Fecal microbiota transplantation has demonstrated efficacy and is increasingly being used in the treatment of patients with recurrent Clostridium difficile infection. Despite a lack of high-quality trials to provide more information on the long-term effects of FMT, there has been great enthusiasm about the potential for expanding its applications. However, FMT presents many serious ethical and social challenges that must be addressed as part of a successful regulatory policy response. In this article, we draw on a sample of the scientific (...) and bioethics literatures to examine clusters of ethical and social issues arising in five main areas: informed consent and the vulnerability of patients; determining what a “suitable healthy donor” is; safety and risk; commercialization and potential exploitation of vulnerable patients; and public health implications. We find that these issues are complex and worthy of careful consideration by health care professionals. Desperation of a patient should not be the basis for selecting treatment with FMT, and the patient's interests should always be of paramount concern. Authorities must prioritize development of appropriate and effective regulation of FMT to safeguard patients and donors, promote further research into safety and efficacy, and avoid abuse of the treatment. (shrink)

The recognition memory for inverted faces is especially difficult when compared with that for non-face stimuli. This face inversion effect has often been used as a marker of face-specific holistic processing. However, whether face processing without awareness is still specific remains unknown. The present study addressed this issue by examining the face inversion effect with the technique of binocular rivalry. Results showed that invisible upright faces could break suppression faster than invisible inverted faces. Nevertheless, no difference was found for invisible (...) upright houses and invisible inverted houses. This suggested that face processing without awareness is still specific. Some face-specific information can be processed by high-level brain areas even when that information is invisible. (shrink)

Past research suggests that spiritual leadership plays a pivotal role in enhancing employee job performance, yet we have little understanding of how and when spiritual leadership enhances employee job performance. The present study explores how and when spiritual leadership promotes job performance by examining relational energy as a mediator and leader integrity and relational energy differentiation as boundary conditions. We tested the theoretical model with data gathered across three phases over 12 months from 497 employees and their supervisors in 108 (...) groups. Results showed that the positive relationship between spiritual leadership and job performance was mediated by relational energy. Moreover, we found that leader integrity amplified the mediated relationship between spiritual leadership and employee job performance via relational energy. In contrast, relational energy differentiation weakened this mediated relationship. (shrink)

We prove that RCA₀ + RT $RT\begin{array}{*{20}{c}} 2 \\ 2 \\ \end{array} $ ̸͢ WKL₀ by showing that for any set C not of PA-degree and any set A, there exists an infinite subset G of A or ̅Α, such that G ⊕ C is also not of PA-degree.

_An Introduction to Chinese Philosophy_ unlocks the mystery of ancient Chinese philosophy and unravels the complexity of Chinese Buddhism by placing them in the contemporary context of discourse. Elucidates the central issues and debates in Chinese philosophy, its different schools of thought, and its major philosophers. Covers eight major philosophers in the ancient period, among them Confucius, Laozi, and Zhuangzi. Illuminates the links between different schools of philosophy. Opens the door to further study of the relationship between Chinese and Western (...) philosophy. (shrink)

Globalization has changed almost every facet of life for people around the world, and today the flow of influence is no longer uni-directional. It is argued that East Asian societies are anchored in an indigenous form of hierarchical relationalism where social structure is produced by relational obligations of an ethical and normative nature that have slowed its traditional culture “melting into air” as prophesied by Marx. The successfully modernization of East Asia has involved hybridization, compartmentalization, and sequencing of traditional psychological (...) features of Confucianist societies such as delay of gratification and respect for education, paternalistic leadership, filial piety, and beliefs in harmony or benevolence. Features of hierarchical relationalism are adaptable to creating niches for East Asian societies that thrive under globalization as characterized by the paradoxical coupling of economic inequality in fact with discourses of equality in principle. Moral, ethical demands for enlightened leadership constrain East Asian elites to at least attempt to protect subordinates and protect societal well-being. A fundamental contribution of East Asia to global society may be in the articulation of how to ameliorate economic inequality using Confucian principles of hierarchical relationalism. (shrink)

Two types of guanxi have a close association with auditor independence in China: firm-level connections derived from state ownership and personal connections developed through management affiliations with external auditors. This article examines the effects of these two types of connection and their joint effect on audit quality. We find that state ownership and management affiliations with the external auditor both increase the probability of receiving a clean audit opinion in China. Furthermore, the probability increment brought by management affiliations for non-state-owned (...) enterprises (NSOEs) is greater than that for state-owned enterprises (SOEs). These results suggest that state ownership and management affiliations are two important types of connection that impair auditor independence, and that management affiliations are of greater importance to private-sector firms than to SOEs. (shrink)

ABSTRACTThe question of the relation between humans and nature lies at the foundation of any philosophy. With the daily worsening environmental crisis, we are forced to face this ancient question again. Yet when we put it into the form of ‘humans and nature’, a metaphysics is already implied and the problem of nature has not yet been questioned. At this moment, the very question that needs to be put forward is, ‘What is nature’? The question of nature will be interrogated (...) through a comparative view in this essay. First, I argue the modern understanding of nature lies at the root of today’s environmental problems. Then, I go back to early Daoism to explore Daoist thinking on ziran. The meaning of ‘dao emulates ziran’ is brought to light through a detailed interpretation of the ziran of dao and things. Ziran penetrates the dao, the heavenly, the earthly and the human. It is with the understanding of ziran that the nature of humans and all things are illuminated. Heidegger’s... (shrink)

In the hot continuous rolling process, the main factor affecting the actual thickness of strip is the rolling force. The precision of rolling force calculation is the key to realize accurate on-line control. However, because of the complexity and nonlinearity of the rolling process, as well as many influencing factors, the theoretical analysis of the traditional rolling force prediction model often needs to be simplified and hypothesized. This leads to the incompleteness of the mathematical model and the deviation between the (...) calculated results and the actual working conditions. In this paper, a rolling force prediction method based on genetic algorithm, particle swarm optimization algorithm, and multiple hidden layer extreme learning machine is proposed, namely, PSO-GA-MELM algorithm, which takes MELM as the basic model for rolling force prediction. In the modeling process, GA is used to determine the optimal number of hidden layers and the optimal number of hidden nodes, and PSO is used to search for the optimal input weights and biases. This method avoids the influence of human intervention on the model and saves the modeling time. This paper takes the actual production data of BaoSteel 2050 production line as experimental data, and the experimental results indicate that the algorithm can be effectively used to determine the optimal network structure of MELM. The rolling force prediction model trained by the algorithm has excellent performance in prediction accuracy, computational stability, and the number of hidden nodes and is applicable to the prediction of rolling force in hot continuous rolling process. (shrink)

Understanding the neural basis of schizophrenia (SZ) is important for shedding light on the neurobiological mechanisms underlying this mental disorder. Structural and functional alterations in the anterior cingulate cortex (ACC), dorsolateral prefrontal cortex (DLPFC), hippocampus, and medial prefrontal cortex (MPFC) have been implicated in the neurobiology of SZ. However, the effective connectivity among them in SZ remains unclear. The current study investigated how neuronal pathways involving these regions were affected in first-episode SZ using functional magnetic resonance imaging (fMRI). Forty-nine patients (...) with a first-episode of psychosis and diagnosis of SZ—according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision—were studied. Fifty healthy controls (HCs) were included for comparison. All subjects underwent resting state fMRI. We used spectral dynamic causal modeling (DCM) to estimate directed connections among the bilateral ACC, DLPFC, hippocampus, and MPFC. We characterized the differences using Bayesian parameter averaging (BPA) in addition to classical inference (t-test). In addition to common effective connectivity in these two groups, HCs displayed widespread significant connections predominantly involved in ACC not detected in SZ patients, but SZ showed few connections. Based on BPA results, SZ patients exhibited anterior cingulate cortico-prefrontal-hippocampal hyperconnectivity, as well as ACC-related and hippocampal-dorsolateral prefrontal-medial prefrontal hypoconnectivity. In summary, spectral DCM revealed the pattern of effective connectivity involving ACC in patients with first-episode SZ. This study provides a potential link between SZ and dysfunction of ACC, creating an ideal situation to associate mechanisms behind SZ with aberrant connectivity among these cognition and emotion-related regions. (shrink)

This paper examines Hume’s formulations and uses of the conceivability principle and the inconceivability principle. In Hume’s works, we identify different versions of CP and ICP, including proper CP, proper ICP, the weak versions of CP and ICP, the epistemic versions of CP and ICP, and show that Hume not only expresses ICP, but also really maintains it. Assuming an axiomatic characterization of modalities, we argue that if there is a sharp distinction between levels of modalities, then Hume’s conceivability arguments (...) do not hold. But, in a rather different way, we also argue that if Hume’s conceivability arguments hold, then there should be no distinction between levels of modalities. Finally, we argue that after Hume, there are lots of endeavors in logic and philosophy to distinguish different levels of modalities, and to accept new concepts of necessity other than logical necessity. (shrink)

This essay questions the meaning of be-ing and non-be-ing in the DDJ with regard to the root-source meaning of dao. I first explore the meaning of dao as the dark non-be-ing, revealing the connotations of the distinction between dao and things by comparison with some forms of Western metaphysics. The meaning of non-be-ing is elaborated in terms of the dynamic meanings of xu 虚 and chong 沖; The play between be-ing and non-be-ing is explored through the lens of yin and (...) yang qi thinking. Qi thinking determines the mutually manifest and mutually interpretive characteristic of be-ing and non-be-ing. Be-ing and non-be-ing thus understood is an ever-flowing and mutually transforming process that penetrates the different levels of dao, things and humans. In the last part I investigate the meaning of “Be-ing comes from non-be-ing”. (shrink)

This paper begins with Thomas Nagel's (1970) investigation of the possibility of altruism to further examine how to motivate altruism. When the pursuit of the gratification of one's own desires generally has an immediate causal efficacy, how can one also be motivated to care for others and to act towards the well-being of others? A successful motivational theory of altruism must explain how altruism is possible under all these motivational interferences. The paper will begin with an exposition of Nagel's proposal, (...) and see where it is insufficient with regard to this further issue. It will then introduce the views of Zhang Zai and Wang Fuzhi, and see which one could offer a better motivational theory of altruism. All three philosophers offer different insights on the role of human reason/reflection and human sentiments in moral motivation. The paper will end with a proposal for a socioethical moral program that incorporates both moral reason and moral sentiments as motivation. (shrink)

In Why Be Moral: Learning from the Neo-Confucian Cheng Brothers, Yong Huang presents a comparative study on the moral philosophy of the Cheng brothers as how comparative philosophy should be done: to engage in contemporary philosophical problems and to propose solutions that could be gleaned from the ideas of ancient Chinese philosophers. His analysis provides a paradigm for comparative philosophy. I think this is the right way to do comparative philosophy—to focus on problem solving rather than textual comparison. I am (...) very impressed both with the breadth of his knowledge of Western moral philosophy and with the depth of his analysis of the moral philosophy of the Cheng brothers. Since I share his view on how to... (shrink)

Putnam and Burge have been viewed as launching a joint attack on individualism, the view that the content of one's psychological state is determined by what is in the head . Putnam argues that meanings are not in the head while Burge argues that beliefs are not in the head either, and both have come up with convincing arguments against individualism. It is generally conceived that Putnam's view is a version of physical externalism, which argues that factors in the physical (...) environment play a role in determining the meanings of natural kind terms. Burge, on the other hand, is regarded as following up Putnam's argument to bring in factors in the social environment for the determination of belief. Burge's view has been commonly referred to as 'social externalism.' The general consensus in the field is that physical externalism and social externalism are compatible views. Furthermore, both Putnam and Burge seem to endorse each other’s position for the most part. In this paper, however, I shall argue against this general view to show that the two theories are deep down incompatible. (shrink)

___ (i) There is a difference between hearing Clyde play the piano and seeing him play the piano. ___ (ii) A perceptual belief that he is playing the piano must also be distinguished from a perceptual experience of this same event.

OBJECTIVE: To report and analyse the pattern of end-of-life decision making for terminal Chinese cancer patients. DESIGN: Retrospective descriptive study. SETTING: A cancer clinical trials unit in a large teaching hospital. PATIENTS: From April 1992 to August 1997, 177 consecutive deaths of cancer clinical trial patients were studied. MAIN MEASUREMENT: Basic demographic data, patient status at the time of signing a DNR consent, or at the moment of returning home to die are documented, and circumstances surrounding these events evaluated. RESULTS: (...) DNR orders were written for 64.4% of patients. Patients in pain (odds ratio 0.45, 95% CI 0.22-0.89), especially if requiring opioid analgesia (odds ratio 0.40, 95% CI 0.21-0.77), were factors associated with a higher probability of such an order. Thirty-five patients were taken home to die, a more likely occurrence if the patient was over 75 years (odds ratio 0.12, 95% CI 0.04-0.34), had children (odds ratio 0.14, 95% CI 0.02-0.79), had Taiwanese as a first language (odds ratio 6.74, 95% CI 3.04-14.93), or was unable to intake orally (odds ratio 2.73, 95% CI 1.26-5.92). CPR was performed in 30 patients, none survived to discharge. CONCLUSIONS: DNR orders are instituted in a large proportion of dying Chinese cancer patients in a cancer centre, however, the order is seldom signed by the patient personally. This study also illustrates that as many as 20% of dying patients are taken home to die, in accordance with local custom. (shrink)

This paper calls for a reconstruction of Chinese metaphysics that recognizes the distinct features of Chinese worldview, while at the same time explores the speculative thinking behind the dominant ethical concerns in Chinese philosophy. It suggests some research topics for constructing a Chinese moral metaphysics, without turning it into a metaphysical ethics – the difference between the two is that the former is fundamentally “truth-pursuing” while the latter is “good-pursuing.” This paper argues that even though Chinese metaphysics is deeply connected (...) with concerns for human flourishing, it is not just a study of nature for the sake of practical living. Furthermore, although Chinese metaphysics is different from traditional Western metaphysics, it is not incommensurable with it. There are many interesting metaphysical topics that can be investigated within Chinese philosophical texts. This is a project that looks in to the future of the development of Chinese metaphysics, not a backward-looking study into the history of Chinese cosmological thinking. (shrink)

A variety of crucial and still most relevant ideas about nothingness or emptiness have gained profound philosophical prominence in the history and development of a number of South and East Asian traditions—including in Buddhism, Daoism, Neo-Confucianism, Hinduism, Korean philosophy, and the Japanese Kyoto School. These traditions share the insight that in order to explain both the great mysteries and mundane facts about our experience, ideas of "nothingness" must play a primary role. This collection of essays brings together the work of (...) twenty of the world’s prominent scholars of Hindu, Buddhist, Daoist, Neo-Confucian, Japanese and Korean thought to illuminate fascinating philosophical conceptualizations of "nothingness" in both classical and modern Asian traditions. The unique collection offers new work from accomplished scholars and provides a coherent, panoramic view of the most significant ways that "nothingness" plays crucial roles in Asian philosophy. It includes both traditional and contemporary formulations, sometimes putting Asian traditions into dialogue with one another and sometimes with classical and modern Western thought. The result is a book of immense value for students and researchers in Asian and comparative philosophy. (shrink)

ABSTRACTRecent decades have brought global expansion of private supplementary tutoring, and China is among countries in which patterns have been especially dramatic. National survey data indicate t...

Nanotechnology shows great promise in a variety of applications with attractive economic and societal benefits. However, societal issues associated with nanotechnology are still a concern to the general public. While numerous technological advancements in nanotechnology have been achieved over the past decade, research into the broader societal issues of nanotechnology is still in its early phases. Based on the data from the Web of Science database, we applied the main path analysis, cluster analysis and text mining tools to explore the (...) main research fronts and hierarchical structure of these societal issues. We found that the research studies fell into four categories: "General Toxicity and EHS (Environment, Health and Safety)," "Medicine and Cytotoxicity," "Assessment and Regulation," and "Environment and Ecotoxicity." These research studies have disclosed much information about the potential effect of nanotechnology on public health and the environment. Relatively speaking, the studies on the assessment, regulation, preventive solutions, and environmental protection are just emerging. This finding indicates that an abundance of effort should be conducted on these emerging themes to maximize the benefits of nanotechnology while minimizing its potential harm. The implications for various parties in this domain are also presented. (shrink)

In this paper I construct Confucian moral realism as a metaethical theory that is compatible with, or even derivable from, traditional Confucianism. The paper is at once interpretative and constructive. In my analysis, Confucians can establish the realist's claims on moral properties because they embrace the view of a moralistic universe. Moral properties in Confucian ethics not only are presented as objective, naturalistic properties, but also are seen as 'causally efficacious'. There are several theses commonly endorsed by contemporary moral realists. (...) I will explain how many of the remarks by Confucius, Mencius, in Yijing, The Great Learning and The Doctrine of the Mean can be understood as implicit endorsements of these theses. I will also analyze the theses specific to Confucian moral realism. The paper will end with a brief defense of this form of realism. (shrink)

In traditional Chinese cosmology, this pattern could be very well explained in terms of the fluctuation of yin and yang, or as the natural order of Heaven. This cosmological explanation fits natural history well. There are natural phenomena such as floods, draughts, hurricanes, tornadoes, earthquakes, etc., that are beyond human control. These events have their determining factors. Once those factors are present, a natural disaster, however unfavorably viewed by humans, is doomed to take place. The view that natural history is (...) determined by factors outside the human world can be accepted without much controversy. However, when applied to human history, the role of man in human history becomes problematic under this kind of cosmology. How much of our success or failure is due to our larger cosmological environment -- the ongoing development of the chi'? Can a single individual reverse the flow of yin and yang or the emergence of good times and bad times? On a larger scale, is human history predestined? If there is a necessary rotation of prosperity and chaos, then it can be argued that.. (shrink)

In this paper, I shall present a comparative study of two leading Daoists’ different conceptions of truth in the context of modern metaphysical debate on realism and antirealism. My basic contention in this paper is that both Laozi and Zhuangzi embrace the realist's thesis that the world is largely independent of us and the way we are; it has its own objective nature.

Chinese philosophy has its roots in religion, and has spread to the general Chinese public as a mixture of attitudes in life, cultural spirit, as well as religious practices. However, Chinese philosophy is not just a collection of wisdom on life or a religious discourse on how to lead a good life; it is also a form of philosophy. And yet its philosophical import has often been slighted in the Western philosophical world. Two hundred years ago, Hegel remarked that there (...) is no separation between philosophy and religion in the East: “That which we call Eastern Philosophy is more properly the religious mode of thought and the conception of the world belonging generally to the Orientals and approximates very closely to Philosophy.” (Hegel, Lectures on the History of Philosophy, Vol. 1) Under this conception, Hegel’s attitude with Chinese philosophy was completely dismissive. He described Confucius as “only a man who has a certain amount of practical and worldly wisdom — one with whom there is no speculative philosophy,” and “it would have been better had [his works] never been translated.” With Laozi’s conception of ‘dao,’ Hegel commented: “to the Chinese what is highest and the origin of things is nothing, emptiness, the altogether undetermined, the abstract universal,” and “if.. (shrink)

In this paper, I attempt to make use of Western metaphysical taxonomy to explicate the cosmological variances in Chinese philosophical schools, especially with regard to the debates among the Neo-Confucian thinkers. While I do not presume that Chinese philosophers dealt with the same Western issues, I do believe that a comparative study of this nature can point to a new direction of thinking concerning the metaphysical debates in Neo-Confucianism. This paper is divided into three parts. In Part I, I employ (...) Robert Nozick’s notion of natural cosmic state to analyze the fundamental difference between the Confucian and Daoist cosmologies. Even though this notion of natural cosmic state has no comparable match in Chinese philosophy, it may serve as a schematizing device for our comparative study of Chinese cosmology. In Part II, I employ Nicholas Rescher’s distinction between “laws of nature” and “laws for nature” to analyze the debate on the status of cosmic principle a between Zhou Dunyib and Zhu Xic on the one hand, and Zhang Zaid and Wang Fuzhie on the other. 1 In Part III, I employ the notion of supervenience, as defined by Jaegwon Kim, to argue that in the debate on the status of cosmic principle, it is Zhang Zai and Wang Fuzhi’s view that better preserves the causal relevance of cosmic principle. (shrink)

The oscillations on output power and distortion of the inverter currents will occur in the case of unbalanced grid voltage faults. Constant output power and good current quality cannot be achieved simultaneously. Aiming at these problems, a coordinate control strategy for suppressing power fluctuations and current harmonics is proposed by analyzing instantaneous power control and current balance control. The proposed control is achieved by adjusting the weight coefficient of current reference values to change the current harmonic contents based on proportional (...) complex integral controller and proportional multiple complex integral controller. The control strategy with a simple control structure neither needs to detect harmonic components of the inverter currents, nor needs to separate the positive and negative components of voltage and current, which is easy to be realized. The feasibility and effectiveness of the proposed control are verified by the comparison and analysis of simulation. (shrink)