Results for 'Emanuel-Mihail Socaciu'

594 found
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  1.  13
    Filosofia științelor umane. In memoriam Mihail Radu Solcan.Mircea Flonta, Emanuel-Mihail Socaciu & Constantin Vica (eds.) - 2015 - Bucharest: Editura Universității din București.
    A collective volume in memoriam Mihail Radu Solcan.
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  2.  9
    How Drug Patents Might Lead to Disincentives for Moral Bioenhancement.Emanuel Mihail Socaciu & Radu Uszkai - 2015 - Ethics in Biology, Engineering and Medicine: An International Journal 6 (1-2):125-137.
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  3.  8
    How Drug Patents Might Provide Disincentives for Moral Bioenhancement.Emanuel Mihail Socaciu & Radu Uszkai - forthcoming - Ethics in Biology, Engineering and Medicine: An International Journal.
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  4.  32
    Mind the Gap! How the Digital Turn Upsets Intellectual Property.Constantin Vică & Emanuel-Mihail Socaciu - 2019 - Science and Engineering Ethics 25 (1):247-264.
    Intellectual property is one of the highly divisive issues in contemporary philosophical and political debates. The main objective of this paper is to explore some sources of tension between the formal rules of intellectual property (particularly copyright and patents) and the emerging informal norms of file sharing and open access in online environments. We look into the file sharing phenomena not only to illustrate the deepening gap between the two sets of norms, but to cast some doubt on the current (...)
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  5. Emanuel-Mihail socaciu.Radu-Bogdan Uszkai - 2012 - Journal for the Study of Religions and Ideologies 11 (33):89-106.
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  6. Etică și integritate academică.Emanuel Socaciu, Constantin Vica, Emilian Mihailov, Toni Gibea, Valentin Muresan & Mihaela Constantinescu - 2018 - Bucharest: Editura Universității din București.
  7. Linda L. Emanuel and Ezekiel J. Emanuel.Ezekiel J. Emanuel - forthcoming - Contemporary Issues in Bioethics.
  8.  13
    Fusionism, Religion and the Tea Party.Uszkai Radu-Bogdan & Socaciu Emanuel-Mihail - 2012 - Journal for the Study of Religions and Ideologies 11 (33):89-106.
    This article aims to explore two different but interrelated problems. The first objective, the more abstract one, is to discuss the plausibility of fusionism as a theoretical project of bridging the philosophical gap between libertarianism and free-market conservatism. Our thesis is that while fusionism could succeed, as a strategic alliance, in promoting specific policies, the differences between libertarianism and conservatism are irreconcilable at the level of fundamental intellectual assumptions. More precisely, starting from Hayek’s objections to conservatism, we argue that the (...)
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  9. Principles for Allocation of Scarce Medical Interventions.Govind Persad, Alan Wertheimer & Ezekiel J. Emanuel - 2009 - The Lancet 373 (9661):423--431.
    Allocation of very scarce medical interventions such as organs and vaccines is a persistent ethical challenge. We evaluate eight simple allocation principles that can be classified into four categories: treating people equally, favouring the worst-off, maximising total benefits, and promoting and rewarding social usefulness. No single principle is sufficient to incorporate all morally relevant considerations and therefore individual principles must be combined into multiprinciple allocation systems. We evaluate three systems: the United Network for Organ Sharing points systems, quality-adjusted life-years, and (...)
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  10.  48
    Fair Allocation of Scarce Medical Resources in the Time of Covid-19.Ezekiel J. Emanuel, Govind Persad, Ross Upshur, Beatriz Thome, Michael Parker, Aaron Glickman, Cathy Zhang, Connor Boyle & James P. Phillips - 2020 - New England Journal of Medicine:10.1056/NEJMsb2005114.
    Four ethical values — maximizing benefits, treating equally, promoting and rewarding instrumental value, and giving priority to the worst off — yield six specific recommendations for allocating medical resources in the Covid-19 pandemic: maximize benefits; prioritize health workers; do not allocate on a first-come, first-served basis; be responsive to evidence; recognize research participation; and apply the same principles to all Covid-19 and non–Covid-19 patients.
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  11.  21
    The Ethics of COVID-19 Immunity-Based Licenses (“Immunity Passports”).Govind Persad & Ezekiel J. Emanuel - 2020 - Journal of the American Medical Association:doi:10.1001/jama.2020.8102.
    Certifications of immunity are sometimes called “immunity passports” but are better conceptualized as immunity-based licenses. Such policies raise important questions about fairness, stigma, and counterproductive incentives but could also further individual freedom and improve public health. Immunity licenses should not be evaluated against a baseline of normalcy, ie, uninfected free movement. Rather, they should be compared to the alternatives of enforcing strict public health restrictions for many months or permitting activities that could spread infection, both of which exacerbate inequalities and (...)
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  12. The Obligation to Participate in Biomedical Research.G. Owen Schaefer, Ezekiel J. Emanuel & Alan Wertheimer - 2009 - Journal of the American Medical Association 302 (1):67-72.
    The current prevailing view is that participation in biomedical research is above and beyond the call of duty. While some commentators have offered reasons against this, we propose a novel public goods argument for an obligation to participate in biomedical research. Biomedical knowledge is a public good, available to any individual even if that individual does not contribute to it. Participation in research is a critical way to support an important public good. Consequently, all have a duty to participate. The (...)
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  13.  81
    The Oxford Textbook of Clinical Research Ethics.Ezekiel J. Emanuel (ed.) - 2008 - Oxford University Press.
    Comprehensive in scope and research, this book will be a crucial resource for researchers in the medical sciences, as well as teachers and students alike.
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  14.  49
    Undue Inducement: Nonsense on Stilts?Ezekiel J. Emanuel - 2005 - American Journal of Bioethics 5 (5):9-13.
    1. The opinions expressed are the author's own. They do not reflect any position or policy of the National Institutes of Health, Public Health Service, Department of Health and Human Services, or any of the authors affiliated organizations.
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  15.  17
    Moral Standards for Research in Developing Countries From "Reasonable Availability" to "Fair Benefits".Maged El Setouhy, Tsiri Agbenyega, Francis Anto, Christine Alexandra Clerk, Kwadwo A. Koram, Michael English, Rashid Juma, Catherine Molyneux, Norbert Peshu, Newton Kumwenda, Joseph Mfutso-Bengu, Malcolm Molyneux, Terrie Taylor, Doumbia Aissata Diarra, Saibou Maiga, Mamadou Sylla, Dione Youssouf, Catherine Olufunke Falade, Segun Gbadegesin, Reidar Lie, Ferdinand Mugusi, David Ngassapa, Julius Ecuru, Ambrose Talisuna, Ezekiel Emanuel, Christine Grady, Elizabeth Higgs, Christopher Plowe, Jeremy Sugarman & David Wendler - 2004 - Hastings Center Report 34 (3):17.
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  16.  61
    Exploitation and Developing Countries: The Ethics of Clinical Research.Jennifer S. Hawkins & Ezekiel J. Emanuel - 2008 - Princeton, NJ, USA: Princeton Univ Pr.
    This book was inspired originally by the debates at the turn of the century about placebo controlled trials of antiretrovirals in HIV positive pregnant women in developing countries. Moving forward from this one limited example, the book includes several additional controversial cases of clinical research conducted in developing countries, and asks probing philosophical questions about the ethics of such trials. All clinical research by its very nature uses people to acquire generalizable knowledge to help future people. But what sorts of (...)
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  17. The Quality of Informed Consent: Mapping the Landscape. A Review of Empirical Data From Developing and Developed Countries.A. Mandava, C. Pace, B. Campbell, E. Emanuel & C. Grady - 2012 - Journal of Medical Ethics 38 (6):356-365.
    Objective Some researchers claim that the quality of informed consent of clinical research participants in developing countries is worse than in developed countries. To evaluate this assumption, we reviewed the available data on the quality of consent in both settings. Methods We conducted a comprehensive PubMed search, examined bibliographies and literature reviews, and consulted with international experts on informed consent in order to identify studies published from 1966 to 2010 that used quantitative methods, surveyed participants or parents of paediatric participants (...)
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  18. The Case for Resource Sensitivity: Why It Is Ethical to Provide Cheaper, Less Effective Treatments in Global Health.Govind C. Persad & Ezekiel J. Emanuel - 2017 - Hastings Center Report 47 (5):17-24.
    We consider an ethical dilemma in global health: is it ethically acceptable to provide some patients cheaper treatments that are less effective or more toxic than the treatments other patients receive? We argue that it is ethical to consider local resource constraints when deciding what interventions to provide. The provision of cheaper, less effective health care is frequently the most effective way of promoting health and realizing the ethical values of utility, equality, and priority to the worst off.
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  19. Philosophical Justifications of Informed Consent in Research.D. Brock, E. J. Emanuel, C. Grady, R. Lie, F. Miller & D. Wendler - 2008 - In Ezekiel J. Emanuel (ed.), The Oxford Textbook of Clinical Research Ethics. Oxford University Press.
     
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  20.  45
    Ending Concerns About Undue Inducement.Ezekiel J. Emanuel - 2004 - Journal of Law, Medicine and Ethics 32 (1):100-105.
  21.  29
    An Ethical Framework for Biomedical Research.Ezekiel J. Emanuel, David Wendler & C. Grady - 2008 - In The Oxford Textbook of Clinical Research Ethics. Oxford University Press. pp. 123--135.
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  22. Empirical Issues in Informed Consent for Research.James Flory, David Wendler & Ezekiel Emanuel - 2008 - In Ezekiel J. Emanuel (ed.), The Oxford Textbook of Clinical Research Ethics. Oxford University Press. pp. 645--60.
     
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  23. The Current State of Medical School Education in Bioethics, Health Law, and Health Economics.Govind C. Persad, Linden Elder, Laura Sedig, Leonardo Flores & Ezekiel J. Emanuel - 2008 - Journal of Law, Medicine and Ethics 36 (1):89-94.
    Current challenges in medical practice, research, and administration demand physicians who are familiar with bioethics, health law, and health economics. Curriculum directors at American Association of Medical Colleges-affiliated medical schools were sent confidential surveys requesting the number of required hours of the above subjects and the years in which they were taught, as well as instructor names. The number of relevant publications since 1990 for each named instructor was assessed by a PubMed search.In sum, teaching in all three subjects combined (...)
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  24.  14
    Ending Concerns About Undue Inducement.Ezekiel J. Emanuel - 2004 - Journal of Law, Medicine and Ethics 32 (1):100-105.
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  25.  27
    Protecting Communities in Biomedical Research.Charles Weijer & E. J. Emanuel - unknown
    Although for the last 50 years, ethicists dealing with human experimentation have focused primarily on the need to protect individual research subjects and vulnerable groups, biomedical research, especially in genetics, now requires the establishment of standards for the protection of communities. We have developed such a strategy, based on five steps. (i) Identification of community characteristics relevant to the biomedical research setting, (ii) delineation of a typology of different types of communities using these characteristics, (iii) determination of the range of (...)
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  26. Ethical and Regulatory Aspects of Clinical Research: Readings and Commentary.Ezekiel J. Emanuel (ed.) - 2003 - Johns Hopkins University Press.
    All investigators funded by the National Institutes of Health are now required to receive training about the ethics of clinical research. Based on a course taught by the editors at NIH, Ethical and Regulatory Aspects of Clinical Research is the first book designed to help investigators meet this new requirement. The book begins with the history of human subjects research and guidelines instituted since World War II. It then covers various stages and components of the clinical trial process: designing the (...)
     
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  27.  2
    New Technologies Smart, or Harm Work-Family Boundaries Management? Gender Differences in Conflict and Enrichment Using the JD-R Theory.Chiara Ghislieri, Federica Emanuel, Monica Molino, Claudio G. Cortese & Lara Colombo - 2017 - Frontiers in Psychology 8.
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  28. Clinical Research: Should Patients Pay to Play?Ezekiel J. Emanuel, Steven Joffe, Christine Grady, David Wendler & Govind Persad - 2015 - Science Translational Medicine 7 (298):298ps16.
    We argue that charging people to participate in research is likely to undermine the fundamental ethical bases of clinical research, especially the principles of social value, scientific validity, and fair subject selection.
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  29.  24
    Money and Distorted Ethical Judgments About Research: Ethical Assessment of the TeGenero TGN1412 Trial. [REVIEW]Ezekiel J. Emanuel & Franklin G. Miller - 2007 - American Journal of Bioethics 7 (2):76-81.
    The recent TeGenero phase I trial of a novel monoclonal antibody in healthy volunteers produced a drastic inflammatory reaction in participants receiving the experimental agent. Commentators on the ethics of the research have focused considerable attention on the role of financial considerations: the for-profit status of the biotechnology company and Contract Research Organization responsible respectively for sponsoring and conducting the trial and the amount of monetary compensation to participants. We argue that these financial considerations are largely irrelevant and distort ethical (...)
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  30. The Moral Duty to Buy Health Insurance.Tina Rulli, Ezekiel Emanuel & David Wendler - 2012 - Journal of the American Medical Association 308 (2):137-138.
    The 2010 Patient Protection and Affordable Care Act was designed to increase health insurance coverage in the United States. Its most controversial feature is the requirement that US residents purchase health insurance. Opponents of the mandate argue that requiring people to contribute to the collective good is inconsistent with respect for individual liberty. Rather than appeal to the collective good, this Viewpoint argues for a duty to buy health insurance based on the moral duty individuals have to reduce certain burdens (...)
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  31.  19
    Comprehension and Informed Consent: Assessing the Effect of a Short Consent Form.Leanne Stunkel, Meredith Benson, Louise McLellan, Ninet Sinaii, Gabriella Bedarida, Ezekiel Emanuel & Christine Grady - 2010 - IRB: Ethics & Human Research 32 (4):1.
    The objective of this study—a substudy to a phase I bioequivalence study—was to compare the effect of standard and concise consent forms on research volunteers’ comprehension of and satisfaction with consent forms, as well as to assess the effect of select volunteer characteristics, such as financial motivations to participate in research, on their comprehension. A 36-item questionnaire measured volunteers’ comprehension, satisfaction, and motivations for participation. Volunteers were randomized to the standard Pfizer consent form or a concise, easier-to-read form. We approached (...)
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  32.  22
    Research on Stored Biological Samples: The Views of Ugandans.David Wendler, Christine Pace, Ambrose O. Talisuna, Faustine Maiso, Christine Grady & Ezekiel Emanuel - 2005 - IRB: Ethics & Human Research 27 (2).
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  33. The Ethics of Expanding Access to Cheaper, Less Effective Treatments.Govind C. Persad & Ezekiel J. Emanuel - 2016 - The Lancet:S0140-6736(15)01025-9.
    This article examines a fundamental question of justice in global health. Is it ethically preferable to provide a larger number of people with cheaper treatments that are less effective (or more toxic), or to restrict treatments to a smaller group to provide a more expensive but more effective or less toxic alternative? We argue that choosing to provide less effective or more toxic interventions to a larger number of people is favored by the principles of utility, equality, and priority for (...)
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  34. What is the Great Benefit of Legalizing Euthanasia or Physican‐Assisted Suicide?Ezekiel J. Emanuel - 1999 - Ethics 109 (3):629-642.
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  35. Comparing the Understanding of Subjects Receiving a Candidate Malaria Vaccine in the United States and Mali.R. D. Ellis, I. Sagara, A. Durbin, A. Dicko, D. Shaffer, L. Miller, M. H. Assadou, M. Kone, B. Kamate, O. Guindo, M. P. Fay, D. A. Diallo, O. K. Doumbo, E. J. Emanuel & J. Millum - 2010 - American Journal of Tropical Medicine and Hygiene 83 (4):868-72.
    Initial responses to questionnaires used to assess participants' understanding of informed consent for malaria vaccine trials conducted in the United States and Mali were tallied. Total scores were analyzed by age, sex, literacy (if known), and location. Ninety-two percent (92%) of answers by United States participants and 85% of answers by Malian participants were correct. Questions more likely to be answered incorrectly in Mali related to risk, and to the type of vaccine. For adult participants, independent predictors of higher scores (...)
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  36.  39
    The Ends of Human Life: Medical Ethics in a Liberal Polity.Ezekiel J. Emanuel - 1991 - Harvard University Press.
    INTRODUCTION The Questions of Medical Ethics Call him Andrew. His face is gaunt and unshaven but peaceful. His eyelids are gently closed. ...
  37.  43
    Four Paradigms of Clinical Research and Research Oversight.Ezekiel J. Emanuel & Christine Grady - 2007 - Cambridge Quarterly of Healthcare Ethics 16 (1):82-96.
    The understanding of appropriate ethical protections for participants of biomedical research has not been static. It has evolved over time, with the evolution of biomedical research as well as social values. Since World War II, there have been four major paradigms of research and research oversight operative in the United States. These paradigms incorporate different values and provide different approaches to research oversight and the protection of research participants.
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  38.  33
    Refocusing the Responsiveness Requirement.Seema Shah, Rebecca Wolitz & Ezekiel Emanuel - 2013 - Bioethics 27 (3):151-159.
    Many guidelines for international research require that studies be responsive to host community health needs or health priorities. Although responsiveness possesses great intuitive and rhetorical appeal, existing conceptions are confusing and difficult to apply. Not only are there few examples of what research the responsiveness requirement permits and what it rejects, but its application can lead to contradictory results. Because of the practical difficulties in applying responsiveness and the danger that misapplying responsiveness could harm the interests of developing countries, we (...)
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  39.  9
    Clarifying Confusions About Coercion.Jennifer S. Hawkins & Ezekiel J. Emanuel - 2005 - Hastings Center Report 35 (5):16.
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  40.  5
    Secondary Traumatic Stress: Relationship With Symptoms, Exhaustion, and Emotions Among Cemetery Workers.Lara Colombo, Federica Emanuel & Margherita Zito - 2019 - Frontiers in Psychology 10.
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  41.  84
    Clarifying Confusions About Coercion.Jennifer Susan Hawkins & Ezekiel J. Emanuel - 2005 - Hastings Center Report 35 (5):16-19.
    Commentators often claim that medical research subjects are coerced into participating in clinical studies. In recent years, such claims have appeared especially frequently in ethical discussions of research in developing countries. Medical research ethics is more important than ever as we move into the 21st century because worldwide the pharmaceutical industry has grown so much and shows no sign of slowing its growth. This means that more people are involved in medical research today than ever before, and in the future (...)
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  42.  30
    Protecting Communities in Research: Current Guidelines and Limits of Extrapolation.Charles Weijer, Gary Goldsand & Ezekiel J. Emanuel - unknown
    As genetic research increasingly focuses on communities, there have been calls for extending research protections to them. We critically examine guidelines developed to protect aboriginal communities and consider their applicability to other communities. These guidelines are based on a model of researcher-community partnership and span the phases of a research project, from protocol development to publication. The complete list of 23 protections may apply to those few non-aboriginal communities, such as the Amish, that are highly cohesive. Although some protections may (...)
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  43.  8
    A Crossover Study From a Gender Perspective: The Relationship Between Job Insecurity, Job Satisfaction, and Partners’ Family Life Satisfaction.Federica Emanuel, Monica Molino, Alessandro Lo Presti, Paola Spagnoli & Chiara Ghislieri - 2018 - Frontiers in Psychology 9.
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  44.  4
    Key Ethical Concepts and Their Application to COVID-19 Research.Angus Dawson, Ezekiel J. Emanuel, Michael Parker, Maxwell J. Smith & Teck Chuan Voo - forthcoming - Public Health Ethics:phaa017.
    During the WHO-GloPID COVID-19 Global Research and Innovation Forum meeting held in Geneva on the 11th and 12th of February 2020 a number of different ethical concepts were used. This paper briefly states what a number of these concepts mean and how they might be applied to discussions about research during the COVID-19 pandemic and related outbreaks. This paper does not seek to be exhaustive and other ethical concepts are, of course, relevant and important.
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  45. Standing by Our Principles: Meaningful Guidance, Moral Foundations, and Multi-Principle Methodology in Medical Scarcity.Govind C. Persad, Alan Wertheimer & Ezekiel J. Emanuel - 2010 - American Journal of Bioethics 10 (4):46 – 48.
    In this short response to Kerstein and Bognar, we clarify three aspects of the complete lives system, which we propose as a system of allocating scarce medical interventions. We argue that the complete lives system provides meaningful guidance even though it does not provide an algorithm. We also defend the investment modification to the complete lives system, which prioritizes adolescents and older children over younger children; argue that sickest-first allocation remains flawed when scarcity is absolute and ongoing; and argue that (...)
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  46.  89
    The Problem with Single-Payer Plans.Ezekiel J. Emanuel - 2008 - Hastings Center Report 38 (1):38-41.
  47.  28
    Justice and Managed Care: Four Principles for the Just Allocation of Health Care Resources.Ezekiel J. Emanuel - 2000 - Hastings Center Report 30 (3):8-16.
    The debate about justice and health care has occurred largely at a remove from the institutions it concerns; it has been about our most general moral principles, and about what things we value. This debate has foundered. But if the debate is turned in another direction, toward some moral principles that are widely accepted within those institutions, and toward principles that have to do with control over allocation decisions rather than with actually how to make those decisions, agreement may be (...)
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  48.  89
    Improving Access to Health Care: A Consensus Ethical Framework to Guide Proposals for Reform.Mark A. Levine, Matthew K. Wynia, Paul M. Schyve, J. Russell Teagarden, David A. Fleming, Sharon King Donohue, Ron J. Anderson, James Sabin & Ezekiel J. Emanuel - 2007 - Hastings Center Report 37 (5):14-19.
  49. The Concept of Conflicts of Interest.Ezekiel J. Emanuel & Dennis F. Thompson - 2008 - In The Oxford Textbook of Clinical Research Ethics. Oxford University Press. pp. 758--766.
     
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  50.  15
    Ethics and the Structures of Healthcare.Linda L. Emanuel - 2000 - Cambridge Quarterly of Healthcare Ethics 9 (2):151-168.
    Suppose a meeting had been called among chief medical officers, chief administrative officers, and other leaders from a range of health-related institutions in this country. The question posed for this meeting was simple but unusual: Arethestructuresofourorganizations,systems,andinstitutionsethical? Though it was a question reminiscent for a few of the focus some time before on whether the conduct of individuals in their organization was ethical, this question seemed more demanding. Is it reasonable to consider structures or arrangements as ethical or not; or in (...)
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