59 found
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  1. Principles for Allocation of Scarce Medical Interventions.Govind Persad, Alan Wertheimer & Ezekiel J. Emanuel - 2009 - The Lancet 373 (9661):423--431.
    Allocation of very scarce medical interventions such as organs and vaccines is a persistent ethical challenge. We evaluate eight simple allocation principles that can be classified into four categories: treating people equally, favouring the worst-off, maximising total benefits, and promoting and rewarding social usefulness. No single principle is sufficient to incorporate all morally relevant considerations and therefore individual principles must be combined into multiprinciple allocation systems. We evaluate three systems: the United Network for Organ Sharing points systems, quality-adjusted life-years, and (...)
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  2.  46
    The Oxford Textbook of Clinical Research Ethics.Ezekiel J. Emanuel (ed.) - 2008 - Oxford University Press.
    Comprehensive in scope and research, this book will be a crucial resource for researchers in the medical sciences, as well as teachers and students alike.
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  3.  28
    Undue Inducement: Nonsense on Stilts?Ezekiel J. Emanuel - 2005 - American Journal of Bioethics 5 (5):9-13.
    1. The opinions expressed are the author's own. They do not reflect any position or policy of the National Institutes of Health, Public Health Service, Department of Health and Human Services, or any of the authors affiliated organizations.
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  4.  40
    Exploitation and Developing Countries: The Ethics of Clinical Research.Jennifer S. Hawkins & Ezekiel J. Emanuel - 2008 - Princeton Univ Pr.
    "--Daniel Wikler, Harvard School of Public Health "This book contributes significantly to the literature on exploitation in clinical research conducted in the developing world."--Patricia Marshall, Case Western Reserve University.
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  5. The Ethics of Research on Enhancement Interventions.Lev Ori, G. Miller Franklin & J. Emanuel Ezekiel - 2010 - Kennedy Institute of Ethics Journal 20 (2):101-113.
    Traditionally, biomedical research has been devoted to improvement in the understanding and treatment or prevention of disease. Building on the knowledge generated by the long history of disease-oriented research, the next few decades will witness an explosion of biomedical enhancements to make people faster, stronger, smarter, less forgetful, happier, prettier, and live longer (Turner et al. 2003; Vastag 2004; Rose 2002). As with other biomedical interventions, research to assess the safety and efficacy of these enhancements in humans should be conducted (...)
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  6. Ethical and Regulatory Aspects of Clinical Research: Readings and Commentary.Ezekiel J. Emanuel (ed.) - 2003 - Johns Hopkins University Press.
    All investigators funded by the National Institutes of Health are now required to receive training about the ethics of clinical research. Based on a course taught by the editors at NIH, Ethical and Regulatory Aspects of Clinical Research is the first book designed to help investigators meet this new requirement. The book begins with the history of human subjects research and guidelines instituted since World War II. It then covers various stages and components of the clinical trial process: designing the (...)
     
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  7.  24
    Ending Concerns About Undue Inducement.Ezekiel J. Emanuel - 2004 - Journal of Law, Medicine & Ethics 32 (1):100-105.
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  8.  18
    Clinical Research: Should Patients Pay to Play?Ezekiel J. Emanuel, Steven Joffe, Christine Grady, David Wendler & Govind Persad - 2015 - Science Translational Medicine 7 (298):298ps16.
    We argue that charging people to participate in research is likely to undermine the fundamental ethical bases of clinical research, especially the principles of social value, scientific validity, and fair subject selection.
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  9.  20
    The Ends of Human Life: Medical Ethics in a Liberal Polity.Ezekiel J. Emanuel - 1991 - Harvard University Press.
    INTRODUCTION The Questions of Medical Ethics Call him Andrew. His face is gaunt and unshaven but peaceful. His eyelids are gently closed. ...
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  10. What is the Great Benefit of Legalizing Euthanasia or Physican‐Assisted Suicide?Ezekiel J. Emanuel - 1999 - Ethics 109 (3):629-642.
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  11.  90
    The Current State of Medical School Education in Bioethics, Health Law, and Health Economics.Govind C. Persad, Linden Elder, Laura Sedig, Leonardo Flores & Ezekiel J. Emanuel - 2008 - Journal of Law, Medicine & Ethics 36 (1):89-94.
    Current challenges in medical practice, research, and administration demand physicians who are familiar with bioethics, health law, and health economics. Curriculum directors at American Association of Medical Colleges-affiliated medical schools were sent confidential surveys requesting the number of required hours of the above subjects and the years in which they were taught, as well as instructor names. The number of relevant publications since 1990 for each named instructor was assessed by a PubMed search.In sum, teaching in all three subjects combined (...)
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  12.  61
    Clarifying Confusions About Coercion.Jennifer Susan Hawkins & Ezekiel J. Emanuel - 2005 - Hastings Center Report 35 (5):16-19.
    Commentators often claim that medical research subjects are coerced into participating in clinical studies. In recent years, such claims have appeared especially frequently in ethical discussions of research in developing countries. Medical research ethics is more important than ever as we move into the 21st century because worldwide the pharmaceutical industry has grown so much and shows no sign of slowing its growth. This means that more people are involved in medical research today than ever before, and in the future (...)
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  13. 10. Uma Narayan, Dislocating Cultures: Identities, Traditions, and Third World Feminism Uma Narayan, Dislocating Cultures: Identities, Traditions, and Third World Feminism (Pp. 668-671). [REVIEW]Judith Jarvis Thomson, Dan W. Brock, Paul J. Weithman, Gerald Dworkin, F. M. Kamm, J. David Velleman & Ezekiel J. Emanuel - 1999 - Ethics 109 (3).
  14.  34
    What Are Bioethicists.Ezekiel J. Emanuel - 2008 - Hastings Center Report 38 (2).
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  15. Standing by Our Principles: Meaningful Guidance, Moral Foundations, and Multi-Principle Methodology in Medical Scarcity.Govind C. Persad, Alan Wertheimer & Ezekiel J. Emanuel - 2010 - American Journal of Bioethics 10 (4):46 – 48.
    In this short response to Kerstein and Bognar, we clarify three aspects of the complete lives system, which we propose as a system of allocating scarce medical interventions. We argue that the complete lives system provides meaningful guidance even though it does not provide an algorithm. We also defend the investment modification to the complete lives system, which prioritizes adolescents and older children over younger children; argue that sickest-first allocation remains flawed when scarcity is absolute and ongoing; and argue that (...)
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  16.  6
    An Ethical Framework for Biomedical Research.Ezekiel J. Emanuel, David Wendler & C. Grady - 2008 - In The Oxford Textbook of Clinical Research Ethics. Oxford University Press. pp. 123--135.
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  17.  23
    The Ethics of Expanding Access to Cheaper, Less Effective Treatments.Govind C. Persad & Ezekiel J. Emanuel - 2016 - The Lancet:S0140-6736(15)01025-9.
    This article examines a fundamental question of justice in global health. Is it ethically preferable to provide a larger number of people with cheaper treatments that are less effective (or more toxic), or to restrict treatments to a smaller group to provide a more expensive but more effective or less toxic alternative? We argue that choosing to provide less effective or more toxic interventions to a larger number of people is favored by the principles of utility, equality, and priority for (...)
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  18.  16
    The Current State of Medical School Education in Bioethics, Health Law, and Health Economics.Govind C. Persad, Linden Elder, Laura Sedig, Leonardo Flores & Ezekiel J. Emanuel - 2008 - Journal of Law, Medicine and Ethics 36 (1):89-94.
    This study reviews the amount of attention bioethics, health law, and health economics receive in medical school curricula and the background of professors teaching these topic. It concludes that the number of required hours of instruction in bioethics, health law, and health economics in medical schools comprises less than two percent of the medical school curriculum; that time on these subjects is heavily weighted toward the first two years of medical education; and that many instructors have not published on the (...)
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  19.  68
    The Problem with Single-Payer Plans.Ezekiel J. Emanuel - 2008 - Hastings Center Report 38 (1):38-41.
  20.  8
    Protecting Communities in Research: Current Guidelines and Limits of Extrapolation.Charles Weijer, Gary Goldsand & Ezekiel J. Emanuel - unknown
    As genetic research increasingly focuses on communities, there have been calls for extending research protections to them. We critically examine guidelines developed to protect aboriginal communities and consider their applicability to other communities. These guidelines are based on a model of researcher-community partnership and span the phases of a research project, from protocol development to publication. The complete list of 23 protections may apply to those few non-aboriginal communities, such as the Amish, that are highly cohesive. Although some protections may (...)
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  21.  49
    Improving Access to Health Care: A Consensus Ethical Framework to Guide Proposals for Reform.Mark A. Levine, Matthew K. Wynia, Paul M. Schyve, J. Russell Teagarden, David A. Fleming, Sharon King Donohue, Ron J. Anderson, James Sabin & Ezekiel J. Emanuel - 2007 - Hastings Center Report 37 (5):14-19.
  22.  3
    Justice and Managed Care: Four Principles for the Just Allocation of Health Care Resources.Ezekiel J. Emanuel - 2000 - Hastings Center Report 30 (3):8-16.
  23. Ending Concerns About Undue Inducement.Ezekiel J. Emanuel - 2004 - Journal of Law, Medicine and Ethics 32 (1):100-105.
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  24.  29
    Four Paradigms of Clinical Research and Research Oversight.Ezekiel J. Emanuel & Christine Grady - 2006 - Cambridge Quarterly of Healthcare Ethics 16 (1):82-96.
    The understanding of appropriate ethical protections for participants of biomedical research has not been static. It has evolved over time, with the evolution of biomedical research as well as social values. Since World War II, there have been four major paradigms of research and research oversight operative in the United States. These paradigms incorporate different values and provide different approaches to research oversight and the protection of research participants.
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  25.  6
    Dilemmas in Access to Medicines: A Humanitarian Perspective – Authors' Reply.Ezekiel J. Emanuel & Govind Persad - 2017 - Lancet 387 (10073):1008-1009.
    Our Viewpoint argues that expanding access to less effective or more toxic treatments is supported not only by utilitarian ethical reasoning but also by two other ethical frameworks: those that emphasise equality and those that emphasise giving priority to the patients who are worst off. The inadequate resources available for global health reflect not only natural constraints but also unwise social and political choices. However, pitting efforts to reduce inequality and better fund global health against efforts to put available resources (...)
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  26.  5
    Conserving Scarce Resources: Willingness of Health Insurance Enrollees to Choose Cheaper Options.Samia A. Hurst, J. Russell Teagarden, Elizabeth Garrett & Ezekiel J. Emanuel - 2004 - Journal of Law, Medicine & Ethics 32 (3):496-499.
  27.  3
    Medical Ethics in the Era of Managed Care: The Need for Institutional Structures Instead of Principles for Individual Cases.Ezekiel J. Emanuel - 1995 - Journal of Clinical Ethics 6 (4):335.
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  28.  24
    Empirical Studies on Euthanasia and Assisted Suicide.Ezekiel J. Emanuel - 1995 - Journal of Clinical Ethics 6 (2):158-160.
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  29. The Evolving Norms of Medical Ethics.Ezekiel J. Emanuel - 2008 - In Ronald Michael Green, Aine Donovan & Steven A. Jauss (eds.), Global Bioethics: Issues of Conscience for the Twenty-First Century. Oxford University Press.
     
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  30.  9
    Tiers Without Tears: The Ethics of a Two-Tiered Health Care System.Benjamin J. Krohmal & Ezekiel J. Emanuel - 2009 - In Bonnie Steinbock (ed.), The Oxford Handbook of Bioethics. Oxford University Press.
    American health care reformers face a number of ethical issues, including familiar debates over the merits of a single-payer system and publicly provided universal health insurance. No matter how these debates are resolved, a further ethical question must be addressed. Both universal coverage and a single-payer system are compatible with permitting some patients to pay more for faster, better, or more health care choices. Should the United States continue to have a two-tier health care system in which wealth grants some (...)
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  31.  3
    The Beinning of the End of Principlism.Ezekiel J. Emanuel - 1995 - Hastings Center Report 25 (4):37-38.
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  32.  2
    Decisions at the End of Life.Linda L. Emanuel & Ezekiel J. Emanuel - 1993 - Hastings Center Report 23 (5):6-14.
  33.  2
    Informed Consent: Practices and Views of Investigators in a Multinational Clinical Trial.Lindsay Sabik, Christine A. Pace, Heidi P. Forster-Gertner, David Wendler, Judith D. Bebchuk, Jorge A. Tavel, Laura A. McNay, Jack Killen, Ezekiel J. Emanuel & Christine Grady - 2004 - IRB: Ethics & Human Research 27 (5):13-18.
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  34.  25
    Living Wills: Past, Present, and Future.Ezekiel J. Emanuel & Linda L. Emanuel - 1990 - Journal of Clinical Ethics 1 (1):9.
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  35. Conserving Scarce Resources: Willingness of Health Insurance Enrollees to Choose Cheaper Options.Samia A. Hurst, J. Russell Teagarden, Elizabeth Garrett & Ezekiel J. Emanuel - 2004 - Journal of Law, Medicine and Ethics 32 (3):496-499.
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  36.  1
    A Communal Vision of Care for Incompetent Patients.Ezekiel J. Emanuel - 1987 - Hastings Center Report 17 (5):15-20.
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  37.  14
    Carl E. Schneider is the Chauncey.Ezekiel J. Emanuel - forthcoming - Hastings Center Report.
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  38. The Concept of Conflicts of Interest.Ezekiel J. Emanuel & Dennis F. Thompson - 2008 - In The Oxford Textbook of Clinical Research Ethics. Oxford University Press. pp. 758--766.
     
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  39.  5
    Where Civic Republicanism and Deliberative Democracy Meet.Ezekiel J. Emanuel - 1996 - Hastings Center Report 26 (6):12-14.
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  40.  21
    The Blossoming of Bioethics at NIH.Ezekiel J. Emanuel - 1998 - Kennedy Institute of Ethics Journal 8 (4):455-466.
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  41.  8
    Prescribing Our Future: Ethical Challenges in Genetic Counseling (Book).Ezekiel J. Emanuel - 1994 - Ethics and Behavior 4 (1):69 – 73.
  42.  7
    Is Longer Always Better?Ezekiel J. Emanuel, Christine Grady & Jerry Menikoff - 2008 - Hastings Center Report 38 (3):10.
  43.  15
    What Are Bioethicists Doing About Health Care Reform?Ezekiel J. Emanuel - 2008 - Hastings Center Report 38 (2):12-13.
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  44.  12
    Response to Commentators on “Undue Inducement: Nonsense on Stilts?”.Ezekiel J. Emanuel - 2005 - American Journal of Bioethics 5 (5):W8-W11.
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  45.  10
    Protecting Communities in Research: From a New Principle to Rational Protections.Ezekiel J. Emanuel & Charles Weijer - unknown
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  46.  3
    Research Oversight Through New Lenses: The Consortium to Examine Clinical Research Ethics.Jeremy Sugarman, Lisa A. Eckenwiler & Ezekiel J. Emanuel - 2002 - IRB: Ethics & Human Research 25 (1):9-10.
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  47.  3
    Living Wills: Are Durable Powers of Attorney Better?Ezekiel J. Emanuel - 2004 - Hastings Center Report 34 (6):5.
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  48.  6
    Commentary.Ezekiel J. Emanuel & Christine Grady - 2008 - Hastings Center Report 38 (3):10-12.
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  49.  2
    Case Study: Is Longer Always Better?Ezekiel J. Emanuel, Christine Grady & Jerry Menikoff - forthcoming - Hastings Center Report.
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  50.  6
    Book Review. [REVIEW]Ezekiel J. Emanuel - 1994 - Ethics and Behavior 4 (1):69 – 73.
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