34 found
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  1.  9
    Molecular Biology in the French Tradition? Redefining Local Traditions and Disciplinary Patterns.Jean-Paul Gaudillière - 1993 - Journal of the History of Biology 26 (3):473 - 498.
    The first part of this paper has shown that the development of regulatory genetics and the lactose operon model stemmed from laboratory cultures rooted in local traditions. A "physiological" culture may be recognized in the Pasteurian context. The institutional continuity provided the basis for a tenuous link between Pasteur, Lwoff, and Monod. My claim is that the "national" value of regulatory and physiological genetics is an artifact produced in the course of the legitimization process accompanying the institutionalisation of the discipline. (...)
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  2.  32
    The Tools of the Discipline: Biochemists and Molecular Biologists. [REVIEW]Soraya De Chadarevian & Jean-Paul Gaudillière - 1996 - Journal of the History of Biology 29 (3):327-330.
  3.  7
    Molecular Biologists, Biochemists, and Messenger RNA: The Birth of a Scientific Network. [REVIEW]Jean-Paul Gaudillière - 1996 - Journal of the History of Biology 29 (3):417 - 445.
    This paper investigated the part played by collaborative practices in chaneling the work of prominent biochemists into the development of molecular biology. The RNA collaborative network that emerged in the 1960s in France encompassed a continuum of activities that linked laboratories to policy-making centers. New institutional frameworks such as the DGRST committees were instrumental in establishing new patterns of funding, and in offering arenas for multidisciplinary debates and boundary assessment. It should be stressed however, that although this collaborative network was (...)
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  4.  31
    Genesis and Development of a Biomedical Object: Styles of Thought, Styles of Work and the History of the Sex Steroids.Jean-Paul Gaudillière - 2004 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 35 (3):525-543.
    Many decades after the publication of Genesis and development of a scientific fact, Fleck’s collective Denkstil remains a very important notion for analyzing the history of the biological and medical sciences. Following Fleck’s perspective this paper argues that the history of the sex hormones was critically shaped by our representation of the sexes, and our perceptions of the division of reproductive labor. Emerging at the boundary between physiological laboratories and consultation room, a molecular/endocrine style of thought stabilized during the early (...)
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  5.  11
    Normal Pathways: Controlling Isotopes and Building Biomedical Research in Postwar France. [REVIEW]Jean-Paul Gaudillière - 2006 - Journal of the History of Biology 39 (4):737 - 764.
    During the late 1940s and 1950s, radioisotopes became important resources for biological and medical research. This article explores the strategies used by French researchers to get access to this material, either from the local Atomic Energy Commission (CEA) or from suppliers in the United States or United Kingdom. It focuses on two aspects of this process: the transatlantic circulation of both isotopes and associated instrumentation; the regulation of use and access by the administrative bodies governing research in France. Analyzing the (...)
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  6.  6
    New Wine in Old Bottles? The Biotechnology Problem in the History of Molecular Biology.Jean-Paul Gaudillière - 2009 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 40 (1):20-28.
  7.  54
    New Wine in Old Bottles? The Biotechnology Problem in the History of Molecular Biology.Jean-Paul Gaudillière - 2009 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 40 (1):20-28.
    This paper examines the “biotechnology problem” in the history of molecular biology, namely the alleged reinvention of a basic academic discipline looking for the logic of life, into a typical technoscientific enterprise, closely related to agriculture, medicine, and the construction of markets. The dominant STS model sees the roots of this shift in a radical change of the regime of knowledge production. The paper argues that this scheme needs to be historicized to take into account the past in our biotech (...)
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  8.  4
    Genesis and Development of a Biomedical Object: Styles of Thought, Styles of Work and the History of the Sex Steroids.Jean-Paul Gaudillière - 2004 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 35 (3):525-543.
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  9.  36
    Better Prepared Than Synthesized: Adolf Butenandt, Schering Ag and the Transformation of Sex Steroids Into Drugs (1930–1946). [REVIEW]Jean-Paul Gaudillière - 2005 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 36 (4):612-644.
    This paper follows the trajectory of sex steroids in 1930s Germany as a way to investigate the system of research which characterized the development of these drugs. Analyzing the changing relationship between the pharmaceutical company Schering and the Kaiser Wilhelm Institute für Biochemie headed by Nobel Prize winner Adolf Butenandt, the paper highlights the circulation of materials, information and money as much as the role of patents in shaping the study of sex steroids. Semi-synthetic analogs and metabolic pathways thus emerged (...)
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  10.  5
    The Farm and the Clinic: An Inquiry Into the Making of Our Biotechnological Modernity.Jean-Paul Gaudillière - 2007 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 38 (2):521-529.
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  11.  18
    Le cancer entre infection et hérédité: gènes, virus et souris au National Cancer Institute (1937-1977).Jean Paul Gaudilliere - 1994 - Revue d'Histoire des Sciences 47 (1):57-90.
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  12.  22
    Rockefeller Strategies for Scientific Medicine: Molecular Machines, Viruses and Vaccines.Jean-Paul Gaudillière - 2000 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 31 (3):491-509.
  13.  26
    Introduction: Drug Trajectories.Jean-Paul Gaudillière - 2005 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 36 (4):603-611.
  14.  11
    Introduction: Drug Trajectories.Jean-Paul Gaudillière - 2005 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 36 (4):603-611.
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  15.  12
    The Farm and the Clinic: An Inquiry Into the Making of Our Biotechnological Modernity.Jean-Paul Gaudillière - 2007 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 38 (2):521-529.
  16.  4
    Better Prepared Than Synthesized: Adolf Butenandt, Schering Ag and the Transformation of Sex Steroids Into Drugs.Jean-Paul Gaudillière - 2005 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 36 (4):612-644.
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  17.  3
    Reframing Pathological Heredity: Pedigrees, Molecules, and Genetic Counseling in Postwar France.Jean-Paul Gaudillière - 2011 - Alter - European Journal of Disability Research / Revue Européenne de Recherche Sur le Handicap 5 (1):7-15.
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  18.  33
    The Pharmaceutical Industry in the Biotech Century: Toward a History of Science, Technology and Business?Jean-Paul Gaudillière - 2001 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 32 (1):191-201.
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  19.  24
    Paris–New York Roundtrip: Transatlantic Crossings and the Reconstruction of the Biological Sciences in Post-War France.Jean-Paul Gaudillière - 2002 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 33 (3):389-417.
    During the first years of the post-war era, many French scientists travelled in the United States. As they looked for a reference to be used in rebuilding their own scientific landscape, their diaries say as much about the rise of the American biomedical complex as they do about their perception of research in the country. In order to illustrate how the French biologists adopted, competed with, or challenged the American model and how transatlantic exchanges played a critical role in the (...)
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  20.  9
    The Pharmaceutical Industry in the Biotech Century: Toward a History of Science, Technology and Business?Jean-Paul Gaudillière - 2001 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 32 (1):191-201.
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  21.  5
    Rockefeller Strategies for Scientific Medicine: Molecular Machines, Viruses and Vaccines.Jean-Paul Gaudillière - 2000 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 31 (3):491-509.
  22.  4
    J. Monod, S, Spiegelman and Enzymatic Adaptation. Research Programs, Local Cultures, and Disciplinary Traditions.J. P. Gaudillière - 1992 - History and Philosophy of the Life Sciences 14 (1):23.
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  23.  4
    Beat Bächi. Vitamin C für alle! Pharmazeutische Produktion, Vermarktung und Gesundheitspolitik . 275 pp., illus., tables, bibl. Zurich: Chronos Verlag, 2009. €24. [REVIEW]Jean-Paul Gaudillière - 2011 - Isis 102 (1):175-175.
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  24.  1
    ¿Biología molecular en la tradición francesa? Redefiniendo tradiciones locales y patrones disciplinares.Jean-Paul Gaudillière - 1997 - Arbor 156 (614):45-77.
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  25.  6
    Dossier Engagement public des chercheurs. Intellectuels engagés et experts : biologistes et médecins dans la bataille de l'avortement.Jean-Paul Gaudillière - 2006 - Natures Sciences Sociétés 14 (3):239-248.
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  26.  5
    Life Stories.Jean-Paul Gaudillière & Hans-Jörg Rheinberger - 2004 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 35 (4):753-764.
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  27. Localizing the Global: Testing for Hereditary Risks of Breast Cancer.Jean Paul Gaudillière & Ilana Löwy - 2008 - Science, Technology, and Human Values 33 (3):299-325.
    Tests for hereditary predispositions to breast and ovarian cancer have figured among the first medical applications of the new knowledge gleaned from the Human Genome Project. These applications have set off heated debates on general issues such as intellectual property rights. The genetic diagnosis of breast cancer risks, and the management of women “at risk” has nevertheless developed following highly localized paths. There are major differences in the organization of testing, uses of genetic tests, and the follow up of patients. (...)
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  28.  5
    Paris–New York Roundtrip: Transatlantic Crossings and the Reconstruction of the Biological Sciences in Post-War France.Jean-Paul Gaudillière - 2002 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 33 (3):389-417.
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  29.  8
    Review: Cancer and Science: The Hundred Years War. [REVIEW]Jean-Paul Gaudillière - 1998 - Journal of the History of Biology 31 (2):279 - 288.
  30.  9
    Raisons de la Folie.Jean-Max Gaudillière - 2003 - Diogène 202 (2):39.
  31.  22
    Silvia Berger. Bakterien in Krieg und Frieden: Eine Geschichte der medizinischen Bakteriologie in Deutschland, 1890–1933. 476 pp., illus., bibl., index. Göttingen: Wallstein Verlag, 2009. €48.30. [REVIEW]Jean-Paul Gaudillière - 2013 - Isis 104 (1):168-170.
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  32.  5
    The Generation of Diversity: Clonal Election Theory and the Rise of Molecular Immunology. Scott H. Podolsky, Alfred I. Tauber. [REVIEW]Jean-Paul Gaudillière - 2001 - Isis 92 (1):233-234.
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  33. The Reasons of Madness.Jean-Max Gaudillière - 2004 - Diogenes 51 (2):33-44.
    In the area of questions, or rather responses, around the subject of madness (research, treatment, etc.), ‘scientific’ rationality falls back on simple causality, together with a concern for generalization. Drawn from the pure sciences, these categories admit no exceptions, even (and particularly) if the borderlines of madness touch upon the borders of rationality. The clinical experience and rigour of working with madness may lead one to conclude that other criteria are needed. The rationalities at work in the treatment of madness (...)
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  34.  15
    Life Stories.J. Gaudilliere - 2004 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 35 (4):753-764.
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