Results for 'Human experimentation in medicine Moral and ethical aspects'

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  1. The Ethics and Politics of Human Experimentation.Paul Murray McNeill - 1993 - Cambridge University Press.
    This book focuses on experimentation that is carried out on human beings, including medical research, drug research and research undertaken in the social sciences. It discusses the ethics of such experimentation and asks the question: who defends the interests of these human subjects and ensures that they are not harmed? The author finds that ethical research depends on the adequacy of review by committee. Indeed most countries now rely on research ethics committees for the protection (...)
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  2.  18
    Ethical and Regulatory Aspects of Clinical Research: Readings and Commentary.Ezekiel J. Emanuel (ed.) - 2003 - Johns Hopkins University Press.
    All investigators funded by the National Institutes of Health are now required to receive training about the ethics of clinical research. Based on a course taught by the editors at NIH, Ethical and Regulatory Aspects of Clinical Research is the first book designed to help investigators meet this new requirement. The book begins with the history of human subjects research and guidelines instituted since World War II. It then covers various stages and components of the clinical trial (...)
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  3.  5
    Evaluating the Science and Ethics of Research on Humans: A Guide for Irb Members.Dennis John Mazur - 2007 - Johns Hopkins University Press.
    Biomedical research on humans is an important part of medical progress. But, when lives are at risk, safety and ethical practices need to be the top priority. The need for the committees that regulate and oversee such research -- institutional review boards, or IRBs -- is growing. IRB members face difficult decisions every day. Evaluating the Science and Ethics of Research on Humans is a guide for new and veteran members of IRBs that will help them better understand the (...)
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  4.  73
    Ethics and Regulation of Clinical Research.Robert J. Levine - 1986 - Urban & Schwarzenberg.
    In this book, Dr. Robert J. Levine reviews federal regulations, ethical analysis, and case studies in an attempt to answer these questions.
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  5. Science and Ethics.Bernard E. Rollin - 2006 - Cambridge University Press.
    In Science and Ethics, Bernard Rollin examines the ideology that denies the relevance of ethics to science. Providing an introduction to basic ethical concepts, he discusses a variety of ethical issues that are relevant to science and how they are ignored, to the detriment of both science and society. These include research on human subjects, animal research, genetic engineering, biotechnology, cloning, xenotransplantation, and stem cell research. Rollin also explores the ideological agnosticism that scientists have displayed regarding subjective (...)
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  6. The Limits of Consent: A Socio-Ethical Approach to Human Subject Research in Medicine.Oonagh Corrigan (ed.) - 2009 - Oxford University Press.
    Since its inception as an international requirement to protect patients and healthy volunteers taking part in medical research, informed consent has become the primary consideration in research ethics. Despite the ubiquity of consent, however, scholars have begun to question its adequacy for contemporary biomedical research. This book explores this issue, reviewing the application of consent to genetic research, clinical trials, and research involving vulnerable populations. For example, in genetic research, information obtained from an autonomous research participant may have significant bearing (...)
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  7.  12
    A Decent Proposal: Ethical Review of Clinical Research.Donald Evans - 1996 - Wiley.
    A Decent Proposal: Ethical Review of Clinical Research Donald Evans and Martyn Evans Centre for Philosophy and Health Care University of Wales Swansea, UK The investigation and development of modern medicines and medical technology can create numerous ethical dilemmas both for clinical researchers and research ethics committees. A Decent Proposal: Ethical Review of Clinical Research seeks to facilitate and encourage good clinical research by exploring the concerns, responsibilities, general issues and particular pitfalls associated with ethical (...) of research. It provides practical guidelines for researchers on how to improve the quality of research design, while for those appointed to scrutinise research proposals it offers advice on how to apply consistent, careful and critical reasoning to the process of assessing ethical standards. As such, it will provide invaluable assistance to clinical researchers and ethics committees alike in understanding the moral challenges posed by modern health care. (shrink)
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  8.  97
    Ethics in Medical Research: A Handbook of Good Practice.Trevor Smith - 1999 - Cambridge University Press.
    This is a comprehensive and practical guide to the ethical issues raised by different kinds of medical research, and is the first such book to be written with the needs of the researcher in mind. Clearly structured and written in a plain and accessible style, the book covers every significant ethical issue likely to be faced by researchers and research ethics committees. The author outlines and clarifies official guidelines, gives practical advice on how to adhere to these, and (...)
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  9. The Oxford Textbook of Clinical Research Ethics.Ezekiel J. Emanuel (ed.) - 2008 - Oxford University Press.
    Comprehensive in scope and research, this book will be a crucial resource for researchers in the medical sciences, as well as teachers and students alike.
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  10.  9
    Research on Human Subjects: Ethics, Law and Social Policy.David N. Weisstub (ed.) - 1998 - Pergamon Press.
    There have been serious controversies in the latter part of the 20th century about the roles and functions of scientific and medical research. In whose interests are medical and biomedical experiments conducted and what are the ethical implications of experimentation on subjects unable to give competent consent? From the decades following the Second World War and calls for the global banning of medical research to the cautious return to the notion that in controlled circumstances, medical research on (...) subjects is in the best interest of the given individual and the broader population, this book addresses the key implications of experimentation on humans. This volume covers major ethical themes within biomedical research providing historical, philosophical, legal and policy reflections on the literature and specific issues in the field of research on human subjects. Focusing on special populations (the elderly, children, prisoners and the cognitively impaired) it represents the most up-to-date review of the special ethical and legal conflicts that arise with relation to experimentation on subjects from these groups. In the light of current initiatives for law reform pertaining to research ethics the world over, this volume provides a timely, comprehensive and provocative exploration of the field. The volume has been carefully organized to present important philosophical perspectives on organizing principles that should underlie any practical application. A forward-looking historical review of the regulatory regimes of principal jurisdictions, including of the legal controls already in place, provides the backdrop for future policy initiatives. Additionally, in the light of global restructuring of health care systems, several chapters have been devoted to epidemiological research and related issues. (shrink)
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  11.  9
    The Ethics of Fetal Research.Paul Ramsey - 1975 - Yale University Press.
    "The Ethics of Fetal Research" distinguishes between the legal and ethical questions raised by experimentation on still-living human fetuses.
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  12.  37
    Women and Health Research: Ethical and Legal Issues of Including Women in Clinical Studies.Anna C. Mastroianni, Ruth R. Faden & Daniel D. Federman (eds.) - 1994 - National Academy Press.
    Executive Summary There is a general perception that biomedical research has not given the same attention to the health problems of women that it has given ...
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  13.  65
    Research Ethics.Ana Smith Iltis (ed.) - 2005 - Routledge.
    Medicine in the twenty-first century is increasingly reliant on research to guarantee the safety and efficacy of medical interventions. As a result, the need to understand the ethical issues that research generates is becoming essential. This volume introduces the principal areas of concern in research on human subjects, offering a framework for understanding research ethics, and the relationship between ethics and compliance. Research Ethics brings together leading scholars in bioethics and the topics covered include the unique concerns (...)
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  14.  57
    Ethical Issues in International Biomedical Research: A Casebook.James V. Lavery (ed.) - 2007 - Oxford University Press.
    No other volume has this scope. Students in bioethics, public and international health, and ethics will find this book particularly useful.
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  15.  13
    Research Ethics Aspects of Experimentation with LSD on Human Subjects: A Historical and Ethical Review.Kristóf János Bodnár & Péter Kakuk - 2019 - Medicine, Health Care and Philosophy 22 (2):327-337.
    In this paper our aim is to examine whether research conducted on human participants with LSD-25 raises unique research ethical questions or demands particular concerns with regard to the design, conduct and follow-up of these studies, and should this be the case, explore and describe those issues. Our analysis is based on reviewing publications up to date which examine the clinical, research and other uses of LSD and those addressing ethical and methodological concerns of these applications, just (...)
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  16.  70
    Responsible Conduct of Research.Adil E. Shamoo - 2009 - Oxford University Press.
    Scientific research and ethics -- Ethical theory and decision making -- Data acquisition and management -- Mentoring and professional relationship -- Collaboration in research -- Authorship -- Publication and peer review -- Misconduct in research -- Intellectual property -- Conflicts of interest and scientific objectivity -- The use of animals in research -- The use of human subjects in research -- The use of vulnerable subjects in research -- Genetics, cloning, and stem cell research -- International research.
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  17.  78
    The Ethics of Biomedical Research: An International Perspective.Baruch A. Brody - 1998 - Oxford University Press.
    A broad critical review of national policies on biomedical research - human, epidemiologic, clinical trials, genetic, reproductive, etc.
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  18.  2
    Human Subjects in Medical Experimentation: A Sociological Study of the Conduct and Regulation of Clinical Research.Bradford H. Gray - 1981 - R.E. Krieger Pub. Co..
  19.  44
    Standing on Principles: Collected Essays.Tom L. Beauchamp - 2010 - Oxford University Press.
    This volume will collect Tom Beauchamp's 15 most important published articles in bioethics, most of which were published over the last 25 years, and most of ...
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  20.  1
    Research for Health Professionals: Design, Analysis, and Ethics.Robert Proulx Heaney - 1988 - Iowa State University Press.
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  21.  13
    Failed Surrogate Conceptions: Social and Ethical Aspects of Preconception Disruptions During Commercial Surrogacy in India.Sayani Mitra & Silke Schicktanz - 2016 - Philosophy, Ethics, and Humanities in Medicine 11:9.
    BackgroundDuring a commercial surrogacy arrangement, the event of embryo transfer can be seen as the formal starting point of the arrangement. However, it is common for surrogates to undergo a failed attempt at pregnancy conception or missed conception after an embryo transfer. This paper attempts to argue that such failed attempts can be understood as a loss. It aims to reconstruct the experiences of loss and grief of the surrogates and the intended parents as a consequence of their collective failure (...)
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  22.  26
    Evidence, Ethos and Experiment: The Anthropology and History of Medical Research in Africa.Wenzel Geissler & Catherine Molyneux (eds.) - 2011 - Berghahn Books.
    "This is an extremely interesting and innovative collection with unusual empirical richness, with ethical and epistemological discussions cutting across ...
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  23. Justice at Nuremberg: Leo Alexander and the Nazi Doctors' Trial.Ulf Schmidt - 2004 - Palgrave-Macmillan.
    Justice at Nuremberg traces the history of the Nuremberg Doctors' Trial held in 1946-47, as seen through the eyes of the Austrian bliogemigrbliogé psychiatrist Leo Alexander. His investigations helped the United States to prosecute twenty German doctors and three administrators for war crimes and crimes against humanity. The legacy of Nuremberg was profound. In the Nuremberg code--a landmark in the history of modern medical ethics--the judges laid down, for the first time, international guidelines for permissible experiments on humans. One of (...)
     
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  24. Against Relativism: Cultural Diversity and the Search for Ethical Universals in Medicine.Ruth Macklin - 1999 - Oxford University Press.
    This book provides an analysis of the debate surrounding cultural diversity, and attempts to reconcile the seemingly opposing views of "ethical imperialism," the belief that each individual is entitled to fundamental human rights, and cultural relativism, the belief that ethics must be relative to particular cultures and societies. The author examines the role of cultural tradition, often used as a defense against critical ethical judgments. Key issues in health and medicine are explored in the context of (...)
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  25.  19
    Healthcare Research Ethics and Law: Regulation, Review and Responsibility.Hazel Biggs - 2009 - Routledge-Cavendish.
    The book explores and explains the relationship between law and ethics in the context of medically related research in order to provide a practical guide to understanding for members of research ethics committees (RECs), professionals involved with medical research and those with an academic interest in the subject.
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  26. Ethical Constraints and Imperatives in Medical Research.Maurice B. Visscher - 1975 - Thomas.
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  27.  16
    Behind Closed Doors: Irbs and the Making of Ethical Research.Laura Jeanine Morris Stark - 2011 - University of Chicago Press.
    IRBs in action -- Everyone's an expert? Warrants for expertise -- Local precedents -- Documents and deliberations: an anticipatory perspective -- Setting IRBs in motion in Cold War America -- An ethics of place -- The many forms of consent -- Deflecting responsibility -- Conclusion: the making of ethical research.
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  28.  49
    Psychosocial and Ethical Aspects in Non-Invasive EEG-Based BCI Research—A Survey Among BCI Users and BCI Professionals.Gerd Grübler, Abdul Al-Khodairy, Robert Leeb, Iolanda Pisotta, Angela Riccio, Martin Rohm & Elisabeth Hildt - 2014 - Neuroethics 7 (1):29-41.
    In this paper, the results of a pilot interview study with 19 subjects participating in an EEG-based non-invasive brain–computer interface (BCI) research study on stroke rehabilitation and assistive technology and of a survey among 17 BCI professionals are presented and discussed in the light of ethical, legal, and social issues in research with human subjects. Most of the users were content with study participation and felt well informed. Negative aspects reported include the long and cumbersome preparation procedure, (...)
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  29. Vivisection, Morals and Medicine.R. G. Frey - 1983 - Journal of Medical Ethics 9 (2):94-97.
    If one wishes to accept that some painful animal experimentation can be justified on grounds that benefit is conferred, one is faced with a difficult moral dilemma argues the first author, a philosopher. Either one needs to be able to say why human lives of any quality however low should be inviolable from painful experimentation when animal lives are not; or one should accept that sufficient benefit can justify certain painful experiments on human beings of (...)
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  30.  26
    The Law and Ethics of Medical Research: International Bioethics and Human Rights.Aurora Plomer - 2005 - Cavendish.
    This book examines the controversies surrounding biomedical research in the twenty-first century from a human rights perspective, analyzing the evolution and ...
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  31.  1
    The Law and Regulation of Clinical Research: Interplay with Public Policy and Bioethics.Pamela A. Andanda - 2006 - Focus Publilshers.
  32. Metaphysical and Ethical Perspectives on Creating Animal-Human Chimeras.J. T. Eberl & R. A. Ballard - 2009 - Journal of Medicine and Philosophy 34 (5):470-486.
    This paper addresses several questions related to the nature, production, and use of animal-human (a-h) chimeras. At the heart of the issue is whether certain types of a-h chimeras should be brought into existence, and, if they are, how we should treat such creatures. In our current research environment, we recognize a dichotomy between research involving nonhuman animal subjects and research involving human subjects, and the classification of a research protocol into one of these categories will trigger different (...)
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  33.  1
    Ethics in Medicine.Milton D. Heifetz - 1992 - Prometheus Books.
    Ethical questions in medicine have become common topics of discussion during the past twenty years. Bitter disputes have arisen regarding abortion, suicide, human experimentation, as well as the management of the dying patient and the severely disabled newborn. These issues are loaded with such emotion that it is sometimes difficult to look at them in a rational manner. Noted neurosurgeon and author Milton D. Heifetz has made the tough decisions in tragic, often anguishing situations. As a (...)
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  34.  29
    Measurement of Moral Development in Medicine.Donnie J. Self & Evi Davenport - 1996 - Cambridge Quarterly of Healthcare Ethics 5 (2):269.
    The past two decades have been a time of heightened interest in the moral aspects of the practice of medicine. This interest has been reflected in medical education by the establishment of medical humanities programs in both preclinical and clinical education in many medical schools. It has also been reflected in the literature with a dramatic increase in journal articles on medical ethics as well as the development of medical ethics in textbooks. A number of journals have (...)
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  35.  60
    Ethical Aspects of Donor Consent in Transplantation.J. Mahoney - 1975 - Journal of Medical Ethics 1 (2):67-70.
    Two recent events have caused renewed anxiety concerning the ethics of donor transplantation. The first is the report of the British Transplantation Society and the second is the Bill introduced by Mr Tam Dalyell MP (see page 61 of this issue) in which he seeks to establish by law that unless an individual in his life time has expressly contracted out his organs may after death be used for transplantation. Dr Mahoney in this paper therefore examines from the point of (...)
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  36.  12
    Cognitive, Emotive, and Ethical Aspects of Decision Making in Humans and in Ai.Iva Smit, Wendell Wallach & G. E. Lasker (eds.) - 2005 - International Institute for Advanced Studies in Systems Research and Cybernetics.
  37.  20
    Narrative, Ethics, and Human Experimentation in Richard Selzer's "Alexis St. Martin": The Miraculous Wound Re-Examined. [REVIEW]David E. Tanner - 2000 - HEC Forum 12 (2):149-160.
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  38.  1
    Ethics Codes in Medicine: Foundations and Achievements of Codification Since 1947.Ulrich Tröhler, Stella Reiter-Theil & Eckhard Herych (eds.) - 1998 - Ashgate.
    This book contains the results of two European/American preparatory workshops for the First World Conference on Ethics Codes in Medicine and Biotechnology (October 1997, Freiburg, Germany) supported by the leading national institutions in the field. It aims to stimulate research about codes, the effects of codification and other forms of implementing ethics. It breaks new ground with interdisciplinary and international discourse on the subject, emphasising the need for a complete collection of codes for systematic research and evaluation and filling (...)
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  39.  12
    Human Experimentation.C. Susanne - 1997 - Global Bioethics 10 (1-4):123-128.
    Human experimentation can have different meanings: indeed, with the development of medical research, therapeutic acts have to be distinguished from acts of cognitive values. For each kind of acts, specific conditions of acceptability and specific protections of human beings have to be defined.Human experimentation must be envisaged at different levels to evaluate ethical aspects: its scientific value, the risks, benefits envisaged, the populations implicated, etc…The individual consent must be present too in the relationship (...)
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  40.  88
    Moral Community and Animal Research in Medicine.R. G. Frey - 1997 - Ethics and Behavior 7 (2):123 – 136.
    The invocation of moral rights in moral/social debate today is a recipe for deadlock in our consideration of substantive issues. How we treat animals and humans in part should derive from the value of their lives, which is a function of the quality of their lives, which in turn is a function of the richness of their lives. Consistency in argument requires that humans with a low quality of life should be chosen as experimental subjects over animals with (...)
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  41. Ethics, Humans and Other Animals: An Introduction with Readings.Rosalind Hursthouse - 2000 - Routledge.
    This introductory textbook is ideally suited to newcomers to philosophy and ethical problems. Rosalind Hursthouse carefully introduces the three standard approaches in current ethical theory: utilitarianism, rights, and virtue ethics. She links each chapter to readings from key exponents such as Peter Singer and Mary Midgley and asks students to think critically about these readings for themselves. Key features include clear activities and activities, chapter summaries and guides to further reading.
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  42.  12
    Commonsense Morality and the Ethics of Killing in War: An Experimental Survey of the Israeli Population.Yitzhak Benbaji, Amir Falk & Yuval Feldman - 2015 - Law and Ethics of Human Rights 9 (2):195-227.
    Journal Name: The Law & Ethics of Human Rights Issue: Ahead of print.
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  43.  17
    Commonsense Morality and the Ethics of Killing in War: An Experimental Survey of the Israeli Population.Yitzhak Benbaji, Amir Falk & Yuval Feldman - 2015 - The Law and Ethics of Human Rights 9 (2):195-227.
  44.  3
    Ethical Aspects of Dying and Death in Clinical Practice in Anaesthesiology and Intensive Medicine Departments.Marián Bednár & Jozef Firment - 2021 - Human Affairs 31 (1):89-98.
    In clinical practice, modern medicine, especially intensive medicine, has made outstanding technological progress that has changed diagnostic and therapeutic paradigms. Nowadays, some patients for whom there were no treatments in the past not only survive but return to active life thanks to intensive medicine. However, in some cases intensive care will not help patients in a critical condition and merely prolong death. In such situations, the treatment is terminated or not extended, and the patient is allowed to (...)
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  45.  24
    Interventions in the Human Genome: Some Moral and Ethical Considerations.Gerd Richter & Matthew D. Bacchetta - 1998 - Journal of Medicine and Philosophy 23 (3):303 – 317.
    In the debate regarding the different possibilities for gene therapy, it is presupposed that the manipulations are limited to the nuclear genome (nDNA). Given recent advances in genetics, mitochondrial genome (mtDNA) and diseases must be considered as well. In this paper, we propose a three dimensional framework for the ethical debate of gene therapy where we add the genomic type (nDNA vs. mtDNA) as a third dimension to be considered beside the paradigmatic dimensions of target cell (somatic vs. germ-line) (...)
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  46. LET'S FAKE MORALITY and ETHICS (the Pretence of Ethics and Morality in Philosophy and Life).Ulrich De De Balbian - 2017 - Oxford: Academic Publishers.
    Institutionalized and internalized, competence intersubjectivity contain many user-illusions and an imaginary or manifest image of reality, including of themselves (Dennett and Sellars),. This can be contrasted we a comprehension or comprehensive, understanding intersubjectivity. It is possible and perhaps even necessary to transform or replace the competence intersubjectivity to a comprehension or understanding (scientific, Dennett and Sellars) image of reality and themselves.Ethics and morality and studies of ethics and morality deal with the reality of competence intersubjectivity (by means of socio-cultural practices (...)
     
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  47.  1
    Human Experimentation and Medical Ethics: Proceedings of the Xvth Cioms Round Table Conference, Manila, 13-16 September 1981. [REVIEW]Zbigniew Bańkowski & Norman Howard-Jones (eds.) - 1982 - Who Publications Centre Usa [Distributor].
  48.  75
    Epistemology and Ethics of Evidence-Based Medicine: Putting Goal-Setting in the Right Place.Piersante Sestini - 2010 - Journal of Evaluation in Clinical Practice 16 (2):301-305.
    While evidence-based medicine (EBM) is often accused on relying on a paradigm of 'absolute truth', it is in fact highly consistent with Karl Popper's criterion of demarcation through falsification. Even more relevant, the first three steps of the EBM process are closely patterned on Popper's evolutionary approach of objective knowledge: (1) recognition of a problem; (2) generation of solutions; and (3) selection of the best solution. This places the step 1 of the EBM process (building an answerable question) in (...)
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  49. Human Development in Business: Values and Humanistic Management in the Encyclical 'Caritas in Veritate'.Domènec Melé & Claus Dierksmeier (eds.) - 2012 - Palgrave-Macmillan.
    A significant voice in encouraging the theoretical development and practical implementation of humanistic management is Pope Benedict XVI. In his Encyclical Letter Caritas in Veritate, published in 2009, he proposed a new humanistic synthesis to realign the economy with its social purpose. The aim of this book is to interpret, comment, and develop aspects of this Encyclical Letter which are significant for economic and business activity and contribute to humanistic management. The authors, specialists in their different fields, provide an (...)
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  50.  62
    Manual for Research Ethics Committees: Centre of Medical Law and Ethics, King's College London.Sue Eckstein (ed.) - 2003 - Cambridge University Press.
    The sixth edition of the Manual for Research Ethics Committees is a unique compilation of legal and ethical guidance which will prove invaluable for members of research ethics committees, researchers involved in research with humans, members of the pharmaceutical industry and students of law, medicine, ethics and philosophy. Presented in a clear and authoritative form, it incorporates the key legal and ethical guidelines and specially written chapters on major topics in bioethics by leading academic authors and practitioners, (...)
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