11 found
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  1.  5
    Ethics and Collateral Findings in Pragmatic Clinical Trials.Stephanie R. Morain, Kevin Weinfurt, Juli Bollinger, Gail Geller, Debra J. H. Mathews & Jeremy Sugarman - 2020 - American Journal of Bioethics 20 (1):6-18.
    Pragmatic clinical trials offer important benefits, such as generating evidence that is suited to inform real-world health care decisions and increasing research efficiency. However, PCTs also present ethical challenges. One such challenge involves the management of information that emerges in a PCT that is unrelated to the primary research question, yet may have implications for the individual patients, clinicians, or health care systems from whom or within which research data were collected. We term these findings as?pragmatic clinical trial collateral findings,? (...)
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  2.  21
    A Conceptual Model for the Translation of Bioethics Research and Scholarship.Debra J. H. Mathews, D. Micah Hester, Jeffrey Kahn, Amy McGuire, Ross McKinney, Keith Meador, Sean Philpott-Jones, Stuart Youngner & Benjamin S. Wilfond - 2016 - Hastings Center Report 46 (5):34-39.
    While the bioethics literature demonstrates that the field has spent substantial time and thought over the last four decades on the goals, methods, and desired outcomes for service and training in bioethics, there has been less progress defining the nature and goals of bioethics research and scholarship. This gap makes it difficult both to describe the breadth and depth of these areas of bioethics and, importantly, to gauge their success. However, the gap also presents us with an opportunity to define (...)
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  3.  54
    Beyond Consent in Research.Emily Bell, Eric Racine, Paula Chiasson, Maya Dufourcq-Brana, Laura B. Dunn, Joseph J. Fins, Paul J. Ford, Walter Glannon, Nir Lipsman, Mary Ellen Macdonald, Debra J. H. Mathews & Mary Pat Mcandrews - 2014 - Cambridge Quarterly of Healthcare Ethics 23 (3):361-368.
    Vulnerability is an important criterion to assess the ethical justification of the inclusion of participants in research trials. Currently, vulnerability is often understood as an attribute inherent to a participant by nature of a diagnosed condition. Accordingly, a common ethical concern relates to the participant’s decisionmaking capacity and ability to provide free and informed consent. We propose an expanded view of vulnerability that moves beyond a focus on consent and the intrinsic attributes of participants. We offer specific suggestions for how (...)
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  4.  51
    Genome Editing Technologies and Human Germline Genetic Modification: The Hinxton Group Consensus Statement.Sarah Chan, Peter J. Donovan, Thomas Douglas, Chris Gyngell, John Harris, Robin Lovell-Badge, Debra J. H. Mathews & Alan Regenberg - 2015 - American Journal of Bioethics 15 (12):42-47.
    The prospect of using genome technologies to modify the human germline has raised profound moral disagreement but also emphasizes the need for wide-ranging discussion and a well-informed policy response. The Hinxton Group brought together scientists, ethicists, policymakers, and journal editors for an international, interdisciplinary meeting on this subject. This consensus statement formulated by the group calls for support of genome editing research and the development of a scientific roadmap for safety and efficacy; recognizes the ethical challenges involved in clinical reproductive (...)
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  5.  14
    The Therapeutic “Mis”Conception: An Examination of its Normative Assumptions and a Call for its Revision.Debra J. H. Mathews, Joseph J. Fins & Eric Racine - 2018 - Cambridge Quarterly of Healthcare Ethics 27 (1):154-162.
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  6.  67
    Free Will, Self-Governance and Neuroscience: An Overview.Alisa Carse, Hilary Bok & Debra J. H. Mathews - 2018 - Neuroethics 11 (3):237-244.
    Given dramatic increases in recent decades in the pace of scientific discovery and understanding of the functional organization of the brain, it is increasingly clear that engagement with the neuroscientific literature and research is central to making progress on philosophical questions regarding the nature and scope of human freedom and responsibility. While patterns of brain activity cannot provide the whole story, developing a deeper and more precise understanding of how brain activity is related to human choice and conduct is crucial (...)
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  7. Personal Identity and Fractured Selves: Perspectives From Philosophy, Ethics, and Neuroscience.Debra J. H. Mathews, Hilary Bok & Peter V. Rabins (eds.) - 2009 - Johns Hopkins University Press.
    This book brings together some of the best minds in neurology and philosophy to discuss the concept of personal identity and the moral dimensions of treating ...
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  8.  13
    Bottom Up Ethics - Neuroenhancement in Education and Employment.Debra J. H. Mathews, Hilary Bok & Alisa Carse - 2018 - Neuroethics 11 (3):309-322.
    Neuroenhancement involves the use of neurotechnologies to improve cognitive, affective or behavioural functioning, where these are not judged to be clinically impaired. Questions about enhancement have become one of the key topics of neuroethics over the past decade. The current study draws on in-depth public engagement activities in ten European countries giving a bottom-up perspective on the ethics and desirability of enhancement. This informed the design of an online contrastive vignette experiment that was administered to representative samples of 1000 respondents (...)
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  9.  7
    Language Matters.Debra J. H. Mathews - 2014 - Journal of Medical Ethics 40 (11):733-734.
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  10.  8
    Resisting the Tide of Professionalization: Valuing Diversity in Bioethics.Alan C. Regenberg & Debra J. H. Mathews - 2005 - American Journal of Bioethics 5 (5):44 – 45.
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  11.  7
    Artificial Intelligence in Service of Human Needs: Pragmatic First Steps Toward an Ethics for Semi-Autonomous Agents.Travis N. Rieder, Brian Hutler & Debra J. H. Mathews - 2020 - American Journal of Bioethics Neuroscience 11 (2):120-127.