This collects some of the remarks made at the 2016 Pacific APA Memorial session for Patrick Suppes and Jaakko Hintikka. The full list of speakers on behalf of these two philosophers: Dagfinn Follesdal; Dana Scott; Nancy Cartwright; Paul Humphreys; Juliet Floyd; Gabriel Sandu; John Symons.
Van den Dries, L. and J. Holly, Quantifier elimination for modules with scalar variables, Annals of Pure and Applied Logic 57 161–179. We consider modules as two-sorted structures with scalar variables ranging over the ring. We show that each formula in which all scalar variables are free is equivalent to a formula of a very simple form, uniformly and effectively for all torsion-free modules over gcd domains . For the case of Presburger arithmetic with scalar variables the result takes (...) a still simpler form, and we derive in this way the polynomial-time decidability of the sets defined by such formulas. (shrink)
We have synthesized a 582,970-base pair Mycoplasma genitalium genome. This synthetic genome, named M. genitalium JCVI-1.0, contains all the genes of wild-type M. genitalium G37 except MG408, which was disrupted by an antibiotic marker to block pathogenicity and to allow for selection. To identify the genome as synthetic, we inserted "watermarks" at intergenic sites known to tolerate transposon insertions. Overlapping "cassettes" of 5 to 7 kilobases (kb), assembled from chemically synthesized oligonucleotides, were joined by in vitro recombination to produce intermediate (...) assemblies of approximately 24 kb, 72 kb ("1/8 genome"), and 144 kb ("1/4 genome"), which were all cloned as bacterial artificial chromosomes in Escherichia coli. Most of these intermediate clones were sequenced, and clones of all four 1/4 genomes with the correct sequence were identified. The complete synthetic genome was assembled by transformation-associated recombination cloning in the yeast Saccharomyces cerevisiae, then isolated and sequenced. A clone with the correct sequence was identified. The methods described here will be generally useful for constructing large DNA molecules from chemically synthesized pieces and also from combinations of natural and synthetic DNA segments. 10.1126/science.1151721. (shrink)
There are differences between human beings, and some of these differences are, for many, a matter of identity. Some people are men, and some are white. Some people are poor, others are wealthy. These identity-constituting differences are deeply connected with different kinds of injustices. Susan Hekman's main contention in The Future of Differences is that a new epistemology is required if we are to acknowledge all these differences and, consequently, address these injustices.
Jack Reynolds has written Merleau-Ponty and Derrida, coedited Understanding Derrida, taught at the Central Institute of Higher Tibetan Studies, and shaken hands with HHDL. He remains in the realm of samsara.
Schneiderman, Teetzel, and Gilmer offer an amusing but misleading response to my article on medical futility. Although I did make note of the falloff in citations to medical futility in Medline and Bioethicsline after 1995, my analysis focused on the precipitous rise in professional publications on the concept in the period from 1988 to 1995—a trend confirmed by the authors' own search results. I certainly did not argue, either explicitly or implicitly, that the discussion of medical futility was over. I (...) made limited use of this citation survey—to raise a question about what sparked so much professional debate after 1988. This seems to me an entirely appropriate methodology. (shrink)