Based on brain imaging findings, we present a model according to which addiction emerges as an imbalance in the information processing and integration among various brain circuits and functions. The dysfunctions reflect (a) decreased sensitivity of reward circuits, (b) enhanced sensitivity of memory circuits to conditioned expectations to drugs and drug cues, stress reactivity, and (c) negative mood, and a weakened control circuit. Although initial experimentation with a drug of abuse is largely a voluntary behavior, continued drug use can eventually (...) impair neuronal circuits in the brain that are involved in free will, turning drug use into an automatic compulsive behavior. The ability of addictive drugs to co‐opt neurotransmitter signals between neurons (including dopamine, glutamate, and GABA) modifies the function of different neuronal circuits, which begin to falter at different stages of an addiction trajectory. Upon exposure to the drug, drug cues or stress this results in unrestrained hyperactivation of the motivation/drive circuit that results in the compulsive drug intake that characterizes addiction. (shrink)

Using an original approach, Mauro Dardo recounts the major achievements of twentieth-century physics--including relativity, quantum mechanics, atomic and nuclear physics, the invention of the transistor and the laser, superconductivity, binary pulsars, and the Bose-Einstein condensate--as each emerged. His year-by-year chronicle, biographies and revealing personal anecdotes help bring to life the main events since the first Nobel Prize was awarded in 1901. The work of the most famous physicists of the twentieth century--including the Curies, Bohr, Heisenberg, Einstein, Fermi, Feynman, Gell-Mann, (...) Rutherford, and Schrödinger--is presented, often in the words and imagery of the prize-winners themselves. Mauro Dardo is Professor of Experimental Physics at Amedeo Avogadro University. He has served as Dean of the new Faculty of Sciences at the University of Turin in Alessandria, Piedmont, and has also served as Director of the university's new department of Sciences and Advanced Technologies. (shrink)

Lucas Swaine’s liberalism of conscience is at risk of failing to respect justificatory requirements of political liberalism. His theory ought to be further distinguished from the views of John Locke and John Rawls, respectively, and should be extended to engage extreme secularists as well as theocrats.

Además de considerar a la metafísica como una “rama de la literatura fantástica”, Borges fue desarrollando su propia filosofía a lo largo de sus ensayos, sus poemas y sus cuentos. Y lo hizo discretamente, atribuyéndoles sus tesis a otros autores. Jaime Rest habló alguna vez del nominalismo del escritor argentino, pero en este nominalismo Borges introdujo una orientación hermenéutica y semiótica que lo emparenta con dos de sus contemporáneos: Martin Heidegger y Claude Lévi-Strauss.

John Tomasi's Free Market Fairness treats both traditions with depth, nuance, and unremitting fair-mindedness, and then points us toward a synthesis. Social democrats and libertarians equally need to read this book.

This Chapter aims to present a very preliminary exploration of the role and functioning of some ‘leading ideas’ that represent the most consistent attempts to balance freedom of scientific research with the need to protect participants and the community as a whole. To this end, we searched two databases, a scientific and a legal one, for some keywords (Freedom of research, Precautionary principle, Risk-based approach, Responsible research and innovation), to check the consistency of their presence and evolution over time. Without (...) aiming to in-depth investigate the precise connotations of each term and the context in which they are used from time to time, the core idea is to provide a very first quantitative exploration, which lays the foundations for further future investigation. (shrink)

"This is a daring, inventive, and engagingly written book. Tomasi escapes the current liberal fixation with justice and legitimacy by asking searching questions about how truly good lives can be led under a just liberal regime.

Research Articles John Tomasi, Social Philosophy and Policy, FirstView Article.

Heidegger, Winner, and Ellul's critiques of Western technology focus on a notion of efficiency that subordinates to itself all non-instrumental values. An alternative conception of efficiency is proposed based on the Taoist theory of non-action. The ancient Taoist text, The Chuang Tzu, reveals a type of efficiency that is effective, resourceful, and entrepreneurial. It is a form of action which has an intimate rather than alienated relation to technology, and which is sensitive to the ethical and aesthetic values that Heidegger (...) and Ellul claim are excluded from the Western conception of efficiency. (shrink)

We live in an age when the dominant technologically utilitarian worldview is undergoing a transformation. To increase our awareness of this change, Turning Toward Technology introduces readers to the possibility of an alternative technological worldview by examining foundational concepts to Asian thought. The early Eastern philosophical treatment of technology was not ethical, but ontological, exhibiting sensitivity to how human existence was defined and determined in its relation to technology and to reality as a whole. Within the Eastern cultural orientation, technological (...) development was guided by a singular aesthetic sensibility to the useful, the good, the beautiful, the true, and the holy. Instead of controlling the shape of future technology by systems of rational management, George Teschner and Alessandro Tomasi recommend a view of technology that arises from questioning fundamental assumptions within Western culture about knowledge, reality, and human nature. Turning Toward Technology aims to stimulate awareness of an alternative technological paradigm, and thus a different mode of social action that can establish an optimistic future for global civilization. (shrink)

In his writings Wittgenstein has touched upon some key aspects of aesthetic experience, of the experience of art, and of the dynamics of culture. Moreover, several lines of research in these fields have emerged and are still emerging from the roots of Wittgenstein's thought. This volume collects a number of essays on these topics by renowned international scholars (such as H.-J. Glock, J. Hyman, S. Majetschak, J. Schulte, A. Voltolini, and W. Vossenkuhl) and younger researchers. Our aim is to document (...) the presence of aesthetics across the development of Wittgenstein's thought and to present Wittgenstein's point of view, as well as new views inspired by Wittgenstein, on music, literature and poetry, the visual arts, and architecture. (shrink)

ABSTRACTThe ten essays in this symposium offer a rich and varied set of challenges to the market-democratic research program. Rather than replying to each critic in turn, I respond only to the main lines of critical challenge raised in this collection: that my account of thick economic liberty is too vague, that economic liberties are not basic, that market democracy gives too little attention to socialist possibilities, that market democracy can accommodate only an impoverished conception of fair equality of opportunity, (...) and, most notably, that market democracy is grounded upon a tendentious or “bourgeois” conception of the person. To meet these criticisms, I refine a central claim of market democracy: that the right to private ownership of productive property is a basic right. In response to the worry that market democracy allows for class domination, I revise market democracy on the issue of bequests. After replying to the critics I extend my challenge to social democracy, presenting an historical argument against liberal democratic socialism. (shrink)

Heidegger, Winner, and Ellul's critiques of Western technology focus on a notion of efficiency that subordinates to itself all non-instrumental values. An alternative conception of efficiency is proposed based on the Taoist theory of non-action (wu-wei). The ancient Taoist text, The Chuang Tzu, reveals a type of efficiency that is effective, resourceful, and entrepreneurial. It is a form of action which has an intimate rather than alienated relation to technology, and which is sensitive to the ethical and aesthetic values that (...) Heidegger and Ellul claim are excluded from the Western conception of efficiency. (shrink)

The COVID-19 pandemic was a global health crisis that required US residents to understand the phenomenon, interpret the cues, and make sense within their environment. Therefore, how the communication of COVID-19 was framed to stakeholders during the early stages of the pandemic became important to guide them through specific actions in their state and subsequently with the sensemaking process. The present study examines which frames were emphasized in the states' press releases on policies and other COVID information to influence stakeholders (...) on what to focus on to help with sensemaking during the crisis. We conducted content analysis on 602 press releases from 50 US states using an unsupervised machine learning approach called Latent Dirichlet Allocation (LDA). The results show that health communication using press releases to help the public make sense of the crisis were framed to include health frames as well as economic frames. Health communication messages are typically framed with health and safety measures; however, this study shows that economic frames were emphasized more than public health frames in the government's health communication for COVID-19, which forced both large and small businesses to engage in specific socially responsible activities that were previously voluntary to support public health safety. (shrink)

Gottlob Frege criticized Kant's use of the term "representation" in a footnote in the Foundations of Arithmetics. According to Frege, Kant used the term "representation" for mental images, which are private and incommunicable, and also for objects and concepts. Kant thereby gave "a strongly subjectivistic and idealistic coloring" to his thought. The paper argues that Kant avoided the kind of subjectivism and idealism which Frege hints in his remark. For Kant, having "Vorstellungen" requires the capacity of synthesis, by virtue of (...) which the mind goes beyond its subjective states, and its modifications become presentations of an independent world. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:PLATO'S STATESMAN STORY: THE BIRTH OF FICTION RECONCEIVED by John Tomasi In "Plato's Atlantis Story and the Birth of Fiction," Christopher Gill wants to distinguish the story ofAdantis in the Critias from Plato's earlier stories—like diat in the Statesman.1 These stories, Gill claims, belong to different literary genres. While the Statesman story is but another example of fable, the Adantis story of the Critias represents the first example—the (...) first in Plato and indeed the earliest in all Western written culture—of an exciting new literary genre: narrative fiction. Gill describes narrative fiction as a kind ofgame into which the author invites his audience to join. The invitation to play the game of fiction is an invitation "to share in the willing and conscious acceptance of the false as true" (p. 65). The audience is provided the opportunity to become "willfully self-deceived" about the story's truth. Perhaps the main constraint on a story's belonging to the genre of fiction is the author's ability to transmit this special invitation to his reader. Gill says one major way to do this is by a framework of introductory signals which are mixed in a certain way. The Adantis story, as Gill claims, seems to be framed with signals that a self-deception game is about to begin. Socrates says Critias is like a playwright competing in front of an audience (108a). Gill reads line 107 to mean that Critias is concerned direcdy with "the problem of giving his narrative the illusory realism which he says audiences require." Also, Gill says, "the fact that it is a game is signalled by the overt claim to historical truth in a context in which we are not disposed to accept the claim" (p. 72). Plato thus introduces the Adantis story with a delicate mixture ofconflictingclaims about the story's factual status. Gill suggests the reader should interpret this special mixture of signals as being a Philosophy and Literature, © 1990, 14: 348-358 John Tomasi349 sort of invitation to "make pretend," to play a pleasant game, to allow die reader to become willfully self-deceived. Within die Adantis story itself diere are further marks of die fiction genre. Narrative fiction can be a compelling game, and good fiction writers often slip into the game themselves, writing with a concern for detail and with a word choice so sensitive that the reader may feel that die writer too must believe in this fictional world. The Adantis story certainly exhibits this mark of fiction. As Gill puts it, in writing about Adantis Plato seems at times to have become "momentarily infatuated with the world he is creating."2 Such infatuation, exhibited especially perhaps in the detailed descriptions in the Critias of the splendors of the Adantean city and in the passionate portrayal of the growth of hubris in the citizens' hearts, is perhaps what gives the Adantis story some of its special potency, what makes it especially gripping to us (116c—ll7e; 121a-c). Clearly, it is a story with which writer as well as reader might develop an intimate relationship. In Plato's Atlantis story the framing signals are mixed with a deliberate subtlety, and the reader at times senses the writer's infatuation with his own tale. The Adantis story is thus crafted to get from the reader what Plato is after: "a willed self-deception, a chosen suspension ofincredulity for the duration of the story." Gill concludes, "This new element of intended complicity in the fictional game makes his work the first piece of deliberately fictional narrative in Greek literature" (p. 76). Gill's argumentthat the Adantis story belongs to the genre ofnarrative fiction is provocative and on the whole convincing. But is the Adantis story really the first Western instance of that genre? Is it even Plato's first attempt at fiction? I think it is not. I would like now to examine the storywithin the Statesman, a storywhich Gill says was probablywritten before the Adantis story. Might the Statesman story be a still earlier instance of narrative fiction? The signals framing the Statesman story are mixed indeed. At first, the Stranger tells young Socrates that... (shrink)