There are challenges to the dominant research paradigm in breast cancer science. In the United States, science and social activism create paradigmatic shifts. Using interviews, ethnographic observations, and an extensive review of the literature, we create a three-dimensional model to situate changes in scientific controversy concerning environmental causes of breast cancer. We identify three paradigm challenges posed by activists and some scientists: to move debates about causation upstream to address causes; to shift emphasis from individual to modifiable societal-level (...) factors beyond an individual’s control; and to allow direct lay involvement in research, which may raise new questions and change how questions are approached, the methods used, and the standards of proof. We use our model to examine controversies about doing scientific research, interpreting scientific results, and acting on science. Ultimately, we aim to understand what impedes construction of new methodologies and knowledge about environmental factors in human disease. (shrink)

Act utilitarians often use causation in after-the-fact assessments of accountability in group environmental harms. Such attempts are seriously flawed. Causation need not, and many times should not, be important in assessments of accountability for act utilitarians. A model that maximizes utility in such assessments called the “best fit model” provides a good alternative. Because use of this model leads to more utility than models of after-the-fact accountability which rely on causal links, act utilitarians should adhere to the (...) “best fit model” regardless of actual causal links. Although the “best fit model” is a better method to assign accountability using an act utilitarian approach than methods involving causation, it does have a serious flaw in regard to application and future utility. Given this flaw, the model (indeed, any after-the-fact model of accountability) is not enough to ensure future utility maximization. To maximize utility to the fullest, the model should be used along with incentives to prevent environmental harm before it occurs. Perhaps if such incentives are strong enough, the model may not need to be imposed at all. However, in cases where harm does occur, the “best fit model” yields the most utility. Thus, if the “best fit model” is not an acceptable method by which to assess responsibility, neither is act utilitarianism. (shrink)

I argue that a phenotypic trait can be an adaptation to a particular environmental condition, as against others, only if the environmental condition and the phenotype interactively cause fitness. Models of interactive environmental causes of fitness generally require that environments be individuated by explicit representation rather than by measures of environmental quality, although the latter understanding of ‘environment’ is more prominent in the philosophy of biology. Hence, talk of adaptations to some but not other environmental (...) conditions relies on conceptions of ‘environment’ importantly different from that commonly presupposed in philosophy of biology. (shrink)

The sociogenomics revolution is upon us, we are told. Whether revolutionary or not, sociogenomics is poised to flourish given the ease of incorporating polygenic scores (or PGSs) as “genetic propensities” for complex traits into social science research. Pointing to evidence of ubiquitous heritability and the accessibility of genetic data, scholars have argued that social scientists not only have an opportunity but a duty to add PGSs to social science research. Social science research that ignores genetics is, some proponents argue, at (...) best partial and likely scientifically flawed, misleading, and wasteful. Here, I challenge arguments about the value of genetics for social science and with it the claimed necessity of incorporating PGSs into social science models as measures of genetic influences. In so doing, I discuss the impracticability of distinguishing genetic influences from environmental influences because of non-causal gene–environment correlations, especially population stratification, familial confounding, and downward causation. I explain how environmental effects masquerade as genetic influences in PGSs, which undermines their raison d’être as measures of genetic propensity, especially for complex socially contingent behaviors that are the subject of sociogenomics. Additionally, I draw attention to the partial, unknown biology, while highlighting the persistence of an implicit, unavoidable reductionist genes versus environments approach. Leaving sociopolitical and ethical concerns aside, I argue that the potential scientific rewards of adding PGSs to social science are few and greatly overstated and the scientific costs, which include obscuring structural disadvantages and cultural influences, outweigh these meager benefits for most social science applications. (shrink)

Instrumental values are often considered to be inferior to intrinsic values. One reason for this is that instrumental values are extrinsic and rely on two factors: (a) a means–end relationship that is (b) conducive to something of final or intrinsic value. In this paper, I will investigate the conditions under which bearers of instrumental value are given different value or owed different levels of respect. Such conditions include the number of means that are conducive to something of final or intrinsic (...) value as well as the form of causality that is implied. It will be suggested that different numbers and causal relations will imply different degrees of reverence or respect to the bearers of instrumental value. I will also critically investigate recent proposals such as relational values that allegedly go beyond the distinction between instrumental and intrinsic value. Drawing from this critical analysis, a nuanced picture of instrumental value will be provided. (shrink)

This paper develops a philosophical account of environmental racism and explains why having such an account is worthwhile. After reviewing some data points and common uses of the term linking environmental racism to the distribution of environmental burdens by race, I argue that environmental racism should be understood as referring to an unequal distribution caused by a history of racism. Environmental racism is thus analyzed in terms of two conditions: first, that environmental burdens and (...) benefits be distributed according to race, and second, that this distribution be partly caused by a history of racism, where this causal claim is understood counterfactually. The account entails that environmental racism is a derivative form of racism – it depends on other kinds of racism to exist – while being compatible with a variety of views about the more basic forms of racism. Given the proposed framework, I consider the kind of evidence needed to establish whether a given case is one of environmental racism and make the case for environmental racism being a concept worth focusing on as it can highlight a type of injustice that may otherwise go unnoticed. (shrink)

The actions performed by individuals, as consumers and citizens, have aggregate negative consequences for the environment. The question asked in this paper is to what extent it is reasonable to hold individuals and institutions responsible for environmental problems. A distinction is made between backward-looking and forward-looking responsibility. Previously, individuals were not seen as being responsible for environmental problems, but an idea that is now sometimes implicitly or explicitly embraced in the public debate on environmental problems is that (...) individuals are appropriate targets for blame when they perform actions that are harmful to the environment. This idea is criticized in this paper. It is argued that instead of blaming individuals for performing actions that are not environmentally friendly we should ascribe forward-looking responsibility to individuals, a notion that focuses more on capacity and resources than causation and blameworthiness. Furthermore, it is important to emphasize that a great share of forward-looking responsibility should also be ascribed to institutional agents, primarily governments and corporations. The urge to ascribe forward-looking responsibility to institutional agents is motivated by the efficiency aim of responsibility distributions. Simply put, if responsibility is ascribed to governments and corporations there is a better chance of creating a society in which the opportunities to act in an environmentally friendly way increase. (shrink)

Moral judgments about a situation are profoundly shaped by the perception of individuals in that situation as either moral agents or moral patients (Gray & Wegner, 2009; Gray, Young, & Waytz, 2012), Specifically, the more we see someone as a moral agent, the less we see them as a moral patient, and vice versa. As a result, casting the perpetrator of a transgression as a victim tends to have the effect of making them seem less blameworthy (Gray & Wegner, 2011). (...) Based on this theoretical framework, we predicted that criminal offenders with a mental disorder that predisposes them to antisocial behavior would be judged more negatively when the disorder is described as having a genetic origin than when it is described as environmentally caused, as in the case of childhood abuse or accident. Further, we predicted that some environmental explanations would mitigate attributions of blame more than others, namely, that offenders whose disorder was caused by childhood abuse (intentional harm) would be seen as less blameworthy than offenders whose disorder is caused by an unfortunate accident (unintentional harm). Results from two vignette-based studies designed to test these predictions, conducted with participants recruited from Amazon Mechanical Turk (N = 244 and N = 387, respectively), confirmed the first prediction but not the second. Implications of this research for three areas — the psychology of moral judgment, philosophical debates about moral responsibility and determinism, and the practice of the law — are discussed in the sequel. (shrink)

Developmental biology is expanding into several new areas. One new area of study concerns the production of adult-onset phenotypes by exposure of the fetus or neonate to environmental agents. These agents include maternal nutrients, developmental modulators (endocrine disruptors), and maternal care. In all three cases, a major mechanism for the generation of the altered phenotype is chromatin modification. Nutrient conditions, developmental modulators, and even maternal care appear to alter DNA methylation and other associated changes in chromatin that regulate gene (...) expression. This brings a new, under-appreciated, dimension of gene regulation into developmental biology, and it also demonstrates the poverty of the nature versus nurture framework for discussing phenotype production. Moreover, while such epigenetic mechanisms undermine genetic determinism, they add a layer of probabilistic biological causality for the maintenance of social inequalities. (shrink)

The problem of natural teleology in biology has traditionally focused on reconciling Aristotle’s efficient and final causation. In this paper, however, I emphasize the importance of formal causation in natural teleological explanations and suggest that undermining its legitimacy is a backdoor route to undermining natural teleology itself. Formal causation, I argue, represents the “phenotype” of an object, to use a familiar word from genetics. This means that formal causes specify not only intrinsic “genotypic” qualities of an object (...) but also a range of environments in which the object is “properly” to inhabit. Such environmental specificity is possible through conscious activity, but is not found anywhere in non-conscious nature. Das Problem der natürlichen Teleologie ist traditionellerweise darin gesehen worden, Aristoteles’ Wirkursache und seine Finalursache miteinander zu vereinbaren. Dagegen betone ich in diesem Aufsatz die Bedeutung der formalen Verursachung in natürlichen teleologischen Erklärungen. Wenn man ihre Legitimität untergräbt, so lege ich nahe, untergräbt man gleichsam durch die Hintertür natürliche Teleologie als solche. Ich argumentiere, dass formale Verursachung den „Phänotyp“ eines Objekts darstellt, um ein geläufiges Wort aus der Genetik zu verwenden. Dies bedeutet, dass formale Ursachen nicht nur intrinsische „genotypische“ Eigenschaften eines Objekts spezifizieren, sondern auch eine Bandbreite von Umgebungen, in denen das Objekt „im eigentlichen Sinn“ angesiedelt sein sollte. Diese Spezifizierung der Umgebung ist durch bewusste Aktivität möglich, findet sich aber nirgendwo in der nicht-bewussten Natur. (shrink)

Many models of evolution are implicitly causal processes. Features such as causal feedback between evolutionary variables and evolutionary processes acting at multiple levels, though, mean that conventional causal models miss important phenomena. We develop here a general theoretical framework for analyzing evolutionary processes drawing on recent approaches to causal modeling developed in the machine-learning literature, which have extended Pearls do-calculus to incorporate cyclic causal interactions and multilevel causation. We also develop information-theoretic notions necessary to analyze causal information dynamics in (...) our framework, introducing a causal generalization of the Partial Information Decomposition framework. We show how our causal framework helps to clarify conceptual issues in the contexts of complex trait analysis and cancer genetics, including assigning variation in an observed trait to genetic, epigenetic and environmental sources in the presence of epigenetic and environmental feedback processes, and variation in fitness to mutation processes in cancer using a multilevel causal model respectively, as well as relating causally-induced to observed variation in these variables via information theoretic bounds. In the process, we introduce a general class of multilevel causal evolutionary processes which connect evolutionary processes at multiple levels via coarse-graining relationships. Further, we show how a range of fitness models can be formulated in our framework, as well as a causal analog of Prices equation, clarifying the relationships between realized/probabilistic fitness and direct/indirect selection. Finally, we consider the potential relevance of our framework to foundational issues in biology and evolution, including supervenience, multilevel selection and individuality. Particularly, we argue that our class of multilevel causal evolutionary processes, in conjunction with a minimum description length principle, provides a conceptual framework in which identification of multiple levels of selection may be reduced to a model selection problem. (shrink)

Genetic differences can lead to phenotypic differences either directly or indirectly (via causing differences in external environments, which then affect phenotype). This possibility of genetic effects being mediated by environmental influences is often used by scientists and philosophers to argue that heritability is not a very helpful causal or explanatory notion. In this paper it is shown that these criticisms are based on serious misconceptions about methods of behavior genetics.

This study draws on neo-institutional theory to examine how and why corporate environmental management practices might affect environmental performance. It contributes to the literature by using a large, global data set to investigate the impact of 10 corporate environmental management practices on greenhouse gas emissions or emissions intensity. It focuses on greenhouse gas emissions which pose an existential threat to the people and planet, and the environmental management practices of corporations whose effectiveness has provoked cynicism and (...) claims of “greenwash”. Our results are based on a dynamic, robust and large-scale econometric analysis, which includes tests of association and Granger causation in comparison with earlier research. A key finding, which is of interest not only to the academic literature but also to policymakers and managers, is that environmental performance impacts environmental management practices but not vice versa, supporting the hypothesis that corporations adopt these practices as a symbolic legitimizing device rather than a genuine attempt derived from moral obligation to reduce their greenhouse gases or carbon intensity. (shrink)

Heyman explains useful ways to bring addictive drug use under environmental control. We doubt that relapse is explained by drug features such as immediate reinforcement, clouding of judgment, and so forth. Relapse may require explanation in terms of enduring sensitization of incentive neural substrates, but even if its causal assumptions are wrong, Heyman's model makes useful predictions for behavioral control.

If, as I argue, the law of karma is a special application of the causal law to moral causation, then one has to account for the differences between the two laws. One possibility is to distinguish between "phalas" (immediate effects actions produce in the world) and "samskaras" (invisible dispositions or tendencies to act or think), and to suggest that karma produces the latter but not the former. This subjectivist account, however, raises questions concerning the relation between a person's "samskaras" (...) and the environmental conditions that cause him pleasure and pain. (shrink)

In the succession of states of consciousness that constitute James’s stream of consciousness, there occur, among others, states of consciousness that are themselves, or that include, perceptual mental acts. It is assumed some of the latter states of consciousness are purely perceptual, lacking both imaginal and signitive contents. According to Husserl, purely perceptual acts present to consciousness, uniquely, their environmental objects in themselves, in person. They do not present, as imaginal mental acts do, an image or other representation of (...) their object. Husserl’s theory resembles Gibson’s with respect to perception’s being direct. Both theorists hold perceptual awareness of the environment is not a "founded" act; its proximate causation does not involve any other mental act. Both theorists contend that perceptual acts keep the perceiver directly in touch with the surrounding environment. The present article considers Husserl’s account of this directness. Although this account has problems, and is largely phenomenological description, it may help psychologists to find their way to an adequate account of the objects of perceptual consciousness — perhaps if it is integrated with Gibson’s perception theory, as I will attempt in a sequel to which this article is introductory. Husserl seeks to provide the phenomenological side of the story, Gibson the stimulus-informational side. (shrink)

Explaining the causal mechanisms that contribute to autism spectrum disorder occurrence remains a conundrum in developmental medicine, neuroscience, and child psychiatry. Recent research has resulted in agreement on behavioral definitions and their underlying cognitive processes, early diagnosis and standardized assessments, evidence-based interventions, systems-level approaches to neurobiology, and identification of genetic variants and their interaction with epigenetic and environmental factors. However, an explanatory model of autism causation remains elusive.Perhaps..

Due to the highly visible nature of the disease, smallpox received a lot of attention from the colonial and independent Indian governments. An assessment of the changing official views about the impact of geographical and environmental factors on modes of variola causation and control presents insights into themes that are generally ignored in the existing historiography. Rather than being synchronised efforts, imposed top-down, provincial level officials in charge of running vaccination programmes were able to retain a great degree (...) of autonomy and shape the nature of local immunisation drive. As a result, vaccination work in the country was often disjointed, marked by official disagreements about the usefulness of certain strategies and technological inputs, with these trends being most noticeable in rural areas. Thus, this study seeks to highlight the importance of recognising — and studying — the fractured nature of medical and public health administration in the South Asian sub-continent. (shrink)

The concept of green jobs emerged in 2007 as a means for conserving energy, minimizing natural gas emissions, reducing pollution and waste and protecting and improving ecosystems. The practice of decent employment through such jobs has caught on significantly and shown much positive effects. Decent work refers to employment opportunities that provide for fair income, security, improving personal and social development and promoting equality. Combining green job and decent work as a new approach can alter the traditional perspective of labour (...) laws. According to the Islamic view, the Qur’an has taken into account all such concepts directly or indirectly. This article focuses on reviewing green jobs from the Islamic perspective, and concepts and principles such as squander, cleanliness, waste, no-harm and causation are directly mentioned as a necessary condition for green jobs. This paper examines the concept of green job based on content analysis approach within Islamic jurisprudence. (shrink)

Quarterly publication discussing various topics in environmental ethics, including features, discussion papers, book reviews, editorial commentaries, and other text related to environmental philosophies. Some issues also include announcements and other news related to the environmental studies community.

Quarterly publication discussing various topics in environmental ethics, including features, discussion papers, book reviews, editorial commentaries, and other text related to environmental philosophies. Some issues also include announcements and other news related to the environmental studies community.

Quarterly publication discussing various topics in environmental ethics, including features, discussion papers, book reviews, editorial commentaries, and other text related to environmental philosophies. Some issues also include announcements and other news related to the environmental studies community.

Quarterly publication discussing various topics in environmental ethics, including features, discussion papers, book reviews, editorial commentaries, and other text related to environmental philosophies. Some issues also include announcements and other news related to the environmental studies community.

Quarterly publication discussing various topics in environmental ethics, including features, discussion papers, book reviews, editorial commentaries, and other text related to environmental philosophies. Some issues also include announcements and other news related to the environmental studies community.

Quarterly publication discussing various topics in environmental ethics, including features, discussion papers, book reviews, editorial commentaries, and other text related to environmental philosophies. Some issues also include announcements and other news related to the environmental studies community.

Quarterly publication discussing various topics in environmental ethics, including features, discussion papers, book reviews, editorial commentaries, and other text related to environmental philosophies. Some issues also include announcements and other news related to the environmental studies community.

Quarterly publication discussing various topics in environmental ethics, including features, discussion papers, book reviews, editorial commentaries, and other text related to environmental philosophies. Some issues also include announcements and other news related to the environmental studies community.

Quarterly publication discussing various topics in environmental ethics, including features, discussion papers, book reviews, editorial commentaries, and other text related to environmental philosophies. Some issues also include announcements and other news related to the environmental studies community.

Quarterly publication discussing various topics in environmental ethics, including features, discussion papers, book reviews, editorial commentaries, and other text related to environmental philosophies. Some issues also include announcements and other news related to the environmental studies community.

Quarterly publication discussing various topics in environmental ethics, including features, discussion papers, book reviews, editorial commentaries, and other text related to environmental philosophies. Some issues also include announcements and other news related to the environmental studies community.

Ethical reasoning of all types is anthropocentric, in that it is addressed to agents, but anthropocentric starting points vary in the preference they accord the human species. Realist claims about environmental values, utilitarian reasoning and rights-based reasoning all have difficulties in according ethical concern to certain all aspects of natural world. Obligation-based reasoning can provide quite strong if incomplete reasons to protect the natural world, including individual non-human animals. Although it cannot establish all the conclusions to which anti-speciesists aspire, (...) it may establish many of them with some clarity. (shrink)

Contemporary architecture is increasingly grounded in science and mathematics. Architectural discourse has shifted radically from the sometimes disorienting Derridean deconstruction, to engaging scientific terms such as fractals, chaos, complexity, nonlinearity, and evolving systems. That's where the architectural action is -- at least for cutting-edge architects and thinkers -- and every practicing architect and student needs to become conversant with these terms and know what they mean. Unfortunately, the vast majority of architecture faculty are unprepared to explain them to students, not (...) having had a scientific education themselves. Here is an architecture book by an architect/scientist, just in time to help architects in the new millennium. Alexander discusses many of the scientific terms arising in cutting-edge architecture, and explains them to those who don't have scientific training or advanced mathematical knowledge. We find discussions of the evolution of forms; the importance of process in design; iteration; genetic algorithms; sequences of transformations; different levels of scale (i.e. fractals); etc. They are explained here by an architect who is also a scientist, because he wants to change the way architects think and build. Alexander is not merely popularizing other scientists' results and making them accessible to architects: he is in fact presenting new and original scientific work that ties many of these concepts together in a way that will be useful to architects. (shrink)

Two decades of social and political analysis have helped to enrich the concept of risk that underlies the bulk of modern environmental regulation. Risk is no longer seen merely as the probability of harm arising from more or less determinable physical, biological or social causes. Instead, it seems more appropriate to view risk as the embodiment of deeply held cultural values and beliefs – the songlines of the paper's title – concerning such issues as agency, causation, and uncertainty. (...) These values are incorporated into the formal methodologies, such as quantitative risk assessment, by which industrial societies assess risk. The meaning of risk accordingly varies from one cultural context to another, posing difficult problems for global environmental governance. The paper reflects on the role of science in promoting convergent perceptions of risk across disparate political cultures. (shrink)

Gene–environment covariance is the phenomenon whereby genetic differences bias variation in developmental environment, and is particularly problematic for assigning genetic and environmental causation in a heritability analysis. The interpretation of these cases has differed amongst biologists and philosophers, leading some to reject the utility of heritability estimates altogether. This paper examines the factors that influence causal reasoning when G–E covariance is present, leading to interpretive disagreement between scholars. It argues that the causal intuitions elicited are influenced by concepts (...) of agency and blame-worthiness, and are intimately tied with the conceptual understanding of the phenotype under investigation. By considering a phenotype-specific approach, I provide an account as to why causal ascriptions can differ depending on the interpreter. Phenotypes like intelligence, which have been the primary focus of this debate, are more likely to spark disagreement for the interpretation of G–E covariance cases because the concept and ideas about its ‘normal development’ relatively ill-defined and are a subject of debate. I contend that philosophical disagreement about causal attributions in G–E covariance cases are in essence disagreements regarding how a phenotype should be defined and understood. This moves the debate from one of an ontological flavour concerning objective causal claims, to one concerning the conceptual, normative and semantic dependencies. (shrink)

Causation has multiple distinct meanings in genetics. One reason for this is meaning slippage between two concepts of the gene: Mendelian and molecular. Another reason is that a variety of genetic methods address different kinds of causal relationships. Some genetic studies address causes of traits in individuals, which can only be assessed when single genes follow predictable inheritance patterns that reliably cause a trait. A second sense concerns the causes of trait differences within a population. Whereas some single genes (...) can be said to cause population-level differences, most often these claims concern the effects of many genes. Polygenic traits can be understood using heritability estimates, which estimate the relative influences of genetic and environmental differences to trait differences within a population. Attempts to understand the molecular mechanisms underlying polygenic traits have been developed, although causal inference based on these results remains controversial. Genetic variation has also recently been leveraged as a randomizing factor to identify environmental causes of trait differences. This technique—Mendelian randomization—offers some solutions to traditional epidemiological challenges, although it is limited to the study of environments with known genetic influences. (shrink)