Clinical trials of xenotransplantation may begin early in the next decade, with kidneys from genetically modified pigs transplanted into adult humans. If successful, transplanting pig hearts into children with advanced heart failure may be the next step. Typically, clinical trials have a specified end date, and participants are aware of the amount of time they will be in the study. This is not so with XTx. The current ethical consensus is that XTx recipients must consent to lifelong monitoring. While this (...) presents challenges to the right to withdraw in the adult population, additional and unanswered questions also linger in the paediatric population. In paediatric XTx, parents or guardians consent not only to the initial treatment of the child but also to lifelong monitoring, thus making a decision whose consequences will remain present as the child develops the capacity for assent, and finally the capacity for informed consent or refusal. This article presents and evaluates unanswered paediatric ethical questions in regard to the right to withdraw from XTx follow-up in the paediatric population. (shrink)
Death in the Clinic fills a gap in contemporary medical education by explicitly addressing the concrete clinical realities about death with which practitioners, patients, and their families continue to wrestle. Visit our website for sample chapters!
In Neutrality and the Academic Ethic, distinguished philosopher Robert L. Simon explores the claim that universities can and should be politically neutral. He examines conceptual questions about the meaning of neutrality, distinguishes different conceptions of what neutrality involves, and considers in what sense, if any, institutional neutrality is both possible and desirable. In Part II, a collection of original and previously published essays provides different views on these and related issues.
This article examines a particular debate between Eamonn Callan and William Galston concerning the need for a civic education which counters the divisive pull of pluralism by uniting the citizenry in patriotic allegiance to a single national identity. The article offers a preliminary understanding of nationalism and patriotism before setting out the terms of the debate. It then critically evaluates the central idea of Callan that one might be under an obligation morally to improve one''s own patriotic inheritance, pointing to (...) the ineliminable tension between the valuation of one''s own patria by its own terms and a detached critical reason. It concludes by suggesting that we are, in advance of our education, members of a particular patria and that any education must be particularistic. Finally, the danger is noted of presuming that, in each case, there is a single, determinate national tradition. (shrink)
In Altered Sensations: Rudolph Koenig’s Acoustical Workshop in Nineteenth-Century Paris, David Pantalony achieves the difficult goal of balancing technical detail and historical narrative in his account of Rudolph Koenig and the nineteenth-century Parisian scientific instrument trade. The Parisian instrument making trade, particularly that of acoustical instruments, was at a high point in the mid-nineteenth century. Chief among scientific instrument makers was Rudolph Koenig (1832-1901), whose atelier at 30 Hautefeuille was at once an artisanal studio, a laboratory, a workshop (...) and a showroom. The negotiations necessary for one building, and one person, to channel such different activities is one of the main themes of Pantalony’s book. Pantalony shows that Koenig’s atelier was central to disputes surrounding the creation of the “modern soundscape” (p. 170). Debates regarding analytic versus holistic conceptions of sound, “objective” visual versus “subjective” by-ear modes of perception and measurement, and experimental versus theoretical results are all prominent in the text, and all framed by the different, but not disparate, functions of Koenig’s atelier; the building acts as a multi-faceted lens through which Pantalony considers Koenig and his instruments in their artistic, intellectual, commercial and social contexts. (shrink)
Cette livraison de la revue Langages semble avoir un objectif éditorial officiel, affiché dans son titre, consistant à porter un regard réflexif et critique sur les apports et les limites des (grands) corpus à divers domaines de l’analyse linguistique, et un objectif profond, moins immédiatement perceptible mais sans doute premier dans l’esprit des coordinateurs et particulièrement de Marcel Cori, consistant à remettre à sa juste place la linguistique de corpus accusée d’avoir des ambitions h..