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  1.  4
    The Logic of Medicine.Edmond A. Murphy - 1997 - Johns Hopkins University Press.
    When first published twenty years ago, The Logic of Medicine presented a new way of thinking about clinical medicine as a scholarly discipline as well as a profession. Since then, advances in research and technology have revolutionized both the practice and theory of medicine. In this new, extensively rewritten edition, Dr. Murphy includes changes to show how these different areas of scholarship may affect details of "the logic of medicine" without compromising its fundamental coherence. New to this edition are discussions (...)
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  2.  5
    The Normal, and the Perils of the Sylleptic Argument.Edmond A. Murphy - 1972 - Perspectives in Biology and Medicine 15 (4):566-582.
  3. Angular Homeostasis: III. The Formalism of Discrete Orbits in Ontogeny.Kenneth R. Berger & Edmond A. Murphy - 1989 - Theoretical Medicine and Bioethics 10 (4).
    The formal properties of orbits in a plane are explored by elementary topology. The notions developed from first principles include: convex and polygonal orbits; convexity; orientation, winding number and interior; convex and star-shaped regions. It is shown that an orbit that is convex with respect to each of its interior points bounds a convex region. Also, an orbit that is convex with respect to a fixed point bounds a star-shaped region.Biological considerations that directed interest to these patterns are indicated, and (...)
     
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  4. Angular Homeostasis: IV. Polygonal Orbits.Edmond A. Murphy, Kenneth R. Berger, Joseph E. Trojak & E. Manuel Rosell - 1989 - Theoretical Medicine and Bioethics 10 (4).
    Some properties are discussed of regular polygons that may result from angular homeostatic processes in stable orbit. To characterize these homeostatic polygons we need to discuss the winding number, the sidedness (integer, fractional and irrational), multiplicity, envelopes, and density. A regular (i.e., equilateral, equiangular) polygon may be closed in one revolution about its unique center, in multiple revolutions, or not at all. A homeostatic polygon can be generated only if all vertices are included in a single polygon, which occurs if (...)
     
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  5.  15
    A Scientific Viewpoint on Normalcy.Edmond A. Murphy - 1966 - Perspectives in Biology and Medicine 9 (3):333-348.
  6. Deduction, Inference and Illation.Edmond A. Murphy, E. Manuel Rossell & Magdalena I. Rosell - 1986 - Theoretical Medicine and Bioethics 7 (3).
    From the standpoint of the theory of medicine, a formulation is given of three types of reasoning used by physicians. The first is deduction from probability models (as in prognosis or genetic counseling for Mendelian disorders). It is a branch of mathematics that leads to predictive statements about outcomes of individual events in terms of known formal assumptions and parameters. The second type is inference (as in interpreting clinical trials). In it the arguments from replications of the same process (data) (...)
     
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  7.  48
    Skewness and Asymmetry of Distributions.Edmond A. Murphy - 1982 - Theoretical Medicine and Bioethics 3 (1):87-99.
    The skewness of a distribution, a poorly-defined term, is conventionally deemed to be invariant under linear transformations. A comparison is made of three criteria of it: the sign of odd central moments; the several relationships of the mean, the median and the mode; and asymmetry proper which is the set of ratios of the probability densities of all pairs of points equidistant above and below some arbitrary point, usually the principal mode. Some useful general relationships are discussed. The skeness of (...)
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  8.  7
    Skewness and Asymmetry of Distributions.Edmond A. Murphy - 1982 - Metamedicine 3 (1):87-99.
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  9.  30
    Some Epistemological Aspects of the Model in Medicine.Edmond A. Murphy - 1978 - Journal of Medicine and Philosophy 3 (4):273-292.
    SummaryCertain revolutionary changes in medicine—measurement, chemistry, genetics—have led to recasting both the criteriology and the conceptualization of the terms of discourse. But advances along this path rest no longer on naive observation but intimately and inextricably involve modeling, that is, a system of inference which derives no immediate warrant from the primordial data of the senses. This system is not totally new in quality, since all “fact” involves interpretation of data; nor is it entirely new in having heuristic value in (...)
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  10.  28
    The Analysis and Interpretation of Experiments: Some Philosophical Issues.Edmond A. Murphy - 1982 - Journal of Medicine and Philosophy 7 (4):307-326.
    The epistemology and ontology of experimentation are discussed in depth with special reference to biology and medicine. Two types of experiments are distinguished: exploratory (or "blazing") and consolidating. They Have objectives and canons that are strikingly different. A contrast is drawn between the literalism of the most pragmatic scientists and the formalism of most statisticians. The terms and notions of the one may have imperfect correspondence with those of the other, or perhaps none at all. The dangers are pointed out (...)
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  11. The Diagnostic Process, the Diagnosis and Homeostasis.Edmond A. Murphy - 1988 - Theoretical Medicine and Bioethics 9 (2).
    In this paper I shall try to analyse appropriate logic and actual methods as a preliminary to developing expert systems that will simulate clinical diagnosis. It is doubtful that all diagnoses address the same kind of problem and hence no one logic will suffice. Sometimes the signs and symptoms manifest an underlying disorder that cannot be observed directly (the substantialist model); sometimes there seems to be no underlying disorder and the diagnosis is a rearrangement of the data (the nominalist model). (...)
     
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  12. The Logic of Medicine.Edmond A. Murphy - 1978 - Philosophy of Science 45 (3):488-490.
     
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  13.  48
    The Pursuit of the Minor Premise a Commentary on Normality.Edmond A. Murphy - 1981 - Theoretical Medicine and Bioethics 2 (3):283-299.
    In this paper are explored the ethical implications of the answers to three questions: Whether or not a diseased state is discrete; the criteria by which that question is answered; and how the diseased state is to be identified. Examples are given showing that some states appear to be clearly discrete, and others equally clearly not discrete. The nature of the pertinent evidence will be affected accordingly. It is shown that a slavish and inappropriate concern with categories leads to anomalous (...)
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  14.  2
    The Pursuit of the Minor Premise a Commentary on Normality.Edmond A. Murphy - 1981 - Metamedicine 2 (3):283-299.
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  15. Underpinnings of Medical Ethics.Edmond A. Murphy - 1997 - Johns Hopkins University Press.
    Thus far in the development of the discipline of medical ethics, the overriding concern has been with solutions to specific problems. But discussion is hampered by lack of understanding of the scope and methodology of medical ethics, and its scientific and philosophical basis. In Underpinnings of Medical Ethics Edmond A. Murphy, James J. Butzow, and Edward L. Suarez-Murias offer much-needed clarification of the purview, ontological basis, and methodology of a medical ethics that is to be comprehensive and yet readily accepted (...)
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