Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

The phenomenon of the New Genetics raises complex social problems, particularly those of privacy. This book offers ethical and legal perspectives on the questions of a right to know and not to know genetic information from the standpoint of individuals, their relatives, employers, insurers and the state. Graeme Laurie provides a unique definition of privacy, including a concept of property rights in the person, and argues for stronger legal protection of privacy in the shadow of developments in human genetics. (...) He challenges the role and the limits of established principles in medical law and ethics, including respect for patient autonomy and confidentiality. This book will interest lawyers, philosophers and doctors concerned both with genetic information and issues of privacy; it will also interest genetic counsellors, researchers, and policy makers worldwide for its practical stance on dilemmas in modern genetic medicine. (shrink)

[Graeme Forbes] In I, I summarize the semantics for the relational/notional distinction for intensional transitives developed in Forbes (2000b). In II-V I pursue issues about logical consequence which were either unsatisfactorily dealt with in that paper or, more often, not raised at all. I argue that weakening inferences, such as 'Perseus seeks a mortal gorgon, therefore Perseus seeks a gorgon', are valid, but that disjunction inferences, such as 'Perseus seeks a mortal gorgon, therefore Perseus seeks a mortal gorgon or (...) an immortal gorgon', are invalid. Since 'a gorgon' and 'a mortal gorgon or an immortal gorgon' are extensionally and intensionally the same quantifier, it is not completely trivial to arrange the semantics of intensional transitives so that this classification of the inferences is obtained. (This paper is an abridged version of Forbes (2001a); the latter will be incorporated into a forthcoming monograph, Attitude Problems.) /// [Jennifer Saul] This paper discusses the question of which verbs are intensional transitives. In particular, I ask which verbs Forbes should take to be intensional transitives. I argue that it is very difficult to arrive at a clear and plausible understanding of what an intensional transitive is-making it difficult to answer these questions. I end by briefly raising some questions about the usefulness of the category of intensional transitives. (shrink)

From Detroit Red to El-Hajj Malik El-Shabazz, the man best known as Malcolm X restlessly redefined himself throughout a controversial life. His transformations have appeared repeatedly in books, photographs, paintings, and films, while his murder set in motion a series of tugs-of-war among journalists, biographers, artists, and his ideological champions over the interpretation of his cultural meaning. This book marks the first systematic examination of the images generated by this iconic cultural figure--images readily found on everything from T-shirts and hip-hop (...) album covers to coffee mugs. Graeme Abernethy captures both the multiplicity and global import of a person who has been framed as both villain and hero, cast by mainstream media during his lifetime as "the most feared man in American history," and elevated at his death as a heroic emblem of African American identity. As Abernethy shows, the resulting iconography of Malcolm X has shifted as profoundly as the American racial landscape itself. Abernethy explores Malcolm's visual prominence in the eras of civil rights, Black Power, and hip-hop. He analyzes this enigmatic figure's representation across a variety of media from 1960s magazines to urban murals, tracking the evolution of Malcolm's iconography from his autobiography and its radical milieu through the appearance of Spike Lee's 1992 biopic and beyond. Its remarkable gallery of illustrations includes reproductions of iconic photographs by Richard Avedon, Eve Arnold, Gordon Parks, Henri Cartier-Bresson, and John Launois. Abernethy reveals that Malcolm X himself was keenly aware of the power of imagery to redefine identity and worked tirelessly to shape how he was represented to the public. His theoretical grasp of what he termed "the science of imagery" enabled him both to analyze the role of representation in ideological control as well as to exploit his own image in the interests of black empowerment. This provocative work marks a startling shift from the biographical focus that has dominated Malcolm X studies, providing an up-to-date--and comprehensively illustrated--account of Malcolm's cultural afterlife, and addressing his iconography in relation to images of other major African American figures, including Martin Luther King, Jr., Angela Davis, Kanye West, and Barack Obama. Analyzing the competing interpretations behind so many images, Abernethy reveals what our lasting obsession with Malcolm X says about American culture over the last five decades. (shrink)

This article enquires into the curriculum advocated in the only ancient Greek treatise concerning education that has survived in its entirety, entitled On the Training of Children. The treatise was highly influential in Europe from the Renaissance to the nineteenth century, and thus exhibits certain assumptions concerning the purpose of curriculum that lie behind the development of western education and may still be influential today. The inquiry is conducted in three stages: the intended recipients of the curriculum are identified; its (...) elements are enumerated and evaluated; and its aims are inferred from the text. I conclude that the curriculum was intended for wealthy, privileged boys, that philosophy (though not independent theorising) was the most valued subject of study and that the aim of the curriculum was to instil in the recipients aristocratic values and modes of behaviour. Finally, some topics are suggested for reflection, in response to these conclusions, upon existing curricula. (shrink)

Although the scientific method has reached deeply into our intellectual and social life, there are places where it stops short, where its limitations become evident to us all. In these cases we discover that science can go about its explanations in its usual way, but that it does not tell us anything very interesting, and especially not what we most want to know. Let us think of music and painting, drama and ballet. No doubt a scientific method can tell us (...) something about them, but nothing very important or enlightening, perhaps something about their acoustical or chromatic materials, or some sort of evolutionary background. The scientists who try to go further than that in their explanations of the arts have earned a reputation for being reductionist in the bad sense. It is also my view that the incompetence of science becomes evident when it is applied to the interpretation of law and religion, love and many other forms of human aspiration -- but I shall not argue that point here. For what I hope to show is that the study of an elementary, fundamental human experience, seeing, is best pursued by certain philosophical methods that are not what we call scientific. The same applies to hearing. Many scientific studies have been made of seeing and hearing, but in my view they have not succeeded in the way that philosophy has in revealing the true character of these experiences. I shall devote the first two sections of this paper to outlining one philosophical approach to seeing that I regard as successful -- an approach I develop by working through key sections of Heidegger's Being and Time -- and then, in the concluding section, I point to the defects that I believe mark the approach of psychology and cognitive science. (shrink)

Two challenges facing Archbishop John Bede Polding after arriving in Sydney in 1835 were providing for the spiritual needs of Catholics in the colony and managing their affairs in a way that attempted to guarantee a good working relationship with the government. It became apparent to Polding that education was fundamental in developing both these areas. Polding regarded education as a means of social advancement, beneficial to those 'on the lower steps of the social scale'. He wanted a 'native race (...) of priests and statesmen, of lawyers and physicians, of solicitors, and sailors, and artists'. He sought to emulate Downside Abbey's approach to education in Australia; specifically in the field of secondary education that would 'transcend the mere bread-and-butter preoccupations of the masses and prepare an 'elite' from among whom the offices of Church and state could eventually be filled'. Polding's goal was to create schools that would provide a Catholic education for its students founded on the principles of Benedictine ideals. But, as Francesca Fitz-Walter argues, it was the colonial conditions of the time that placed obstacles on Polding's expression of the Benedictine ideal in education. Given that the colonial conditions of the time imposed restrictions on the expression of the Benedictine ideal, Polding still maintained that a lifelong education was significant in developing in the student the ability to make an informed Christian response to whatever circumstance might emerge in the life of that person. (shrink)

In this particularly well written volume Graeme Hirst presents a theoretically motivated foundation for semantic interpretation (conceptual analysis) by computer, and shows how this framework facilitates the resolution of both lexical and syntactic ambiguities.

In this issue of the Hastings Center Report, Jason Wasserman and Mark Navin argue that patients without decisional capacity can still have relatively stable wishes or inclinations toward one treatment option over another and that these preferences are “not devoid of moral weight and might therefore guide or at least influence treatment decisions when they cannot be defeated by other considerations.” This position is not controversial among most bioethicists. The hard work comes in sussing out the details of this position. (...) How much moral weight do these preferences have? When should preferences be defeated by other considerations? How should we identify actual preferences, and how should preferences be differentiated and weighed against one another? (shrink)

"Graeme Nicholson addresses the fundamental topic of ontology, perhaps the fundamental topic posed to philosophy and the human mind: what is being?, i.e., what is it to exist or to be? He initially shows that we humans must be understood to be "existers" and "disclosers"--terms that render Heidegger's concept Dasein. Heidegger's philosophy provides the basic viewpoint, but Professor Nicholson offers an interpretation of Heidegger that seeks to set deconstructionist and pragmatist readings to one side. Since, according to Heidegger, being (...) is fundamentally a union of presence and absence, this study shows that metaphysical theories have always offered positive illustrations or interpretations of being." "Illustrations of Being then goes on to scrutinize the four most fundamental determinations of being that Western thought has adumbrated: being as substance, especially in Greek ontology; being as reality, especially in the period from Descartes to Kant, and therefore in nineteenth- and twentieth-century science; the logic of being, in which Nicholson undertakes an ontological critique of mathematical logic; and being as the transformation of form--the key idea that runs from Christian patristics, through Hegel and Marx, to modern dialectics." "Graeme Nicholson's new study is marked by its receptiveness to metaphysics in the traditional sense, and contains a critique of the deconstructionist effort to pass beyond metaphysics. It will be of interest to professional philosophers and to theologians, as well as to graduate students and to members of the general public interested in philosophical arguments about the nature of being."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved. (shrink)

The right not to know is a contested matter. This can be because the inversion of the normal framing of entitlement to information about one's own health is thought to be illogical and inconsistent with self-authorship and/or because the very idea of claiming a right not to know information is an inappropriate appeal to the discourse of rights that places impossible responsibilities on others. Notwithstanding, there has been a sustained increase in this kind of appeal in recent years fueled in (...) large part by the rise and rise of the importance of personal autonomy in health care ethics, and by domestic and international health law. The right not to know has been acknowledged in at least two important international legal instruments. For example, the UNESCO Universal Declaration on the Human Genome and Human Rights, Article 5c provides: “The right of every individual to decide whether or not to be informed of the results of genetic examination and the resulting consequences should be respected.”. (shrink)

We analyse aspects of the Big Bang program in modern cosmology, with special focus on the strategies employed by its adherents both in defending the theory against anomalous data and in dismissing rival accounts. We illustrate this by critically examining four aspects of Big Bang cosmology: the interpretation of the cosmic red-shift, the explanation of the cosmic background radiation, the inflation hypothesis and the search for dark matter. We conclude that the Big Bang's dominance of contemporary cosmology is not justified (...) by the degree of experimental support it receives relative to rival theories. (shrink)

Title: Walter Benjamin: Eine BiographiePublisher: Reinbek bei HamburgISBN: 3499126753Author: Werner FuldTitle: Spinne im Eigenen Netz. Walter Benjamin: Leben und WerkPublisher: ElsterISBN: 3891511027Author: Momme BrodersenTitle: Benjaminiana: Eine Biografische RecherchePublisher: Anabas-VerlagISBN: 3870381590Author: Hans Puttnies and Gary Smith.

The Analytical Marxian paradigm is motivated by a desire to make Marx's theory "clear." Its criteria for success in this venture are drawn from one tendency within contemporary analytical philosophy. The works of G.A. Cohen and Jon Elster on Marx are best understood in the light of this philosophical background. The ultimately fatal limitations of the analytical paradigm as a whole, and of its interpretation of Marx's theory of history in particular, are derived from a contradiction at this philosophical level: (...) Analytical Marxism attempts to make Marx's thought clear with a methodology which is fundamentally corrosive to the practical-active meaning of that thought. (shrink)

This article will explore the musicianship of Bishop Charles Henry Davis, osb, coadjutor to Australia's first Catholic Archbishop, John Bede Polding, osb. It will focus on his musical contribution to the early Australian Catholic Church-his ability to improvise, compose, conduct and perform during his short time as bishop at St Mary's, Sydney.

The Vivekacudamani is one of the most important texts in the Advaita tradition and the most popular philosophical work ascribed to the great Indian philosopher, Sankara. This book presents an accessible translation of the entire text and also includes Upanisadic cross-referencing to most of its 580 verses, extensive notes, a lengthy Introduction, list of variant readings, an extensive bibliography, and an index to the verses.

The programme of work -- Towards a theory of jokes -- The process of joke comprehension -- Text comprehension -- Processing and prediction -- Logic in jokes -- Incongruity and resolution -- Surprise -- The role of language -- Impropriety -- Superiority and aggression -- What's in a joke? -- Applying the framework -- The way forward.

Analytic philosophy has recently demonstrated a revived interest in metaphysical problems about possibility and necessity. Graeme Forbes here provides a careful description of the logical background of recent work in this area for those who may be unfamiliar with it, moving on to d discuss the distinction between modality de re and modality de dicto and the ontological commitments of possible worlds semantics. In addition, Forbes offers a unified theory of the essential properties of sets, organisms, artefacts, substances, and (...) events, based on the doctrine that identity facts must be intrinsically grounded, and analyzes and rejects apparent counterexamples to this doctrine. (shrink)

Discussion of uses of biomedical data often proceeds on the assumption that the data are generated and shared solely or largely within the health sector. However, this assumption must be challenged because increasingly large amounts of health and well-being data are being gathered and deployed in cross-sectoral contexts such as social media and through the internet of things and wearable devices. Cross-sectoral sharing of data thus refers to the generation, use and linkage of biomedical data beyond the health sector. This (...) paper considers the challenges that arise from this phenomenon. If we are to benefit fully, it is important to consider which ethical values are at stake and to reflect on ways to resolve emerging ethical issues across ecosystems where values, laws and cultures might be quite distinct. In considering such issues, this paper applies the deliberative balancing approach of the Ethics Framework for Big Data in Health and Research to the domain of cross-sectoral big data. Please refer to that article for more information on how this framework is to be used, including a full explanation of the key values involved and the balancing approach used in the case study at the end. (shrink)