Results for 'Gene Johnson'

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  1.  7
    To 'Gene Talk' (1992).Phillip Johnson - 1994 - Social Epistemology 8 (2):215 – 217.
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  2. Pathways to Consciousness: The Thalamus as the Brains's Switching Centre.Gene Johnson - 2004 - Science and Consciousness Review 2004.
  3.  47
    Socrates and Alcibiades - M. Johnson, H. Tarrant Alcibiades and the Socratic Lover-Educator. Pp. X + 254, Figs. London: Bristol Classical Press, 2012. Cased, £50. Isbn: 978-0-7156-4086-9. [REVIEW]David Johnson - 2013 - The Classical Review 63 (1):58-60.
  4.  30
    Reconsidering the Ad Hominem: Christopher M. Johnson.Christopher M. Johnson - 2009 - Philosophy 84 (2):251-266.
    Ad hominem arguments are generally dismissed on the grounds that they are not attempts to engage in rational discourse, but are rather aimed at undermining argument by diverting attention from claims made to assessments of character of persons making claims. The manner of this dismissal however is based upon an unlikely paradigm of rationality: it is based upon the presumption that our intellectual capacities are not as limited as in fact they are, and do not vary as much as they (...)
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  5. Book Excerpt: Computer Ethics, Second Edition by Deborah G. Johnson.Deborah G. Johnson - 1993 - Acm Sigcas Computers and Society 23 (3-4):10-14.
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  6. Darwinism Defeated? The Johnson-Lamoureux Debate on Biological Origins.Phillip E. Johnson, Denis Oswald Lamoureux & Michael J. Behe - 1999
     
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  7.  45
    Endnotes for Johnson, From Page 8.David K. Johnson - 1991 - Inquiry: Critical Thinking Across the Disciplines 8 (4):27-27.
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  8.  56
    Book Excerpt: Computer Ethics, by Deborah G. Johnson (Prentice Hall, 1994).Deborah G. Johnson - 1993 - Acm Sigcas Computers and Society 23 (3-4):10-14.
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  9. A Rebuttal to Dzur and Levin: Johnson on the Legitimacy and Authority of Bioethics Commissions.Summer Johnson - 2007 - Kennedy Institute of Ethics Journal 17 (2):143.
     
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  10.  50
    Samuel Johnson on Ireland.Samuel Johnson - 2003 - The Chesterton Review 29 (1/2):254-256.
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  11.  33
    Byzantine Egypt: Economic Studies. By A. C. Johnson and L. C. West. Pp. Viii + 344. London: Geoffrey Cumberlege: Princeton University Press, 1949. 27s. 6d. [REVIEW]A. H. M. Jones, A. C. Johnson & L. C. West - 1951 - Journal of Hellenic Studies 71:271-272.
  12.  68
    Paul Johnson Wonders Whether Darwin Would Have Put Atheist Slogans on Buses.Paul Johnson - 2009 - The Chesterton Review 35 (1/2):284-288.
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  13.  28
    Hartshorne's Arguments Against Empirical Evidence for Necessary Existence: An Evaluation: GALEN A. JOHNSON.Galen A. Johnson - 1977 - Religious Studies 13 (2):175-187.
    Is experiential evidence irrelevant to acceptance or rejection of belief in the existence of a Divine Being? Charles Hartshorne answers that it is indeed irrelevant, and this answer has an initial and, for me, continuing surprising ring to it. Specifically, Hartshorne makes two distinguishable claims: the traditional allegedly a posteriori arguments, the teleological and cosmological, are in fact incompatible with empiricist methodology and are disguised ontological arguments; the conception of God as necessary being demands that belief in such a being's (...)
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  14.  22
    Aesthetic Objectivity and the Analogy with Ethics: Oliver Johnson.Oliver Johnson - 1972 - Royal Institute of Philosophy Supplement 6:165-181.
    Of all the kinds of arguments that philosophers use to support their conclusions, the one type that I find personally to stick longest and most vividly in my mind is the verbal pictures they occasionally draw. Whether this is a result of the fact that I myself think best in pictorial terms or, as I would rather like to believe, is a tribute to the verbal artistry of the writers themselves, it remains true that, for me, the history of philosophy (...)
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  15.  11
    An Interview with Sonia Johnson.Karen S. Langlois & Sonia Johnson - 1982 - Feminist Studies 8 (1):6.
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  16.  38
    Comment by James Turner Johnson.James Turner Johnson - 2000 - Journal of Religious Ethics 28 (2):331-335.
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  17.  19
    Response to Laidlaw-Johnson.Paul F. Johnson - unknown
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  18.  6
    The Farwell Collection . By F. P. Johnson. Pp. Viii + 76, with 90 Figures. Cambridge, Mass: Archaeological Institute of America, 1953. Price Not Stated. [REVIEW]John Bradford & F. P. Johnson - 1955 - Journal of Hellenic Studies 75:187-187.
  19. Beyond Sense and Sensibility: Moral Formation and the Literary Imagination From Johnson to Wordsworth.Rhona Brown, Leslie A. Chilton, Timothy Erwin, Evan Gottlieb, Christopher D. Johnson, Heather King, James Noggle, Adam Rounce & Adrianne Wadewitz - 2014 - Bucknell University Press.
    Drawing on philosophical thought from the eighteenth century as well as conceptual frameworks developed in the twenty-first century, the essays in Beyond Sense and Sensibility examine moral formation as represented in or implicitly produced by literary works of late eighteenth-century British authors.
     
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  20. Alexander Bryan Johnson's a Treatise on Language, Ed.Alexander Bryan Johnson - 1947 - Berkeley: Univ. Of California Press.
  21. Alexander Bryan Johnson a Treatise on Language.A. B. Johnson - 1947 - Univ. Of California Press.
     
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  22. A.B. Johnson's a Treatise on Language or, the Relation Which Words Bear to Things.A. B. Johnson & Stillman Drake - 1940 - [S.N.].
     
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  23.  85
    The Moral Imperative to Continue Gene Editing Research on Human Embryos.Julian Savulescu, Jonathan Pugh, Thomas Douglas & Chris Gyngell - 2015 - Protein Cell 6 (7):476–479.
    The publication of the first study to use gene editing techniques in human embryos (Liang et al., 2015) has drawn outrage from many in the scientific community. The prestigious scientific journals Nature and Science have published commentaries which call for this research to be strongly discouraged or halted all together (Lanphier et al., 2015; Baltimore et al., 2015). We believe this should be questioned. There is a moral imperative to continue this research.
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  24. On the Application of Formal Principles to Life Science Data: A Case Study in the Gene Ontology.Jacob Köhler, Anand Kumar & Barry Smith - 2004 - In Proceedings of DILS 2004 (Data Integration in the Life Sciences), (Lecture Notes in Bioinformatics 2994). Berlin: Springer. pp. 79-94.
    Formal principles governing best practices in classification and definition have for too long been neglected in the construction of biomedical ontologies, in ways which have important negative consequences for data integration and ontology alignment. We argue that the use of such principles in ontology construction can serve as a valuable tool in error-detection and also in supporting reliable manual curation. We argue also that such principles are a prerequisite for the successful application of advanced data integration techniques such as ontology-based (...)
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  25.  58
    Is Mitochondrial Donation Germ‐Line Gene Therapy? Classifications and Ethical Implications.J. Newson Ainsley & Wrigley Anthony - 2017 - Bioethics 31 (1):55-67.
    The classification of techniques used in mitochondrial donation, including their role as purported germ-line gene therapies, is far from clear. These techniques exhibit characteristics typical of a variety of classifications that have been used in both scientific and bioethics scholarship. This raises two connected questions, which we address in this paper: how should we classify mitochondrial donation techniques?; and what ethical implications surround such a classification? First, we outline how methods of genetic intervention, such as germ-line gene therapy, (...)
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  26. Re-Examining the Gene in Personalized Genomics.Jordan Bartol - 2013 - Science & Education 22 (10):2529-2546.
    Personalized genomics companies (PG; also called ‘direct-to-consumer genetics’) are businesses marketing genetic testing to consumers over the Internet. While much has been written about these new businesses, little attention has been given to their roles in science communication. This paper provides an analysis of the gene concept presented to customers and the relation between the information given and the science behind PG. Two quite different gene concepts are present in company rhetoric, but only one features in the science. (...)
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  27.  72
    Improving the Justice‐Based Argument for Conducting Human Gene Editing Research to Cure Sickle Cell Disease.Berman Chan - 2020 - Bioethics 34 (2):200-202.
    In a recent article, Marilyn Baffoe-Bonnie offers three arguments for conducting CRISPR/Cas9 biotechnology research to cure sickle-cell disease (SCD) based on addressing historical and current injustices in SCD research and care. I show that her second and third arguments suffer from roughly the same defect, which is that they really argue for something else rather than for conducting CRISPR/Cas9 research in particular for SCD. For instance, the second argument argues that conducting this gene therapy research would improve the relationship (...)
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  28. Cohesion, Gene Flow, and the Nature of Species.Matthew J. Barker & Robert A. Wilson - 2010 - Journal of Philosophy 107 (2):59-77.
    A far-reaching and influential view in evolutionary biology claims that species are cohesive units held together by gene flow. Biologists have recognized empirical problems facing this view; after sharpening the expression of the view, we present novel conceptual problems for it. At the heart of these problems is a distinction between two importantly different concepts of cohesion, what we call integrative and response cohesion. Acknowledging the distinction problematizes both the explanandum of species cohesion and the explanans of gene (...)
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  29.  50
    The Ontology of the Gene Ontology.Barry Smith, Jennifer Williams & Steffen Schulze-Kremer - 2003 - In AMIA 2003 Symposium Proceedings. Washington, DC: AMIA. pp. 609-613.
    The rapidly increasing wealth of genomic data has driven the development of tools to assist in the task of representing and processing information about genes, their products and their functions. One of the most important of these tools is the Gene Ontology (GO), which is being developed in tandem with work on a variety of bioinformatics databases. An examination of the structure of GO, however, reveals a number of problems, which we believe can be resolved by taking account of (...)
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  30.  27
    Asexual Organisms, Identity and Vertical Gene Transfer.Gunnar Babcock - 2020 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 81:101265.
    This paper poses a problem for traditional phylogenetics: The identity of organisms that reproduce through fission can be understood in several different ways. This prompts questions about how to differentiate parent organisms from their offspring, making vertical gene transfer unclear. Differentiating between parents and offspring stems from what I call the identity problem. How the problem is resolved has implications for phylogenetic groupings. If the identity of a particular asexual organism persists through fission, the vertical lineage on a phylogenetic (...)
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  31.  32
    History in the Gene: Negotiations Between Molecular and Organismal Anthropology.Marianne Sommer - 2008 - Journal of the History of Biology 41 (3):473-528.
    In the advertising discourse of human genetic database projects, of genetic ancestry tracing companies, and in popular books on anthropological genetics, what I refer to as the anthropological gene and genome appear as documents of human history, by far surpassing the written record and oral history in scope and accuracy as archives of our past. How did macromolecules become "documents of human evolutionary history"? Historically, molecular anthropology, a term introduced by Emile Zuckerkandl in 1962 to characterize the study of (...)
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  32. Controlled Vocabularies in Bioinformatics: A Case Study in the Gene Ontology.Barry Smith & Anand Kumar - 2004 - Drug Discovery Today: Biosilico 2 (6):246-252.
    The automatic integration of information resources in the life sciences is one of the most challenging goals facing biomedical informatics today. Controlled vocabularies have played an important role in realizing this goal, by making it possible to draw together information from heterogeneous sources secure in the knowledge that the same terms will also represent the same entities on all occasions of use. One of the most impressive achievements in this regard is the Gene Ontology (GO), which is rapidly acquiring (...)
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  33. Gene Mobility and the Concept of Relatedness.Jonathan Birch - 2014 - Biology and Philosophy 29 (4):445-476.
    Cooperation is rife in the microbial world, yet our best current theories of the evolution of cooperation were developed with multicellular animals in mind. Hamilton’s theory of inclusive fitness is an important case in point: applying the theory in a microbial setting is far from straightforward, as social evolution in microbes has a number of distinctive features that the theory was never intended to capture. In this article, I focus on the conceptual challenges posed by the project of extending Hamilton’s (...)
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  34.  32
    Demystifying Eukaryote Lateral Gene Transfer.Michelle M. Leger, Laura Eme, Courtney W. Stairs & Andrew J. Roger - 2018 - Bioessays 40 (5):1700242.
    In a recent BioEssays paper [W. F. Martin, BioEssays 2017, 39, 1700115], William Martin sharply criticizes evolutionary interpretations that involve lateral gene transfer into eukaryotic genomes. Most published examples of LGTs in eukaryotes, he suggests, are in fact contaminants, ancestral genes that have been lost from other extant lineages, or the result of artefactual phylogenetic inferences. Martin argues that, except for transfers that occurred from endosymbiotic organelles, eukaryote LGT is insignificant. Here, in reviewing this field, we seek to correct (...)
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  35. Difference in Kind: Observations on the Distinction of the Megista Gene.David Ambuel - 2013 - In Beatriz Bossi & Thomas M. Robinson (eds.), Plato's Sophist Revisited. de Gruyter. pp. 247-268.
    It is argued that the analysis by which the gene are differentiated in the dialogue is an exercise in studied ambiguities informed by an Eleatic logic of strict dichotomy that was the underpinning of the Sophist's method of division. By this dialectical drill, Plato shows that the metaphysics underlying the Visitor's method fails to adequately distinguish what it means to have a character from what it means to be a character, and therefore remains inadequate to track down the sophist (...)
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  36. Naturalism, Evidence and Creationism: The Case of Phillip Johnson[REVIEW]Robert T. Pennock - 1996 - Biology and Philosophy 11 (4):543-559.
    Phillip Johnson claims that Creationism is a better explanation of the existence and characteristics of biological species than is evolutionary theory. He argues that the only reason biologists do not recognize that Creationist's negative arguments against Darwinism have proven this is that they are wedded to a biased ideological philosophy —Naturalism — which dogmatically denies the possibility of an intervening creative god. However,Johnson fails to distinguish Ontological Naturalism from Methodological Naturalism. Science makes use of the latter and I (...)
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  37. Driven to Extinction? The Ethics of Eradicating Mosquitoes with Gene-Drive Technologies.Jonathan Pugh - 2016 - Journal of Medical Ethics 42 (9):578-581.
    Mosquito-borne diseases represent a significant global disease burden, and recent outbreaks of such diseases have led to calls to reduce mosquito populations. Furthermore, advances in ‘gene-drive’ technology have raised the prospect of eradicating certain species of mosquito via genetic modification. This technology has attracted a great deal of media attention, and the idea of using gene-drive technology to eradicate mosquitoes has been met with criticism in the public domain. In this paper, I shall dispel two moral objections that (...)
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  38. A Note on Johnson’s ‘A Refutation of Skeptical Theism’.Timothy Perrine - 2015 - Sophia 54 (1):35-43.
    In a recent article, David Kyle Johnson has claimed to have provided a ‘refutation’ of skeptical theism. Johnson’s refutation raises several interesting issues. But in this note, I focus on only one—an implicit principle Johnson uses in his refutation to update probabilities after receiving new evidence. I argue that this principle is false. Consequently, Johnson’s refutation, as it currently stands, is undermined.
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  39.  34
    The Gene’s-Eye View, Major Transitions and the Formal Darwinism Project.Andrew F. G. Bourke - 2014 - Biology and Philosophy 29 (2):241-248.
    I argue that Grafen’s formal darwinism project could profitably incorporate a gene’s-eye view, as informed by the major transitions framework. In this, instead of the individual being assumed to maximise its inclusive fitness, genes are assumed to maximise their inclusive fitness. Maximisation of fitness at the individual level is not a straightforward concept because the major transitions framework shows that there are several kinds of biological individual. In addition, individuals have a definable fitness, exhibit individual-level adaptations and arise in (...)
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  40. Networks of Gene Regulation, Neural Development and the Evolution of General Capabilities, Such as Human Empathy.Alfred Gierer - 1998 - Zeitschrift Für Naturforschung C - A Journal of Bioscience 53:716-722.
    A network of gene regulation organized in a hierarchical and combinatorial manner is crucially involved in the development of the neural network, and has to be considered one of the main substrates of genetic change in its evolution. Though qualitative features may emerge by way of the accumulation of rather unspecific quantitative changes, it is reasonable to assume that at least in some cases specific combinations of regulatory parts of the genome initiated new directions of evolution, leading to novel (...)
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  41.  14
    Gene Ontology Annotations: What They Mean and Where They Come From.P. Hill David, Barry Smith, S. McAndrews-Hill Monica & A. Blake Judith - 2008 - BMC Bioinformatics 9 (Suppl 5):S2.
    The computational genomics community has come increasingly to rely on the methodology of creating annotations of scientific literature using terms from controlled structured vocabularies such as the Gene Ontology (GO). We here address the question of what such annotations signify and of how they are created by working biologists. Our goal is to promote a better understanding of how the results of experiments are captured in annotations in the hope that this will lead to better representations of biological reality (...)
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  42. Disability, Gene Therapy and Eugenics - a Challenge to John Harris.S. M. Reindal - 2000 - Journal of Medical Ethics 26 (2):89 - 94.
    This article challenges the view of disability presented by Harris in his article, “Is gene therapy a form of eugenics?”1 It is argued that his definition of disability rests on an individual model of disability, where disability is regarded as a product of biological determinism or “personal tragedy” in the individual. Within disability theory this view is often called “the medical model” and it has been criticised for not being able to deal with the term “disability”, but only with (...)
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  43.  34
    Genome Evolution is Driven by Gene Expression-Generated Biophysical Constraints Through RNA-Directed Genetic Variation: A Hypothesis.Didier Auboeuf - 2017 - Bioessays 39 (10):1700069.
    The biogenesis of RNAs and proteins is a threat to the cell. Indeed, the act of transcription and nascent RNAs challenge DNA stability. Both RNAs and nascent proteins can also initiate the formation of toxic aggregates because of their physicochemical properties. In reviewing the literature, I show that co-transcriptional and co-translational biophysical constraints can trigger DNA instability that in turn increases the likelihood that sequences that alleviate the constraints emerge over evolutionary time. These directed genetic variations rely on the biogenesis (...)
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  44.  31
    A Concept Divided: Ralph Johnson's Definition of Argument. [REVIEW]Christopher W. Tindale - 2002 - Argumentation 16 (3):299-309.
    Ralph Johnson's Manifest Rationality (2000) is a major contribution to the field of informal logic, but the concept of argument that is central to its project suffers from a tension between the components that comprise it. This paper explores and addresses that tension by examining the implications of each of five aspects of the definition of ‘argument’.
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  45.  22
    The Ethical Landscape of Gene Drive Research.Daniel Edward Callies - 2019 - Bioethics 33 (9):1091-1097.
    Gene drive technology has immense potential. The ability to bypass the laws of Mendelian inheritance and almost ensure the transmission of specific genetic material to future generations creates boundless possibilities. But alongside these boundless possibilities are major social and ethical issues. This article aims to introduce gene drive technology, some of its potential applications, and some of the social and ethical issues that arise during research into the technology. For example, is investigation into gene drives hubristic? Would (...)
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  46.  24
    Ecological Models for Gene Therapy. II. Niche Construction, Nongenetic Inheritance, and Ecosystem Perturbations.Arnaud Pocheville, Maël Montévil & Régis Ferrière - 2014 - Biological Theory 9 (4):414-422.
    In this paper, we apply the perspective of intra-organismal ecology by investigating a family of ecological models suitable to describe a gene therapy to a particular metabolic disorder, the adenosine deaminase deficiency (ADA-SCID). The gene therapy is modeled as the prospective ecological invasion of an organ (here, bone marrow) by genetically modified stem cells, which then operate niche construction in the cellular environment by releasing an enzyme they synthesize. We show that depending on the chosen order (a choice (...)
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  47.  21
    Johnson, MacIntyre, and the Practice of Argumentation.Tone Kvernbekk - 2008 - Informal Logic 28 (3):262-278.
    This article is a discussion of Ralph Johnson’s concept of practice of argumentation. Such practice is characterized by three properties: (1) It is teleological, (2) it is dialectical, and (3) it is manifestly rational. I argue that Johnson’s preferred definition of practice—which is Alasdair MacIntyre’s concept of practice as a human activity with internal goods accessible through partcipation in that same activity—does not fit these properties or features. I also suggest that this failure should not require Johnson (...)
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  48.  53
    Dependence Relationships Between Gene Ontology Terms Based on TIGR Gene Product Annotations.Anand Kumar, Barry Smith & Christian Borgelt - 2004 - Proceedings of the 3rd International Workshop on Computational Terminology 2004:31-38.
    The Gene Ontology is an important tool for the representation and processing of information about gene products and functions. It provides controlled vocabularies for the designations of cellular components, molecular functions, and biological processes used in the annotation of genes and gene products. These constitute three separate ontologies, of cellular components), molecular functions and biological processes, respectively. The question we address here is: how are the terms in these three separate ontologies related to each other? We use (...)
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  49. The 'Warrior Gene' and the Mãori People: The Responsibility of the Geneticists.Laurence Perbal - 2013 - Bioethics 27 (7):382-387.
    The ‘gene of’ is a teleosemantic expression that conveys a simplistic and linear relationship between a gene and a phenotype. Throughout the 20th century, geneticists studied these genes of traits. The studies were often polemical when they concerned human traits: the ‘crime gene’, ‘poverty gene’, ‘IQ gene’, ‘gay gene’ or ‘gene of alcoholism’. Quite recently, a controversy occurred in 2006 in New Zealand that started with the claim that a ‘warrior gene’ exists (...)
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  50.  2
    Teilhard de Chardin’s Oeuvre Within an Ongoing Discussion of a Gene Drive Release for Public Health Reasons.Anto Čartolovni - 2017 - Life Sciences, Society and Policy 13 (1):1-15.
    Within the domain of public health, vector-borne diseases are among the most vehemently discussed issues. Recent scientific breakthroughs in genome editing technology provided a solution to this issue in the form of a gene drive that might decrease and even eradicate vector-borne diseases. Gene drives are engineered, and designed genes that can break typical inheritance rules and be passed to almost all of the carrier’s offspring. This genome editing and gene drive technology has become a powerful tool (...)
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