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Danielle M. Wenner
Carnegie Mellon University
  1.  28
    The Social Value Requirement in Research: From the Transactional to the Basic Structure Model of Stakeholder Obligations.Danielle M. Wenner - 2018 - Hastings Center Report 48 (6):25-32.
    It has long been taken for granted that clinical research involving human subjects is ethical only if it holds out the prospect of producing socially valuable knowledge. Recently, this social value requirement has come under scrutiny, with prominent ethicists arguing that the social value requirement cannot be substantiated as an ethical limit on clinical research, and others attempting to offer new support. In this paper, I argue that both criticisms and existing defenses of the social value requirement are predicated on (...)
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  2.  22
    The Social Value of Knowledge and the Responsiveness Requirement for International Research.Danielle M. Wenner - 2017 - Bioethics 31 (2):97-104.
    Ethicists have long recognized that two necessary features of ethical research are scientific validity and social value. Yet despite a significant literature surrounding the validity component of this dictate, until recently there has been little attention paid to unpacking what the social value component might require. This article introduces a framework for assessing the social value of research, and in particular, for determining whether a given research program is likely to have significant social value of the kind necessary to fulfill (...)
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  3.  21
    The Social Value of Knowledge and International Clinical Research.Danielle M. Wenner - 2015 - Developing World Bioethics 15 (2):76-84.
    In light of the growth in the conduct of international clinical research in developing populations, this paper seeks to explore what is owed to developing world communities who host international clinical research. Although existing paradigms for assigning and assessing benefits to host communities offer valuable insight, I criticize their failure to distinguish between those benefits which can justify the conduct of research in a developing world setting and those which cannot. I argue that the justification for human subjects research is (...)
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  4. Patient-Funded Trials: Opportunity or Liability?Danielle M. Wenner, Alex John London & Jonathan Kimmelman - 2015 - Cell Stem Cell 17 (2):135-137.
    Patient-funded trials are gaining traction as a means of accelerating clinical translation. However, such trials sidestep mechanisms that promote rigor, relevance, efficiency, and fairness. We recommend that funding bodies or research institutions establish mechanisms for merit review of patient-funded trials, and we offer some basic criteria for evaluating PFT protocols.
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  5. Against Permitted Exploitation in Developing World Research Agreements.Danielle M. Wenner - 2016 - Developing World Bioethics 16 (1):36-44.
    This paper examines the moral force of exploitation in developing world research agreements. Taking for granted that some clinical research which is conducted in the developing world but funded by developed world sponsors is exploitative, it asks whether a third party would be morally justified in enforcing limits on research agreements in order to ensure more fair and less exploitative outcomes. This question is particularly relevant when such exploitative transactions are entered into voluntarily by all relevant parties, and both research (...)
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  6.  8
    Nondomination and the Limits of Relational Autonomy.Danielle M. Wenner - 2020 - International Journal of Feminist Approaches to Bioethics 13 (2):28-48.
    Feminist theorists worry that liberal conceptions of autonomy are predicated on a problematic view of the individual as entirely self-sufficient and independent of her relationships with others. On one hand, they point out, agency cannot be separated from interdependence. Large swaths of our lives, especially during formative years, are spent dependent on others, and those relationships inform our preferences, our values, and our understandings of our selves. On the other hand, feminist theorists assert, although some kinds of relationships enhance our (...)
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  7.  49
    Puberty-Blocking Treatment and the Rights of Bad Candidates.B. R. George & Danielle M. Wenner - 2019 - American Journal of Bioethics 19 (2):80-82.
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  8. Conflicts Among Multinational Ethical and Scientific Standards for Clinical Trials of Therapeutic Interventions.Jacob M. Kolman, Nelda P. Wray, Carol M. Ashton, Danielle M. Wenner, Anna F. Jarman & Baruch A. Brody - 2012 - Journal of Law, Medicine and Ethics 40 (1):99-121.
    There has been a growing concern over establishing norms that ensure the ethically acceptable and scientifically sound conduct of clinical trials. Among the leading norms internationally are the World Medical Association's Declaration of Helsinki, guidelines by the Council for International Organizations of Medical Sciences, the International Conference on Harmonization's standards for industry, and the CONSORT group's reporting norms, in addition to the influential U.S. Federal Common Rule, Food and Drug Administration's body of regulations, and information sheets by the Department of (...)
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  9.  3
    Licensing Domination: Foreign Will and Social Benefit.Danielle M. Wenner - 2019 - American Journal of Bioethics 19 (9):60-62.
    Volume 19, Issue 9, September 2019, Page 60-62.
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  10.  12
    Exploitation and International Clinical Research: The Disconnect Between Goals and Policy.Danielle M. Wenner - 2018 - In David Boonin (ed.), The Palgrave Handbook of Philosophy and Public Policy. Cham, Switzerland: Springer Verlag. pp. 563-574.
    A growing proportion of clinical research funded by pharmaceutical companies, high-income country research agencies, and not-for-profit funders is conducted in low- and middle-income settings. Disparities in wealth and access to healthcare between the populations where new interventions are often tested and those where many of them are ultimately marketed raise concerns about exploitation. This chapter examines several ethical requirements frequently advanced as mechanisms for protecting research subjects in underserved communities from exploitation and evaluates the effectiveness of those mechanisms as responses (...)
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  11.  22
    The Need for Non-Ideal Theory: A Case Study in Deliberative Democracy.Danielle M. Wenner - 2017 - In M. Weber & Kevin Vallier (eds.), Political Utopias: Contemporary Debates. Oxford, UK: pp. 203-231.
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  12.  22
    Discharging the Duty to Conduct International Clinical Research.Danielle M. Wenner - 2012 - American Journal of Bioethics 12 (11):44-46.
  13.  7
    Do Surgical Trials Meet the Scientific Standards for Clinical Trials.Danielle M. Wenner, Baruch A. Brody, Anna Jarman, Jacob M. Kolman, Nelda Wray & Carol Ashton - 2012 - Journal of the American College of Surgeons 215 (5):722-730.
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  14.  2
    Trials and Tribulations: The Professional Development of Surgical Trialists.Danielle M. Wenner, Anna Jarman, Nelda Wray & Carol Ashton - 2012 - American Journal of Surgery 204 (3):339-346.
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  15.  8
    Incorporating Health Equity Into COVID-19 Reopening Plans: Policy Experimentation in California.Emily A. Largent, Govind Persad, Michelle M. Mello, Danielle M. Wenner, Daniel B. Kramer, Brownsyne Tucker Edmonds & Monica Peek - 2021 - American Journal of Public Health 1 (1):e1-e8.
    California has focused on health equity in the state’s COVID-19 reopening plan. The Blueprint for a Safer Economy assigns each of California’s 58 counties into 1 of 4 tiers based on 2 metrics: test positivity rate and adjusted case rate. To advance to the next less-restrictive tier, counties must meet that tier’s test positivity and adjusted case rate thresholds. In addition, counties must have a plan for targeted investments within disadvantaged communities, and counties with more than 106 000 residents must (...)
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  16. Diversion Effects, Incentive Effects, and the Goals of Research Ethics Promulgations.Danielle M. Wenner - 2015 - Journal of Law and the Biosciences.
  17.  16
    Danielle M. Wenner Replies.Danielle M. Wenner - 2019 - Hastings Center Report 49 (2):47-47.
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  18.  10
    Henk ten Have: Global Bioethics: An Introduction: New York, Routledge, 2016, 312 Pp, $53.95. [REVIEW]Danielle M. Wenner - 2016 - Monash Bioethics Review 34 (2):152-155.
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  19.  8
    Not Just a Tragic Compromise: The Positive Case for Adolescent Access to Puberty-Blocking Treatment.Danielle M. Wenner & B. R. George - 2021 - Bioethics 35 (9):925-931.
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  20.  2
    Not Just a Tragic Compromise: The Positive Case for Adolescent Access to Puberty‐Blocking Treatment.Danielle M. Wenner & B. R. George - forthcoming - Wiley: Bioethics.
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