In May 1968, Gilles Deleuze was an established philosopher teaching at the innovative Vincennes University, just outside of Paris. Felix Guattari was a political militant and director of an unusual psychiatric clinic at La Borde. Their meeting was unlikely, and the two were introduced in an arranged encounter of epic consequence. From that moment on, Deleuze and Guattari engaged in a surprising, productive partnership, collaborating on several groundbreaking works, including Anti-Oedipus, What Is Philosophy? and A Thousand Plateaus. Francois Dosse, a (...) prominent French intellectual, examines the prolific, if improbable, relationship between two men of distinct and differing sensibilities. Drawing on unpublished archives and hundreds of personal interviews, Dosse elucidates a collaboration that lasted more than two decades, underscoring the role that family and history--particularly the turbulence of May 1968--played in their monumental work. He also takes the measure of Deleuze and Guattari's posthumous fortunes and weighs the impact of their thought within intellectual, academic, and professional circles. (shrink)
We investigate how a uniformly rotating frame is defined as the rest frame of an observer rotating with constant angular velocity Ω around the z axis of an inertial frame. Assuming this frame to be a Lorentz one, we second quantize a free massless scalar field in the rotating frame and obtain that creation-annihilation operators of the field are not the same as those of an inertial frame. This leads to a new vacuum state—a rotating vacuum. After this, introducing an (...) apparatus device coupled linearly with the field, we obtain that there is a strong correlation between the number of Trocheries-Takeno particles (in a given state) obtained via canonical quantization and the response function of the rotating detector. Finally, we analyze polarization effects in circular accelerators in the proper frame of the electron, making a connection with the inertial frame point of view. (shrink)
The review presents the International Workshop “Transcendental Turn in Contemporary Philosophy-3: Nature of Transcendental Philosophy” held in Moscow on 19-22 April, 2018. The workshop was co-sponsored by the State Academic University for the Humanities, the Russian State University for the Humanities and the Foundation for the Humanities. The review examines the main topics of the workshop, summarises the main presentations and explicates the problem area of modern interpretations of Kant and the development of transcendentalism in the twentieth and twenty-first centuries. (...) The presentations, questions and discussions centred around the main problems of transcendentalism: the differences between the phenomenon and the thing in itself, between the first and second editions of the Critique of Pure Reason, the relationship between realist and constructivist aspects of Kantian transcendentalism, the transformation of Kantian transcendental philosophy in Neo-Kantianism and phenomenology and more. (shrink)
This text is a bilingual Arabic-English translation of one of the most important metaphysical works of the Persian Muslim philosopher known as Mulla Sadra & Sadr al-Din Muhammad al-Shirazi. In this work Mulla Sadra develops an anti-Platonic philosophical position which is non-Aristotelian. He holds that "existents" are ontologically prior to "essence" & that there are two different realms -- the mind dependent domain & entities which exist independent of the mind. Mulla Sadra's views became very popular among Iranian Muslim philosophers (...) & eventually were instrumental in destroying the Aristotelian school of thought in the Islamic world. The translator, Dr. Parviz Morewedge, is the Secretary-Treasurer of the Society for the Study of Islamic Philosophy & Science & has published ten books & numerous articles in Islamic Philosophy & Mysticism. (shrink)
Advances in technology are bringing greater insight into the mind, raising a host of privacy concerns. However, the basic psychological mechanisms underlying the perception of privacy violations are poorly understood. Here, we explore the relation between the perception of privacy violations and access to information related to one’s “self.” In two studies using demographically diverse samples, we find that privacy violations resulting from various monitoring technologies are mediated by the extent to which the monitoring is thought to provide access to (...) self-relevant information, and generally neuromonitoring did not rate among the more invasive monitoring types. However, brain monitoring was judged to be more of a privacy violation when described as providing access to self-relevant information than when no such access was possible, and control participants did not judge the invasiveness of neuromonitoring any differently than those told it provided no access to self-relevant information. (shrink)
Spade 1988 sugges t s tha t t he r e are ac tua l l y two theo r i e s t o address t h i s ques t i o n t o , an ear l y one and a l a t e r one . 2 Most o f the presen t pape r i s a deve l o pmen t o f t h i s i dea . I sugges t (...) tha t ear l y work by Sherwood and o the r s was a s tudy o f quan t i f i e r s : the i r semant i c s and t he e f f e c t s o f con t e x t on i n f e r e n ce s t ha t can be made f r om quan t i f i e d te rms . La te r , i n the hands o f Bur l e y and o the r s , i t changed i n t o a s tudy o f someth i n g e l se , a s tudy o f what I ca l l g loba l quan t i f i c a t i o n a l e f f e c t . In sec t i o n 1 , I exp l a i n what these two op t i o n s are. (shrink)
The sporadic nature of Alzheimer's disease argues for an environmental link that may drive AD pathogenesis; however, the triggering factors and the period of their action are unknown. Recent studies in rodents have shown that exposure to lead during brain development predetermined the expression and regulation of the amyloid precursor protein and its amyloidogenic beta-amyloid product in old age. Here, we report that the expression of AD-related genes [APP, BACE1 ] as well as their transcriptional regulator were elevated in aged (...) monkeys exposed to Pb as infants. Furthermore, developmental exposure to Pb altered the levels, characteristics, and intracellular distribution of Abeta staining and amyloid plaques in the frontal association cortex. These latent effects were accompanied by a decrease in DNA methyltransferase activity and higher levels of oxidative damage to DNA, indicating that epigenetic imprinting in early life influenced the expression of AD-related genes and promoted DNA damage and pathogenesis. These data suggest that AD pathogenesis is influenced by early life exposures and argue for both an environmental trigger and a developmental origin of AD. (shrink)
Many lymphokine genes have now been cloned from activated T cells and their products have been expressed in mammalian cells. Use of these recombinant lymphokines has provided the opportunity to evaluate both the spectrum of their biological activities and the mechanisms of their action in promoting proliferation and differentiation of hemopoietic and lymphoid cells. Characterization of the structure of lymphokine genes will provide information about their regulated expression in T‐cell activation.