80 found
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  1.  2
    Demented patients and the quandaries of identity: setting the problem, advancing a proposal.Giovanni Boniolo - 2021 - History and Philosophy of the Life Sciences 43 (1):1-16.
    In the paper, after clarifying terms such as ‘identity’, ‘self’ and ‘personhood’, I propose an empirical account of identity based on the notion of “whole phenotype”. This move allows one to claim the persistence of the individuals before and after their being affected by dementia. Furthermore, I show how this account permits us to address significant questions related to demented individuals’ loss of the capacity of moral decisions.
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  2.  24
    Molecular Pathways and the Contextual Explanation of Molecular Functions.Giovanni Boniolo & Raffaella Campaner - 2018 - Biology and Philosophy 33 (3-4):24.
    Much of the recent philosophical debate on causation and causal explanation in the biological and biomedical sciences has focused on the notion of mechanism. Mechanisms, their nature and epistemic roles have been tackled by a range of so-called neo-mechanistic theories, and widely discussed. Without denying the merits of this approach, our paper aims to show how lately it has failed to give proper credit to processes, which are central to the field, especially of contemporary molecular biology. Processes can be summed (...)
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  3.  38
    Life Sciences for Philosophers and Philosophy for Life Scientists: What Should We Teach?Giovanni Boniolo & Raffaella Campaner - 2020 - Biological Theory 15 (1):1-11.
    Following recent debate on the relations between philosophy of science and the sciences, we wish to draw attention to some actual ways of training both young philosophers of science and young life scientists and clinicians. First, we recall a successful case of training philosophers of the life sciences in a strictly scientific environment. Second, after a brief review of the reasons why life scientists and clinicians are currently asking for more ethics, more methodology of science, and more philosophy of science (...)
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  4.  80
    The Identity of Living Beings, Epigenetics, and the Modesty of Philosophy.Giovanni Boniolo & Giuseppe Testa - 2012 - Erkenntnis 76 (2):279-298.
    Two problems related to the biological identity of living beings are faced: the who-problem (which are the biological properties making that living being unique and different from the others?); the persistence-problem (what does it take for a living being to persist from a time to another?). They are discussed inside a molecular biology framework, which shows how epigenetics can be a good ground to provide plausible answers. That is, we propose an empirical solution to the who-problem and to the persistence-problem (...)
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  5.  88
    Kant’s Explication and Carnap’s Explication: The Redde Rationem.Giovanni Boniolo - 2003 - International Philosophical Quarterly 43 (3):289-298.
    In this paper I will compare the concept of explication à la Carnap and the concept of explication à la Kant. This essay should primarily be seen as a comparison of two different philosophical styles, but it is also intended as a vindication of what Kant wrote and what Carnap forgot to read.
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  6.  28
    Reliability of Molecular Imaging Diagnostics.Elisabetta Lalumera, Stefano Fanti & Giovanni Boniolo - forthcoming - Synthese:1-17.
    Advanced medical imaging, such as CT, fMRI and PET, has undergone enormous progress in recent years, both in accuracy and utilization. Such techniques often bring with them an illusion of immediacy, the idea that the body and its diseases can be directly inspected. In this paper we target this illusion and address the issue of the reliability of advanced imaging tests as knowledge procedures, taking positron emission tomography in oncology as paradigmatic case study. After individuating a suitable notion of reliability, (...)
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  7.  37
    Adding Logic to the Toolbox of Molecular Biology.Giovanni Boniolo, Marcello D’Agostino, Mario Piazza & Gabriele Pulcini - 2015 - European Journal for Philosophy of Science 5 (3):399-417.
    The aim of this paper is to argue that logic can play an important role in the “toolbox” of molecular biology. We show how biochemical pathways, i.e., transitions from a molecular aggregate to another molecular aggregate, can be viewed as deductive processes. In particular, our logical approach to molecular biology — developed in the form of a natural deduction system — is centered on the notion of Curry-Howard isomorphism, a cornerstone in nineteenth-century proof-theory.
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  8.  65
    Kant’s Explication and Carnap’s Explication.Giovanni Boniolo - 2003 - International Philosophical Quarterly 43 (3):289-298.
    In this paper I will compare the concept of explication à la Carnap and the concept of explication à la Kant. This essay should primarily be seen as a comparison of two different philosophical styles, but it is also intended as a vindication of what Kant wrote and what Carnap forgot to read.
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  9.  21
    Rethinking Medical Humanities.Luca Chiapperino & Giovanni Boniolo - 2014 - Journal of Medical Humanities 35 (4):377-387.
    This paper questions different conceptions of Medical Humanities in order to provide a clearer understanding of what they are and why they matter. Building upon former attempts, we defend a conception of Medical Humanities as a humanistic problem-based approach to medicine aiming at influencing its nature and practice. In particular, we discuss three main conceptual issues regarding the overall nature of this discipline: a problem-driven approach to Medical Humanities; the need for an integration of Medical Humanities into medicine; the methodological (...)
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  10.  13
    A Trust‐Based Pact in Research Biobanks. From Theory to Practice.Virginia Sanchini, Giuseppina Bonizzi, Davide Disalvatore, Massimo Monturano, Salvatore Pece, Giuseppe Viale, Pier Paolo Di Fiore & Giovanni Boniolo - 2016 - Bioethics 30 (4):260-271.
    Traditional Informed Consent is becoming increasingly inadequate, especially in the context of research biobanks. How much information is needed by patients for their consent to be truly informed? How does the quality of the information they receive match up to the quality of the information they ought to receive? How can information be conveyed fairly about future, non-predictable lines of research? To circumvent these difficulties, some scholars have proposed that current consent guidelines should be reassessed, with trust being used as (...)
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  11.  99
    Vagueness, Kant and Topology: A Study of Formal Epistemology.Giovanni Boniolo & Silvio Valentini - 2008 - Journal of Philosophical Logic 37 (2):141-168.
    In this paper we propose an approach to vagueness characterised by two features. The first one is philosophical: we move along a Kantian path emphasizing the knowing subject’s conceptual apparatus. The second one is formal: to face vagueness, and our philosophical view on it, we propose to use topology and formal topology. We show that the Kantian and the topological features joined together allow us an atypical, but promising, way of considering vagueness.
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  12.  5
    A Logic of Non-Monotonic Interactions.Giovanni Boniolo, Marcello DʼAgostino, Mario Piazza & Gabriele Pulcini - 2013 - Journal of Applied Logic 11 (1):52-62.
  13.  39
    Evolutionary Ethics and Contemporary Biology.Giovanni Boniolo & Gabriele De Anna (eds.) - 2006 - Cambridge University Press.
    How can the discoveries made in the biological sciences play a role in a discussion on the foundation of ethics? This book responds to this question by examining how evolutionism can explain and justify the existence of ethical normativity and the emergence of particular moral systems. Written by a team of philosophers and scientists, the essays collected in this volume deal with the limits of evolutionary explanations, the justifications of ethics, and methodological issues concerning evolutionary accounts of ethics, among other (...)
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  14.  59
    Biology Without Information.Giovanni Boniolo - 2003 - History and Philosophy of the Life Sciences 25 (2):255-273.
    Over these last few years once again the relationship between biology and information has been debated with great liveliness. The crucial points concern the meaning of the term ‘information’ and whether the so-called “information talk” is really necessary inside biology.I will proceed by first commenting on some points of the debate (§ 2), then showing that a biophysical account of the process from the nucleotide sequences to the correlated amino acid sequences is possible (§ 3). In this way, I will (...)
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  15.  43
    On Biological Identity.Giovanni Boniolo & Massimiliano Carrara - 2004 - Biology and Philosophy 19 (3):443-457.
    In our paper, we propose a relativisticand metaphysically neutral identity criterionfor biological entities. We start from thecriterion of genidentity proposed by K. Lewinand H. Reichenbach. Then we enrich it to renderit more philosophical powerful and so capableof dealing with the real transformations thatoccur in the extremely variegated biologicalworld.
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  16.  17
    Death and Transplantation: Let's Try to Get Things Methodologically Straight.Giovanni Boniolo - 2007 - Bioethics 21 (1):32–40.
  17.  51
    Trusted Consent and Research Biobanks: Towards a 'New Alliance' Between Researchers and Donors.Giovanni Boniolo, Pier Paolo di Fiore & Salvatore Pece - 2012 - Bioethics 26 (2):93-100.
    We argue that, in the case of research biobanks, there is a need to replace the currently used informed consent with trusted consent. Accordingly, we introduce a proposal for the structure of the latter. Further, we discuss some of the issues that can be addressed effectively through our proposal. In particular, we illustrate: i) which research should be authorized by donors; ii) how to regulate access to information; iii) the fundamental role played by a Third Party Authority in assuring compliance (...)
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  18. On Scientific Representations: From Kant to a New Philosophy of Science.Giovanni Boniolo - 2007 - Palgrave-Macmillan.
    Scientific concepts, laws, theories, models and thought experiments are representations but uniquely different. In On Scientific Representation each is given a full philosophical exploration within an original, coherent philosophical framework that is strongly rooted in the Kantian tradition (Kant, Hertz, Vaihinger, Cassirer). Through a revisionist historical approach, Boniolo shows how the Kantian tradition can help us renew and rethink contemporary issues in epistemology and the philosophy of science.
     
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  19. The Descent of Instinct and the Ascent of Ethics.Giovanni Boniolo - 2006 - In Giovanni Boniolo & Gabriele De Anna (eds.), Evolutionary Ethics and Contemporary Biology. Cambridge University Press. pp. 27--40.
     
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  20.  67
    The Four Faces of Omission: Ontology, Terminology, Epistemology, and Ethics.Giovanni Boniolo & Gabriele De Anna - 2006 - Philosophical Explorations 9 (3):277 – 293.
    In this paper, the ontological, terminological, epistemological, and ethical aspects of omission are considered in a coherent and balanced framework, based on the idea that there are omissions which are actions and omissions which are non-actions. In particular, we suggest that the approach to causation which best deals with omission is Mackie's INUS conditional proposal. We argue that omissions are determined partly by the ontological conditional structure of reality, and partly by the interests, beliefs, and values of observers. The final (...)
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  21.  47
    Clustering Humans: On Biological Boundaries.Ludovica Lorusso & Giovanni Boniolo - 2008 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 39 (1):163-170.
    We inquire into the notions of ‘boundary’ and ‘cluster’ in the fields of medical genetics, pharmacogenetics, and population genetics. First we show that the two notions are not well discussed in literature. Then we propose a promising explication of them, in which we argue that clustering is always ‘property laden’, that is, fundamentally dependent on decisions about the properties to be taken into account. In particular we suggest three different kinds of properties that have a role in these decisions. That (...)
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  22.  44
    On Spatial and Temporal Ex Mensura Boundaries.Giovanni Boniolo, Rossella Faraldo & Antonio Saggion - 2009 - Foundations of Science 14 (3):181-193.
    In this paper we will propose an empirical analysis of spatial and temporal boundaries. Unlike other proposals, which deal mainly with the commonsense level of the subject, we will ground our explication on well-established scientific practice and language. In this way we show how to reconsider in an innovative way questions such as the distinction between the bona fide boundaries and the fiat boundaries, the thickness and the ownership of the boundaries. At the same time we propose a division between (...)
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  23.  91
    On a Unified Theory of Models and Thought Experiments in Natural Sciences.Giovanni Boniolo - 1997 - International Studies in the Philosophy of Science 11 (2):121 – 142.
    In this paper a unified theory of models and thought experiments is proposed by considering them as fictions, la Vaihinger. In order to reach this aim, the Hertzian and Botzmannian interpretation of theories as Bilder is reconsidered.
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  24.  18
    Potential Pitfalls in the Evaluation of Ethics Consultation: The Case of Ethical Counseling.Alma Linkeviciute, Kris Dierickx, Virginia Sanchini & Giovanni Boniolo - 2016 - American Journal of Bioethics 16 (3):56-57.
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  25. Theory and Experiment. The Case of Eötvös' Experiments.Giovanni Boniolo - 1992 - British Journal for the Philosophy of Science 43 (4):459-486.
    By analysing the historical case of the proportionality between inertia and gravitation, it is possible to reconstruct one of the most relevant moments in the history of physics, that is to say, the one linked with Eötvös' experiments. At the same time, this reconstruction offers the opportunity to carry out philosophical considerations about the relationship between theory and experiment and about the concept of incommensurability.
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  26.  41
    Is an Account of Identity Necessary for Bioethics? What Post-Genomic Biomedicine Can Teach Us.Giovanni Boniolo - 2013 - Studies in History and Philosophy of Biological and Biomedical Sciences 44 (3):401-411.
    Is a theory of identity necessary for bioethics? In this paper I investigate that question starting from an empirical explication of identity based on post-genomics, in particular on epigenetics. After analysing whether the classic problems a theory of identity has to cope with also affect the proposed epigenetic account of identity, I deal with three topics to offer an insight on the relationship between that account and bioethics.
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  27.  36
    Libertarian Paternalism and Health Care Policy: A Deliberative Proposal. [REVIEW]Giuseppe Schiavone, Gabriele De Anna, Matteo Mameli, Vincenzo Rebba & Giovanni Boniolo - 2014 - Medicine, Health Care and Philosophy 17 (1):103-113.
    Cass Sunstein and Richard Thaler have been arguing for what they named libertarian paternalism (henceforth LP). Their proposal generated extensive debate as to how and whether LP might lead down a full-blown paternalistic slippery slope. LP has the indubitable merit of having hardwired the best of the empirical psychological and sociological evidence into public and private policy making. It is unclear, though, to what extent the implementation of policies so constructed could enhance the capability for the exercise of an autonomous (...)
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  28.  27
    On Molecular Mechanisms and Contexts of Physical Explanation.Giovanni Boniolo - 2013 - Biological Theory 7 (3):256-265.
    In this article, two issues regarding mechanisms are discussed. The first concerns the relationships between “mechanism description” and “mechanism explanation.” It is proposed that it is rather plausible to think of them as two distinct epistemic acts. The second deals with the different molecular biology explanatory contexts, and it is shown that some of them require physics and its laws.
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  29.  10
    Concepts as representations and as rules.Giovanni Boniolo - 2001 - Revista de Filosofía (Madrid) 25 (1):93-115.
    In this paper a post-Kantian theory of scientific concepts is proposed. In particular, by differentiating the representational level, the intentional level and the real level, it is argued that a scientific concept has to be understood both as a representation and as a rule.
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  30.  25
    A Contextualized Approach to Biological Explanation.Giovanni Boniolo - 2005 - Philosophy 80 (2):219-247.
    In the paper, starting from a slightly modified version of van Fraassen's pragmatic approach to explanation, I will propose a pragmatical meta-model for the different biological explanatory models. That is, I will offer a pragmatic point of view to rule different explanatory models in function of the biological context from which the given biologist explains.
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  31.  3
    Is an Account of Identity Necessary for Bioethics?: What Post-Genomic Biomedicine Can Teach Us.Giovanni Boniolo - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (3):401-411.
    Is a theory of identity necessary for bioethics? In this paper I investigate that question starting from an empirical explication of identity based on post-genomics, in particular on epigenetics. After analysing whether the classic problems a theory of identity has to cope with also affect the proposed epigenetic account of identity, I deal with three topics to offer an insight on the relationship between that account and bioethics.
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  32.  40
    The Ontogenesis of Human Identity.Giovanni Boniolo - 2005 - Royal Institute of Philosophy Supplement 56:5-6.
    “ >. Das hiess doch: Wenn du dir gewisse Tatsachen anders denkst,sie anders beschreibst, als sie sind, dann kannst du die Anwendung gewisser Begriffe dir nicht mehr vorstellen, weil die Regeln ihrer Anwendung kein Analogon unter den neuen Umständen haben.”.
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  33.  14
    A Defining Analysis of the Life and Death Dyad: Paving the Way for an Ethical Debate.Giovanni Boniolo & Pier Paolo Di Fiore - 2008 - Journal of Medicine and Philosophy 33 (6):609-634.
    We discuss the meaning of “being alive” and “being dead.” Our primary aim is to pave the way for a sound and accurate ethical debate concerning these two concepts. In particular, we analyze a metabolic approach and a genetic one and discuss the reasons for their failure to constitute a good starting point for successive debates. We argue that any ethical or social discussion of topics involving life and death must introduce cultural constructs such as, on the one hand, the (...)
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  34.  6
    Clustering Humans: On Biological Boundaries.Ludovica Lorusso & Giovanni Boniolo - 2008 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 39 (1):163-170.
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  35.  33
    Notes on the Philosophical Status of Nuclear Physics.Giovanni Boniolo, Carlo Petrovich & Gualtiero Pisent - 2002 - Foundations of Science 7 (4):425-452.
    In our paper we propose a philosophicalanalysis, based on the notion ofphenomenological model, of Nuclear Physics. Inthis way, we will show some peculiarities ofthis branch of physics.
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  36.  9
    Causality and Methodology. Notes on Thanatochronological Estimations.Giovanni Boniolo, Mirella Libero & Anna Aprile - 2005 - History and Philosophy of the Life Sciences 27 (3/4):381 - 393.
    The authors propose some methodological considerations on thanatochronological estimations. They first consider the problem of the definition of death, and then they deal with the issue of the estimations of death time, that is, with the Post-Mortem Interval (PMI). As regards the first question, they note that it does not concern only the definition of death, but also the choice of a particular kind of definition of 'definition'. With reference to the second question, the authors suggest a causal model showing (...)
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  37.  15
    Wormholes and Timelike Curves: Is There Room for the Grandfather Paradox?Giovanni Boniolo - 1999 - In Maria Luisa Dalla Chiara (ed.), Language, Quantum, Music. pp. 143--157.
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  38.  11
    Introduction: Foundations of Clinical Reasoning—An Epistemological Stance.Mattia Andreoletti, Paola Berchialla, Giovanni Boniolo & Daniele Chiffi - 2019 - Topoi 38 (2):389-394.
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  39.  23
    Elvio Baccarini.Josip Balabanić, Damir Barbarić, Boran Berčić, Giovanni Boniolo, Branka Brujić, Alex Byrne, Erik Carlson, Maudemarie Clark, Nadežda Čačinovič & Zvonimir Čuljak - 2008 - Prolegomena 7:1.
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  40. Browse Papers.Giovanni Boniolo - manuscript
    Recent discussion of mechanism has suggested new approaches to several issues in the philosophy of science, including theory structure, causal explanation, and reductionism. Here, I apply what I take to be the fruits of the 'new mechanical philosophy' to an analysis of a contemporary debate in evolutionary biology about the role of natural selection in speciation. Traditional accounts of that debate focus on the geographic context of genetic divergence--namely, whether divergence in the absence of geographic isolation is possible (or significant). (...)
     
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  41.  8
    Complexity and integration. A philosophical analysis of how cancer complexity can be faced in the era of precision medicine.Giovanni Boniolo & Raffaella Campaner - 2019 - European Journal for Philosophy of Science 9 (3):1-25.
    Complexity and integration are longstanding widely debated issues in philosophy of science and recent contributions have largely focused on biology and biomedicine. This paper specifically considers some methodological novelties in cancer research, motivated by various features of tumours as complex diseases, and shows how they encourage some rethinking of philosophical discourses on those topics. In particular, we discuss the integrative-cluster approach, and analyse its potential in the epistemology of cancer. We suggest that, far from being the solution to tame cancer (...)
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  42. Complexity and integration. A philosophical analysis of how cancer complexity can be faced in the era of precision medicine.Giovanni Boniolo & Raffaella Campaner - 2019 - European Journal for Philosophy of Science 9 (3):1-25.
    Complexity and integration are longstanding widely debated issues in philosophy of science and recent contributions have largely focused on biology and biomedicine. This paper specifically considers some methodological novelties in cancer research, motivated by various features of tumours as complex diseases, and shows how they encourage some rethinking of philosophical discourses on those topics. In particular, we discuss the integrative-cluster approach, and analyse its potential in the epistemology of cancer. We suggest that, far from being the solution to tame cancer (...)
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  43. Complexity and integration. A philosophical analysis of how cancer complexity can be faced in the era of precision medicine.Giovanni Boniolo & Raffaella Campaner - 2019 - European Journal for Philosophy of Science 9 (3):1-25.
    Complexity and integration are longstanding widely debated issues in philosophy of science and recent contributions have largely focused on biology and biomedicine. This paper specifically considers some methodological novelties in cancer research, motivated by various features of tumours as complex diseases, and shows how they encourage some rethinking of philosophical discourses on those topics. In particular, we discuss the integrative-cluster approach, and analyse its potential in the epistemology of cancer. We suggest that, far from being the solution to tame cancer (...)
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  44.  21
    Causal Reasoning and Clinical Practice: Challenges From Molecular Biology.Giovanni Boniolo & Raffaella Campaner - 2019 - Topoi 38 (2):423-435.
    Not only has the philosophical debate on causation been gaining ground in the last few decades, but it has also increasingly addressed the sciences. The biomedical sciences are among the most prominent fields that have been considered, with a number of works tackling the understanding of the notion of cause, the assessment of genuinely causal relations and the use of causal knowledge in applied contexts. Far from denying the merits of the debate on causation and the major theories it comprises, (...)
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  45.  7
    Decomposing Biological Complexity Into a Conjunction of Theorems. The Case of the Melanoma Network.Giovanni Boniolo & Luisa Lanfrancone - 2016 - Humana Mente 9 (30).
    The complexity of intracellular molecular pathways can be simplified by the use of Network Biology that breaks down the intricacy of biological processes into components and interactions among them. In the paper we show that any complex interactome, that is, a biological network representing protein-protein, protein-DNA and DNA-RNA interactions, can be decomposed into a conjunction of logical theorems expressed in terms of Zsyntax, a formal language which allows representing biological pathways. This result, illustrated with the case study of melanoma network, (...)
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  46. Esiste il metodo della fisica?Giovanni Boniolo - 1995 - Nuova Civiltà Delle Macchine 13 (1/2):42-48.
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  47. Filosofia Della Fisica.Giovanni Boniolo & Silvio Bergia - 1997
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  48. Gli errori scientifici di Popper.Giovanni Boniolo - 2000 - Nuova Civiltà Delle Macchine 18 (2).
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  49. Genetic Influences on Moral Capacity. What Genetic Mutants Can Teach Us.Giovanni Boniolo & Paolo Vezzoni - 2006 - In Giovanni Boniolo & Gabriele De Anna (eds.), Evolutionary Ethics and Contemporary Biology. Cambridge University Press. pp. 77--96.
     
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  50. The Role of Mathematics in Physical Sciences: Interdisciplinary and Philosophical Aspects.Giovanni Boniolo, Paolo Budinich & Majda Trobok (eds.) - 2005 - Springer.
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