In May 1999, David Lewis sent Timothy Williamson an intriguing letter about knowledge and vagueness. This paper has a brief discussion of Lewis on evidence, and a longer discussion of a distinctive theory of vagueness Lewis puts forward in this letter, one rather different from standard forms of supervaluationism. Lewis's theory enables him to provide distinctive responses to the challenges to supervaluationism famously offered in chapter 5 of Timothy Williamson's 1994 book Vagueness. However these responses bring out a number (...) of very surprising features of Lewis's own view. -/- The letter from Lewis itself is available on the blog of The Age of Metaphysical Revolution Project, University of Manchester. (shrink)

Assume that it is your evidence that determines what opinions you should have. I argue that since you should take peer disagreement seriously, evidence must have two features. (1) It must sometimes warrant being modest: uncertain what your evidence warrants, and (thus) uncertain whether you’re rational. (2) But it must always warrant being guided: disposed to treat your evidence as a guide. Surprisingly, it is very difficult to vindicate both (1) and (2). But diagnosing why this (...) is so leads to a proposal—Trust—that is weak enough to allow modesty but strong enough to yield many guiding features. In fact, I claim that Trust is the Goldilocks principle—for it is necessary and sufficient to vindicate the claim that you should always prefer to use free evidence. Upshot: Trust lays the foundations for a theory of disagreement and, more generally, an epistemology that permits self-doubt—a modest epistemology. (shrink)

Recent authors have drawn attention to a new kind of defeating evidence commonly referred to as higher-order evidence. Such evidence works by inducing doubts that one’s doxastic state is the result of a flawed process – for instance, a process brought about by a reason-distorting drug. I argue that accommodating defeat by higher-order evidence requires a two-tiered theory of justification, and that the phenomenon gives rise to a puzzle. The puzzle is that at least in some (...) situations involving higher-order defeaters the correct epistemic rules issue conflicting recommendations. For instance, a subject ought to believe p, but she ought also to suspend judgment in p. I discuss three responses. The first resists the puzzle by arguing that there is only one correct epistemic rule, an Über-rule. The second accepts that there are genuine epistemic dilemmas. The third appeals to a hierarchy or ordering of correct epistemic rules. I spell out problems for all of these responses. I conclude that the right lesson to draw from the puzzle is that a state can be epistemically rational or justified even if one has what looks to be strong evidence to think that it is not. As such, the considerations put forth constitute a non question-begging argument for a kind of externalism. (shrink)

Sometimes we get evidence of our own epistemic malfunction. This can come from finding out we’re fatigued, or have been drugged, or that other competent and well-informed thinkers disagree with our beliefs. This sort of evidence seems to seems to behave differently from ordinary evidence about the world. In particular, getting such evidence can put agents in a position where the most rational response involves violating some epistemic ideal.

In this influential study of central issues in the philosophy of science, Paul Horwich elaborates on an important conception of probability, diagnosing the failure of previous attempts to resolve these issues as stemming from a too-rigid conception of belief. Adopting a Bayesian strategy, he argues for a probabilistic approach, yielding a more complete understanding of the characteristics of scientific reasoning and methodology. Presented in a fresh twenty-first-century series livery, and including a specially commissioned preface written by Colin Howson, illuminating its (...) enduring importance and relevance to philosophical enquiry, this engaging work has been revived for a new generation of readers. (shrink)

In this paper, we argue for a particular informative and unified analysis of normative reasons. According to this analysis, a fact F is a reason to act in a certain way just in case it is evidence that one ought to act in that way. Similarly, F is a reason to believe a certain proposition just in case it is evidence for the truth of this proposition. Putting the relatively uncontroversial claim about reasons for belief to one side, (...) we present several arguments in favor of our analysis of reasons for action. We then turn to consider a series of objections to the analysis. We conclude that there are good reasons to accept the analysis and that the objections do not succeed. (shrink)

First-order evidence is evidence which bears on whether a proposition is true. Higher-order evidence is evidence which bears on whether a person is able to assess her evidence for or against a proposition. A widespread view is that higher-order evidence makes a difference to whether it is rational for a person to believe a proposition. In this paper, I consider in what way higher-order evidence might do this. More specifically, I consider whether and (...) how higher-order evidence plays a role in determining what it is rational to believe distinct from that which first-order evidence plays. To do this, I turn to the theory of reasons, and try to situate higher-order evidence within it. The only place I find for it there, distinct from that which first-order evidence already occupies, is as a practical reason, that is, as a reason for desire or action. One might take this to show either that the theory of reasons is inadequate as it stands or that higher-order evidence makes no distinctive difference to what it is rational to believe. I tentatively endorse the second option. (shrink)

There is something puzzling about statistical evidence. One place this manifests is in the law, where courts are reluctant to base affirmative verdicts on evidence that is purely statistical, in spite of the fact that it is perfectly capable of meeting the standards of proof enshrined in legal doctrine. After surveying some proposed explanations for this, I shall outline a new approach – one that makes use of a notion of normalcy that is distinct from the idea of (...) statistical frequency. The puzzle is not, however, merely a legal one. Our unwillingness to base beliefs on statistical evidence is by no means limited to the courtroom, and is at odds with almost every general principle that epistemologists have proposed as to how we ought to manage our beliefs. (shrink)

In everyday life and in science we acquire evidence of evidence and based on this new evidence we often change our epistemic states. An assumption underlying such practice is that the following EEE Slogan is correct: 'evidence of evidence is evidence' (Feldman 2007, p. 208). We suggest that evidence of evidence is best understood as higher-order evidence about the epistemic state of agents. In order to model evidence of evidence (...) we introduce a new powerful framework for modelling epistemic states, Dyadic Bayesianism. Based on this framework, we then discuss characterizations of evidence of evidence and argue for one of them. Finally, we show that whether the EEE Slogan holds, depends on the specific kind of evidence of evidence. (shrink)

WE AIM HERE to outline a theory of evidence for use. More specifically we lay foundations for a guide for the use of evidence in predicting policy effectiveness in situ, a more comprehensive guide than current standard offerings, such as the Maryland rules in criminology, the weight of evidence scheme of the International Agency for Research on Cancer (IARC), or the US ‘What Works Clearinghouse’. The guide itself is meant to be well-grounded but at the same time (...) to give practicable advice, that is, advice that can be used by policy-makers not expert in the natural and social sciences, assuming they are well-intentioned and have a reasonable but limited amount of time and resources available for searching out evidence and deliberating. (shrink)

The philosophy of evidence-based medicine -- What is EBM? -- What is good evidence for a clinical decision? -- Ruling out plausible rival hypotheses and confounding factors : a method -- Resolving the paradox of effectiveness : when do observational studies offer the same degree of evidential support as randomized trials? -- Questioning double blinding as a universal methodological virtue of clinical trials : resolving the Philip's paradox -- Placebo controls : problematic and misleading baseline measures of effectiveness (...) -- Questioning the methodological superiority of "placebo" over "active" controlled trials -- Examining the paradox that traditional roles for mechanistic reasoning and expert -- Judgment have been up-ended by EBM -- A qualified defence of the EBM stance on mechanistic reasoning -- Knowledge that versus knowledge how : situating the EBM position on expert clinical judgment -- Moving EBM forward. (shrink)

Medical scientists employ ‘quality assessment tools’ (QATs) to measure the quality of evidence from clinical studies, especially randomized controlled trials (RCTs). These tools are designed to take into account various methodological details of clinical studies, including randomization, blinding, and other features of studies deemed relevant to minimizing bias and error. There are now dozens available. The various QATs on offer differ widely from each other, and second-order empirical studies show that QATs have low inter-rater reliability and low inter-tool reliability. (...) This is an instance of a more general problem I call the underdetermination of evidential significance. Disagreements about the strength of a particular piece of evidence can be due to different—but in principle equally good—weightings of the fine-grained methodological features which constitute QATs. (shrink)

Evidence-based medicine (EBM) makes use of explicit procedures for grading evidence for causal claims. Normally, these procedures categorise evidence of correlation produced by statistical trials as better evidence for a causal claim than evidence of mechanisms produced by other methods. We argue, in contrast, that evidence of mechanisms needs to be viewed as complementary to, rather than inferior to, evidence of correlation. In this paper we first set out the case for treating (...) class='Hi'>evidence of mechanisms alongside evidence of correlation in explicit protocols for evaluating evidence. Next we provide case studies which exemplify the ways in which evidence of mechanisms complements evidence of correlation in practice. Finally, we put forward some general considerations as to how the two sorts of evidence can be more closely integrated by EBM. (shrink)

I argue that Descartes uses his method as evidence in the Discours and Les Météores. I begin by establishing there is a single method in Descartes’ works, using his meteorology as a case study. First, I hold that the method of the Regulae is best explained by two examples: one scientific, his proof of the anaclastic curve (1626), and one metaphysical, his question of the essence and scope of human knowledge (1628). Based on this account, I suggest that the (...) form of his early metaphysics (not its content) is similar to the method of doubt of the Meditationes. Second, I argue that Descartes’ explanation of the cause of parhelia (1629) likewise contains a formulation of this procedure. I provide a novel reading of Les Météores, where, following Descartes’ guidance in the Discours and Correspondance, I interpret his meteorology by reasoning from effects to causes, in this case, from Christoph Scheiner’s 1626 observation of parhelia to his meteorological foundation. This backwards orientation to Les Météores, I argue, reveals an instance of Descartes’ scientific method. I conclude with remarks on Descartes’ concept of evidentia, in which I explain how he incorporates a posteriori evidence and an apparent hypothetical foundation into his rationalist epistemology where he uses his method as evidence for his claims. (shrink)

Because few would object to evidence-based medicine’s (EBM) principal task of basing medical decisionmaking on the most judicious and up-to-date evidence, the debate over this prolific movement may seem puzzling. Who, one may ask, could be against evidence (Carr-Hill, 2006)? Yet this question belies the sophistication of the evidence-based movement. This chapter presents the evidence-based approach as a socio-medical phenomenon and seeks to explain and negotiate the points of disagreement between supporters and detractors. This is (...) done by casting EBM as more than the simple application of research findings to clinical care and improved health outcomes, but rather an umbrella term that harnesses a specific set of pedagogical objectives (some rather radical) under a name that makes it difficult to argue against. (shrink)

For many epistemologists, and for many philosophers more broadly, it is axiomatic that rationality requires you to take the doxastic attitudes that your evidence supports. Yet there is also another current in our talk about rationality. On this usage, rationality is a matter of the right kind of coherence between one's mental attitudes. Surprisingly little work in epistemology is explicitly devoted to answering the question of how these two currents of talk are related. But many implicitly assume that (...) class='Hi'>evidence -responsiveness guarantees coherence, so that the rational impermissibility of incoherence will just fall out of the putative requirement to take the attitudes that one's evidence supports, and so that coherence requirements do not need to be theorized in their own right, apart from evidential reasons. In this paper, I argue that this is a mistake, since coherence and evidence -responsiveness can in fact come into conflict. More specifically, I argue that in cases of misleading higher-order evidence, there can be a conflict between believing what one's evidence supports and satisfying a requirement that I call “inter-level coherence ”. This illustrates why coherence requirements and evidential reasons must be separated and theorized separately. (shrink)

I explore how rational belief and rational credence relate to evidence. I begin by looking at three cases where rational belief and credence seem to respond differently to evidence: cases of naked statistical evidence, lotteries, and hedged assertions. I consider an explanation for these cases, namely, that one ought not form beliefs on the basis of statistical evidence alone, and raise worries for this view. Then, I suggest another view that explains how belief and credence relate (...) to evidence. My view focuses on the possibilities that the evidence makes salient. I argue that this makes better sense of the difference between rational credence and rational belief than other accounts. (shrink)

Sherrilyn Roush defends a new theory of knowledge and evidence, based on the idea of "tracking" the truth, as the best approach to a wide range of questions about knowledge-related phenomena. The theory explains, for example, why scepticism is frustrating, why knowledge is power, and why better evidence makes you more likely to have knowledge. Tracking Truth provides a unification of the concepts of knowledge and evidence, and argues against traditional epistemological realist and anti-realist positions about scientific (...) theories and for a piecemeal approach based on a criterion of evidence, a position Roush calls "real anti-realism." Epistemologists and philosophers of science will recognize this as a significant original contribution. (shrink)

I argue that perceptual experience provides us with both phenomenal and factive evidence. To a first approximation, we can understand phenomenal evidence as determined by how our environment sensorily seems to us when we are experiencing. To a first approximation, we can understand factive evidence as necessarily determined by the environment to which we are perceptually related such that the evidence is guaranteed to be an accurate guide to the environment. I argue that the rational source (...) of both phenomenal and factive evidence lies in employing perceptual capacities that we have in virtue of being perceivers. In showing that both kinds of evidence have the same rational source, I provide a unified account of perceptual evidence and its rational source in perceptual experience. (shrink)

Here I criticise Audi's account of self-evidece. I deny that understanding of a proposition can justify belief in it and offfer an account of intuition that can take the place of understanding in an account of self-evidence.

Perceptions guide our actions and provide us with evidence of the world around us. Illusions and hallucinations can mislead us: they may prompt as to act in ways that do not mesh with the world around us and they may lead us to form false beliefs about that world. The capacity view provides an account of evidence that does justice to these two facts. It shows in virtue of what illusions and hallucinations mislead us and prompt us to (...) act. Moreover, it shows in virtue of what we are in a better epistemic position when we perceive than when we hallucination. In this paper, I develop the capacity view, that is, the view that perceptual experience has epistemic force in virtue of the epistemic and metaphysical primacy of the perceptual capacities employed in perception. By grounding the epistemic force of experience in facts about the metaphysical structure of experience, the capacity view is not only an externalist view, but moreover a naturalistic view of the epistemology of perceptual experience. So it is an externalist and naturalistic alternative to reliabilism. I discuss the repercussions of this view for the justification of beliefs and the epistemic transparency of mental states, as well as, familiar problem cases. (shrink)

My aim in this paper is to develop and defend a novel answer to a question that has recently generated a considerable amount of controversy. The question concerns the normative significance of peer disagreement. Suppose that you and I have been exposed to the same evidence and arguments that bear on some proposition: there is no relevant consideration which is available to you but not to me, or vice versa. For the sake of concreteness, we might picture.

The problem of evil is the most prominent argument against the existence of God. Skeptical theists contend that it is not a good argument. Their reasons for this contention vary widely, involving such notions as CORNEA, epistemic appearances, 'gratuitous' evils, 'levering' evidence, and the representativeness of goods. We aim to dispel some confusions about these notions, in particular by clarifying their roles within a probabilistic epistemology. In addition, we develop new responses to the problem of evil from both the (...) phenomenal conception of evidence and the knowledge-first view of evidence. (shrink)

Plausibly, you should believe what your total evidence supports. But cases of misleading higher-order evidence—evidence about what your evidence supports—present a challenge to this thought. In such cases, taking both first-order and higher-order evidence at face value leads to a seemingly irrational incoherence between one’s first-order and higher-order attitudes: you will believe P, but also believe that your evidence doesn’t support P. To avoid sanctioning tension between epistemic levels, some authors have abandoned the thought (...) that both first-order and higher-order evidence have rational bearing. This sacrifice is both costly and unnecessary. We propose a principle, Evidential Calibration, which requires rational agents to accommodate first-order evidence correctly, while allowing rational uncertainty about what to believe. At the same time, it rules out irrational tensions between epistemic levels. We show that while there are serious problems for some views on which we can rationally believe, “P, but my evidence doesn’t support P”, Evidential Calibration avoids these problems. An important upshot of our discussion is a new way to think about the relationship between epistemic levels: why first-order and higher-order attitudes should generally be aligned, and why it is sometimes—though not always—problematic when they diverge. (shrink)

Evidence-based medicine (EBM) has thus far failed to adequately account for the appropriate incorporation of other potential warrants for medical decision making into clinical practice. In particular, EBM has struggled with the value and integration of other kinds of medical knowledge, such as those derived from clinical experience or based on pathophysiologic rationale. The general priority given to empirical evidence derived from clinical research in all EBM approaches is not epistemically tenable. A casuistic alternative to EBM approaches recognizes (...) that five distinct topics, 1) empirical evidence, 2) experiential evidence, 3) pathophysiologic rationale, 4) patient goals and values, and 5) system features are potentially relevant to any clinical decision. No single topic has a general priority over any other and the relative importance of a topic will depend upon the circumstances of the particular case. The skilled clinician must weigh these potentially conflicting evidentiary and non-evidentiary warrants for action, employing both practical and theoretical reasoning, in order to arrive at the best choice for an individual patient. (shrink)

Begins by explaining then proving a generalized language dependence result similar to Goodman's "grue" problem. I then use this result to cast doubt on the existence of an objective evidential favoring relation (such as "the evidence confirms one hypothesis over another," "the evidence provides more reason to believe one hypothesis over the other," "the evidence justifies one hypothesis over the other," etc.). Once we understand what language dependence tells us about evidential favoring, our options are an implausibly (...) strong conception of the a priori, a hard externalism on which agents are unable to determine what their evidence favors, or a subjectivist view that makes evidential favoring relative to features of the agent. (shrink)

Evidentialism is the thesis that a person is justified in believing a proposition iff the person's evidence on balance supports that proposition. In discussing epistemological issues associated with disagreements among epistemic peers, some philosophers have endorsed principles that seem to run contrary to evidentialism, specifying how one should revise one's beliefs in light of disagreement. In this paper, I examine the connection between evidentialism and these principles. I argue that the puzzles about disagreement provide no reason to abandon evidentialism (...) and that there are no true general principles about justified responses to disagreement other than the general evidentialist principle. I then argue that the puzzles about disagreement are primarily puzzles about the evidential impact of higher - order evidence – evidence about the significance or existence of ordinary, or first- order, evidence. I conclude by arguing that such higher - order evidence can often have a profound effect on the justification of first- order beliefs. (shrink)

What is required for something to be evidence for a hypothesis? In this fascinating, elegantly written work, distinguished philosopher of science Peter Achinstein explores this question, rejecting typical philosophical and statistical theories of evidence. He claims these theories are much too weak to give scientists what they want--a good reason to believe--and, in some cases, they furnish concepts that mistakenly make all evidential claims a priori. Achinstein introduces four concepts of evidence, defines three of them by reference (...) to "potential" evidence, and characterizes the latter using a novel epistemic interpretation of probability. The resulting theory is then applied to philosophical and historical issues. Solutions are provided to the "grue," "ravens," "lottery," and "old-evidence" paradoxes, and to a series of questions. These include whether explanations or predictions furnish more evidential weight, whether individual hypotheses or entire theoretical systems can receive evidential support, what counts as a scientific discovery, and what sort of evidence is required for it. The historical questions include whether Jean Perrin had non-circular evidence for the existence of molecules, what type of evidence J. J. Thomson offered for the existence of the electron, and whether, as is usually supposed, he really discovered the electron. Achinstein proposes answers in terms of the concepts of evidence introduced. As the premier book in the fabulous new series Oxford Studies in Philosophy of Science, this volume is essential for philosophers of science and historians of science, as well as for statisticians, scientists with philosophical interests, and anyone curious about scientific reasoning. (shrink)

In recent years a growing number of philosophers writing about the methodology of philosophy have defended the surprising claim that philosophers do not use intuitions as evidence. In this paper I defend the contrary view that philosophers do use intuitions as evidence. I argue that this thesis is the best explanation of several salient facts about philosophical practice. First, philosophers tend to believe propositions which they find intuitive. Second, philosophers offer error theories for intuitions that conflict with their (...) theories. Finally, philosophers are more confident in rejecting theories to the extent that they have several counter examples involving diverse cases. I argue that these facts are better explained by philosophers' using intuitions as evidence than by any plausible contrary explanations. I further argue that aspects of philosophical practice that my thesis may initially seem ill-suited to explain are in fact unsurprising whether or not my thesis is true. (shrink)

Many people have recently argued that we need to distinguish between experiences and seemings and that this has consequences for views about how perception provides evidence. In this article I spell out my take on these issues by doing three things. First, I distinguish between mere sensations like seeing pitch black all around you and perceptual experiences like seeing a red apple. Both have sensory phenomenology in presenting us with sensory qualities like colors, being analog in Dretske's sense, and (...) being fine-grained. However, only the latter have furthermore a perceptual phenomenology characterized by objectification and related dualities of perspectivality/completion and variation/constancy. Second, I elaborate on the reasons for thinking that both mere sensations and perceptual experiences need to be distinguished from accompanying seemings that passively assign things into conceptual categories and thereby tell you something about them. For example, when you look at a red apple and have the relevant recognitional abilities it will also normally seem to you that this is an apple. Finally, I argue that the best version of the popular dogmatist view about evidence is one which claims that it's neither experiences nor seemings by themselves, but rather the right sorts of composites of experiences and seemings that provide evidence. (shrink)

It is still a live question in epistemology and philosophy of science as to what exactly evidence is. In my view, evidence consists in experiences called “seemings.” This view is a version of the phenomenal conception of evidence, the position that evidence consists in nonfactive mental states with propositional content. This conception is opposed by sense-data theorists, disjunctivists, and those who think evidence consists in physical objects or publicly observable states of affairs—call it the courtroom (...) conception of evidence. Thomas Kelly has recently argued that the phenomenal conception cannot play all the roles evidence plays and is thus inadequate. Having first explained the nature of seemings, in this essay I utilize Kelly’s own understanding of the four major roles of evidence and argue that the phenomenal conception can play each one. Experience is a good candidate for evidence. (shrink)

Conciliatory views of disagreement maintain that discovering a particular type of disagreement requires that one make doxastic conciliation. In this paper I give a more formal characterization of such a view. After explaining and motivating this view as the correct view regarding the epistemic significance of disagreement, I proceed to defend it from several objections concerning higher-order evidence made by Thomas Kelly.

Conspiracy theories are often portrayed as unwarranted beliefs, typically supported by suspicious kinds of evidence. Yet contemporary work in Philosophy argues provisional belief in conspiracy theories is at the very least understandable---because conspiracies occur---and that if we take an evidential approach, judging individual conspiracy theories on their particular merits, belief in such theories turns out to be warranted in a range of cases. -/- Drawing on this work, I examine the kinds of evidence typically associated with conspiracy theories, (...) and show how the so-called evidential problems with conspiracy theories are also problems for the kinds of evidence put forward in support of other theories. As such, if there is a problem with the conspiracy theorist's use of evidence, it is one of principle: is the principle which guides the conspiracy theorist's use of evidence somehow in error? I argue that whatever we might think about conspiracy theories generally, there is no prima facie case for a scepticism of conspiracy theories based purely on their use of evidence. (shrink)

An astonishing volume and diversity of evidence is available for many hypotheses in the biomedical and social sciences. Some of this evidence—usually from randomized controlled trials (RCTs)—is amalgamated by meta-analysis. Despite the ongoing debate regarding whether or not RCTs are the ‘gold-standard’ of evidence, it is usually meta-analysis which is considered the best source of evidence: meta-analysis is thought by many to be the platinum standard of evidence. However, I argue that meta-analysis falls far short (...) of that standard. Different meta-analyses of the same evidence can reach contradictory conclusions. Meta-analysis fails to provide objective grounds for intersubjective assessments of hypotheses because numerous decisions must be made when performing a meta-analysis which allow wide latitude for subjective idiosyncrasies to influence its outcome. I end by suggesting that an older tradition of evidence in medicine—the plurality of reasoning strategies appealed to by the epidemiologist Sir Bradford Hill—is a superior strategy for assessing a large volume and diversity of evidence. (shrink)

The law views with suspicion statistical evidence, even evidence that is probabilistically on a par with direct, individual evidence that the law is in no way suspicious of. But it has proved remarkably hard to either justify this suspicion, or to debunk it. In this paper, we connect the discussion of statistical evidence to broader epistemological discussions of similar phenomena. We highlight Sensitivity – the requirement that a belief be counterfactually sensitive to the truth in a (...) specific way – as a way of epistemically explaining the legal suspicion towards statistical evidence. Still, we do not think of this as a satisfactory vindication of the reluctance to rely on statistical evidence. Knowledge – and Sensitivity, and indeed epistemology in general – are of little, if any, legal value. Instead, we tell an incentive-based story vindicating the suspicion towards statistical evidence. We conclude by showing that the epistemological story and the incentive-based story are closely and interestingly related, and by offering initial thoughts about the role of statistical evidence in morality. (shrink)

Obviously medicine should be evidence-based. The issues lie in the details: what exactly counts as evidence? Do certain kinds of evidence carry more weight than others? And how exactly should medicine be based on evidence? When it comes to these details, the evidence-based medicine movement has got itself into a mess – or so it will be argued. In order to start to resolve this mess, we need to go 'back to basics'; and that means (...) turning to the philosophy of science. The theory of evidence, or rather the logic of the interrelations between theory and evidence, has always been central to the philosophy of science – sometimes under the alias of the 'theory of confirmation'. When taken together with a little philosophical commonsense, this logic can help us move towards a position on evidence in medicine that is more sophisticated and defensible than anything that EBM has been able so far to supply. (shrink)

“Absence of evidence isn’t evidence of absence” is a slogan that is popular among scientists and nonscientists alike. This article assesses its truth by using a probabilistic tool, the Law of Likelihood. Qualitative questions (“Is E evidence about H ?”) and quantitative questions (“How much evidence does E provide about H ?”) are both considered. The article discusses the example of fossil intermediates. If finding a fossil that is phenotypically intermediate between two extant species provides (...) class='Hi'>evidence that those species have a common ancestor, does failing to find such a fossil constitute evidence that there was no common ancestor? Or should the failure merely be chalked up to the imperfection of the fossil record? The transitivity of the evidence relation in simple causal chains provides a broader context, which leads to discussion of the fine-tuning argument, the anthropic principle, and observation selection effects. (shrink)

Reasoning from negative evidence takes place where an expected outcome is tested for, and when it is not found, a conclusion is drawn based on the significance of the failure to find it. By using Gricean maxims and implicatures, we show how a set of alternatives, which we call a paradigm, provides the deep inferential structure on which reasoning from lack of evidence is based. We show that the strength of reasoning from negative evidence depends on how (...) the arguer defines his conclusion and what he considers to be in the paradigm of negated alternatives. If we negate only two of the several possible alternatives, even if they are the most probable, the conclusion will be weak. However, if we deny all possible alternatives, the reasoning will be strong, and even in some cases deductively valid. (shrink)

According to factive accounts of the norm of belief and decision-making, you should not believe or base decisions on a falsehood. Even when the evidence misleadingly suggests that a false proposition is true, you should not believe it or base decisions on it. Critics claim that factive accounts are counterintuitive and badly mischaracterize our ordinary practice of evaluating beliefs and decisions. This paper reports four experiments that rigorously test the critic’s accusations and the viability of factive accounts. The results (...) undermine the accusations and provide the best evidence yet of factive norms of belief and decision-making. The results also help discriminate between two leading candidates for a factive norm: truth and knowledge. Knowledge is the superior candidate. (shrink)

In order to perform certain actions – such as incarcerating a person or revoking parental rights – the state must establish certain facts to a particular standard of proof. These standards – such as preponderance of evidence and beyond reasonable doubt – are often interpreted as likelihoods or epistemic confidences. Many theorists construe them numerically; beyond reasonable doubt, for example, is often construed as 90 to 95% confidence in the guilt of the defendant. -/- A family of influential cases (...) suggests standards of proof should not be interpreted numerically. These ‘proof paradoxes’ illustrate that purely statistical evidence can warrant high credence in a disputed fact without satisfying the relevant legal standard. In this essay I evaluate three influential attempts to explain why merely statistical evidence cannot satisfy legal standards. (shrink)

We claim that if a complete philosophy of evidence-based practice is intended, then attention to the nature of causation in health science is necessary. We identify how health science currently conceptualises causation by the way it prioritises some research methods over others. We then show how the current understanding of what causation is serves to constrain scientific progress. An alternative account of causation is offered. This is one of dispositionalism. We claim that by understanding causation from a dispositionalist stance, (...) many of the processes within an evidence-based practice framework are better accounted for. Further, some of the problems associated with the health research, e.g. external validity of causal findings, dissolve. (shrink)

Even though the evidence‐based medicine movement (EBM) labels mechanisms a low quality form of evidence, consideration of the mechanisms on which medicine relies, and the distinct roles that mechanisms might play in clinical practice, offers a number of insights into EBM itself. In this paper, I examine the connections between EBM and mechanisms from several angles. I diagnose what went wrong in two examples where mechanistic reasoning failed to generate accurate predictions for how a dysfunctional mechanism would respond (...) to intervention. I then use these examples to explain why we should expect this kind of mechanistic reasoning to fail in systematic ways, by situating these failures in terms of evolved complexity of the causal system(s) in question. I argue that there is still a different role in which mechanisms continue to figure as evidence in EBM: namely, in guiding the application of population‐level recommendations to individual patients. Thus, even though the evidence‐based movement rejects one role in which mechanistic reasoning serves as evidence, there are other evidentiary roles for mechanistic reasoning. This renders plausible the claims of some critics of evidencebased medicine who point to the ineliminable role of clinical experience. Clearly specifying the ways in which mechanisms and mechanistic reasoning can be involved in clinical practice frames the discussion about EBM and clinical experience in more fruitful terms. (shrink)

Proponents of evidence-based medicine have argued convincingly for applying this scientific method to medicine. However, the current methodological framework of the EBM movement has recently been called into question, especially in epidemiology and the philosophy of science. The debate has focused on whether the methodology of randomized controlled trials provides the best evidence available. This paper attempts to shift the focus of the debate by arguing that clinical reasoning involves a patchwork of evidential approaches and that the emphasis (...) on evidence hierarchies of methodology fails to lend credence to the common practice of corroboration in medicine. I argue that the strength of evidence lies in the evidence itself, and not the methodology used to obtain that evidence. Ultimately, when it comes to evaluating the effectiveness of medical interventions, it is the evidence obtained from the methodology rather than the methodology that should establish the strength of the evidence. (shrink)

In this paper, I argue against the epistemology of some contemporary moral intuitionists who believe that the notion of self-evidence is more important than that of intuition. Quite the contrary, I think the notion of intuition is more basic if intuitions are construed as intellectual seemings. First, I will start with elaborating Robert Audi’s account of self-evidence. Next, I criticise his account on the basis of the idea of “adequate understanding”. I shall then present my alternative account of (...) self-evidence which is based on the seeming account of intuition. Finally, I show how the seeming account of self-evidence can make the moral intuitionist epistemology more tenable. (shrink)

Cancer research is experiencing ‘paradigm instability’, since there are two rival theories of carcinogenesis which confront themselves, namely the somatic mutation theory and the tissue organization field theory. Despite this theoretical uncertainty, a huge quantity of data is available thanks to the improvement of genome sequencing techniques. Some authors think that the development of new statistical tools will be able to overcome the lack of a shared theoretical perspective on cancer by amalgamating as many data as possible. We think instead (...) that a deeper understanding of cancer can be achieved by means of more theoretical work, rather than by merely accumulating more data. To support our thesis, we introduce the analytic view of theory development, which rests on the concept of plausibility, and make clear in what sense plausibility and probability are distinct concepts. Then, the concept of plausibility is used to point out the ineliminable role played by the epistemic subject in the development of statistical tools and in the process of theory assessment. We then move to address a central issue in cancer research, namely the relevance of computational tools developed by bioinformaticists to detect driver mutations in the debate between the two main rival theories of carcinogenesis. Finally, we briefly extend our considerations on the role that plausibility plays in evidence amalgamation from cancer research to the more general issue of the divergences between frequentists and Bayesians in the philosophy of medicine and statistics. We argue that taking into account plausibility-based considerations can lead to clarify some epistemological shortcomings that afflict both these perspectives. (shrink)

Should people include beef in their diet? This chapter argues that the answer is “no” by reviewing what is known and not known about the presence in cattle of three psychological traits: pain, desire, and self-consciousness. On the basis of behavioral and neuroanatomical evidence, the chapter argues that cattle are sentient beings who have things they want to do in the proximal future, but they are not self-conscious. The piece rebuts three important objections: that cattle have injury information but (...) not pain; that cattle have goal-directed behavior but not desire; and that the absence of evidence for bovine self-consciousness should not be taken as evidence that cattle lack self-consciousness. In sum, what is known about cattle cognition shifts the moral burden of proof on to the beef eaters. (shrink)

Recent attempts to resolve the Paradox of the Gatecrasher rest on a now familiar distinction between individual and bare statistical evidence. This paper investigates two such approaches, the causal approach to individual evidence and a recently influential (and award-winning) modal account that explicates individual evidence in terms of Nozick's notion of sensitivity. This paper offers counterexamples to both approaches, explicates a problem concerning necessary truths for the sensitivity account, and argues that either view is implausibly committed to (...) the impossibility of no-fault wrongful convictions. The paper finally concludes that the distinction between individual and bare statistical evidence cannot be maintained in terms of causation or sensitivity. We have to look elsewhere for a solution of the Paradox of the Gatecrasher. (shrink)

In this paper, I shall discuss a problem that arises when you try to combine an attractive account of what constitutes evidence with an independently plausible account of the kind of access we have to our evidence. According to E = K, our evidence consists of what we know. According to the principle of armchair access, we can know from the armchair what our evidence is. Combined, these claims entail that we can have armchair knowledge of (...) the external world. Because it seems that the principle of armchair access is supported by widely shared intuitions about epistemic rationality, it seems we ought to embrace an internalist conception of evidence. I shall argue that this response is mistaken. Because externalism about evidence can accommodate the relevant intuitions about epistemic rationality, the principle of armchair access is unmotivated. We also have independent reasons for preferring externalism about evidence to the principle of armchair access. (shrink)