Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

The phenomenon of size constancy is defined as the apparent perceptual invariance of the linear dimensions of a seen object as this approaches the eye or recedes from it. It has been interpreted as resulting from the application by the brain of a size correction, made possible by the subject's apprehension of distance cues present in the image. We present several observations which, by dissociating accommodation from distance of the seen object and by suppressing the optic effects of accommodation on (...) the visual image itself, show that this interpretation is incorrect, and that in fact the size correction of the visual image is a function of the central effort of accommodation, not of the distance of the seen object. (shrink)

If I say “we are now living in England” or “grass is green in summer’ or ‘the cat is on the mat’ what I say will normally be true or false—the statements are true if they correctly report how things are, or correspond to the facts; and if they do not do these things, they are false. Such a statement will only fail to have a truth-value if its referring expressions fail to refer ; or if the statement lies on (...) the border between truth and falsity so that it is as true to say that the statement is true as to say that it is false. Are moral judgments normally true or false in the way in which the above statements are true or false? I will term the view that they are objectivism and the view that they are not subjectivism. The objectivist maintains that it is as much a fact about an action that it is right or wrong as that it causes pain or takes a long time to perform. The subjectivist maintains that saying than an action is right or wrong is not stating a fact about it but merely expressing approval of it or commending it or doing some such similar thing. I wish in this paper, first, to show that all arguments for subjectivism manifestly fail, and secondly to produce a strong argument for objectivism. But, to start with, some preliminaries. (shrink)

Ancient glacial sediments form major hydrocarbon plays in several parts of the world; most notably, North Africa, Latin America, and the Middle East. We have described a methodology for reconstructing broad-scale paleogeographies in just such a depositional system, using an extensive subsurface data set from the uppermost Ordovician glacial sediments of the Murzuq Basin of southwest Libya. Our workflow begins with the analysis of a large, high-quality 3D seismic data set, to understand the frequency content. Subsequently, optimum frequency bands are (...) extracted, after applying spectral decomposition, and then recombined into an R G B blended cube. This volume is then treated as an image within which paleomorphological features can be distinguished and compared with modern glacial analogs. Mapping at different depths of these features is then tied, by integration with core and image-log sedimentology, to specific depositional environments defined within the framework of a facies scheme developed using the well data and published outcrop studies. These depositional environments are extrapolated into areas with little or no well data using the spectral decomposition as a framework, always taking into account the significant difference in vertical resolution between the seismic data set and core-scale descriptions. The result of this methodology is a set of calibrated maps, at three different time depths, indicating paleogeographic reconstructions of the glacial depositional environments in the study area and the evolution through time of these glacial settings. (shrink)

On what grounds will the rational man become a Christian? It is often assumed by many, especially non-Christians, that he will become a Christian if and only if he judges that the evidence available to him shows that it is more likely than not that the Christian theological system is true, that, in mathematical terms, on the evidence available to him, the probability of its truth is greater than half. It is the purpose of this paper to investigate whether or (...) not this is a necessary and sufficient condition for the rational man to adopt Christianity. (shrink)

Although the widespread use of the term “Big Data” is comparatively recent, it invokes a phenomenon in the developments of database technology with distinct historical contexts. The database engineer Jim Gray, known as “Mr. Database” in Silicon Valley before his disappearance at sea in 2007, was involved in many of the crucial developments since the 1970s that constitute the foundation of exceedingly large and distributed databases. Jim Gray was involved in the development of relational database systems based on the concepts (...) of Edgar F. Codd at IBM in the 1970s before he went on to develop principles of Transaction Processing that enable the parallel and highly distributed performance of databases today. He was also involved in creating forums for discourse between academia and industry, which influenced industry performance standards as well as database research agendas. As a co-founder of the San Francisco branch of Microsoft Research, Gray increasingly turned toward scientific applications of database technologies, e. g. leading the TerraServer project, an online database of satellite images. Inspired by Vannevar Bush’s idea of the memex, Gray laid out his vision of a Personal Memex as well as a World Memex, eventually postulating a new era of data-based scientific discovery termed “Fourth Paradigm Science”. This article gives an overview of Gray’s contributions to the development of database technology as well as his research agendas and shows that central notions of Big Data have been occupying database engineers for much longer than the actual term has been in use. (shrink)

The eme r gence of the concept of pr o g ress is cu r rent l y associated with th e Enlightenment o r , going som e w hat further back, with the que r elle des anciens et des modernes in the 1 7 t h centu r y . Y et the notion of pr o g ress can be traced back to a signi f icant l y earlier period: the foundations of a possi b (...) le Christian pr o g ress i vism w ere, in m y opinion, laid b y St. Augustine; this ess a y e xplores its guidelines. J . G. Herde r ' s reaction a g ainst the notion of pr o g ress proposed b y the Enlightenment possesses also a Christian inspiration. While Enlightened pr o g ress i vism conce i v es past cultures as o v ercoming steps in a rising staircase, Herde r , in turn, claims that each of them amounted to a "self-centered sphere" and w as therefore v alua b le in its o wn right. The sense of the e xistence of past generations cannot lie in p a ving the w a y for future ful f illment as this w ould be incompati b le with d i vine l o v e, w hich estimates each of its creatures in its o wn right, as an unrepeata b le ind i vidual. In contrast to Enlightened a r r o g ance (contempt for the "obscurantist" past), Herder presents a "democratic" vi e w of History within w hich all epochs h a v e the same v alue. (shrink)

An alleged moral right to informational privacy assumes that we should have control over information about ourselves. What is the philosophical justification for this control? I think that one prevalent answer to this question—an answer that has to do with the justification of negative rights generally—will not do.

Mr Olding's recent attack on my exposition of the argument from design gives me an opportunity to defend the central theses of my original article. My article pointed out that there were arguments from design of two types—those which take as their premisses regularities of copresence and those which take as their premisses regularities of succession. I sought to defend an argument of the second type. One merit of such an argument is that there is no doubt about the truth (...) of its premisses. Almost all objects in the world behave in a highly regular way describable by scientific laws. Further, any scientific explanation of such a regularity must invoke some more general regularity. The most general regularities of all are, as such, scientifically inexplicable. The question arises whether there is a possible explanation of another kind which can be provided for them, and whether their occurrence gives any or much support to that explanation. I urged that we do explain some phenomena by explanation of an entirely different kind from the scientific. We explain states of affairs by the action of agents who bring them about intentionally of their own choice. Regularities of succession, as well as other phenomena may be explained in this way. Explanation of this kind I will term intentional explanation. Intentional explanation of some phenomenon E consists in adducing an agent A who brought E about of his own choice and a further end G which, he believed, would be forwarded by the production of E. (shrink)

The object of this paper is to examine what evidence we can have for or against the truth of determinism, a doctrine often set forward by the proposition ‘every event has a cause’. I understand in this context by the cause of an event a set of prior conditions jointly sufficient for the occurrence of the event. Since the determinist is concerned with all physical states and not merely with changes of states, which are most naturally termed events, we may (...) phrase this claim more precisely as follows: There is for every physical state at some earlier instant a set of conditions jointly sufficient for its occurrence. (shrink)

The most common view of suicide today is that it is intentional self-killing. 1 Because of the self-killing component, suicide is often described as self-inflicted death or as dying by one's own hand, and the victim is in turn often described as having done himself to death or as having taken his own life. But must one's death be self-inflicted in order to be suicide? The answer, I want to suggest, is arguably no.

In Ethics and the Limits of Philosophy, Bernard Williams is rather severe on what he thinks of as an ethics of obligation. He has in mind by this Kant and W. D. Ross. For many, obligation seems the very core of ethics and the moral realm, and lives more generally are seen through the prism of this notion. This, according to Williams, flattens out our lives and moral experience and fails to take into account things which are obviously important to (...) our lives. Once we take these things into account, what do we do if they come into conflict with some of our moral obligations, as Williams, in his earlier writings on moral luck, thought to be the case. I want here to explore some of these ideas, in a way that I think harmonious with Williams's general bent though not one that I intend as in any way detailed exegesis of Williams's work. (shrink)

The book, volume 42 in the Boston Studies in the Philosophy of Science, consists principally of two interconnected essays in theoretical biology. The first, entitled "Biology of Cognition," was written in 1969 by Humberto R. Maturana, a Chilean neurophysiologist and anatomist whose earlier work included studies of vision in birds and the frog. The second essay, "Autopoiesis: the Organization of the Living," is an expansion of certain sections in the first and was written in 1972 by Maturana and Francisco (...) J. Varela, a philosophical biologist. Although Maturana alone is responsible for the introduction, the two essays are said to represent one point of view, expressed in the concept of "autopoiesis." The term, "a word without a history," was invented to convey "the central feature of the organization of the living, which is autonomy". Autopoiesis, it is claimed, enables us to say at once, through the logic of a self-referring homeostatic system, what is organic life and cognition. "Living systems are cognitive systems, and living as a process is a process of cognition". (shrink)

Arguments move from premises to conclusions. The premises state things taken temporally for granted; if the argument works, the premises provide grounds for affirming the conclusion. A valid deductive argument is one in which the premises necessitate, that is, entail, the conclusion. What I shall call a ‘correct’ inductive argument is one in which the premises in some degree probabilify the conclusion, but do not necessitate it. More precisely, in what I shall call a correct P -inductive argument the premises (...) make the conclusion probable ; in what I shall call a correct C -inductive argument, the premises add to the probability of the conclusion . Arguments only show their conclusions to be true if they start from true premises; arguments of the above types which work and do start from such premises I will call sound arguments. Arguments are only of use to show to an individual that the conclusion is true if he already knows the premises to be true. Most of what I shall have to say today concerns arguments with respect to which there is no doubt that the premises are true. (shrink)

This treatise on aesthetics criticizes various psychological theories of art, offers new theories and interpretations, and draws important inferences concerning ...

This early work by Robin G. Collingwood was originally published in 1939 and we are now republishing it with a brand new introductory biography. 'An Autobiography' is the story of Collingwood's personal and academic life. Robin George Collingwood was born on 22nd February 1889, in Cartmel, England. He was the son of author, artist, and academic, W. G. Collingwood. He was greatly influenced by the Italian Idealists Croce, Gentile, and Guido de Ruggiero. Another important influence was his father, a professor (...) of fine art and a student of Ruskin. He published many works of philosophy, such as Speculum Mentis (1924), An Essay on Philosophic Method (1933), and An Essay on Metaphysics (1940). (shrink)

In this article we show that it is possible to completely classify the degrees of r.e. bases of r.e. vector spaces in terms of weak truth table degrees. The ideas extend to classify the degrees of complements and splittings. Several ramifications of the classification are discussed, together with an analysis of the structure of the degrees of pairs of r.e. summands of r.e. spaces.

R.G. Collingwood defined historical knowledge as essentially ‘scientific’, and saw the historian's task as the ‘re-enactment of past thoughts’. The author argues the need to go beyond Collingwood, first by demonstrating the authenticity of available evidence, and secondly, using Namier as an example, by considering methodology as well as epistemology, and the need to relate past thoughts to their present context. The ‘law of the consumption of time’ encourages historians to focus on landmark events, theories and generalisations, thus breaking from (...) Collingwood's emphasis on fidelity to past ideas and interpreting the past from the concepts of the present. This conflict can only be reconciled by the study of historiography. (shrink)

R.G. Collingwood defined historical knowledge as essentially ‘scientific’, and saw the historian's task as the ‘re-enactment of past thoughts’. The author argues the need to go beyond Collingwood, first by demonstrating the authenticity of available evidence, and secondly, using Namier as an example, by considering methodology as well as epistemology, and the need to relate past thoughts to their present context. The ‘law of the consumption of time’ encourages historians to focus on landmark events, theories and generalisations, thus breaking from (...) Collingwood's emphasis on fidelity to past ideas and interpreting the past from the concepts of the present. This conflict can only be reconciled by the study of historiography. (shrink)

2014 Reprint of 1945 Edition. Full facsimile of the original edition, not reproduced with Optical Recognition Software. The first part deals with Greek cosmology and is the longest, the most elaborate and, on the whole, the liveliest part of a book which never deviates into dullness. The dominant thought in Greek cosmology, Collingwood holds, was the microcosm-macrocosm analogy, nature being the substance of something ensouled where "soul" meant the self-moving. Part II is "The Renaissance View of Nature ." Collingwood describes (...) the rise and decline of the deists' view of Nature as a machine designed by the Great Contriver who, having turned it out, watches it go. Part III, "The Modern View of Nature," deals with very recent or contemporary philosophy and science, discerning in it a radical evolutionism first in biology and later in cosmology. Remains to this day a classic text in the history of ideas. (shrink)

EMPIRICIST THEORIES OF PERSONAL IDENTITY STATE THAT THE IDENTITY OF A PERSON OVER TIME IS A MATTER OF BODILY CONTINUITY AND/OR SIMILARITY OF MEMORY AND CHARACTER. IN CONTRAST, THIS PAPER ARGUES THAT WHILE BODILY CONTINUITY AND SIMILARITY OF MEMORY AND CHARACTER ARE EVIDENCE OF PERSONAL IDENTITY, THEY DO NOT CONSTITUTE IT. IT IS SOMETHING UNDEFINABLE. THE DIFFICULTY OF KNOWING WHAT TO SAY IN PUZZLE CASES DOES NOT SHOW THAT PERSONAL IDENTITY EXISTS IN DIFFERENT DEGREES OR THAT WE HAVE TO MAKE (...) ARBITRARY JUDGMENTS ABOUT IT. IT SHOWS ONLY THAT SOMETIMES WE CANNOT KNOW WHO IS WHO. (shrink)