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  1. An Organizational Account of Biological Functions.Matteo Mossio, Cristian Saborido & Alvaro Moreno - 2009 - British Journal for the Philosophy of Science 60 (4):813-841.
    In this paper, we develop an organizational account that defines biological functions as causal relations subject to closure in living systems, interpreted as the most typical example of organizationally closed and differentiated self-maintaining systems. We argue that this account adequately grounds the teleological and normative dimensions of functions in the current organization of a system, insofar as it provides an explanation for the existence of the function bearer and, at the same time, identifies in a non-arbitrary way the norms that (...)
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  2.  89
    Biological Organization and Cross-Generation Functions.Cristian Saborido, Matteo Mossio & Alvaro Moreno - 2011 - British Journal for the Philosophy of Science 62 (3):583-606.
    The organizational account of biological functions interprets functions as contributions of a trait to the maintenance of the organization that, in turn, maintains the trait. As has been recently argued, however, the account seems unable to provide a unified grounding for both intra- and cross-generation functions, since the latter do not contribute to the maintenance of the same organization which produces them. To face this ‘ontological problem’, a splitting account has been proposed, according to which the two kinds of functions (...)
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  3.  15
    Functions, Organization and Etiology: A Reply to Artiga and Martinez.Cristian Saborido & Matteo Mossio - 2016 - Acta Biotheoretica 64 (3):263-275.
    We reply to Artiga and Martinez’s claim according to which the organizational account of cross-generation functions implies a backward looking interpretation of etiology, just as standard etiological theories of function do. We argue that Artiga and Martinez’s claim stems from a fundamental misunderstanding about the notion of “closure”, on which the organizational account relies. In particular, they incorrectly assume that the system, which is relevant for ascribing cross-generation organizational function, is the lineage. In contrast, we recall that organizational closure refers (...)
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  4.  63
    Disease-Mongering Through Clinical Trials.María González-Moreno, Cristian Saborido & David Teira - 2015 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 51:11-18.
    Why scientists reach an agreement on new experimental methods when there are conflicts of interest about the evidence they yield? I argue that debiasing methods play a crucial role in this consensus, providing a warrant about the impartiality of the outcome regarding the preferences of different parties involved in the experiment. From a contractarian perspective, I contend that an epistemic pre-requisite for scientists to agree on an experimental method is that this latter is neutral regarding their competing interests. I present (...)
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  5.  45
    Biological Pathology From an Organizational Perspective.Cristian Saborido & Alvaro Moreno - 2015 - Theoretical Medicine and Bioethics 36 (1):83-95.
    In contrast to the “normativist” view, “naturalist” theorists claim that the concept of health refers to natural or normal states and propose different characterizations of healthy and diseased conditions that are meant to be objectivist and biologically grounded. In this article, we examine the core concept of these naturalist accounts of disease, i.e., the concept of biological malfunction, and develop a new formulation of the notion of malfunction following the recent organizational approach to functions in the philosophy of biology. We (...)
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  6.  15
    Intervalos de cuasi-descomponibilidad y propiedades emergentes.Emilio Cáceres Vázquez & Cristian Saborido - 2017 - Theoria: Revista de Teoría, Historia y Fundamentos de la Ciencia 32 (1):89-108.
    La noción de emergencia acompaña a la Filosofía de la Biología desde finales del siglo XIX, afirmando que las propiedades de los sistemas biológicos no pueden deducirse de las de sus componentes. A lo largo del siglo XX las caracterizaciones de este concepto se han apoyado en cuatro pilares, impredecibilidad, novedad, restricción y causación descendente, pilares ligados a la asunción de una jerarquización de la realidad en niveles de organización. En este trabajo intento demostrar que puede explicarse la naturaleza de (...)
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  7.  13
    ¿Realmente mató la bacteria al coronel?Emilio Cáceres Vázquez & Cristian Saborido - 2018 - Theoria: Revista de Teoría, Historia y Fundamentos de la Ciencia 33 (1):129-148.
    En este trabajo analizamos críticamente el enfoque mecanicista de explicación científica centrándonos principalmente en la forma en la que este da cuenta de los fenómenos biológicos. Nos proponemos complementar esta perspectiva con una concepción de nivel como intervalo de cuasi-descomponibilidad que nos permite fundamentar metafísicamente las propuestas mecanicistas clásicas en las propiedades sistémicas características de las entidades biológicas. A través del análisis de ejemplos concretos, demostraremos cómo nuestra propuesta permite superar algunas de las limitaciones de los enfoques predominantes de explicación (...)
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  8.  3
    Incommensurability and the Extended Evolutionary Synthesis: taking Kuhn seriously.Juan Gefaell & Cristian Saborido - 2022 - European Journal for Philosophy of Science 12 (2):1-25.
    In this paper, we analyze the debate between the Modern Synthesis and the Extended Evolutionary Synthesis in light of the concept of incommensurability developed by Thomas Kuhn. In order to do so, first we briefly present both the Modern Synthesis and the Extended Evolutionary Synthesis. Then, we clarify the meaning and interpretations of incommensurability throughout Kuhn’s works, concluding that the version of this concept deployed in The Structure of Scientific Revolutions is the best suited to the analysis of scientific disputes. (...)
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  9.  41
    De la selección natural al diseño: una propuesta de extensión del darwinismo formal.Giorgio Airoldi & Cristian Saborido - 2017 - Metatheoria – Revista de Filosofía E Historia de la Ciencia 8 (1):71--80.
    Darwin’s claim that Natural Selection, through optimization of fitness, explains complex biological design has not yet been properly formalized. Alan Grafen’s Formal Darwinism Project aims at providing such a formalization and at demonstrating that fitness maximization is coherent with results from Population Genetics, usually interpreted as denying it. We suggest that Grafen’s proposal suffers from some limitations linked to its concept of design as optimized fitness. In order to overcome these limitations, we propose a classification of evolutionary facts based on (...)
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  10. Cultura bioética y conceptos de enfermedad: el caso House.Antonio da Rocha & Cristian Saborido - 2010 - Isegoría 42:279-295.
    En la intersección entre la ética aplicada y los estudios sobre divulgación científica en los medios, este trabajo propone un concepto de «cultura bioética» y lo aplica a la exitosa serie de televisión House. Nuestro análisis de la serie muestra la relación existente entre la tensión entre autonomía del paciente y paternalismo médico presente en la teoría bioética y la práctica asistencial, por un lado, con el debate abierto en filosofía de la medicina entre posiciones naturalistas y normativistas sobre los (...)
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  11. A vueltas con la teleología en ciencias sociales.Cristian Saborido & José Francisco Alvarez - 2012 - Diálogo Filosófico 83 (83):53-72.
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  12. Proceedings of the IX Conference of the Spanish Society of Lógic, Methodology and Philosophy of Science.Cristian Saborido, Sergi Oms & Javier González de Prado (eds.) - 2018
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  13.  6
    La guerra de la Naturaleza, la carestía y la muerte como fuente del diseño de los seres vivos.Giorgio Airoldi & Cristian Saborido - 2020 - Endoxa 46:123.
    El proyecto del ‘Darwinismo Formal’ de Alan Grafen propone una formulación matemática de la teoría de Darwin que pretende demostrar que la selección natural moldea los rasgos fenotípicos a través de la maximización de la eficacia. El proyecto de Grafen reposa sobre tres premisas: la selección natural es la única fuerza que moldea los fenotipos; la eficacia es la única medida de le evolución; y el diseño biológico surge como resultado de un proceso de optimización selectiva. En este trabajo argumentamos (...)
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  14.  9
    Did the Bacterium Really Kill the Colonel? Systemic View, Inter-Level Causation, and Levels of Quasi-Decompositionality in Mechanistic Explanations.Emilio Cáceres Vázquez & Cristian Saborido - 2018 - Theoria : An International Journal for Theory, History and Fundations of Science 33 (1):129-148.
    In this paper, we critically analyze the mechanicist approach to scientific explanation and propose to complement this view with a conception of level as interval of quasi-decompositionality. This conception allows us to metaphysically base the mechanicist proposals on characteristic systemic features. By means of concrete examples, we claim that this proposal is able to overcome some of the alleged limitations of predominant models of mechanistic explanation.
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  15.  9
    Intervals of Quasi-Decompositionality and Emergent Properties.Emilio Cáceres Vázquez & Cristian Saborido - 2017 - Theoria : An International Journal for Theory, History and Fundations of Science 32 (1):89-108.
    The notion of emergence has accompanied philosophy of science since the late XIX century, claiming that in some systems there are properties in certain levels that cannot be deduced from properties of their components as seen in more fundamental levels. Throughout the XX century, emergence has been characterized by four pillars: unpredictability, novelty, restriction and downward causation. These four pillars have been related to the assumption of a hierarchical order of reality in different levels of organization. In this paper, we (...)
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  16.  6
    Morir Para Vivir. La Muerte Celular Como Proceso Regulador.María Belén Campero, Cristián Favre & Cristian Saborido - forthcoming - Theoria. An International Journal for Theory, History and Foundations of Science.
    Usually, the organization of living systems is explained by appealing to an intrinsic purpose that is based on the biological survival. However, paradigmatically, it is inevitable to observe that the final destiny of all living organisms is death. In this work, we defend that, from an organizational approach, there is a form of death—Regulatory Cell Death—that, far from being a mere "absence of life", is a process of biological regulation and a feature of self-maintenance in multicellular organisms.
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  17. La dimensión teleologica del concepto de función biológica.Cristian Saborido, Matteo Mossio & Alvaro Moreno - 2010 - Teorema: International Journal of Philosophy 29 (3):31-56.
    Most of current theoretical analyses on biological functions can be classified as etiological or dispositional, depending on how they deal with the teleological dimension. In this paper, we propose a critical survey of these two perspectives, and we argue that some recent studies have set the basis of a new approach which grounds the teleological dimension of functional attributions in the organizational properties of living systems. We outline a new proposal within this new approach, based on an interpretation of living (...)
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  18.  10
    Cultura bioética y conceptos de enfermedad: el caso House.Antonio Casado da Rocha & Cristian Saborido - 2010 - Isegoría 42:279-295.
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  19. In Search of Conceptual Bridges: A Review of Krohs, U. & Kroes, P. "Functions in Biological and Artificial Worlds".Cristian Saborido, Matteo Mossio & Kepa Ruiz-Mirazo - 2010 - Artificial Life 16 (4):337-340.
     
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  20.  3
    Justin Garson, What Biological Functions Are and Why They Matter, Cambridge: Cambridge University Press, 2019. [REVIEW]Cristian Saborido - 2021 - History and Philosophy of the Life Sciences 43 (1):1-3.
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  21.  1
    Morir para vivir. La muerte celular como proceso regulador.María Belén Campero, Cristián Favre & Cristian Saborido - 2020 - Theoria: Revista de Teoría, Historia y Fundamentos de la Ciencia 35 (2):197-215.
    Usually, the organization of living systems is explained by appealing to an intrinsic purpose that is based on the biological survival. However, paradigmatically, it is inevitable to observe that the final destiny of all living organisms is death. In this work, we defend that, from an organizational approach, there is a form of death—Regulated Cell Death—that, far from being a mere «absence of life», is a process of biological regulation and a feature of self-maintenance in multicellular organisms.
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