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  1.  12
    The ‘Serious’ Factor in Germline Modification.Erika Kleiderman, Vardit Ravitsky & Bartha Maria Knoppers - 2019 - Journal of Medical Ethics 45 (8):508-513.
    Current advances in assisted reproductive technologies aim to promote the health and well-being of future children. They offer the possibility to select embryos with the greatest potential of being born healthy and may someday correct faulty genes responsible for heritable diseases in the embryo ). Most laws and policy statements surrounding HGGM refer to the notion of ‘serious’ as a core criterion in determining what genetic diseases should be targeted by these technologies. Yet, this notion remains vague and poorly defined, (...)
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  2.  6
    The Serious Factor in Expanded Prenatal Genetic Testing.Vardit Ravitsky, Anne-Marie Laberge, Marie-Christine Roy, Bartha Knoppers, Vasiliki Rahimzadeh & Erika Kleiderman - 2022 - American Journal of Bioethics 22 (2):23-25.
    Bayefsky and Berkman argue in favor of evidence-based policy development for expanded prenatal genetic testing. They propose to identify what kinds of information pregnant persons, their par...
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  3.  30
    Returning Incidental Findings From Genetic Research to Children: Views of Parents of Children Affected by Rare Diseases.Erika Kleiderman, Bartha Maria Knoppers, Conrad V. Fernandez, Kym M. Boycott, Gail Ouellette, Durhane Wong-Rieger, Shelin Adam, Julie Richer & Denise Avard - 2014 - Journal of Medical Ethics 40 (10):691-696.
  4.  7
    ‘Serious’ Factor—a Relevant Starting Point for Further Debate: A Response.Erika Kleiderman, Vardit Ravitsky & Bartha Maria Knoppers - 2020 - Journal of Medical Ethics 46 (2):153-155.
    In this reply, we wish to defend our original position and address several of the points raised by two excellent responses. The first response questions the relevance of the notion of ‘serious’ within the context of human germline genome modification. We argue that the ‘serious’ factor is relevant and that there is a need for medical and social lenses to delineate the limits of acceptability and initial permissible applications of HGGM. In this way, ‘serious’ acts as a starting point for (...)
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  5.  14
    Genetically Enhanced Minors: Whose Responsibility?Erika Kleiderman, Audrey Boily & Bartha Maria Knoppers - 2018 - American Journal of Bioethics 18 (6):1-3.
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  6.  4
    Re-Contact Following Withdrawal of Minors From Research.Dimitri Patrinos, Bartha Maria Knoppers, Erika Kleiderman, Noriyeh Rahbari, David P. Laplante & Ashley Wazana - 2022 - Canadian Journal of Bioethics / Revue canadienne de bioéthique 5 (1).
    Re-contacting minors enrolled in research upon their reaching the age of majority or maturity to seek their autonomous consent to continue their participation is considered an ethical requirement. This issue has generally been studied in the context of minors who are actively involved in the research. However, what becomes of this issue when the minor has been withdrawn from the research or has been lost to follow-up? May researchers re-contact the minor at the age of majority or maturity under these (...)
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  7. Recruiting Terminally Ill Patients Into Non-Therapeutic Oncology Studies: Views of Health Professionals. [REVIEW]Erika Kleiderman, Denise Avard, Lee Black, Zuanel Diaz, Caroline Rousseau & Bartha Knoppers - 2012 - BMC Medical Ethics 13 (1):33-.
    Background Non-therapeutic trials in which terminally ill cancer patients are asked to undergo procedures such as biopsies or venipunctures for research purposes, have become increasingly important to learn more about how cancer cells work and to realize the full potential of clinical research. Considering that implementing non-therapeutic studies is not likely to result in direct benefits for the patient, some authors are concerned that involving patients in such research may be exploitive of vulnerable patients and should not occur at all, (...)
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  8.  4
    The Impact of Reporting Magnetic Resonance Imaging Incidental Findings in the Canadian Alliance for Healthy Hearts and Minds Cohort.Rhian Touyz, Amy Subar, Ian Janssen, Bob Reid, Eldon Smith, Caroline Wong, Pierre Boyle, Jean Rouleau, F. Henriques, F. Marcotte, K. Bibeau, E. Larose, V. Thayalasuthan, A. Moody, F. Gao, S. Batool, C. Scott, S. E. Black, C. McCreary, E. Smith, M. Friedrich, K. Chan, J. Tu, H. Poiffaut, J. -C. Tardif, J. Hicks, D. Thompson, L. Parker, R. Miller, J. Lebel, H. Shah, D. Kelton, F. Ahmad, A. Dick, L. Reid, G. Paraga, S. Zafar, N. Konyer, R. de Souza, S. Anand, M. Noseworthy, G. Leung, A. Kripalani, R. Sekhon, A. Charlton, R. Frayne, V. de Jong, S. Lear, J. Leipsic, A. -S. Bourlaud, P. Poirier, E. Ramezani, K. Teo, D. Busseuil, S. Rangarajan, H. Whelan, J. Chu, N. Noisel, K. McDonald, N. Tusevljak, H. Truchon, D. Desai, Q. Ibrahim, K. Ramakrishnana, C. Ramasundarahettige, S. Bangdiwala, A. Casanova, L. Dyal, K. Schulze, M. Thomas, S. Nandakumar, B. -M. Knoppers, P. Broet, J. Vena, T. Dummer, P. Awadalla, Matthias G. Friedrich, Douglas S. Lee, Jean-Claude Tardif, Erika Kleiderman & Marcotte - 2021 - BMC Medical Ethics 22 (1).
    BackgroundIn the Canadian Alliance for Healthy Hearts and Minds cohort, participants underwent magnetic resonance imaging of the brain, heart, and abdomen, that generated incidental findings. The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants were recruited with (...)
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  9.  10
    Of the Rights and Best Interests of Future Generations.Erika Kleiderman, Minh Thu Nguyen & Bartha Maria Knoppers - 2020 - American Journal of Bioethics 20 (8):38-40.
    Volume 20, Issue 8, August 2020, Page 38-40.
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