There is a growing consensus that results generated through multiplex genetic tests, even those produced as a part of research, should be reported to providers and patients when they are considered “actionable,” that is, when they could be used to inform some potentially beneficial clinical action. However, there remains controversy over the precise criterion that should be used in identifying when a result meets this standard. In this paper, we seek to refine the concept of “actionability” by exploring one proposed (...) use for genetic test results. We argue that genetic test results indicating that a patient is at risk for developing a chronic health condition should not be considered actionable if the only potential value of that result is to motivate patients to make changes in their health behaviors. Since the empirical research currently available on this question is equivocal, we explore relevant psychological theories of human motivation to demonstrate that current theory does not support the assumption that information about genetic risk will be motivating to most patients in their attempts to make changes in health behaviors. (shrink)

The state, by V.I. Lenin.--The revolutionary part played by law and the state; a general doctrine of law, by P.I. Stuchka.--The theory of Petrazhitskii: Marxism and social ideology. Law, our law, foreign law, general law, by M.A. Reisner.--The general theory of law and Marxism, by E.B. Pashukanis.--The right deviation in the Communist Party of Bolsheviks. Political report of the Central (Party) Committee to the XVI Congress, 1930, by J.V. Stalin.-- The Soviet state and the revolution in law, by E.B. Pashukanis.--Socialism (...) and law, by P. Yudin.--The fundamental tasks of the science of Soviet socialist law, by A.Y. Vyshinsky.--Report to the XVIII Party Congress, by J.V. Stalin.--The theory of the state and law, by S.A. Golunskii and M.S. Strogovich.--The Soviet state in the war for the fatherland, by A.Y. Vyshinsky.--The relationship between state and law, by I.P. Trainin. (shrink)

In the paper I offer a brief sketch of one of the sources of utilitarianism. Our biological ancestry is a matter of fact that is not altered by the way we describe ourselves. With philosophical theories it is otherwise. Utilitarianism can be described in ways that make it look as if it is as old as moral philosophy – as J. S. Mill thought it was. For my historical purposes, it is more useful to have an account that brings out (...) what is specific about Benthamism and its descendants. Let us try to make do with the following. First, utilitarianism asserts that the fundamental requirement of morality is that we are to maximize good, for everyone and not just for the agent. This basic principle presupposes that it makes sense to think of aggregating goods to make a total, and of comparing amounts of good thus aggregated. Second, the good to be brought about is located in feelings of pleasure, and the evil to be avoided in feelings of pain. These feelings have inherent value or disvalue regardless of how they are caused to exist and regardless of their own consequences. Third, all moral principles can be derived from the requirement that good be maximized. The principles involved in evaluating agents as well as in giving moral direction to action are nothing but applications of the basic principle. (shrink)

J. B. Schneewind's "The Invention of Autonomy" has been hailed as a major interpretation of modern moral thought. Schneewind's narrative, however, elides several serious interpretive issues, particularly in the transition from late medieval to early modern thought. This results in potentially distorted accounts of Thomas Aquinas, Hugo Grotius, and G. W. Leibniz. Since these thinkers play a crucial role in Schneewind's argument, uncertainty over their work calls into question at least some of Schneewind's larger agenda for the history of ethics.

This is an extremely well-edited collection of articles dealing with Austin. A number of articles help to present general biographical information and to provide an overview of the man and his philosophic style. Three sections of this anthology are divided so as to include papers that deal with issues raised in Austin's Philosophical Papers, Sense and Sensibilia, and How to Do Thing with Words. Papers are included by those who are sympathetic and admire Austin's work as well as those who (...) have been very critical of his work. Altogether this symposium includes a judicious selection of some of the best articles dealing with Austin. There are papers by Warnock, Urmson, Hampshire, Pears, Cavell, Quine, Chisholm, Ayer, Searle, etc. There is a bibliography of Austin's writings as well as writings about Austin.--R. J. B. (shrink)

Reasoning under uncertainty, that is, making judgements with only partial knowledge, is a major theme in artificial intelligence. Professor Paris provides here an introduction to the mathematical foundations of the subject. It is suited for readers with some knowledge of undergraduate mathematics but is otherwise self-contained, collecting together the key results on the subject, and formalising within a unified framework the main contemporary approaches and assumptions. The author has concentrated on giving clear mathematical formulations, analyses, justifications and consequences of the (...) main theories about uncertain reasoning, so the book can serve as a textbook for beginners or as a starting point for further basic research into the subject. It will be welcomed by graduate students and research workers in logic, philosophy, and computer science as a textbook for beginners, a starting point for further basic research into the subject, and not least, an account of how mathematics and artificial intelligence can complement and enrich each other. (shrink)

Among young liberal Catholic intellectuals, Lonergan is held in extremely high esteem. His philosophic treatise, Insight, is considered to be the important philosophic book where Thomism genuinely encounters contemporary secular philosophy. But outside this circle of Catholic intellectuals Lonergan's thought is barely known. This collection of articles does reflect the comprehensiveness and depth of his thought. Papers range over intricate theological discussions of the Assumption, Christ, marriage, the role of a Catholic university in the modern world, and technical philosophic issues (...) such as the form of inference and geometric possibility. Because the papers are short and have been written for a variety of audiences, it is difficult to discern any overreaching continuity and perspective. Many of the discussions demand a more thorough and critical analysis than is exhibited here. The introduction by Crowe is helpful for reconstructing Lonergan's intellectual development and supplying a broader context for appreciating the papers, although the tone is more reverential than critical.—R. J. B. (shrink)

The Philosophy of Chrysippus is a reconstruction of the philosophy of an eminent Stoic philosopher, based upon the fragmentary remains of his voluminous writings. Chrysippus of Cilicia, who lived in a period that covers roughly the last three-quarters of the third century B.C., studied philosophy in Athens and upon Cleanthes’ death became the third head of the Stoa, one of the four great schools of philosophy of the Hellenistic period. Chrysippus wrote a number of treatises in each of the major (...) departments of philosophy, logic, physics, and ethics. Much of his fame derived from his acuteness as a logician, but his importance for Stoic philosophy generally was acknowledged in antiquity in the saying, “Had there been no Chrysippus, there would be no Stoa.” Previous accounts of Chrysippus’ philosophy, including Émile Bréhier’s study, the only work in this century which had sought to deal with Chrysippus’ philosophy alone, blurred the distinctive contributions of Chrysippus to Stoic philosophy and failed to bring to light the peculiar features in his thought. The vagueness in these accounts resulted in large measure from the assumption that if an ancient author ascribed a doctrine to “the Stoics” or “Stoicism”, one could infer that the doctrine belonged to Chrysippus. Professor Gould works from the more circumspect methodological principle that unless an ancient author explicitly ascribes a doctrine to Chrysippus, his testimony cannot be used in reconstructing Chrysippus’ philosophy. Working with those of the fragments in Hans von Arnim’s collection, Stoicorum Veterum Fragmenta, which are explicitly Chrysippean in the sense suggested, Mr. Gould has worked out an account of Chrysippus’ views in the fields of logic, natural philosophy, and ethics. In order that Chrysippus’ thought might be viewed in context Mr. Gould provides a background picture by describing the third century milieu in which the Stoic philosopher worked. This follows an account of Chrysippus’ life and reputation in antiquity and a description of modern assessments of Chrysippus’ position in the Stoa. In his account of Chrysippus’ philosophy Mr. Gould frequently introduces comparisons and contrasts with Plato and Aristotle to help emphasize the continuity between Hellenic and early Hellenistic philosophy. Finally, in a concluding chapter, the author shows that the dominant themes in Chrysippus’ philosophy, while not exhibiting a thoroughly well-knit system, nevertheless are woven together into a remarkably comprehensive whole, which must have been extraordinarily impressive in antiquity. (shrink)