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  1.  37
    Principles of Early Stopping of Randomized Trials for Efficacy: A Critique of Equipoise and an Alternative Nonexploitation Ethical Framework.David Buchanan & Franklin G. Miller - 2005 - Kennedy Institute of Ethics Journal 15 (2):161-178.
    : Recent controversial decisions to terminate several large clinical trials have called attention to the need for developing a sound ethical framework to determine when trials should be stopped in light of emerging efficacy data. Currently, the fundamental rationale for stopping trials early is based on the principle that equipoise has been disturbed. We present an analysis of the ethical and practical problems with the "equipoise disturbed" position and describe an alternative ethical framework based on the principle of nonexploitation. This (...)
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  2.  4
    Perceived Benefits and Harms of Involuntary Civil Commitment for Opioid Use Disorder.Elizabeth A. Evans, Calla Harrington, Robert Roose, Susan Lemere & David Buchanan - 2020 - Journal of Law, Medicine and Ethics 48 (4):718-734.
    Involuntary civil commitment to treatment for opioid use disorder prevents imminent overdose, but also restricts autonomy and raises other ethical concerns. Using the Kass Public Health Ethics Framework, we identified ICC benefits and harms. Benefits include: protection of vulnerable, underserved patients; reduced legal consequences; resources for families; and “on-demand” treatment access. Harms include: stigmatizing and punitive experiences; heightened family conflict and social isolation; eroded patient self-determination; limited or no provision of OUD medications; and long-term overdose risk. To use ICC ethically, (...)
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  3.  6
    [Book Review] an Ethic for Health Promotion, Rethinking the Sources of Human Well-Being. [REVIEW]David Ross Buchanan - 2001 - Hastings Center Report 31 (1):43-45.
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  4.  9
    Children’s Developing Understanding of the Relation Between Variable Causal Efficacy and Mechanistic Complexity.Christopher D. Erb, David W. Buchanan & David M. Sobel - 2013 - Cognition 129 (3):494-500.
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  5.  35
    Promoting Justice and Autonomy in Public Policies to Reduce the Health Consequences of Obesity.David R. Buchanan - 2015 - Kennedy Institute of Ethics Journal 25 (4):395-417.
    Public policies to reduce the extent of obesity in the United States have generated considerable public controversy. The paper examines the implications of proposed policies for the principles of justice and autonomy and key assumptions underlying the major contending positions with respect to the relative weight that should be assigned to them in balancing their respective claims. The analysis traces the crux of the debate regarding the ethical warrant for policies to restrict access to calorie-dense foodstuffs to two key issues: (...)
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  6. Ethical Issues in Cancer Chemoprevention Trials: Considerations for IRBs and Investigators.Julia Slutsman, David Buchanan & Christine Grady - 2007 - IRB: Ethics & Human Research 29 (2):1-6.
    Cancer chemoprevention trials test the efficacy of pharmaceutical agents in preventing cancer in at-risk research subjects who are neither patients diagnosed with the disease nor typical healthy volunteers. Such trials present unique challenges to investigators and IRB reviewers when evaluating risks and benefits, assessing informed consent, and compensating subjects. Investigators and IRBs should pay particular attention to the criteria used to define at-risk subjects and carefully assess the strength of the evidence supporting them, as this is critical to evaluating the (...)
     
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  7.  94
    Signification and Pain: A Semiotic Reading of Fibromyalgia.John Quintner, David Buchanan, Milton Cohen & Andrew Taylor - 2003 - Theoretical Medicine and Bioethics 24 (4):345-354.
    Patients with persistent pain who lack adetectable underlying disease challenge thetheories supporting much of biomedicalbody-mind discourse. In this context,diagnostic labeling is as inherently vulnerableto the same pitfalls of uncertainty that besetany other interpretative endeavour. The endpoint is often no more than a name ratherthan the discovered essence of a pre-existentmedical condition. In 1990 a Committee of theAmerican College of Rheumatology (ACR)formulated the construct of Fibromyalgia in anattempt to rectify a situation of diagnosticconfusion faced by patients presenting withwidespread pain. It was (...)
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  8.  27
    The Austerity Bargain and the Social Self: Conceptual Clarity Surrounding Health Cutbacks.David A. Buchanan - 2013 - Nursing Philosophy 14 (1):38-44.
    As necessary austerity measures make major inroads into western health services, this paper investigates the philology of austerity and finds that there are two subtly similar yet importantly different derivations from the Latin and the Greek. The Latin austerus is an abstract term meaning dry, harsh, sour; whereas the Greek austeros has a more embodied and literal meaning of making the tongue dry. What seems an initially subtle difference between the metaphorical and the metonymic plays out as involving seriously different (...)
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  9.  8
    The Ethics and Efficacy of Behavior Change ResearchAn Ethic for Health Promotion. [REVIEW]Mildred Z. Solomon & David R. Buchanan - 2001 - Hastings Center Report 31 (1):43.
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  10. Bridging the Gap: Children's Developing Inferences About Objects' Labels and Insides From Causality-at-a-Distance.David W. Buchanan & David M. Sobel - 2008 - In B. C. Love, K. McRae & V. M. Sloutsky (eds.), Proceedings of the 30th Annual Conference of the Cognitive Science Society. Cognitive Science Society. pp. 64--70.
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