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Daniel Strech [23]D. Strech [6]
  1.  18
    Standards of Practice in Empirical Bioethics Research: Towards a Consensus.Jonathan Ives, Michael Dunn, Bert Molewijk, Jan Schildmann, Kristine Bærøe, Lucy Frith, Richard Huxtable, Elleke Landeweer, Marcel Mertz, Veerle Provoost, Annette Rid, Sabine Salloch, Mark Sheehan, Daniel Strech, Martine de Vries & Guy Widdershoven - 2018 - BMC Medical Ethics 19 (1):68.
    Background This paper reports the process and outcome of a consensus finding project, which began with a meeting at the Brocher Foundation in May 2015. The project sought to generate and reach consensus on standards of practice for Empirical Bioethics research. The project involved 16 academics from 5 different European Countries, with a range of disciplinary backgrounds. Methods The consensus process used a modified Delphi approach. Results Consensus was reached on 15 standards of practice, organised into 6 domains of research (...)
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  2.  29
    How to Write a Systematic Review of Reasons.D. Strech & N. Sofaer - 2012 - Journal of Medical Ethics 38 (2):121-126.
    Systematic reviews, which were developed to improve policy-making and clinical decision-making, answer an empirical question based on a minimally biased appraisal of all the relevant empirical studies. A model is presented here for writing systematic reviews of argument-based literature: literature that uses arguments to address conceptual questions, such as whether abortion is morally permissible or whether research participants should be legally entitled to compensation for sustaining research-related injury. Such reviews aim to improve ethically relevant decisions in healthcare, research or policy. (...)
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  3.  36
    Reasons Why Post-Trial Access to Trial Drugs Should, or Need Not Be Ensured to Research Participants: A Systematic Review.N. Sofaer & D. Strech - 2011 - Public Health Ethics 4 (2):160-184.
    Background : researchers and sponsors increasingly confront the issue of whether participants in a clinical trial should have post-trial access (PTA) to the trial drug. Legislation and guidelines are inconsistent, ambiguous or silent about many aspects of PTA. Recent research highlights the potential importance of systematic reviews (SRs) of reason-based literatures in informing decision-making in medicine, medical research and health policy. Purpose: to systematically review reasons why drug trial participants should, or need not be ensured PTA to the trial drug (...)
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  4.  32
    How Physicians Allocate Scarce Resources at the Bedside: A Systematic Review of Qualitative Studies.D. Strech, M. Synofzik & G. Marckmann - 2008 - Journal of Medicine and Philosophy 33 (1):80-99.
    Although rationing of scarce health-care resources is inevitable in clinical practice, there is still limited and scattered information about how physicians perceive and execute this bedside rationing (BSR) and how it can be performed in an ethically fair way. This review gives a systematic overview on physicians’ perspectives on influences, strategies, and consequences of health-care rationing. Relevant references as identified by systematically screening major electronic databases and manuscript references were synthesized by thematic analysis. Retrieved studies focused on themes that fell (...)
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  5. Are Physicians Willing to Ration Health Care? Conflicting Findings in a Systematic Review of Survey Research.Daniel Strech, Govind Persad, Georg Marckmann & Marion Danis - 2009 - Health Policy 90 (2):113-124.
    Several quantitative surveys have been conducted internationally to gather empirical information about physicians’ general attitudes towards health care rationing. Are physicians ready to accept and implement rationing, or are they rather reluctant? Do they prefer implicit bedside rationing that allows the physician–patient relationship broad leeway in individual decisions? Or do physicians prefer strategies that apply explicit criteria and rules?
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  6.  29
    Quality of Ethical Guidelines and Ethical Content in Clinical Guidelines: The Example of End-of-Life Decision-Making.D. Strech & J. Schildmann - 2011 - Journal of Medical Ethics 37 (7):390-396.
    Background While there are many guidelines on how to make ethical decisions at the end of life, there is little evidence regarding the quality of this sort of ethical guidelines. Objectives First, this study aims to demonstrate the conceptual transferability of the Appraisal of Guidelines for Research and Evaluation (AGREE) instrument for the quality assessment of ethical guidelines. Second, it aims to illustrate the status quo of the quality of guidelines on end-of-life decision-making by using the AGREE instrument in a (...)
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  7.  11
    Evidence-Based Ethics – What It Should Be and What It Shouldn't.Daniel Strech - 2008 - BMC Medical Ethics 9 (1):16-.
    BackgroundThe concept of evidence-based medicine has strongly influenced the appraisal and application of empirical information in health care decision-making. One principal characteristic of this concept is the distinction between "evidence" in the sense of high-quality empirical information on the one hand and rather low-quality empirical information on the other hand. In the last 5 to 10 years an increasing number of articles published in international journals have made use of the term "evidence-based ethics", making a systematic analysis and explication of (...)
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  8.  31
    Systematic Reviews of Empirical Bioethics.D. Strech, M. Synofzik & G. Marckmann - 2008 - Journal of Medical Ethics 34 (6):472-477.
    Background: Publications and discussions of survey research in empirical bioethics have steadily increased over the past two decades. However, findings often differ among studies with similar research questions. As a consequence, ethical reasoning that considers only parts of the existing literature and does not apply systematic reviews tends to be biased. To date, we lack a systematic review (SR) methodology that takes into account the specific conceptual and practical challenges of empirical bioethics. Methods: The steps of systematically reviewing empirical findings (...)
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  9.  34
    The Need for Systematic Reviews of Reasons.Neema Sofaer & Daniel Strech - 2012 - Bioethics 26 (6):315-328.
    There are many ethical decisions in the practice of health research and care, and in the creation of policy and guidelines. We argue that those charged with making such decisions need a new genre of review. The new genre is an application of the systematic review, which was developed over decades to inform medical decision-makers about what the totality of studies that investigate links between smoking and cancer, for example, implies about whether smoking causes cancer. We argue that there is (...)
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  10.  17
    Why the “Appraisal of Guidelines for Research and Evaluation” Instrument Can and Should Further Inform Ethics Policy Work.Daniel Strech & Jan Schildmann - 2012 - American Journal of Bioethics 12 (11):25-27.
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  11.  41
    Der Umgang MIT Wahrscheinlichkeiten Und Das Vertrauen in Die MedizinDealing with Probabilities and Confidence in Medicine.Daniel Strech - 2005 - Ethik in der Medizin 17 (2):103-113.
    „Früh entdecken, effizienter therapieren!“ — Die innereLogik des Früherkennungskonzeptes ist äußerst öffentlichkeitswirksam und wird von den unterschiedlichsten medizinischen und gesellschaftlichen Institutionen unterstützt. In dieser Arbeit werden die vorrangig medizin-ethischen und wissenschaftstheoretischen Bedingungen untersucht, die erfüllt sein müssten, damit sich die Theorie einer Krebsfrüherkennung zum Wohl des Patienten umsetzen lässt: Wer ist kompetent, den jeweils stochastisch zu interpretierenden Nutzen und Schaden adäquat gegeneinander abzuwägen? Was sind angemessene Evaluationsparameter? Gibt es Grenzen der Informationsvermittlung in einer partnerschaftlichen Arzt-Patienten-Beziehung? Vor dem Hintergrund der früherkennungsspezifischen (...)
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  12.  26
    How Can Bedside Rationing Be Justified Despite Coexisting Inefficiency? The Need for 'Benchmarks of Efficiency'.Daniel Strech & Marion Danis - 2014 - Journal of Medical Ethics 40 (2):89-93.
    Imperfect efficiency in healthcare delivery is sometimes given as a justification for refusing to ration or even discuss how to pursue fair rationing. This paper aims to clarify the relationship between inefficiency and rationing, and the conditions under which bedside rationing can be justified despite coexisting inefficiency. This paper first clarifies several assumptions that underlie the classification of a clinical practice as being inefficient. We then suggest that rationing is difficult to justify in circumstances where the rationing agent is or (...)
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  13.  17
    How Factual Do We Want the Facts? Criteria for a Critical Appraisal of Empirical Research for Use in Ethics.D. Strech - 2010 - Journal of Medical Ethics 36 (4):222-225.
    Most contributions to the current debate about the consideration and application of empirical information in ethics scholarship deal with epistemological issues such as the role and the meaning of empirical research in ethical reasoning. Despite the increased publication of empirical data in ethics literature we still lack systematic analyses and conceptual frameworks that would help us to understand the rarely discussed methodological and practical problems in appraising empirical research. This paper demonstrates the need for critical appraisal and its crucial methodological (...)
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  14.  15
    Evidenz-basierte Ethik.Daniel Strech - 2008 - Ethik in der Medizin 20 (4):274-286.
    Mit dem Konzept der Evidenz-basierten Medizin wurde die Verwendungsweise von empirischen Informationen in den Gesundheitswissenschaften stark verändert. Ein grundlegendes Charakteristikum dieses Konzeptes ist die Unterscheidung zwischen empirischen Informationen per se und „Evidenzen“ im Sinne von qualitativ hochwertigeren empirischen Informationen. Dieses Konzept der Evidenzbasierung findet sich zunehmend auch im Kontext der angewandten Ethik. In der internationalen Fachpresse sind in den letzten 5 bis 10 Jahren zunehmend Arbeiten publiziert worden, die den Begriff „Evidenz-basierte Ethik“ in unterschiedlicher Weise verwenden. Um die ethisch akzeptable (...)
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  15.  26
    Zur Ethik Einer Restriktiven Regulierung der StudienregistrierungThe Ethics of a Restrictive Regulation of Trial Registration.Daniel Strech - 2011 - Ethik in der Medizin 23 (3):177-189.
    Seit vielen Jahren zeigen Untersuchungen, dass die Ergebnisse klinischer Studien häufig selektiv publiziert werden mit einer statistisch signifikanten und im klinischen Ausmaß sehr bedeutenden Übervorteilung positiver Studienergebnisse. Diese selektive Publikation führt zu einer systematischen Fehlleitung verschiedener medizinischer Entscheidungen bzw. der diesen Entscheidungen zu Grunde liegenden Nutzen-Schaden-Abwägungen. Man muss davon ausgehen, dass solche Fehlleitungen die Patientenversorgung, die Patientenaufklärung, den Probandenschutz und die medizinische Lehre verschlechtern und somit in vielerlei Hinsicht ethisch unakzeptable Konsequenzen haben. Studienregister stellen die international bevorzugte Strategie dar, um (...)
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  16.  18
    The Contribution and Attitudes of Research Ethics Committees to Complete Registration and Non-Selective Reporting of Clinical Trials: A European Survey.Daniel Strech, Jasper Littmann & on Behalf of the Open Consortium - 2016 - Research Ethics 12 (3):123-136.
    Background: For many years, studies have shown that the results of clinical trials are often published or reported selectively with a statistically significant bias in favour of positive trial results. Trial registration as a precondition for publication had only limited effects on current practice. Results of trials which were approved by research ethics committees are often published only partially, with a substantial time lag or not at all. This study examined existing procedures of RECs in the European Union to monitor (...)
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  17.  14
    Collective Agency and the Concept of ‘Public’ in Public Involvement: A Practice-Oriented Analysis.Tobias Hainz, Sabine Bossert & Daniel Strech - 2016 - BMC Medical Ethics 17 (1):1-14.
    BackgroundPublic involvement activities are promoted as measures for ensuring good governance in challenging fields, such as biomedical research and innovation. Proponents of public involvement activities include individual researchers as well as non-governmental and governmental organizations. However, the concept of ‘public’ in public involvement deserves more attention by researchers because it is not purely theoretical: it has important practical functions in the guidance, evaluation and translation of public involvement activities.DiscussionThis article focuses on collective agency as one property a public as a (...)
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  18.  22
    Ethics in Public Health and Health Policy.Daniel Strech, Irene Hirschberg & Georg Marckmann (eds.) - 2013 - Springer.
    Faden, R. & Shebaya, S, Public Health Ethics. The Stanford Encyclopedia of Philosophy (Summer 2010 Edition), Edward N. Zalta (ed.). Available from: htt : lato.stanford.edu archives sum2010 entries ublichealth-ethics (accessed ...
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  19.  20
    Did We Describe What You Meant? Findings and Methodological Discussion of an Empirical Validation Study for a Systematic Review of Reasons.Marcel Mertz, Neema Sofaer & Daniel Strech - 2014 - BMC Medical Ethics 15 (1):69.
    The systematic review of reasons is a new way to obtain comprehensive information about specific ethical topics. One such review was carried out for the question of why post-trial access to trial drugs should or need not be provided. The objective of this study was to empirically validate this review using an author check method. The article also reports on methodological challenges faced by our study.
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  20.  20
    How to Evaluate Conflict of Interest Policies.Daniel Strech & Hannes Knüppel - 2011 - American Journal of Bioethics 11 (1):37 - 39.
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  21.  23
    BMBF-Klausurwoche: Clinical Ethics Consultation: Theories & Methods–Implementation–Evaluation.Laszlo Kovacs & Daniel Strech - 2008 - Ethik in der Medizin 20 (2):148-150.
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  22.  15
    Report on the Conference “Clinical Ethics Consultation: Theories and Methods—Implementation—Evaluation,” February 11–15, 2008, Bochum, Germany. [REVIEW]Daniel Strech, Ana Borovečki & László Kovács - 2009 - Medicine, Health Care and Philosophy 12 (1):109-110.
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  23.  8
    Qualität Und Ethik – Beiträge Zur Guten Gesundheitsversorgung.Gerald Neitzke & Daniel Strech - 2017 - Ethik in der Medizin 29 (3):183-185.
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  24.  14
    Research Guideline Recommendations for Broad Consent Forms in Biobank Research and How They Are Currently Addressed in Practice.Daniel Strech, Hannes Kahrass & Irene Hirschberg - 2015 - American Journal of Bioethics 15 (9):60-63.
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  25.  6
    Kommentar I zum Fall: „Der Patientenwille als oberste Instanz – schwierige Umsetzung in der klinischen Forschung“.Holger Langhof & Daniel Strech - 2016 - Ethik in der Medizin 28 (2):153-155.
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  26.  12
    Which Public to Involve? More Reflection on Collective Agency and Sufficient Representativeness Is Needed.Tobias Hainz & Daniel Strech - 2014 - American Journal of Bioethics 14 (6):31-33.
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  27.  9
    BMBF-Klausurwoche: Clinical Ethics Consultation: Theories & Methods – Implementation – Evaluation. [REVIEW]Laszlo Kovacs & Daniel Strech - 2008 - Ethik in der Medizin 20 (2):148-150.
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  28. Ethics and Governance of Biomedical Research: Theory and Practice.Daniel Strech & Marcel Mertz (eds.) - 2016 - Springer.
     
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  29. The Ethics of a Restrictive Regulation of Trial Registration.Daniel Strech - 2011 - Ethik in der Medizin 23 (3):177-189.
     
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