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  1.  37
    Obtaining Informed Consent for Genomics Research in Africa: Analysis of H3Africa Consent Documents.Nchangwi Syntia Munung, Patricia Marshall, Megan Campbell, Katherine Littler, Francis Masiye, Odile Ouwe-Missi-Oukem-Boyer, Janet Seeley, D. J. Stein, Paulina Tindana & Jantina de Vries - 2016 - Journal of Medical Ethics 42 (2):132-137.
  2.  9
    “I Passed the Test!” Evidence of Diagnostic Misconception in the Recruitment of Population Controls for an H3Africa Genomic Study in Cape Town, South Africa.Francis Masiye, Bongani Mayosi & Jantina de Vries - 2017 - BMC Medical Ethics 18 (1):12.
    Advances in genetic and genomic research have introduced challenges in obtaining informed consent for research in low and middle-income settings. However, there are only few studies that have explored challenges in obtaining informed consent in genetic and genomic research in Africa and none in South Africa. To start filling this gap, we conducted an empirical study to investigate the efficacy of informed consent procedures for an H3Africa genomic study on Rheumatic Heart Disease at the University of Cape Town in South (...)
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  3.  72
    Improving Understanding of Clinical Trial Procedures Among Low Literacy Populations: An Intervention Within a Microbicide Trial in Malawi. [REVIEW]Paul M. Ndebele, Douglas Wassenaar, Esther Munalula & Francis Masiye - 2012 - BMC Medical Ethics 13 (1):29-.
    Background The intervention reported in this paper was a follow up to an empirical study conducted in Malawi with the aim of assessing trial participants’ understanding of randomisation, double-blinding and placebo use. In the empirical study, the majority of respondents (61.1%; n= 124) obtained low scores (lower than 75%) on understanding of all three concepts under study. Based on these findings, an intervention based on a narrative which included all three concepts and their personal implications was designed. The narrative used (...)
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  4.  30
    Is It Ethical to Prevent Secondary Use of Stored Biological Samples and Data Derived From Consenting Research Participants? The Case of Malawi.Randy G. Mungwira, Wongani Nyangulu, James Misiri, Steven Iphani, Ruby Ng’ong’ola, Chawanangwa M. Chirambo, Francis Masiye & Joseph Mfutso-Bengo - 2015 - BMC Medical Ethics 16 (1):1-7.
    BackgroundThis paper discusses the contentious issue of reuse of stored biological samples and data obtained from research participants in past clinical research to answer future ethical and scientifically valid research questions. Many countries have regulations and guidelines that guide the use and exportation of stored biological samples and data. However, there are variations in regulations and guidelines governing the reuse of stored biological samples and data in Sub-Saharan Africa including Malawi.DiscussionThe current research ethics regulations and guidelines in Malawi do not (...)
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  5. Toward an African Ubuntu/Umunthu Bioethics in Malawi in the Context of Globalization.Joseph Mfutso-Bengo & Francis Masiye - 2011 - In Catherine Myser (ed.), Bioethics Around the Globe. Oxford University Press.
  6.  65
    Hiv/Aids Reduces the Relevance of the Principle of Individual Medical Confidentiality Among the Bantu People of Southern Africa.Paul Ndebele, Joseph Mfutso-Bengo & Francis Masiye - 2008 - Theoretical Medicine and Bioethics 29 (5):331-340.
    The principle of individual medical confidentiality is one of the moral principles that Africa inherited unquestioningly from the West as part of Western medicine. The HIV/AIDS pandemic in Southern Africa has reduced the relevance of the principle of individual medical confidentiality. Individual medical confidentiality has especially presented challenges for practitioners among the Bantu communities that are well known for their social inter-connectedness and the way they value their extended family relations. Individual confidentiality has raised several unforeseen problems for persons living (...)
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  7.  68
    Ethical Aspects of Hiv/Aids Prevention Strategies and Control in Malawi.Joseph-Matthew Mfutso-Bengo, Eva-Maria Mfutso-Bengo & Francis Masiye - 2008 - Theoretical Medicine and Bioethics 29 (5):349-356.
    HIV/AIDS prevention campaigns have been overshadowed by conflicting, competing, and contradictory views between those who support condom use as a last resort and those who are against it for fear of promoting sexual immorality. We argue that abstinence and faithfulness to one partner are the best available moral solutions to the HIV/AIDS pandemic. Of course, deontologists may argue that condom use might appear useful and effective in controlling HIV/AIDS; however, not everything that is useful is always good. In principle, all (...)
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  8.  77
    Routine Third Party Disclosure of Hiv Results to Identifiable Sexual Partners in Sub-Saharan Africa.Francis Masiye & Robert Ssekubugu - 2008 - Theoretical Medicine and Bioethics 29 (5):341-348.
    The challenges of dealing with disclosure of HIV status cause frustration to health care providers and counselors. This frustration follows from the already known high risk to the third party on one hand and our ethical obligation to “respect persons” in terms of privacy and confidentiality on the other side. Given the stubbornly low rates of voluntary disclosure (partner notification) among couples, however, it is quite tempting to suggest a paradigm of routine third party disclosure to identifiable sexual partners by (...)
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  9.  4
    A Qualitative Study Exploring Stakeholder Perspectives on the Use of Biological Samples for Future Unspecified Research in Malawi.Limbanazo Matandika, Ruby Tionenji Ngóngóla, Khama Mita, Lucinda Manda-Taylor, Kate Gooding, Daniel Mwale, Francis Masiye & Joseph Mfutso-Bengo - 2020 - BMC Medical Ethics 21 (1):1-10.
    BackgroundThere is growing interest in the collection, storage and reuse of biological samples for future research. Storage and future use of biological samples raise ethical concerns and questions about approaches that safeguard the interests of participants. The situation is further complicated in Africa where there is a general lack of governing ethical frameworks that could guide the research community on appropriate approaches for sample storage and use. Furthermore, there is limited empirical data to guide development of such frameworks. A qualitative (...)
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