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  1.  16
    Proceedings of the Seventh Annual Deep Brain Stimulation Think Tank: Advances in Neurophysiology, Adaptive DBS, Virtual Reality, Neuroethics and Technology.Adolfo Ramirez-Zamora, James Giordano, Aysegul Gunduz, Jose Alcantara, Jackson N. Cagle, Stephanie Cernera, Parker Difuntorum, Robert S. Eisinger, Julieth Gomez, Sarah Long, Brandon Parks, Joshua K. Wong, Shannon Chiu, Bhavana Patel, Warren M. Grill, Harrison C. Walker, Simon J. Little, Ro’ee Gilron, Gerd Tinkhauser, Wesley Thevathasan, Nicholas C. Sinclair, Andres M. Lozano, Thomas Foltynie, Alfonso Fasano, Sameer A. Sheth, Katherine Scangos, Terence D. Sanger, Jonathan Miller, Audrey C. Brumback, Priya Rajasethupathy, Cameron McIntyre, Leslie Schlachter, Nanthia Suthana, Cynthia Kubu, Lauren R. Sankary, Karen Herrera-Ferrá, Steven Goetz, Binith Cheeran, G. Karl Steinke, Christopher Hess, Leonardo Almeida, Wissam Deeb, Kelly D. Foote & Okun Michael S. - 2020 - Frontiers in Human Neuroscience 14.
  2.  3
    Local Anatomy, Stimulation Site, and Time Alter Directional Deep Brain Stimulation Impedances.Joseph W. Olson, Christopher L. Gonzalez, Sarah Brinkerhoff, Maria Boolos, Melissa H. Wade, Christopher P. Hurt, Arie Nakhmani, Bart L. Guthrie & Harrison C. Walker - 2022 - Frontiers in Human Neuroscience 16.
    Directional deep brain stimulation contacts provide greater spatial flexibility for therapy than traditional ring-shaped electrodes, but little is known about longitudinal changes of impedance and orientation. We measured monopolar and bipolar impedance of DBS contacts in 31 patients who underwent unilateral subthalamic nucleus deep brain stimulation as part of a randomized study. At different follow-up visits, patients were assigned new stimulation configurations and impedance was measured. Additionally, we measured the orientation of the directional lead during surgery, immediately after surgery, and (...)
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  3. Walking Speed Reliably Measures Clinically Significant Changes in Gait by Directional Deep Brain Stimulation.Christopher P. Hurt, Daniel J. Kuhman, Barton L. Guthrie, Carla R. Lima, Melissa Wade & Harrison C. Walker - 2021 - Frontiers in Human Neuroscience 14.
    Introduction: Although deep brain stimulation often improves levodopa-responsive gait symptoms, robust therapies for gait dysfunction from Parkinson's disease remain a major unmet need. Walking speed could represent a simple, integrated tool to assess DBS efficacy but is often not examined systematically or quantitatively during DBS programming. Here we investigate the reliability and functional significance of changes in gait by directional DBS in the subthalamic nucleus.Methods: Nineteen patients underwent unilateral subthalamic nucleus DBS surgery with an eight-contact directional lead in the most (...)
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