The case of Semmelweis has been well known since Hempel. More recently, it has been revived by Peter Lipton, Donald Gillies, Alexander Bird, Alex Broadbent, and Raphael Scholl. While these accounts differ on what exactly the case of Semmelweis shows, they all agree that Semmelweis was an excellent reasoner. This widespread agreement has also given rise to a puzzle: why Semmelweis’s views were rejected for so long. I aim to dissolve both this puzzle and the standard view of Semmelweis by (...) showing that, contrary to prevailing opinion, Semmelweis was not the excellent reasoner he has been assumed to be. (shrink)

In this paper, I argue (i) that there are certain methodological practices that are epistemically significant, and (ii) that we can test for the success of these practices empirically by examining case-studies in the history of science. Analysing a particular episode from the history of medicine, I explain how this can help us resolve specific cases of underdetermination. I conclude that, while the anti-realist is (more or less legitimately) able to construct underdetermination scenarios on a case-by-case basis, he will have (...) to abandon the strategy of using algorithms to do so, thus losing the much needed guarantee that there will always be rival cases of the required kind. (shrink)

One typical realist response to the argument from underdetermination of theories by evidence is an appeal to epistemic criteria besides the empirical evidence to argue that, while scientific theories might be empirically equivalent, they are not epistemically equivalent. In this article, I spell out a new and reformulated version of the underdetermination argument that takes such criteria into account. I explain the notion of epistemic equivalence which this new argument appeals to, and argue that epistemic equivalence can be achieved in (...) several, significantly different, ways. On the basis of this ‘multiple realisability’ of epistemic equivalence, I then proceed to explain and examine some of the main consequences of this reformulated underdetermination argument for both realists and anti-realists. (shrink)

It has recently been suggested that realist responses to historical cases featured in pessimistic meta-inductions are not as successful as previously thought. In response, selective realists have updated the basic divide et impera strategy specifically to take such cases into account and to argue that more modern realist accounts are immune to the historical challenge. Using a case study—that of the nineteenth-century zymotic theory of disease—I argue that these updated proposals fail and that even the most sophisticated recent realist accounts (...) remain vulnerable to the challenge from history. (shrink)

This chapter relocates the debate about the theoretical virtues to the empirical level and argues that the question of whether the virtues (and what virtues, if any) have epistemic import is best answered empirically, through an examination of actual scientific theories and hypotheses in the history of science. As a concrete example of this approach, the chapter discusses a case study from the mid-nineteenth-century debate about the transmissibility of puerperal fever. It argues that this case shows that the virtues are (...) at least sometimes epistemic, but also that neither scientific realists nor anti-realists get it quite right: the virtues, even if epistemic, are not necessarily truth-conducive, but neither are they merely pragmatic. It also argues that the discussion of puerperal fever shows that the virtue question, as it is currently featured in the scientific realism debate, ought to be reformulated. We should examine not just whether a given scientific theory has virtues or not, but rather how debates among competing theories, all of which have some virtues, get resolved. (shrink)

In the mid-1800s, there was much debate about the origin or 'exciting cause' of cholera. Despite much confusion surrounding the disease, the so-called miasma theory emerged as the prevalent account about cholera's cause. Going against this mainstream view, the British physician John Snow inferred several things about cholera's origin and pathology that no one else inferred. Without observing the vibrio cholerae, however,-data unavailable to Snow and his colleagues-, there was no way of settling the question of what exactly was causing (...) cholera and how, or if, it was passed on. The question then arises as to how Snow arrived at conclusions so systematically different from those of his opponents. In this paper, I want to look at Snow's reasoning in some detail, and show that there were certain principles, explanatory power in particular, that were epistemologically important to Snow in their own right. I will show that Snow himself takes explanatory power to be an epistemic property, and makes explicit links between explanatory power and confirmation. Systematically juxtaposing Snow's claims and his opponents', I will show that Snow was right to tout the explanatory power of his theory, and that his conclusions about the epistemic superiority of his theory over that of the miasmatists' were justified. (shrink)

The main purpose of this paper is to test structural realism against (one example from) the historical record. I begin by laying out an existing challenge to structural realism -- that of providing an example of a theory exhibiting successful structures that were abandoned -- and show that this challenge can be met by the miasma theory of disease. However, rather than concluding that this is an outright counterexample to structural realism, I use this case to show why it is (...) that structural realism, in its current form, has trouble dealing with theories outside physics. I end by making some concrete suggestions for structural realists to pursue if, indeed, they are serious about extending structural realism to other domains. (shrink)

One premise of the underdetermination argument is that entailment of evidence is the only epistemic constraint on theory-choice. I argue that methodological rules can be epistemically significant, both with respect to observables and unobservables. Using an example from the history of medicine—Koch’s 1882 discovery of tuberculosis bacteria—I argue that even anti-realists ought to accept that these rules can break the tie between theories that are allegedly underdetermined. I then distinguish two types of underdetermination and argue that anti-realists, in order to (...) maintain the underdetermination argument, need to do more than show that theories are empirically equivalent: they need to show that a certain kind of underdetermination obtains. (shrink)

I argue that neither realist nor anti-realist accounts of theory-change can account for the transition from zymotic views of disease to germ views. The trouble with realism is its focus on stable and continuous elements that get retained in the transition from one theory to the next; the trouble with anti-realism is its focus on the radical discontinuity between theories and their successors. I show that neither of these approaches works for the transition from zymes to germs: there is neither (...) continuity nor discontinuity, but, instead, a gradual evolution from zyme to germ views, during which germ elements are slowly incorporated into zymotic views until, eventually, none of the original zymotic constituents are left. I argue that the problem with both realism and anti-realism is that they rest on the unwarranted assumption that there are clearly delineated zymotic and germ theories as well as arguments for and against these theories, an assumption that does not hold. (shrink)

The case of John Snow has long been important to epidemiologists and public health officials. However, despite the fact that there have been many discussions about the various aspects of Snow’s case, there has been virtually no discussion about what guided Snow’s reasoning in his coming to believe his various conclusions about cholera. Here, I want to take up this question in some detail and show that there are a number of specific principles of reasoning that played a crucial role (...) for Snow. Moreover, these principles were episte- mologically important to Snow, a fact about which Snow is explicit in many places. An analysis of Snow’s case suggests that, because of the epistemic role such principles of reasoning can play, health care practitioners ought to understand their practices to be theoretically informed in these ways, and not just data driven. (shrink)

This document collects discussion and commentary on issues raised in the workshop by its participants. Contributors are: Greg Frost-Arnold, David Harker, P. D. Magnus, John Manchak, John D. Norton, J. Brian Pitts, Kyle Stanford, Dana Tulodziecki.

My purpose in this paper is to show how a re-examination of Snow’s famous South London water study, widely taken to have established that cholera is water-borne, highlights some problems with current, scientific realist accounts of theory-change. When examining scientific controversies, such accounts focus disproportionately on the ‘winning’ theories and their properties, or on those of the reasoning of the scientists who proposed them. I argue that this focus is misguided and leads us to neglect much of what is epistemically (...) valuable in episodes of theory-change, thereby leading to inaccurate views about both the dynamics of theory-change and the notion of scientific progress that accompanies it. I end by sketching some implications for the philosophy of epidemiology. (shrink)

In this paper, I examine the transition from zymotic views of disease to germ views in Britain in the mid-1800s. I argue that neither realist nor anti-realist accounts of theory-change can account for this case, because both rely on a well-defined notion of theory, which, as the paper will show, is inapplicable in this instance. After outlining the zymotic theory of disease, I show that, even though it hardly had anything in common with the germ theory, it was highly successful. (...) However, despite this success, it is not possible to identify stable elements that were carried over to the germ theory; thus, realists cannot account for the shift from one to the other. Anti-realists, however, don’t do much better: their focus tends to be on (radical) discontinuities across theories, yet the zymotic case does not exemplify this, either. Instead, there is a slow and complex evolution from zymotic to germ views, during which various zymotic elements are assimilated into the germ theory, until, eventually, none of the zymotic theory’s original elements are left. (shrink)

My talk will be guided by the idea that there are some familiar scientific practices that are epistemically significant. I will argue that we can test for the success of these practices empirically by examining cases in the history of science. Specifically, I will reconstruct one particular episode in the history of medicine – John Snow's reasoning concerning the infectiousness of cholera – and offer this case as a concrete example of the sort of empirical research that needs to be (...) done in order to discover what kinds of methodological practices and rules are actually of epistemic interest. Analysing this case, I will explain how it (and other cases like it) can help us resolve specific cases of underdetermination. After exploring some possible anti-realist responses to this argument, I will conclude that, while the anti-realist is (more or less legitimately) able to construct underdetermination scenarios on a case-by-case basis, he will likely have to abandon the strategy of using algorithms to do so, thus losing the much needed guarantee that there will always be rival cases of the required kind. (shrink)