Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

The theme of the third annual Spring workshop of the HUPO-PSI was proteomics and beyond and its underlying goal was to reach beyond the boundaries of the proteomics community to interact with groups working on the similar issues of developing interchange standards and minimal reporting requirements. Significant developments in many of the HUPO-PSI XML interchange formats, minimal reporting requirements and accompanying controlled vocabularies were reported, with many of these now feeding into the broader efforts of the Functional Genomics Experiment data (...) model and Functional Genomics Ontology ontologies. (shrink)

This essay describes a problem, that German protestant theology has faced for nearly a hundred years. The problem derives from a theory of death, which spread among theologians in the first decades of the 20th century. In contradiction to traditional doctrine they interpreted death not as the moment, when the immortal soul seperates from the body, but as the moment in time, when human life comes to its absolute end. That means, they denied the idea of an immortal soul. Accordingly (...) they interpreted the resurrection of the dead as a radically new creation. This theory, named Ganztodtheorie, caused an unsolvable problem, that can be described as follows: How can one be sure, that it is exactely he, who becomes resurrected and not a newly created double? Christian Henning discusses the answers to this question, that had been given by Carl Stange, Paul Althaus, Werner Elert, Karl Barth, Eberhard Jüngel and Wolfhard Pannenberg and finally presents his own solution. In doing so he modifies the traditional idea of the immortality of the soul. (shrink)

A central concern of nearly every environmental ethic is its desire to extend the scope of direct moral concern beyond human beings to plants, nonhuman animals, and the systems of which they are a part. Although nearly all environmental philosophies have long since rejected modernity’s conception of individuals as isolated and independent substances, few have replaced this worldview with an alternative that is adequate to the organic, processive world in which we find ourselves. In this context, Brian G. Henning (...) argues that the often overlooked work of Alfred North Whitehead has the potential to make a significant contribution to environmental ethics. Additionally inspired by classical American philosophers such as William James, John Dewey and Charles Sanders Pierce and environmental philosophers such as Aldo Leopold, Peter Singer, Albert Schweitzer, and Arne Naess, Henning develops an ethical theory of which the seminal insight is called “The Ethics of Creativity.” By systematically examining and developing a conception of individuality that is equally at home with the microscopic world of subatomic events and the macroscopic world of ecosystems, _The Ethics of Creativity_ correctly emphasizes the well-being of wholes, while not losing sight of the importance of the unique centers of value that constitute these wholes. In this way, _The Ethics of Creativity_ has the potential to be a unique voice in contemporary moral philosophy. (shrink)

A central concern of nearly every environmental ethic is its desire to extend the scope of direct moral concern beyond human beings to plants, nonhuman animals, and the systems of which they are a part. Although nearly all environmental philosophies have long since rejected modernity’s conception of individuals as isolated and independent substances, few have replaced this worldview with an alternative that is adequate to the organic, processive world in which we find ourselves. In this context, Brian G. Henning (...) argues that the often overlooked work of Alfred North Whitehead has the potential to make a significant contribution to environmental ethics. Additionally inspired by classical American philosophers such as William James, John Dewey and Charles Sanders Pierce and environmental philosophers such as Aldo Leopold, Peter Singer, Albert Schweitzer, and Arne Naess, Henning develops an ethical theory of which the seminal insight is called “The Ethics of Creativity.” By systematically examining and developing a conception of individuality that is equally at home with the microscopic world of subatomic events and the macroscopic world of ecosystems, _The Ethics of Creativity_ correctly emphasizes the well-being of wholes, while not losing sight of the importance of the unique centers of value that constitute these wholes. In this way, _The Ethics of Creativity_ has the potential to be a unique voice in contemporary moral philosophy. (shrink)

Many authors in ethics, economics, and political science endorse the Lottery Requirement, that is, the following thesis: where different parties have equal moral claims to one indivisible good, it is morally obligatory to let a fair lottery decide which party is to receive the good. This article defends skepticism about the Lottery Requirement. It distinguishes three broad strategies of defending such a requirement: the surrogate satisfaction account, the procedural account, and the ideal consent account, and argues that none of these (...) strategies succeed. The article then discusses and discharges some remaining grounds for resistance to these skeptical conclusions, as well as the possibility of defending a weaker version of a normative lottery principle. The conclusion is that we have no reason to believe that where equal claims conflict, we are morally required to hold a lottery, as opposed to simply picking one of the parties on more subjective grounds or out of pure whim. In addition to the practical consequences of this skeptical view, the article sketches some theoretical implications for debates about saving the greater number and about axiomatic utilitarianism. (shrink)

This article argues for the view that statements about normative reasons are context-sensitive. Specifically, they are sensitive to a contextual parameter specifying a relevant person's or group's body of information. The argument for normative reasons contextualism starts from the context-sensitivity of the normative “ought” and the further premise that reasons must be aligned with oughts. It is incoherent, I maintain, to suppose that someone normatively ought to φ but has most reason not to φ. So given that oughts depend on (...) context, a parallel view about normative reasons is needed. It is shown that the resulting view solves notorious puzzles involving apparently conflicting but equally plausible claims about reasons. These puzzles arise especially in cases where agents have limited information or false beliefs. In these cases, we feel torn between reasons claims that take into account the limitations of the agent's perspective and apparently conflicting claims that are made from a more objective point of view. The contextualist account developed here accommodates both objectivist and subjectivist intuitions. It shows that all of the claims in question can be true, provided that they are relativized to different values of the relevant information parameter. Also, contextualism yields a fruitful approach to the debate about having reasons and the alleged failure of the so-called “factoring account”. (shrink)

Moral realists can, and should, allow that the truth-conditional content of moral judgments is in part attitudinal. I develop a two-dimensional semantics that embraces attitudinal content while preserving realist convictions about the independence of moral facts from our attitudes. Relative to worlds “considered as counterfactual,” moral terms rigidly track objective, response-independent properties. But relative to different ways the actual world turns out to be, they nonrigidly track whatever properties turn out to be the objects of our relevant attitudes. This theory (...) provides realists with a satisfactory account of Moral Twin Earth cases and an improved response to Blackburn’s supervenience argument. (shrink)

It has been said that new discoveries and developments in the human, social, and natural sciences hang “in the air” (Bowler, 1983; 2008) prior to their consummation. While neo-Darwinist biology has been powerfully served by its mechanistic metaphysic and a reductionist methodology in which living organisms are considered machines, many of the chapters in this volume place this paradigm into question. Pairing scientists and philosophers together, this volume explores what might be termed “the New Frontiers” of biology, namely contemporary areas (...) of research that appear to call an updating, a supplementation, or a relaxation of some of the main tenets of the Modern Synthesis. Such areas of investigation include: Emergence Theory, Systems Biology, Biosemiotics, Homeostasis, Symbiogenesis, Niche Construction, the Theory of Organic Selection (also known as “the Baldwin Effect”), Self-Organization and Teleodynamics, as well as Epigenetics. Most of the chapters in this book offer critical reflections on the neo-Darwinist outlook and work to promote a novel synthesis that is open to a greater degree of inclusivity as well as to a more holistic orientation in the biological sciences. (shrink)

A primary contribution of this essay is to provide a survey of the human and environmental impacts of livestock production. We will find that the mass consumption of animals is a primary reason why humans are hungry, fat, or sick and is a leading cause behind the depletion and pollution of waterways, the degradation and deforestation of the land, the extinction of species, and the warming of the planet. Recognizing these harms, this essay will consider various solutions being proposed to (...) “shrink” livestock’s long shadow, including proposed “technical” or “market” solutions, a transition to “new agrarian” methods, and a vegetarian or vegan diet. Though important and morally relevant qualitative differences exist between industrial and non-industrial methods, this essay will conclude that, given the present and projected size of the human population, the morality and sustainability of one’s diet are inversely related to the proportion of animals and animal products one consumes. (shrink)

Harry Frankfurt has claimed that some of our desires are ‘internal’, i.e., our own in a special sense. I defend the idea that a desire's being internal matters in a normative, reasons-involving sense, and offer an explanation for this fact. The explanation is Kantian in spirit. We have reason to respect the desires of persons in so far as respecting them is a way to respect the persons who have them (in some cases, ourselves). But if desires matter normatively in (...) so far as they belong to persons, then it matters whether they really do belong to the persons who have them. Thus Kantian considerations explain why identification (or internality) is a normatively relevant category. This account is superior to others, and does not lead to reasons bootstrapping or a self-centred conception of deliberation. (shrink)

In this article the work of a recent critic of moral vegetarianism is analyzed: Andrew F. Smith. Smith s work is significant for process thinkers who defend moral vegetarianism for various reasons. One of these is that he forces process thinkers to consider in more depth Whitehead’s view of plant ontology; another is that Smith adds insightfully to the conversation within process thought regarding the relationship between claims regarding animal rights and the ecoholistic concerns of environmental ethicists.

Is there an ethics of creativity? Though this question appears innocent enough, it proves surprisingly difficult to answer. A survey of the literature on the topic reveals that process ethics has variously been categorized as or seen as compatible with: moral interest theory, ecological virtue ethics, utilitarianism, Confucian virtue ethics, and even deontology. What can account for such divergent and even contradictory conclusions? On one level we might blame Whitehead, whose sporadic comments on morality may appear to be more suggestive (...) than systematic. While, as I argue elsewhere,3 there is a greater coherence to Whitehead’s statements about morality than is initially apparent, it is undeniable that he never attempted to develop a theory of morality. Yet it is unlikely that the state of the texts should shoulder all of the blame for the lack of consensus on the basic nature of process ethics. It would seem that there is a more fundamental problem lurking beneath the surface. Indeed, I suggest that there are at least five basic confusions — four substantive and one methodological — that have vitiated attempts to understand and develop a process approach to morality. Until these confusions are recognized and resolved, we will have no hope of understanding the promise or realizing the potential of the ethics of creativity. (shrink)

As the collective impact of human activity approaches Earth’s biophysical limits, the ethics of food become increasingly important. Hundreds of millions of people remain undernourished, yet only 60 percent of the global harvest is consumed by humans, while 35 percent is fed to livestock and 5 percent is used for biofuels and other industrial products. This essay considers the ethics of such use of edible nutrition for feedstock and biofuel. How humanity uses Earth’s land is a reflection of its values. (...) The current land-use arrangements, which divert 40 percent of all food to feed animals or create fuels, suggest that dietary and transportation preferences of wealthier individuals are considered more important than feeding undernourished people, or the stability of the wider biotic community. (shrink)

Although debates over carbon taxes and trading schemes, over carbon offsets and compact fluorescents are important, our efforts to address the environmental challenges that we face will fall short unless and until we also set about the difficult work of reconceiving who we are and how we are related to our processive cosmos. What is needed, I argue, are new ways of thinking and acting grounded in new ways of understanding ourselves and our relationship to the world, ways of understanding (...) that recognize our fundamental interdependence and interconnection with everyone and everything in the cosmos, ways of understanding that recognize the intrinsic beauty and value of every form of existence. What is needed, I suggest, is a moral philosophy grounded in Alfred North Whitehead's philosophy of organism. It is the primary aim of this essay to defend the value of a moral philosophy inspired by Whitehead's organic, beauty-centered conception of reality. (shrink)

This paper explores Kant’s views about the logical form of “I think”-judgments. It is shown that according to Kant, in an important class of cases the prefix “I think” does not contribute to the assertoric, truth-conditional content of judgments of the form “I think that P.” Thus, judgments of this type are often merely judgments that P. The prefix “I think” does mention the subject and his thought, but it does not make the complex judgment a judgment about the subject (...) and his or her thought. Kant argues that there is a distinctive kind of self-consciousness that is adequately expressed by means of this non-assertoric “I think.” The paper explains that understanding Kant’s ideas on the logic of “I think”-judgments is fruitful both for discussions in contemporary analytic philosophy and for an adequate understanding of Kant’s philosophy. (shrink)

Recent welfare reform has resulted in new work requirements for welfare recipients. These measures need to be justified, as they impair recipients’ freedom. This paper first repudiates economic justifications for these developments and argues that the dominant justification is perfectionist. But unlike workfare, perfectionism is not necessarily paternalistic. The second part of the paper outlines a liberal perfectionism which allows only for autonomy-enhancing politics. Though even such autonomy-enhancing politics cannot be made obligatory. The last section concludes that workfare’s paternalism cannot (...) be attributed to perfectionist justifications, but rather stems from the narrow philosophy of work that is applied. The idea that enforced wage labour is a reliable tool for inducing autonomy is refuted. In the end, workfare needs to be rejected, as it is based on assumptions that are mistaken both normatively and empirically. (shrink)

Perfectionism is a new player in the field of political philosophy. It is often rejected by liberal philosophers for it seems to have a conservative or paternalist bias. However, this paper argues first that perfectionism can have different political tendencies: it can be both liberal and illiberal, equalizing or anti-egalitarian, and be based on both limited or open conceptions of human nature. So perfectionism is not intrinsically conservative. Secondly, the paper aims to show that a strong case can be made (...) for a liberal and egalitarian perfectionism, based on a rereading of Karl Marx. From this perspective it is not only unnecessary to criticize perfectionism from a liberal or egalitarian perspective, perfectionism may also help in justifying liberal egalitarianism in a new way. (shrink)

My goal in this brief essay is not so much to defend White's controversial thesis, but to use it as a context for appreciating the significance of Pope Francis's new encyclical Laudato Si’. Considering it in the context of White’s thesis, will bring certain salient features into relief.

The aim of this essay is twofold. First, I examine the role of Alfred North Whitehead and process thinkers in bringing about and shaping the field of environmental ethics. As we will see, our job is not so much to develop the connections between Whitehead and environmental thought as to recover them. Second, given this genealogical work, I invite process scholars to reconsider their generally hostile reception of Aldo Leopold and his land ethic. I suggest that a version of the (...) land ethic grounded in a process axiology could make a significant contribution to contemporary environmental thought. (shrink)

The paper describes supportive actions for users of NC machine tools. From the technical point of view, this comprises new input/output media for interaction with the machine as well as new software tools for help systems. From the organisational point of view, concepts for group work are to be supported and a methology for participation of users in the development process is suggested. A software tool for job order planning is presented which combines organisational and technical aspects. One of the (...) aims of the research reported here, is to explore options of systems which keep the human expert in the loop of shopfloor production. (shrink)

Definition of the problem The creation and selection of children as tissue donors is ethically controversial. Critics often appeal to Kant’s Formula of Humanity, i.e. the requirement that people be treated not merely as means but as ends in themselves. As many defenders of the procedure point out, these appeals usually do not explain the sense of the requirement and hence remain obscure. Arguments This article proposes an interpretation of Kant’s principle, and it proposes that two different instrumental stances be (...) distinguished. I argue that the creation of “saviour children” is a form of instrumentalization that I dub “preemptive instrumentalization” and that it is categorically different from earlier forms of instrumental attitudes concerning human reproduction. Conclusion Critics are wrong to claim that Kant’s principle is either compatible with the selection of saviour siblings or too vague to serve as an ethical principle. (shrink)

While most scholars readily recognize that Alfred North Whitehead had deep and penetrating misgivings about the substantial view of individuality, fewer note that these misgivings stem as much from axiological considerations as ontological ones. I contend that, taken in the context of the “classical interpretation” of his metaphysics, Whitehead’s bold affirmation that actuality and value are coextensive introduces a potentially serious problem for the adequacy and applicability of his axiology. For if actuality is coextensive with valuebut actuality is itself limited (...) to subjects of experience, then the objective world can have no intrinsic value. My aim is to demonstrate that, in order to respond to the very serious challenge which the problem of subjectivism represents and save Whitehead’s intendeduniverse of value, we must seek an alternative to the classical interpretation of Whitehead’s metaphysics. I refer to this alternative as the “ecstatic interpretation.”. (shrink)

Strategies to involve agribusiness in the development of sustainable agricultural systems have been limited by the lack of a comprehensive conceptual framework for identifying the most critical supportive policies, programs and regulations. In this paper, we propose an efficiency/substitution/redesign framework to categorize strategies for modifying agribusiness practices. This framework is then used to identify a diverse range of short, medium, and long-term strategies to be pursued by governments, community groups, academics and agribusiness to support the transition. Strategies discussed include corporate (...) greening, ethical investment, changing the legal status of the corporaton, new business forms and the development of ecological economics. (shrink)

My aim in this article is twofold. First, I hope to show that, despite its seeming rehabilitation, metaphysics as systematic, speculative philosophy is no less threatened. Second, I will argue that metaphysics as systematic, speculative philosophy is ultimately revisable. That is, metaphysics is not (or should not be) the aim at a closed system of apodictic truths but, rather, an open-ended, fallibilistic pursuit of ever- more-adequate accounts of reality. Specifically, building on the work of Charles Sanders Peirce and Alfred North (...) Whitehead, I will argue that we should conceive of metaphysics not as the quest for absolute certainty but as “working hypothesis.” Thus, the first part will be largely historical and critical, and the second part will be positive and exploratory. (shrink)

This paper argues that a certain kind of alienation from labour can be analyzed and explained in the theoretical framework that is dominant in current economics. Given a neoclassical model of a labour market, the intrinsic value that different kinds of labour may have for people can be represented as a source of utility (in the technical sense). It can then be shown that in capitalist economies, basing one’s supply decisions on this intrinsic value is predictably costly. So in the (...) long run, rational agents can be – and will be – expected to make their labour supply decisions based only on considerations of income and leisure time. In the resulting picture, rational agents are indifferent with regard to different qualitatively specific kinds of labour. I draw on the theory of efficiency wages to show that this picture lies at the root of contemporary problems like involuntary unemployment and injustice. (shrink)