Results for 'Hyunmin Cheong'

75 found
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  1. A First-Order Logic Formalization of the Industrial Ontology Foundry Signature Using Basic Formal Ontology.Barry Smith, Farhad Ameri, Hyunmin Cheong, Dimitris Kiritsis, Dusan Sormaz, Chris Will & J. Neil Otte - 2019 - In Barry Smith, Farhad Ameri, Hyunmin Cheong, Dimitris Kiritsis, Dusan Sormaz, Chris Will & J. Neil Otte (eds.), ”, Proceedings of the Joint Ontology Workshops (JOWO), Graz.
    Basic Formal Ontology (BFO) is a top-level ontology used in hundreds of active projects in scientific and other domains. BFO has been selected to serve as top-level ontology in the Industrial Ontologies Foundry (IOF), an initiative to create a suite of ontologies to support digital manufacturing on the part of representatives from a number of branches of the advanced manufacturing industries. We here present a first draft set of axioms and definitions of an IOF upper ontology descending from BFO. The (...)
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  2.  22
    Towards an ontology for generative design of mechanical assemblies.Bahar Aameri, Hyunmin Cheong & J. Christopher Beck - 2019 - Applied ontology 14 (2):127-153.
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  3.  2
    Tweeting Prayers and Communicating Grief Over Michael Jackson Online.Pauline Hope Cheong & Jimmy Sanderson - 2010 - Bulletin of Science, Technology and Society 30 (5):328-340.
    Death and bereavement are human experiences that new media helps facilitate alongside creating new social grief practices that occur online. This study investigated how people’s postings and tweets facilitated the communication of grief after pop music icon Michael Jackson died. Drawing on past grief research, religion, and new media studies, a thematic analysis of 1,046 messages was conducted on three mediated sites (Twitter, TMZ.com, and Facebook). Results suggested that social media served as grieving spaces for people to accept Jackson’s death (...)
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  4.  4
    What Makes Consumers’ Intention to Purchase Paid Stickers in Personal Messenger? The Role of Personality and Motivational Factors.Hyunmin Kang, YounJung Park, Yonghwan Shin, Hobin Choi & Sungtae Kim - 2022 - Frontiers in Psychology 12.
    Many messengers and social networking services use emojis and stickers as a means of communication. Stickers express individual emotions well, allowing long texts to be replaced with small pictures. As the use of stickers increased, stickers were commercialized on a few platforms and showed remarkable growth as people bought and used stickers with their favorite characters, products, or entertainers online. Depending on their personality, individuals have different motivations for using stickers that determine the usefulness and enjoyment of stickers, affecting their (...)
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  5. The Unobserved Heterogeneneous Influence of Gamification and Novelty-Seeking Traits on Consumers’ Repurchase Intention in the Omnichannel Retailing.Cheong Kim, Francis Joseph Costello & Kun Chang Lee - 2020 - Frontiers in Psychology 11.
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  6. A Study on the Development of Abhisekha Ritual. 국광희 & Seongjoon Cheong - 2018 - The Journal of Indian Philosophy 54:93-122.
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  7.  28
    The Analysis of Self-Presentation of Fortune 500 Corporations in Corporate Web Sites.Hyehyun Hong, Hyunmin Lee & Jongmin Park - 2016 - Business and Society 55 (5):706-737.
    In the digital age, many corporations communicate with their publics via online channels. Among many channels, a corporation’s official Web site is often used for informing publics of its performance and other corporate-related information and for shaping a positive corporate image. This study quantitatively analyzed corporate Web sites, particularly the “About us” Web pages of Fortune 500 corporations based on symbolic convergence theory, which describes the formation of symbolic reality and the shared meaning of that symbolic reality among the public. (...)
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  8. To Honor our Heroes: Analysis of the Obituaries of Australians Killed in Action in WWI and WWII.Marc Cheong & Mark Alfano - 2021 - 2020 25th International Conference on Pattern Recognition (ICPR).
    Obituaries represent a prominent way of expressing the human universal of grief. According to philosophers, obituaries are a ritualized way of evaluating both individuals who have passed away and the communities that helped to shape them. The basic idea is that you can tell what it takes to count as a good person of a particular type in a particular community by seeing how persons of that type are described and celebrated in their obituaries. Obituaries of those killed in conflict, (...)
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  9.  19
    Language games and their types.Jonathan Ginzburg & Kwong-Cheong Wong - 2024 - Linguistics and Philosophy 47 (1):149-189.
    One of the success stories of formal semantics is explicating responsive moves like answers to questions. There is, however, a significant lacune concerning the characterization of _initiating utterances_, which are strongly tied to the conversational activity [language game (Wittgenstein), speech genre (Bakhtin)], or—our terminology—_conversational type_, one is engaged in. To date there has been no systematic proposal trying to account for the range of possible _language games_/_speech genres_/_conversational types_ and their global structure. In particular, concerning the range of subject matter (...)
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  10. A tragic coalition of the rational and irrational: a threat to collective responses to COVID-19.Marinus Ferreira, Marc Cheong, Colin Klein & Mark Alfano - 2022 - Philosophical Psychology (6).
    There is not as much resistance to COVID-19 mitigation as there seems, but there are structural features that make resistance seem worse than it is. Here we describe two ways that the problem seeming to be worse than it is can make it worse. First, visible hesitation to implement COVID-19 responses signals to the wider society that mitigation measures may not succeed, which undermines people’s conditional willingness to join in on those efforts. Second, our evaluations of others’ willingness to implement (...)
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  11. Investigating gender and racial biases in DALL-E Mini Images.Marc Cheong, Ehsan Abedin, Marinus Ferreira, Ritsaart Willem Reimann, Shalom Chalson, Pamela Robinson, Joanne Byrne, Leah Ruppanner, Mark Alfano & Colin Klein - forthcoming - Acm Journal on Responsible Computing.
    Generative artificial intelligence systems based on transformers, including both text-generators like GPT-4 and image generators like DALL-E 3, have recently entered the popular consciousness. These tools, while impressive, are liable to reproduce, exacerbate, and reinforce extant human social biases, such as gender and racial biases. In this paper, we systematically review the extent to which DALL-E Mini suffers from this problem. In line with the Model Card published alongside DALL-E Mini by its creators, we find that the images it produces (...)
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  12.  4
    'Twitter Is Dead, Long Live X!' A Decade of Microblog Research and Implications for Knowledge and Research.Marc Cheong - unknown
    Talk at the Philosophy [in:of:for:and] Digital Knowledge Infrastructures online workshop 2023 (28/09/2023).
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  13.  32
    The positive contribution of confucianism to the modernization of east asian business enterprises.Cheong K. Han - 1992 - Journal of Chinese Philosophy 19 (2):171-181.
  14. The use of animals in medical education: A question of necessity vs. desirability.Josepha Cheong - 1989 - Theoretical Medicine and Bioethics 10 (1).
    An issue in current animal welfare ethics is the use of animals in medical education. At stake is the conflict of pain and suffering of the animals vs. the benefit to the students. The educator's role is to balance these two concepts. If the animals do suffer, this has to be justified by clearly establishing the necessity of their use. Neither this justification nor the methods for making the decision are clear. Addressed in this discussion are the arguments for and (...)
     
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  15.  2
    Unpacking gender mainstreaming: a critical discourse analysis of agricultural and rural development policy in Myanmar and Nepal.Dawn D. Cheong, Bettina Bock & Dirk Roep - forthcoming - Agriculture and Human Values:1-15.
    Conventional gender analysis of development policy does not adequately explain the slow progress towards gender equality. Our research analyses the gender discourses embedded in agricultural and rural development policies in Myanmar and Nepal. We find that both countries focus on increasing women’s participation in development activities as a core gender equality policy objective. This creates a binary categorisation of participating versus non-participating women and identifies women as responsible for improving their position. At the same time, gender (in)equality is defined exclusively (...)
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  16.  17
    Understanding E-Commerce Consumers’ Repeat Purchase Intention: The Role of Trust Transfer and the Moderating Effect of Neuroticism.Hyeon Gyu Jeon, Cheong Kim, Jungwoo Lee & Kun Chang Lee - 2021 - Frontiers in Psychology 12.
    The dominant position of e-commerce is especially being articulated in the retailing industry once again due to several constraints that the world faces in the COVID-19 pandemic era. In this regard, this study explores the significant role of trust transfer and the moderating effect of consumers’ neurotic traits in the framework of trust-satisfaction-repurchase intention in the e-commerce context based on a survey with 406 Korean e-commerce consumers. Moreover, a prediction-oriented segmentation technique combined with structural equation models was utilized to reveal (...)
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  17.  17
    Introducing the 21st Century's New Four Horsemen of the Coronapocalypse.Kang Hao Cheong & Michael C. Jones - 2020 - Bioessays 42 (7):2000063.
    As the world struggles through the COVID‐19 pandemic, we should also be asking what systems‐level measures will be needed to prevent this or even worse disasters from happening in the future. We argue that the pandemic is merely one of potentially myriad and pleiomorphic future global disasters generated by the same underlying dynamical system. We explain that there are four broad but easily identifiable systemic, pathologically networked conditions that are hurtling civilization toward potential self‐destruction. As long as these conditions are (...)
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  18.  3
    The influence of visual and vestibular orientation cues in a clock reading task.Nicolas Davidenko, Yeram Cheong, Amanda Waterman, Jacob Smith, Barrett Anderson & Sarah Harmon - 2018 - Consciousness and Cognition 64:196-206.
  19.  12
    A State of Uncertainty: An Analysis of Recent State Legislative Proposals to Regulate Preventive Services in the United States.Maxim Gakh, Cody Cris, Prescott Cheong & Courtney Coughenour - 2019 - Inquiry: The Journal of Health Care Organization, Provision, and Financing 56:004695801984151.
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  20.  22
    Black Swans of CRISPR: Stochasticity and Complexity of Genetic Regulation.Kang Hao Cheong, Jin Ming Koh & Michael C. Jones - 2019 - Bioessays 41 (7):1900032.
    Graphical AbstractRecent waves of controversies surrounding genetic engineering have spilled into popular science in Twitter battles between reputable scientists and their followers. Here, a cautionary perspective on the possible blind spots and risks of CRISPR and related biotechnologies is presented, focusing in particular on the stochastic nature of cellular control processes.
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  21.  14
    Paradoxical Survival: Examining the Parrondo Effect across Biology.Kang Hao Cheong, Jin Ming Koh & Michael C. Jones - 2019 - Bioessays 41 (6):1900027.
    Parrondo's paradox, in which losing strategies can be combined to produce winning outcomes, has received much attention in mathematics and the physical sciences; a plethora of exciting applications has also been found in biology at an astounding pace. In this review paper, the authors examine a large range of recent developments of Parrondo's paradox in biology, across ecology and evolution, genetics, social and behavioral systems, cellular processes, and disease. Intriguing connections between numerous works are identified and analyzed, culminating in an (...)
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  22. The wisdom-of-crowds: an efficient, philosophically-validated, social epistemological network profiling toolkit.Colin Klein, Marc Cheong, Marinus Ferreira, Emily Sullivan & Mark Alfano - 2023 - In Hocine Cherifi, Rosario Nunzio Mantegna, Luis M. Rocha, Chantal Cherifi & Salvatore Miccichè (eds.), Complex Networks and Their Applications XI: Proceedings of The Eleventh International Conference on Complex Networks and Their Applications: COMPLEX NETWORKS 2022 — Volume 1. Springer.
    The epistemic position of an agent often depends on their position in a larger network of other agents who provide them with information. In general, agents are better off if they have diverse and independent sources. Sullivan et al. [19] developed a method for quantitatively characterizing the epistemic position of individuals in a network that takes into account both diversity and independence; and presented a proof-of-concept, closed-source implementation on a small graph derived from Twitter data [19]. This paper reports on (...)
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  23.  15
    Hypocrisy Around Medical Patient Data: Issues of Access for Biomedical Research, Data Quality, Usefulness for the Purpose and Omics Data as Game Changer.Erwin Tantoso, Wing-Cheong Wong, Wei Hong Tay, Joanne Lee, Swati Sinha, Birgit Eisenhaber & Frank Eisenhaber - 2019 - Asian Bioethics Review 11 (2):189-207.
    Whether due to simplicity or hypocrisy, the question of access to patient data for biomedical research is widely seen in the public discourse only from the angle of patient privacy. At the same time, the desire to live and to live without disability is of much higher value to the patients. This goal can only be achieved by extracting research insight from patient data in addition to working on model organisms, something that is well understood by many patients. Yet, most (...)
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  24.  11
    Superposition of COVID‐19 waves, anticipating a sustained wave, and lessons for the future.Joel Weijia Lai & Kang Hao Cheong - 2020 - Bioessays 42 (12):2000178.
    The 2019 coronavirus (COVID‐19), also known as SARS‐CoV‐2, is highly pathogenic and virulent, and it spreads very quickly through human‐to‐human contact. In response to the growing number of cases, governments across the spectrum of affected countries have adopted different strategies in implementing control measures, in a hope to reduce the number of new cases. However, 5 months after the first confirmed case, countries like the United States of America (US) seems to be heading towards a trajectory that indicates a health (...)
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  25.  10
    An Empirical Approach to Analyzing the Effects of Stress on Individual Creativity in Business Problem-Solving: Emphasis on the Electrocardiogram, Electroencephalogram Methodology.Jungwoo Lee, Cheong Kim & Kun Chang Lee - 2022 - Frontiers in Psychology 13.
    In this study, experiments were conducted on 30 subjects by means of electrocardiogram and electroencephalogram methodologies as well as a money game to examine the effects of stress on creativity in business problem-solving. The study explained the relationship between creativity and human physiological response using the biopsychosocial model of challenge and threat. The subjects were asked to perform a cognitive mapping task. Based on the brain wave theory, we identified the types of brain waves and locations of brain activities that (...)
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  26.  3
    Evaluating Global Inequality Using Decomposition Approach.Ning Ma, Tsun Se Cheong & Jing Li - 2022 - Frontiers in Psychology 12:809670.
    Given that there is no recent research on decomposition for global inequality, the aim of this study is to fill the gap in the literature by investigating global inequality with decomposition technique. The data of this study were compiled from the World Bank and decomposition by subgroups was conducted to evaluate the driving forces behind the evolution of inequality. Almost all the countries in the world were included in this study, and the study period spans from 2000 to 2017. The (...)
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  27.  32
    Existentialism on Social Media: The ‘Look’ of the ‘Crowd’.Marc Cheong - 2023 - Journal of Human-Technology Relations 1.
    Social media has become a basis for helping us maintain human contact, especially as our alienation from our phenomenological experiences of ‘being human’ is becoming apparent due to the pandemic. I argue for how existentialist philosophy is crucial, more than ever, to interrogate our social media usage, which is a ‘necessary evil’ in our daily lives. Firstly, Kierkegaard’s critiques of the crowd and of the press are equally applicable to social media, which plays both roles: enabling an anonymous mass of (...)
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  28. Ethical Dilemmas for @Celebrities: Promoting #Intimacy, Facing #Inauthenticity, and Defusing #Invectiveness.Marc Cheong - 2022 - Ethical Perspectives 29 (1):139-166.
    The rise of social-media-mediated celebrity culture raises several philosophical concerns. Therefore, it is not uncommon to see, for example, Hollywood actors being placed in the same bracket as YouTube artists and Instagram influencers. The increased perceived ‘connectivity’ afforded by social media allows online celebrities to reach more fans and increases the perceived engagement or intimacy in the fan-celebrity relationship. In this paper I argue that this online relationship, which is beneficial to celebrities (for brand development) and social media companies (in (...)
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  29.  25
    Pedestrian Group-Crossing Behavior Modeling and Simulation Based on Multidimensional Dirty Faces Game.Shunqiang Ye, Lu Wang, Kang Hao Cheong & Nenggang Xie - 2017 - Complexity:1-12.
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  30. Experimental investigations of #authenticity online.Marc Cheong - manuscript
    The concept of 'authenticity' is highly valued on social media sites (SMSes), despite its ambiguous nature and definition. One interpretation of 'authenticity' by media scholars is a human's congruence with online portrayals of themselves (e.g. posting spontaneous photographs from their lives, or using real biodata online). For marketers and 'influencers', these patterns of behaviour can achieve certain gains: sales for a business, or success of a campaign. For existentialist philosophers, using 'authenticity' as a means to an end is against its (...)
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  31. Asymmetry in Online Social Networks.Marc Cheong - manuscript
    Varying degrees of symmetry can exist in a social network's connections. Some early online social networks (OSNs) were predicated on symmetrical connections, such as Facebook 'friendships' where both actors in a 'friendship' have an equal and reciprocal connection. Newer platforms -- Twitter, Instagram, and Facebook's 'Pages' inclusive -- are counterexamples of this, where 'following' another actor (friend, celebrity, business) does not guarantee a reciprocal exchange from the other. -/- This paper argues that the basic asymmetric connections in an OSN leads (...)
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  32.  21
    Long-term evolution of business ethics in Hong Kong.Tsun Se Cheong, Felix Tang, Andy Cheng, Michal Wojewodzki & Sunny Chan - 2023 - International Journal of Business Governance and Ethics 1 (1):1.
  33.  53
    Guest Editors' Introduction: Examining Moral Emotions in Nietzsche with the Semantic Web Exploration Tool: Nietzsche.Mark Alfano & Marc Cheong - 2019 - Journal of Nietzsche Studies 50 (1):1-10.
    Five years ago, the Journal of Nietzsche Studies published a special issue on Nietzsche and the affects. In it, Aurelia Armstrong wrote generically about the passions, Michael Ure discussed Schadenfreude, Joanne Faulkner addressed disgust, and Joseph Kuzma focused on eroticism.1 In subsequent issues, authors have discussed love,2 emotion in general,3 resentment,4 compassion,5 honor and empathy,6 and affect in general.7 This special section on emotions and reactive attitudes is a chance to take stock of the progress we have made as a (...)
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  34.  3
    A Study on the Formation of Tilaka in the History of Buddhist Tantrism.Seongjoon Cheong - 2007 - The Journal of Indian Philosophy 22 (null):29-56.
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  35. A Tale of Two Anti-Heroes.Marc Cheong - 2022 - In Christian Cotton & Andrew M. Winters (eds.), Neon Genesis Evangelion and Philosophy. Chicago: Open Universe.
    This book chapter in Neon Genesis Evangelion and Philosophy (Open Universe) draws parallels between the main anti-heroes in Albert Camus's The Stranger and Neon Genesis Evangelion, and introduces common existential concepts such as facticity/transcendence and bad faith, aimed at a general readership.
     
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  36.  1
    Development of Buddhist Tantrism Concern about Life and Death.Seongjoon Cheong - 2013 - The Journal of Indian Philosophy 37:141-164.
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  37.  3
    Globalization and Migratory Processes in the Socio-reli-gious, Economic and Political Context of the Malay Muslims of Malaysia.John Cheong - 2008 - Transformation: An International Journal of Holistic Mission Studies 25 (4):217-233.
    Globalization in Malaysia has introduced the Malay Muslim population to new ethno- religious dynamics at the urban-to-urban level internationally and rural-to-urban sphere nationally. At the international level, Malay Muslims who studied abroad have returned with alternate conceptions of Islam at odds with the local version as well as fostered transnational links to outsiders that later facilitated their religious influence locally. At the national level, Malay Muslim migration to an urban economy opened to global capitalism have produced reactionary discourses and attitudes (...)
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  38.  8
    Is Possible the Model of Cultivation of Mind in Curriculum?Hye-Jin Cheong - 2007 - Journal of Moral Education 18 (2):171.
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  39.  4
    Marriage Transmitted Debt in the Chinese Civil Code: The Beginning of a Solution Rather than the End.May Fong Cheong & Jie Huang - 2021 - Feminist Legal Studies 30 (1):1-27.
    This paper is the first to critically analyse how the newly enacted Chinese Civil Code addresses gender equality in the intersection of family and commercial contracting. It proposes ‘marriage transmitted debt’ (MTD) in China as a new concept as opposed to ‘sexually transmitted debt’ (STD) documented in English and Australian jurisprudence. MTD refers to the debt incurred by one spouse but transmitted to the other spouse due to the status of the marriage. Supported by empirical statistics, it shows that while (...)
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  40.  19
    Religion and Education in Froebel's Theory of Education : The Moral Educational Implication.Hye-Jin Cheong - 2005 - Journal of Moral Education 16 (2):151.
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  41.  6
    Repurposing Vaccines in the Fight against COVID‐19.Kang Hao Cheong - 2020 - Bioessays 42 (11):2000234.
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  42.  4
    Segmentation of Rhythmic Units in Word Speech by Japanese Infants and Toddlers.Yeonju Cheong & Izumi Uehara - 2021 - Frontiers in Psychology 12.
    When infants and toddlers are confronted with sequences of sounds, they are required to segment the sounds into meaningful units to achieve sufficient understanding. Rhythm has been regarded as a crucial cue for segmentation of speech sounds. Although previous intermodal methods indicated that infants and toddlers could detect differences in speech sounds based on stress-timed and syllable-timed units, these methods could not clearly indicate how infants and toddlers perform sound segmentation. Thus, the present study examined whether Japanese infants and toddlers (...)
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  43.  10
    Smart campus communication, Internet of Things, and data governance: Understanding student tensions and imaginaries.Pratik Nyaupane & Pauline Hope Cheong - 2022 - Big Data and Society 9 (1).
    In recent years, universities have been urged to restructure and re-evaluate their ability to trace and monitor their students as the “smart campus” is being built upon datafication, while networked apps and sensors serve as the means through which its constituents are connected and governed. This paper advances a dialectical and communication-centered approach to the Internet of Things campus ecosystem and provides an empirical investigation into the tensions experienced by students and the ways that these students envision alternative practices that (...)
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  44.  5
    Primary School Teachers’ Conceptions of Reading Comprehension Processes and Its Formulation.Xinhua Zhu, Choo Mui Cheong, Guan Ying Li & Jacqueline Wu - 2020 - Frontiers in Psychology 11.
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  45.  4
    Consumer Decision-Making Creativity and Its Relation to Exploitation–Exploration Activities: Eye-Tracking Approach.Eunyoung Choi, Cheong Kim & Kun Chang Lee - 2021 - Frontiers in Psychology 11.
    Modern consumers face a dramatic rise in web-based technological advancements and have trouble making rational and proper decisions when they shop online. When they try to make decisions about products and services, they also feel pressured against time when sorting among all of the unnecessary items in the flood of information available on the web. In this sense, they need to use consumer decision-making creativity to make rational decisions. However, unexplored research questions on this subject remain. First, in what ways (...)
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  46. Technological Seduction and Self-Radicalization.Mark Alfano, Joseph Adam Carter & Marc Cheong - 2018 - Journal of the American Philosophical Association (3):298-322.
    Many scholars agree that the Internet plays a pivotal role in self-radicalization, which can lead to behaviours ranging from lone-wolf terrorism to participation in white nationalist rallies to mundane bigotry and voting for extremist candidates. However, the mechanisms by which the Internet facilitates self-radicalization are disputed; some fault the individuals who end up self-radicalized, while others lay the blame on the technology itself. In this paper, we explore the role played by technological design decisions in online self-radicalization in its myriad (...)
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  47. The Affiliative Use of Emoji and Hashtags in the Black Lives Matter Movement in Twitter.Mark Alfano, Ritsaart Reimann, Ignacio Quintana, Marc Cheong & Colin Klein - 2022 - Social Science Computer Review (N/A).
    Protests and counter-protests seek to draw and direct attention and concern with confronting images and slogans. In recent years, as protests and counter-protests have partially migrated to the digital space, such images and slogans have also gone online. Two main ways in which these images and slogans are translated to the online space is through the use of emoji and hashtags. Despite sustained academic interest in online protests, hashtag activism and the use of emoji across social media platforms, little is (...)
     
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  48.  14
    Evaluating assessment tools of the quality of clinical ethics consultations: a systematic scoping review from 1992 to 2019.Nicholas Yue Shuen Yoon, Yun Ting Ong, Hong Wei Yap, Kuang Teck Tay, Elijah Gin Lim, Clarissa Wei Shuen Cheong, Wei Qiang Lim, Annelissa Mien Chew Chin, Ying Pin Toh, Min Chiam, Stephen Mason & Lalit Kumar Radha Krishna - 2020 - BMC Medical Ethics 21 (1):1-11.
    BackgroundAmidst expanding roles in education and policy making, questions have been raised about the ability of Clinical Ethics Committees (CEC) s to carry out effective ethics consultations (CECons). However recent reviews of CECs suggest that there is no uniformity to CECons and no effective means of assessing the quality of CECons. To address this gap a systematic scoping review of prevailing tools used to assess CECons was performed to foreground and guide the design of a tool to evaluate the quality (...)
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  49.  14
    Condensation of gold vapour on silicone oil – effect of the liquid substrate.P. Anantha, Ting Cheng & Chee Cheong Wong - 2014 - Philosophical Magazine 94 (17):1967-1981.
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  50.  10
    Synaptic Pruning in Schizophrenia: Does Minocycline Modulate Psychosocial Brain Development?Michael C. Jones, Jin Ming Koh & Kang Hao Cheong - 2020 - Bioessays 42 (9):2000046.
    Recent studies suggest that the tetracycline antibiotic minocycline, or its cousins, hold therapeutic potential for affective and psychotic disorders. This is proposed on the basis of a direct effect on microglia‐mediated frontocortical synaptic pruning (FSP) during adolescence, perhaps in genetically susceptible individuals harboring risk alleles in the complement component cascade that is involved in this normal process of CNS circuit refinement. In reviewing this field, it is argued that minocycline is actually probing and modulating a deeply evolved and intricate system (...)
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