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Ineke Bolt [13]Ineke L. L. E. Bolt [2]Ineke L. E. Bolt [1]
  1.  89
    The future of psychopharmacological enhancements: Expectations and policies.Maartje Schermer, Ineke Bolt, Reinoud de Jongh & Berend Olivier - 2009 - Neuroethics 2 (2):75-87.
    The hopes and fears expressed in the debate on human enhancement are not always based on a realistic assessment of the expected possibilities. Discussions about extreme scenarios may at times obscure the ethical and policy issues that are relevant today. This paper aims to contribute to an adequate and ethically sound societal response to actual current developments. After a brief outline of the ethical debate concerning neuro-enhancement, it describes the current state of the art in psychopharmacological science and current uses (...)
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  2.  38
    Recent insights into decision-making and their implications for informed consent.Irene M. L. Vos, Maartje H. N. Schermer & Ineke L. L. E. Bolt - 2018 - Journal of Medical Ethics 44 (11):734-738.
    Research from behavioural sciences shows that people reach decisions in a much less rational and well-considered way than was often assumed. The doctrine of informed consent, which is an important ethical principle and legal requirement in medical practice, is being challenged by these insights into decision-making and real-world choice behaviour. This article discusses the implications of recent insights of research on decision-making behaviour for the informed consent doctrine. It concludes that there is a significant tension between the often non-rational choice (...)
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  3.  16
    The ethics of ethics conferences: Is Qatar a desirable location for a bioethics conference?Rieke van der Graaf, Karin Jongsma, Suzanne van de Vathorst, Martine de Vries & Ineke Bolt - 2023 - Bioethics 37 (4):319-322.
    The next World Congress of Bioethics will be held in Doha, Qatar. Although this location provides opportunities to interact with a more culturally diverse audience, to advance dialogue between cultures and religions, offer opportunities for mutual learning, there are also huge moral concerns. Qatar is known for violations of human rights ‐ including the treatment of migrant workers and the rights of women ‐ corruption, criminalization of LGBTQI+ persons, and climate impact. Since these concerns are also key (bio)ethical concern we (...)
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  4. Botox for the Brain: Enhancement of Cognition, Mood and pro-Social Behavior and Blunting of Unwanted Memories.Reinoud de Jongh, Ineke Bolt, Maartje Schermer & Berend Olivier - 2008 - Neuroscience and Biobehavioral Reviews 32 (4):760–776.
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  5. Psychopharmaceutical enhancers: Enhancing identity?Ineke Bolt & Maartje Schermer - 2009 - Neuroethics 2 (2):103-111.
    The use of psychopharmaceuticals to enhance human mental functioning such as cognition and mood has raised a debate on questions regarding identity and authenticity. While some hold that psychopharmaceutical substances can help users to ‘become who they really are’ and thus strengthen their identity and authenticity, others believe that the substances will lead to inauthenticity, normalization, and socially-enforced adaptation of behaviour and personality. In light of this debate, we studied how persons who actually have experience with the use of psychopharmaceutical (...)
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  6. Wish-fulfilling medicine in practice: a qualitative study of physician arguments.Eva C. A. Asscher, Ineke Bolt & Maartje Schermer - 2012 - Journal of Medical Ethics 38 (6):327-331.
    There has been a move in medicine towards patient-centred care, leading to more demands from patients for particular therapies and treatments, and for wish-fulfilling medicine: the use of medical services according to the patient's wishes to enhance their subjective functioning, appearance or health. In contrast to conventional medicine, this use of medical services is not needed from a medical point of view. Boundaries in wish-fulfilling medicine are partly set by a physician's decision to fulfil or decline a patient's wish in (...)
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  7.  10
    Prevention in the age of personal responsibility: epigenetic risk-predictive screening for female cancers as a case study.Ineke Bolt, Eline M. Bunnik, Krista Tromp, Nora Pashayan, Martin Widschwendter & Inez de Beaufort - 2021 - Journal of Medical Ethics 47 (12):e46-e46.
    Epigenetic markers could potentially be used for risk assessment in risk-stratified population-based cancer screening programmes. Whereas current screening programmes generally aim to detect existing cancer, epigenetic markers could be used to provide risk estimates for not-yet-existing cancers. Epigenetic risk-predictive tests may thus allow for new opportunities for risk assessment for developing cancer in the future. Since epigenetic changes are presumed to be modifiable, preventive measures, such as lifestyle modification, could be used to reduce the risk of cancer. Moreover, epigenetic markers (...)
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  8.  44
    The Controversy Over Pediatric Bariatric Surgery: An Explorative Study on Attitudes and Normative Beliefs of Specialists, Parents, and Adolescents With Obesity.Stefan M. van Geelen, Ineke L. E. Bolt, Olga H. van der Baan-Slootweg & Marieke J. H. van Summeren - 2013 - Journal of Bioethical Inquiry 10 (2):227-237.
    Despite the reported limited success of conventional treatments and growing evidence of the effectiveness of adult bariatric surgery, weight loss operations for (morbidly) obese children and adolescents are still considered to be controversial by health care professionals and lay people alike. This paper describes an explorative, qualitative study involving obesity specialists, morbidly obese adolescents, and parents and identifies attitudes and normative beliefs regarding pediatric bariatric surgery. Views on the etiology of obesity—whether it should be considered primarily a medical condition or (...)
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  9.  5
    Uncertain futures and unsolicited findings in pediatric genomic sequencing: guidelines for return of results in cases of developmental delay.Candice Cornelis, Wybo Dondorp, Ineke Bolt, Guido de Wert, Marieke van Summeren, Eva Brilstra, Nine Knoers & Annelien L. Bredenoord - 2023 - BMC Medical Ethics 24 (1):1-10.
    Background Massively parallel sequencing techniques, such as whole exome sequencing (WES) and whole genome sequencing (WGS), may reveal unsolicited findings (UFs) unrelated to the diagnostic aim. Such techniques are frequently used for diagnostic purposes in pediatric cases of developmental delay (DD). Yet policy guidelines for informed consent and return of UFs are not well equipped to address specific moral challenges that may arise in these children’s situations. Discussion In previous empirical studies conducted by our research group, we found that it (...)
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  10.  15
    Informed Decision-Making and Capabilities in Population-based Cancer Screening.Ineke L. L. E. Bolt, Maartje H. N. Schermer, Hanna Bomhof-Roordink & Danielle R. M. Timmermans - 2022 - Public Health Ethics 15 (3):289-300.
    Informed decision-making (IDM) is considered an important ethical and legal requirement for population-based screening. Governments offering such screening have a duty to enable invitees to make informed decisions regarding participation. Various views exist on how to define and measure IDM in different screening programmes. In this paper we first address the question which components should be part of IDM in the context of cancer screening. Departing from two diverging interpretations of the value of autonomy—as a right and as an ideal—we (...)
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  11. Soorten van gelijk. Medisch-ethische discussies in Nederland.Ineke Bolt, Suzanne Vathorst & M. Trappenburg - 1996 - Filosofie En Praktijk 15:209-209.
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  12.  20
    Contextualizing Genetic Testing and Sequencing Results for Patients and Parents: The Need for Empirical-Ethical Research.Candice Cornelis, Ineke Bolt & Marieke Van Summeren - 2014 - American Journal of Bioethics 14 (3):10-12.
  13. and the Gray Area between Treatment and Enhancement.Maartje Schermer & Ineke Bolt - 2011 - In Julian Savulescu, Ruud ter Meulen & Guy Kahane (eds.), Enhancing Human Capacities. Blackwell. pp. 179.
     
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  14.  30
    Introduction.Maartje Schermer & Ineke Bolt - 2009 - Neuroethics 2 (2):61-62.
    The use of psychopharmaceuticals to enhance human mental functioning such as cognition and mood has raised a debate on questions regarding identity and authenticity. While some hold that psychopharmaceutical substances can help users to ‘become who they really are’ and thus strengthen their identity and authenticity, others believe that the substances will lead to inauthenticity, normalization, and socially-enforced adaptation of behaviour and personality. In light of this debate, we studied how persons who actually have experience with the use of psychopharmaceutical (...)
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  15.  8
    What's in a Name? ADHD and the Gray Area between Treatment and Enhancement.Maartje Schermer & Ineke Bolt - 2011 - In Julian Savulescu, Ruud ter Meulen & Guy Kahane (eds.), Enhancing Human Capacities. Blackwell. pp. 179–193.
    In a discussion about human enhancement it is common to make a distinction between medical treatment and enhancement. The treatment‐enhancement (TE) distinction may work as long as we are faced with extreme and evident examples of treatments and enhancements, but it leaves us with unanswered questions if we are confronted with the borderlines cases in the muddy gray area between obvious treatment and obvious enhancement. This chapter focuses on this gray area, shows its complexities, and asks how we can answer (...)
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  16.  59
    Tailor-made pharmacotherapy: Future developments and ethical challenges in the field of pharmacogenomics.Johannes Van Delden, Ineke Bolt, Annemarie Kalis, Jeroen Derijks & Hubert Leufkens - 2004 - Bioethics 18 (4):303–321.
    In this article ethical issues are discussed which play a role in pharmacogenetics. Developments in pharmacogenetics have a large impact on many different practices such as clinical trials, the practice of medicine and society at large. In clinical trials, questions rise regarding the exclusion of genetic subgroups that may be non- or poor-responders to the experimental drug. Also, the question is asked how pharmaceutical companies should deal with their growing knowledge about the relations between genetic variation and adverse effects. Moreover, (...)
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