Il sistema morale e l'agire umano secondo San Tommaso -- Il concetto di legge nella dottrina tomista -- La grazia e le virtù -- La conoscenza della giustizia -- Il pensiero politico di san Tommaso.

Alzheimer's disease (AD) is the most common cause of dementia, and there is currently no cure. The “β‐amyloid cascade hypothesis” of AD is the basis of current understanding of AD pathogenesis and drug discovery. However, no AD models have fully validated this hypothesis. We recently developed a human stem cell culture model of AD by cultivating genetically modified human neural stem cells in a three‐dimensional (3D) cell culture system. These cells were able to recapitulate key events of AD pathology including (...) β‐amyloid plaques and neurofibrillary tangles. In this review, we will discuss the progress and current limitations of AD mouse models and human stem cell models as well as explore the breakthroughs of 3D cell culture systems. We will also share our perspective on the potential of dish models of neurodegenerative diseases for studying pathogenic cascades and therapeutic drug discovery. (shrink)

This article describes three characteristics of the Japanese Leadership Style (JLS): self-realization, appreciation of diverse abilities, and trust in others, which have both positive and negative ethical implications. In addition to illustrating how JLS allows Japanese corporations to avoid some of the ethical problems plaguing U.S. corporations, the authors will explain how these characteristics engender the loyalty and initiative of Japanese employees which promote incremental innovation and competitive advantages. Implicit in this discussion is the premise that both the American and (...) Japanese business communities, by analyzing their own ethical issues and leadership styles, can learn from each other. (shrink)

Résumé Cet article se veut une chronique de la partition de la Moldavie en deux républiques après la brève guerre du Dniestr de 1992. Il s’agit principalement d’un récit établi à partir de notes de terrain recueillies en juin 1993 auprès de témoins et acteurs de ce drame. Ses conséquences ont relégué la Moldavie, florissante république soviétique, bien connue pour ses vins de qualité et ses produits industriels spécifiques au sein d’un grand complexe militaro-industriel, au rang de l’une des plus (...) pauvres entités post-soviétiques, aux prises avec de terribles problèmes de survie. Nombre de ses habitants ont été jetés sur les routes de tous les trafics (drogue, prostitution, travail clandestin). Cette chronique et ses commentaires entendent mettre en lumière l’exacerbation des tensions qui est survenue entre la fin de la perestroïka et l’implosion de l’URSS – période de confusion des loyautés, de crises interethniques et nationalistes, et de tractations troubles entre grandes puissances pour le partage de leurs zones d’influence. (shrink)

Résumé Ce texte explicite l’objectif du présent numéro sur les frontières et les identités mouvantes. Il situe cette interrogation dans le contexte de la constitution de blocs macro-régionaux et de la fin de la bipolarité. Il tend à montrer les incidences d’un tel contexte sur le fonctionnement des zones frontalières et celui des identités qu’elles ont forgées au cours du temps long de l’histoire moderne. Cet article voudrait mettre en évidence l’émergence du dogmatisme de la religion du capital sous les (...) nouveaux visages d’un culturalisme anthropologique multiforme. Sous l’effet d’une médiatisation sans précédent au plan mondial, ce dernier semble bien devenir la nouvelle grille de lecture des grands évènements du monde dont s’emparent, sans vrai discernement, nombre d’acteurs du politique. L’un des principaux traits de notre recueil d’articles est de mettre en avant que les auteurs qui y ont contribué, tout en appartenant à différentes écoles de pensée, ont tous cherché à s’en démarquer ou à en montrer tout au moins les limites. Pour terminer, en s’inspirant de l’œuvre de Jacques Derrida, il souhaiterait livrer certaines clés de lecture et de compréhension. (shrink)

Rendre hommage à un auteur, ce n'est pas seulement célébrer ce qu'il fut mais c'est aussi alerter sur ce que son oeuvre apporte au présent et à l'avenir de la connaissance. C'est bien le sens donné à cet hommage à André-Jean Arnaud. Repenser le droit, c'était pou r cet auteur érudit : repenser les lieux, les conditions et les façons de l'étudier en dépassant les frontières géographiques en même temps que les frontières disciplinaires. En montrant en quoi André-Jean Arnaud fut, (...) hors des sentiers battus et des orthodoxies de la production et de la transmission des savoirs en la matière, un exceptionnel précurseur et l'infatigable artisan d'un nouveau régime de connaissance sur le droit, le présent ouvrage s'adresse à toutes celles et à tous ceux, enseignants, chercheurs, étudiants ou simples citoyens, pou r qui l'étude du droit permet de mieux comprendre ce que sont et ce que sont susceptibles de devenir nos sociétés. (shrink)

"Practice in Christianity is the second volume in what could be called the "collected Works" of "Anti-Climacus," Kierkegaard's new pseudonym. Anti-Climacus's first volume, The Sickness Unto Death, appeared just a year earlier in 1849. The use of a pseudonym is consistent with Kierkegaard's usual practice when presenting an idealized statement of his subject, be it sexual seduction or Christian theology. Anti-Climacus argues the conceptual content of Christianity against the "leading thought of the times" and also against the ethical and social (...) import of the comforts and consolations of bourgeois culture and religion which he called "Christendom." In his own mind at least, Kierkegaards presents Christianity as it must be thought and lived if it is to be authentic. The Sickness unto Death and Practice in Christianity can be and are read quite independently, but jointly they provide the basis of Kierkegaard's devastating critique of a secularized, culturally homogenized, and tame Christianity. The authors of the studies in this present volume, Merold Westphal, Paul R. Sponheim, Murray A. Rae, Niels Jorgen Cappelorn, Sylvia Walsh, David D. Possen, Andrew J. Burgess, Christian Fink Tolstrup, Robert L. Perkins, and Wanda Warren Berry, raise a wide spectrum of issues regarding Practice in Christianity, its theology, its moral and religious psychology, and its cultural, social, and political world" --. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:François H. Lapointe PHILOSOPHY AND LITERATURE: A BIBLIOGRAPHIC SURVEY ThL· survey is limited to articles written in English that have appeared in journals published between 1 January 1974 and 31 December 1976. Abbott, Don. "Marxist Influences on the Rhetorical Theory of Kenneth Burke." Philosophy and Rhetoric 7 (1974): 217-33. Abel, Lionel. "Jacques Derrida: His 'Difference' With Metaphysics." Salmagundi no. 25 (1974): 3-21. Adamowski, T. H. "Character and Consciousness: D. (...) H. Lawrence, Wilhelm Reich, and Jean-Paul Sartre." University of Toronto Quarterly 43 (1974): 31 1-34. Adams, D. J. "Style and Social Ideas in Jacques le fataliste." Studies in Voltaire & the Eighteenth Century 124 (1974): 231-48. Adams, Hazard. "Contemporary Ideas of Literature: Terrible Beauty or Rough Beast?" Contemporary Literature 17 (1976): 349-77. Adorno, Theodor W. "Lyric Poetry and Society." Telos no. 20 (1974): 56-71. Ages, Arnold. "Bonald and the Jews." Revue de l'Université d'Ottawa 44 (1974): 32-43. Allen, Diogenes. "The Experience of Existence: Jean-Paul Sartre and Iris Murdoch." International Philosophical Quarterly 14 (1974): 181-87. Allen, Marcus. "Character Development in the Oreste of Voltaire and Les Mouches of Jean-Paul Sartre." CLA Journal 18 (1974): 1-21. Alter, Jean. "A (Terrorist) System of the Novel." Diacritics 6 (1976): 10-15. Altieri, Charles. "Wittgenstein on Consciousness and Language: A Challenge to Derridean Literary Theory." MLN 91 (1976): 1397-1423. Altieri,Charles. "Wordsworth's 'Preface' as Literary Theory." Criticism 18 (1976): 122-146. [On Wordworth and Wittgenstein.] Ames, Van Meter. "Art for Art's Sake Again?" Journal of Aesthetics and Art Criticism 33 (1975): 303-307. Appleman, Philip. "The Dread Factor: Eliot, Tennyson, and the Shaping of Science." Columbia Forum, N. S. 3 (1974): 32-38. Armstrong, Paul B. " E. M. Forster's Howard's End: The Existential Crisis of the Liberal Imagination." Mosaic 8 (1974): 183-99. Arnold, A. James. "La Condition humaine as Nietzschean Tragedy." Mélanges Malraux Miscellany 6 (1974): 15-24. 366 François H. Lapointe367 Aronson, Ronald. "L'Idiot de la famille: The Ultimate Sartre?" Telos no. 20 (1974): 90-107. Arthos, John. "Du Bartas, Petrarch and the Poetry of Deism." Rice University Studies 60 (1974): 1-17. Artz, Johannes. "Newman as Philosopher." International Philosophical Quarterly 16 (1976): 263-88. Ausmus, Harry J. "Schopenhauer's Philosophy of Language." The Midwest Quarterly 18 (1977): 169-86. Ayala, Francisco. "Ortega y Gasset, Literary Critic." Critical Inquiry 1 (1974): 395-414. Bakalar, H. Nicholas. "The Cartesian Legacy to the Eighteenth-century Grammarians." MLN 91 (1976): 698-721. Barnes, Hazel. "Apotheosis and Deification in Plato, Nietzsche and Huxley." Philosophy and Literature 1 (1976): 3-24. Baron, Dennis E. "Role Structure and the Language of Literature." Journal of Literary Semantics 4 (1975): 43-52. Barooskian, Vahan D. "The Aesthetics of the Russian Revolutionary Theatre 1917-1921." British Journal of Aesthetics 15 (1975): 99-117. Bart, B. F. "Hypercreativity in Stendhal and Balzac." Nineteenth Century French Studies 3 (1974-75): 18-39. Barthes, Roland. "An Introduction to the Structural Analysis of Narrative." New Literary History 6 (1975): 237-72. Bashford, Bruce. "The Rhetorical Method in Literary Criticism." Philosophy and Rhetoric 9 (1976): 133-46. Bass, Alan. "Time and the Witch: Femininity, Metapsychology and the Temporality of the Unconscious." MLN 91 (1976): 871-912. Bassett, Sharon. "Towards a Critique of Romanticism: Wordsworth, Pater and the 'Anima Mundi'." Criticism 17 (1975): 262-75. Batchelor, R. "Literature, Society and the Concept of Revolt." European Studies Review 5 (1975): 395-427. Battin, M. Pabst. "Aristotle's Definition of Tragedy in the Poetics, Part 1." Journal of Aesthetics and Art Criticism 33 (1974): 155-70, and Part II in Ibid. 33 (1975): 293-302. Bauer, George. "Sartre and the 'Sugars' of History." L'Esprit Créateur 15 (1975): 377-86. Baumgarten, Murray. "The Historical Novel: Some Postulates." Clio 4 (1975): 173-82. Beauchamp, Gorman. "Gulliver's Return to the Cave: Plato's Republic and Book IV of Gulliver's Travels." The Michigan Academician 7 (1974): 201-10. Bennett, Jonathan. "The Conscience of Huckleberry Finn." Philosophy 48 (1974): 123-34. Benzon, William. "Cognitive Networks and Literary Semantics." MLN 91 (1976): 952-82. Bergonzi, Bernard. "A Grid of Codes: Views of Structuralism." Encounter 45 (1975): 52-58. Berry, Wanda Warren. "The... (shrink)

When surveying recent philosophical work on the nature and status of collective intentionality and we-intentions, it is striking how much effort is spent on analysing the structure of joint action and on establishing whether or not the intention to, say, go for a walk or paint a house together is reducible to some form of I-intentionality. Much less work has been devoted to an analysis of shared affects and emotions. This is regrettable, not only because emotional sharing in all likelihood (...) is developmentally prior to and logically more basic than joint action, but also because it might constitute a way of being together with others, which we need to study if we wish to better understand the nature of the we. In the present contribution, my primary aim will be to offer an answer to the following question: does the we-experience, the experience of being part of a we, presuppose, precede, preserve, or abolish the difference between self- and other-experience? In pursuing this task, I will take a closer look at emotional sharing and draw on resources that are too frequently ignored in current social ontology, namely insights found in classical phenomenology and in contemporary research on social cognition. (shrink)

A stream of conscious experience is extremely contextual; it is impacted by sensory stimuli, drives and emotions, and the web of associations that link, directly or indirectly, the subject of experience to other elements of the individual's worldview. The contextuality of one's conscious experience both enhances and constrains the contextuality of one's behavior. Since we cannot know first-hand the conscious experience of another, it is by way of behavioral contextuality that we make judgements about whether or not, and to what (...) extent, a system is conscious. Thus we believe that a deep understanding of contextuality is vital to the study of consciousness. Methods have been developed for handling contextuality in the microworld of quantum particles. Our goal has been to investigate the extent to which these methods can be used to analyze contextuality in conscious experience. (shrink)

Upshot: In our target article we claimed that, at least since Weber and Varela, enactivism has incorporated a theoretical commitment to one important aspect of Jonas’s philosophical biology, namely its anthropomorphism, which is at odds with the methodological commitments of modern science. In this general reply we want to clarify what we mean by anthropomorphism, and explain why we think it is incompatible with science. We do this by spelling out what we call the “Jonasian inference,” i.e., the idea that (...) we are entitled, based on our first-person experience of teleology, to take the appearance of teleology in other living beings at face value. (shrink)

Résumé Michèle Le Dœuff est une philosophe qui a beaucoup contribué aux études beauvoiriennes, mais dont l’ apport a été sous-évalué. Pourtant, Le Dœuff a été la première à faire un travail critique, philosophique et féministe autour du Deuxième Sexe, d’ abord dans son célèbre article « Cheveux longs, idées courtes » (1977), puis de façon plus approfondie dans L’ Étude et le rouet (1989). Les études beauvoiriennes ont sans doute encore beaucoup à puiser dans l’ œuvre de Le Dœuff.

Excerpt: In 1995, the Leo Apostel Centre in Brussels, Belgium, organised an international conference called ``Einstein meets Magritte''. Nobel prize winner Ilya Prigogine held the opening lecture at the conference, and Heinz von Foerster's lecture was scheduled last... Heinz von Foerster was enchanted by the conference theme and -- in the spirit of surrealist Belgian painter René Magritte -- had chosen an appropriate title for his talk: ``Ceci n'est pas Albert Einstein''. ... [H]e was delighted to grant the organisers the (...) following interview, in which he tells us about an even longer journey -- that of his remarkable life and scientific career. (shrink)