philosophical Problems Should Economists Address Themselves?Terence W. Hutchison - 1997 - Journal of Economic Methodology 4 (1):127-151.
  35.  7
    Sunspots, Galileo, and the Orbit of the Earth.Keith Hutchison - 1990 - Isis: A Journal of the History of Science 81:68-74.
  36.  18
    Context and Perceptual Salience Influence the Formation of Novel Stereotypes Via Cumulative Cultural Evolution.Jacqui Hutchison, Sheila J. Cunningham, Gillian Slessor, James Urquhart, Kenny Smith & Douglas Martin - 2018 - Cognitive Science 42 (S1):186-212.
    We use a transmission chain method to establish how context and category salience influence the formation of novel stereotypes through cumulative cultural evolution. We created novel alien targets by combining features from three category dimensions—color, movement, and shape—thereby creating social targets that were individually unique but that also shared category membership with other aliens. At the start of the transmission chains each alien was randomly assigned attributes that described it. Participants were given training on the alien-attribute assignments and were then (...)
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  37.  1
    …And Three Centuries of Steam Power.Keith Hutchison - 2019 - Metascience 28 (2):193-196.
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  38.  5
    W. J. M. Rankine And The Rise Of Thermodynamics.Keith Hutchison - 1981 - British Journal for the History of Science 14 (1):1-26.
    In the history of thermodynamics, two dates stand out as especially important: 1824, when Sadi Carnot's brilliant memoir Réflexions sur la puissance motrice du feu appeared in print; and 1850, when Rudolf Clausius published his similarly titled paper ‘Ueber die bewegende Kraft der Wärme’. In this paper Clausius narrowly beat the Scottish physicist William Thomson to the solution of a puzzle which had been highlighted in the latter's recent publications: how could Carnot's theory, with all its intellectual attractions, be reconciled (...)
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  39.  3
    Dynamic Recovery From Strain-Hardening in Polycrystalline Copper and Aluminium.F. P. Bullen & M. M. Hutchison - 1962 - Philosophical Magazine 7 (76):557-572.
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  40.  67
    Temporal Asymmetry in Classical Mechanics.Keith Hutchison - 1995 - British Journal for the Philosophy of Science 46 (2):219-234.
    This paper argues against a standard view that all deterministic and conservative classical mechanical systems are time-reversible, by asking how the temporal evolution of a system modulates parametric imprecision (either ontological or epistemic). It notes that well-behaved systems (e.g. inertial motion) can possess a dynamics which is unstable enough to fail at reversing uncertainties—even though exact values are reliably reversed. A limited (but significant) source of irreversibility is thus displayed in classical mechanics, closely analogous the lack of predictability revealed by (...)
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  41.  27
    Leonard Ehrlich, "Karl Jaspers: Philosophy as Faith". [REVIEW]John Alexander Hutchison - 1978 - Journal of the History of Philosophy 16 (2):243.
  42.  54
    Human Behavior in the Social Environment.Elizabeth D. Hutchison & L. Charlesworth - 1998 - In Josefina Figueira-McDonough, Ann Nichols-Casebolt & F. Ellen Netting (eds.), The Role of Gender in Practice Knowledge: Claiming Half the Human Experience. Garland. pp. 1086--41.
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  43.  87
    Berkeley's Querist and its Place in the Economic Thought of the Eighteenth Century.T. W. Hutchison - 1953 - British Journal for the Philosophy of Science 4 (13):52-77.
  44.  13
    Der ursprung der entropiefunktion bei rankine und clausius.Keith Hutchison - 1973 - Annals of Science 30 (3):341-364.
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  45.  43
    Book Notes. [REVIEW]Herbert Wallace Schneider, A. R. Louch, Paul T. Fuhrmann & John Alexander Hutchison - 1967 - Journal of the History of Philosophy 5 (2):287-293.
  46.  19
    Hips, Knees, and Hernia Mesh: When Does Gender Matter in Surgery?Katrina Hutchison & Wendy Rogers - 2017 - Ijfab: International Journal of Feminist Approaches to Bioethics 10 (1):148-174.
    When implanted devices fail, the harms are significant. In addition to the patient’s original problem, the failure of the device can cause its own considerable damage, requiring removal of the implant and, in some cases, precipitating ongoing health problems. One recent high profile case of device failure is that of the metal-on-metal De Puy ASR hip replacement system, which left tens of thousands of people with cobalt-chromium toxicity and the need for a joint revision. Another concerns tissue repair mesh products (...)
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  47.  21
    Review Symposia.Martin Rudwick, Naomi Oreskes, David Oldroyd, David Philip Miller, Alan Chalmers, John Forge, David Turnbull, Peter Slezak, David Bloor, Craig Callender, Keith Hutchison, Steven Savitt & Huw Price - 1996 - Metascience 5 (1):7-85.
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  48.  23
    A Question of Priorities: Forbes, Agassiz, and Their Disputes on Glacier Observations.Ian Campbell & David Hutchison - 1978 - Isis 69 (3):388-399.
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  49.  37
    What the Nuns Read: Literary Evidence From the English Bridgettine House, Syon Abbey.Ann M. Hutchison - 1995 - Mediaeval Studies 57 (1):205-222.
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  50.  15
    Differing Criteria for Temporal Symmetry.Keith Hutchison - 1995 - British Journal for the Philosophy of Science 46 (3):341-347.
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