Medical practice should evolve alongside medical ethics. As our understanding of the ethical implications of physician-patient interactions becomes more nuanced, physicians should integrate those lessons into practice. As early as the 1930s, epidemiological studies began to identify that the rates of medical procedures varied significantly along geographic and socioeconomic lines. Dr. J. Alison Glover recognized that tonsillectomy rates in school children in certain school districts in England and Wales were in some cases eight times the rates of children in other (...) districts, with the only significant predictive factors being the current chief medical officer in the area and the socioeconomic well-being of the child's parents. Unfortunately, Dr. Glover's work revealed that the increase in tonsillectomies did not improve the health of adolescent patients and appeared to be performed “as a routine prophylactic ritual for no particular reason and with no particular result.”. (shrink)

Clinical evidence suggests that many patients undergo surgery that they would decline if fully informed. Failure to communicate the relevant risks, benefits, and alternatives of a procedure violates medical ethics and wastes medical resources. Integrating shared decision-making, a method of communication between provider and patient, into medical decisions can satisfy physicians' ethical obligations and reduce unwanted procedures. This article proposes a three-step process for implementing a nationwide practice of shared decision-making: create model integration programs; provide legal incentives to ease the (...) transition; and incorporate shared decision-making into medical necessity determinations. (shrink)

Current methods of obtaining an informed consent leave much to be desired. Patients rarely read consent forms or understand all of the risks, benefits, or alternatives associated with their treatment. Evaluating the advantages and disadvantages of treatment options often presents a more significant challenge for patients with lower levels of health literacy. This article reviews the evidence of shortcomings in our informed consent system and then explores the potential for a new approach to engage patients at all levels of health (...) literacy in their treatment decisions. Specifically, the article will examine the potential of shared decision-making to bridge gaps in knowledge, increase patient adherence to treatment, and improve health outcomes in low health literacy patient populations. Leveling barriers to treatment information for disadvantaged populations should be a public health imperative, especially if it can be shown to improve health outcomes and reduce health disparities. (shrink)

Current methods of obtaining an informed consent leave much to be desired. Patients rarely read consent forms or understand all of the risks, benefits, or alternatives associated with their treatment. Evaluating the advantages and disadvantages of treatment options often presents a more significant challenge for patients with lower levels of health literacy. This article reviews the evidence of shortcomings in our informed consent system and then explores the potential for a new approach to engage patients at all levels of health (...) literacy in their treatment decisions. Specifically, the article will examine the potential of shared decision-making to bridge gaps in knowledge, increase patient adherence to treatment, and improve health outcomes in low health literacy patient populations. Leveling barriers to treatment information for disadvantaged populations should be a public health imperative, especially if it can be shown to improve health outcomes and reduce health disparities. (shrink)

Chrysippus claims that some propositions perish. including some true conditionals whose consequent is impossible and antecedent is possible, to which he appeals against Diodorus?s Master Argument. On the standard interpretation. perished propositions lack truth values. and these conditionals are true at the same time as their antecedents arc possible and consequents impossible. But perished propositions are false, and Chrysippus?s conditionals are true when their antecedent and consequent arc possible, and false when their antecedent is possible and consequent impossible. The claim (...) of the Master Argument that Chrysippus rejects, then, is stronger ihan usually supposed. (shrink)

This paper studies the topology of the Chilean mutual fund industry using networks methods. With the physical positions of the local equity portfolios managed during 2003.01-2017.4, we analyze their connectivity structure in both the mutual funds’ bipartite network and their one-mode projection. We estimate network measures to examine the potential effects on the topology arising from changes in the industrial environment and changes in the mutual funds’ investment strategies in their overlapped portfolios. Our main results show that changes in the (...) bipartite network and its one-mode projection are correlated with variables related to funds’ investment strategies and with industry-specific variables. In consequence, these elements are a new potential of disturbance in the financial network conformed by stocks and mutual funds. We contribute to the existing literature, improving the understanding of the aggregate behavior of a financial sector which despite its economic importance has attracted little attention from a systemic risk perspective. (shrink)

We deal with the consistency strength of ZFC + variants of MA + suitable sets of reals are measurable (and/or Baire, and/or Ramsey). We improve the theorem of Harrington and Shelah [2] repairing the asymmetry between measure and category, obtaining also the same result for Ramsey. We then prove parallel theorems with weaker versions of Martin's axiom (MA(σ-centered), (MA(σ-linked)), MA(Γ + ℵ 0 ), MA(K)), getting Mahlo, inaccessible and weakly compact cardinals respectively. We prove that if there exists r ∈ (...) R such that ω L[ r] 1 = ω 1 and MA holds, then there exists a ▵ 1 3 -selective filter on ω, and from the consistency of ZFC we build a model for ZFC + MA(I) + every ▵ 1 3 -set of reals is Lebesgue measurable, has the property of Baire and is Ramsey. (shrink)

The American Journal of Bioethics, Volume 12, Issue 7, Page 32-33, July 2012.

Thirty years ago Richard Rorty detected the similarities between Wittgenstein's Philosophical Investigations (1953) and the philosophical framework of Charles S. Peirce (1839-1914), the founder of pragmatism. Rorty tried to show that Peirce envisaged and repudiated in advance logical positivism and developed insights and a philosophical mood very close to the analytical philosophers influenced by the later Wittgenstein (Rorty 1961). In spite of that, the majority of scholars have considered both thinkers as totally alien. Some scholars have attributed the pragmatist flavor (...) of the Philosophical Investigations to the influence of Frank P. Ramsey, who awoke Wittgenstein from the dogmatic slumber of the Tractatus. Nevertheless, the real scope of the influence of American pragmatist philosophy in Wittgenstein's later thought is not clearly known. The purpose of my paper is not to describe the common themes between Wittgenstein and Peirce, but the way in which recent scholarship has established some links between both philosophers. -/- . (shrink)

Se examina la posición de M. Heidegger sobre el sentido ontológico de la corporalidad, como respuesta a la interpelación de aquello que se le presenta al Dasein debido a su constitución abierta al mundo. Esto lleva a preguntarse sobre la actuación corporal y técnica sobre el mundo, y sobre los otros, o al problema del cuerpo animal. Se confronta finalmente la perspectiva heideggeriana con la teoría del cuerpo subjetivo o trascendental de M. Henry, donde la apertura ontológica es reemplazada por (...) una fenomenología de la vida aplicada al cuerpo vivo como corporalidad encarnada. The article examines M. Heidegger's position regarding the ontological sense of corporality understood as an answer to the interpellation of that which presents itself to Dasein due to its constitution as being open to the world. This leads to questions regarding the corporal and technical action on the world and others, or the problem of the animal body. Finally, the article confronts Heidegger's perspective with M. Henry's theory of the subjective or transcendental body, in which the ontological openness is replaced by a phenomenology of life applied to the living body as an embodied corporality. (shrink)

Charles S. Peirce (1839-1914) made relevant contributions to deductive logic, but he was primarily interested in the logic of science, and more especially in what he called 'abduction' (as opposed to deduction and induction), which is the process whereby hypotheses are generated in order to explain the surprising facts. Indeed, Peirce considered abduction to be at the heart not only of scientific research, but of all ordinary human activities. Nevertheless, in spite of Peirce's work and writings in the field of (...) methodology of research, scarce attention has been paid to the logic of discovery over the last hundred years, despite an impressive development not only of scientific research but also of logic. -/- Having this in mind, the exposition is divided into five parts: 1) a brief presentation of Peirce, focusing on his work as a professional scientist; 2) an exposition of the classification of inferences by the young Peirce: deduction, induction and hypothesis; 3) a sketch of the notion of abduction in the mature Peirce; 4) an exposition of the logic of surprise; and finally, by way of conclusion, 5) a discussion of this peculiar ability of guessing understood as a rational instinct. -/- . (shrink)

A surprising fact in the historiography of the Hispanic philosophy of this century is its almost total opacity towards the American philosophy, in spite of the real affinity between the central questions of American pragmatism and the topics addressed by the most relevant Hispanic thinkers of the century: Unamuno, Ortega y Gasset, d'Ors, Vaz Ferreira. In this paper that situation is studied, paying special attention to Charles S. Peirce, his personal connections with the Hispanic world, the reception of his texts (...) in Spanish, and some of the connections that lie almost hidden under the mutual ignorance which divides the two traditions. -/- . (shrink)

In 2007. Terence Tao wrote on his blog an essay about soft analysis, hard analysis and the finitization of soft analysis statements into hard analysis statements. One of his main examples was a quasi-finitization of the infinite pigeonhole principle IPP, arriving at the "finitary" infinite pigeonhole principle FIPP₁. That turned out to not be the proper formulation and so we proposed an alternative version FIPP₂. Tao himself formulated yet another version FIPP₃ in a revised version of his essay. We give (...) a counterexample to FIPP₁ and discuss for both of the versions FIPP₂ and FIPP₃ the faithfulness of their respective finitization of IPP by studying the equivalences IPP ↔ FIPP₂ and IPP ↔ FIPP₃ in the context of reverse mathematics ([9]). In the process of doing this we also introduce a continuous uniform boundedness principle CUB as a formalization of Tao's notion of a correspondence principle and study the strength of this principle and various restrictions thereof in terms of reverse mathematics, i.e., in terms of the "big five" subsystems of second order arithmetic. (shrink)

We adapt Streicher and Kohlenbach's proof of the factorization S = KD of the Shoenfield translation S in terms of Krivine's negative translation K and the Gödel functional interpretation D, obtaining a proof of the factorization U = KB of Ferreira's Shoenfield-like bounded functional interpretation U in terms of K and Ferreira and Oliva's bounded functional interpretation B.

The aim of my paper is to highlight that for Peirce the reality of God makes sense of the whole scientific enterprise. The belief in God is a natural product of abduction, of the "rational instinct" or educated guess of the scientist or the layman, and also the abduction of God may be understood as a "proof" of pragmatism. Moreover, I want to suggest that for Peirce scientific activity is a genuine religious enterprise, perhaps even the religious activity par excellence, (...) and that to divorce religion from science is antithetical to both the scientific spirit and the real Peirce. Understanding the real Peirce requires to deal with his religious concerns, which are increasingly recognized as being perhaps as philosophically important as his scientific concerns. Since a key notion in this project is the idea of "il lume naturale" that Peirce borrowed from Galileo, I want also to pay attention to that expression which during years I have been following through Peirce's papers and books. -/- In order to try to explain some of this, my paper is arranged into four brief sections after this already long introduction: 1) God and scientific inquiry; 2) The belief in God as a product of abduction; 3) Galileo and Peirce: Il lume naturale; and by way of conclusion 4) Some remarks on the religious framework of Peirce's approach. (shrink)

We define the notion of Souslin forcing, and we prove that some properties are preserved under iteration. We define a weaker form of Martin's axiom, namely MA(Γ + ℵ 0 ), and using the results on Souslin forcing we show that MA(Γ + ℵ 0 ) is consistent with the existence of a Souslin tree and with the splitting number s = ℵ 1 . We prove that MA(Γ + ℵ 0 ) proves the additivity of measure. Also we introduce (...) the notion of proper Souslin forcing, and we prove that this property is preserved under countable support iterated forcing. We use these results to show that ZFC + there is an inaccessible cardinal is equiconsistent with ZFC + the Borel conjecture + Σ 1 2 -measurability. (shrink)

Connections between J.L.Vives and C.S. Peirce are shown. Not only is reflec-tion on language and meaning central in both thinkers, but Peirce also knew Vives' thought especially through W. Hamilton and the Scottish common sense school. Peirce credited Vives with being a forerunner of the use of dia-grams in logic, and both share a critical view of late medieval nominalistic logicians and a social and hierarchical conception of knowledge.

Dijkstra and Scholten have proposed a formalization of classical predicate logic on a novel deductive system as an alternative to Hilbert's style of proof and Gentzen's deductive systems. In this context we call it CED (Calculus of Equational Deduction). This deductive method promotes logical equivalence over implication and shows that there are easy ways to prove predicate formulas without the introduction of hypotheses or metamathematical tools such as the deduction theorem. Moreover, syntactic considerations (in Dijkstra's words, "letting the symbols do (...) the work") have led to the "calculational style," an impressive array of techniques for elegant proof constructions. In this paper, we formalize intuitionistic predicate logic according to CED with similar success. In this system (I-CED), we prove Leibniz's principle for intuitionistic logic and also prove that any (intuitionistic) valid formula of predicate logic can be proved in I-CED. (shrink)

Dijkstra and Scholten have proposed a formalization of classical predicate logic on a novel deductive system as an alternative to Hilbert's style of proof and Gentzen's deductive systems. In this context we call it CED . This deductive method promotes logical equivalence over implication and shows that there are easy ways to prove predicate formulas without the introduction of hypotheses or metamathematical tools such as the deduction theorem. Moreover, syntactic considerations have led to the "calculational style," an impressive array of (...) techniques for elegant proof constructions. In this paper, we formalize intuitionistic predicate logic according to CED with similar success. In this system , we prove Leibniz's principle for intuitionistic logic and also prove that any valid formula of predicate logic can be proved in I-CED. (shrink)

The aim of this paper is to describe Dewey’s reception in the Spanish-speaking countries that constitute the Hispanic world. Without any doubt, it can be said that in the past century Spain and the countries of South America have been a world apart, lagging far behind the mainstream Western world. It includes a number of names and facts about the early translation of Dewey’s works in Spain, Chile, Cuba, Mexico and Argentina in the first half of the century and a (...) brief explanation of the decline of Dewey in the second half. To a great extent, Dewey’s conception of education was immersed in the international movement of reform that started at the turn of the century and would eventually slowly but surely, renovate the structure of the educational system throughout the entire century, including that of South America. But it is equally clear that the Spanish-speaking countries have displayed a general ignorance of Dewey and, by extension, of American pragmatism during most of the century. In spite of mutual incomprehension, a deep affinity between Dewey’s pragmatism and Hispanic philosophy is suggested in this paper, anticipating that the gradual process of democratization of Spain and the Hispanic countries of South America may be in some sense related to the rediscovery of Dewey and to the application of his key ideas in education. After decades of neglect of Dewey and of his contribution, there is a strong feeling not only that his conception of things is important to understand the last century but that Dewey – along with Peirce and other American classical pragmatists – may very well prove to be a key thinker for the XXIst century also in the Hispanic world. Along this vein, the recent resurgence of pragmatism can be understood not as the latest academic fashion but the occasion to start to close the gap between the two worlds. (shrink)

Is the societal-level of analysis sufficient today to understand the values of those in the global workforce? Or are individual-level analyses more appropriate for assessing the influence of values on ethical behaviors across country workforces? Using multi-level analyses for a 48-society sample, we test the utility of both the societal-level and individual-level dimensions of collectivism and individualism values for predicting ethical behaviors of business professionals. Our values-based behavioral analysis indicates that values at the individual-level make a more significant contribution to (...) explaining variance in ethical behaviors than do values at the societal-level. Implicitly, our findings question the soundness of using societal-level values measures. Implications for international business research are discussed. (shrink)

"I do not call the solitary studies of a single man a science. It is only when a group of men, more or less in intercommunication, are aiding and stimulating one another by their understanding of a particular group of studies as outsiders cannot understand them, that call their life a science”. (MS 1334: 12–13, 1905). This beautiful quotation from Charles S. Peirce comes from his “Lecture I to the Adirondack Summer School 1905” and was catalogued as MS 1334 (Robin (...) 1967). In 1986 Kenneth L. Ketner chose fifteen pages (7–22) of the Notebook I of these lectures to represent Peirce’s conception of science in the volume Classical American Philosophy (Stuhr 1987: 46–48). “The Nature of Science” was the appropriate title assigned to that selection, which up to then had been almost unknown to the majority of Peirce scholars. Sara Barrena translated the piece into Spanish in 1996 (Barrena 1996: 1435–1440) and we chose the quotation above as the motto for our then incipient group of Peirce scholars in the Spanish- speaking world because it so finely expressed the aim of our undertaking. Against the traditional image of the philosopher as a solitary thinker near the stove, we wanted, following Peirce, to encourage cooperation and communication between our researchers not only as something useful, but as something essential for the real development of science. (shrink)

Self-enhancement is the biasing of one’s view of oneself in a positive direction. The brain correlates of self-enhancement remain unclear though it has been reported that the medial prefrontal cortex may be important for producing self-enhancing responses. Previous studies have not examined whether the neural correlates of self-enhancement depend on the particular domain in which individuals are enhancing themselves. Both moralistic and egoistic words were presented to participants while transcranial magnetic stimulation was applied to the MPFC, precuneus or in a (...) sham orientation. Participants were asked to make decisions as to the words describing themselves, some of which were positive and some of which were negative. It was found the MPFC TMS significantly disrupted egoistic self-enhancement when TMS was delivered to the MPFC. Judgments involving moralistic words were not influenced by TMS. These data provide further evidence that MPFC is involved in self-enhancement, and that the role of MPFC may be selective in this regard. (shrink)

In a world of ever growing specialization, the idea of a unity of science is commonly discarded, but cooperative work involving cross-disciplinary points of view is encouraged. The aim of this paper is to show with some textual support that Charles S. Peirce not only identified this paradoxical situation a century ago, but he also mapped out some paths for reaching a successful solution. A particular attention is paid to Peirce's classification of the sciences and to his conception of science (...) as a collective and cooperative activity of all those whose lives are animated by the desire to discover the truth. -/- . (shrink)

The article focuses on the concept of reasonableness as described by American philosopher Charles S. Peirce in his writings dating between 1899 and 1908. Pierce's writings considered by the author are found in the books "Contributions to The Nation," vols. 1-4, edited by K. L. Ketner and J. E. Cook, and "Collected Papers of Charles Sanders Peirce," vols. 1-8, edited by C. Hartshorne, P. Weiss and A. W. Burks. The author considers 20th century Western philosophies of reason, pragmatism, scientism, thirdness, (...) postmodernism, and philosopher Walker Percy's criticisms of Peirce's arguments regarding reasonableness. (shrink)

The relationship between William James and Ludwig Wittgenstein (1889-1951) has recently been the subject of intense scholarly research. We know for instance that the later Wittgenstein's reflections on the philosophy of psychology found in James a major source of inspiration. Not surprisingly therefore, the pragmatist nature of the philosophy of the later Wittgenstein is increasingly acknowledged, in spite of Wittgenstein’s adamant refusal of being labeled a “pragmatist”. In this brief paper I merely want to piece together some of the available (...) evidence of Wittgenstein’s high regard for William James, not only for his thoughts, but even more so for his character. (shrink)

This opinion paper takes aim at an error made recently by Clarivate Analytics in which it sent out an email that congratulated academics for becoming exclusive members of academia’s most cited elite, the Highly Cited Researchers. However, that email was sent out to an undisclosed number of non-HCRs, who were offered an apology shortly after, through a bulk mail, which tried to down-play the importance of the error, all the while praising the true HCRs. When Clarivate Analytics senior management was (...) contacted, the company declined to offer an indication of the number of academics who had been contacted and erroneously awarded the HCR status. We believe that this regrettable blunder, together with the opacity offered by the company, fortify the corporate attitude about the value of the journal impact factor, and what it represents, namely a marketing tool that is falsely used to equate citations with quality, worth, or influence. The continued commercialization of metrics such as the JIF is at the heart of their use to assess the “quality” of a researcher, their work, or a journal, and contributes to a great extent to driving scientific activities towards a futile endeavor. (shrink)

Bertrand Russell was never to forget the course he gave in Barcelona in the spring of 1920. In the bitter title-page of An Inquiry into Meaning and Truth (1940), after the legal ruling which had suspended him from teaching at City College, New York, he expressly mentions his lectures in Barcelona, along with those he had given at the Universities of Uppsala and Copenhagen and at the Sorbonne. He also alludes briefly to them in his Autobiography (Russell 1990, II, 143), (...) but their circumstances and import have received no attention to date. The aim of this paper is to bring to light the available information on this subject in the Russell Archives (McMaster University, Canada) and the papers left by Joan Crexells (1896-1926) and Eugenio d'Ors (1881-1954), the two Catalan philosophers behind Russell's visit, and to put forward an assessment of Russell's influence on Spanish philosophy. (shrink)

Challenging the public dichotomy characterizing fathers as “involved” or “absentee,” we investigate racial variation in college men’s perceptions of their paternal relationships and the gendered constructions these promote. The analysis draws on intensive interviews with Asian American, Black, and white sons from one university and survey data from 24 institutions. In both data sets, Asian Americans and Blacks describe greater paternal distance than do whites. This conceals variations in sons’ understanding of fathers. Asian Americans often criticize their fathers’ distance, disidentifying (...) with the near-exclusive focus on breadwinning they describe among fathers. In contrast, Blacks and whites normalize and identify with their dads. Blacks emphasize the “laid-back,” “cool” masculinity their dads impart, while whites often emphasize the independent masculinity based on mentorship and friendship their dads offer. Recasting sociological theories, we argue these differences emanate from divergent structural contexts, but more importantly, cultural conceptions of fatherhood, race, and gender as well as public discussions that valorize white models of fatherhood. (shrink)

This article is an attempt to develop a theory of peace education through an examination of the Fukushima Daiichi nuclear disaster. It examines why Japan did not avoid this terrible nuclear disaster. This is an educational issue, because one of the major impacts of Fukushima's catastrophe is that it indicates the failure of peace education. In order to reestablish a theory of peace education, the concept of domestic tranquility is discussed. This article questions whether the Japanese public order is consistent (...) with democratic principles. Jane Roland Martin's examination of the concept of domestic tranquility is shown relevant. Martin's language analysis helps to distinguish whether or not Japanese domestic tranquility under nuclear crisis is democratic. I propose that post-Fukushima disaster peace education should be reformed as consistent with two democratic principles: acceptance of the diversity of peace and continuous negotiation among these different narratives. (shrink)

Connections between W. James and L. Wittgenstein have been widely highlighted in recent scholarship: his mature reflections on the philosophy of psychology found in James a major source of inspiration. This paper gives reason of Wittgenstein's refusal to being labelled "pragmatist" and stresses -against Schulte- the influential role of James in the development of Wittgenstein's thought.

Publishing has become, in several respects, more challenging in recent years. Academics are faced with evolving ethics that appear to be more stringent in a bid to reduce scientific fraud, the emergence of science watchdogs that are now scrutinizing the published literature with critical eyes to hold academics, editors and publishers more accountable, and a barrage of checks and balances that are required between when a paper is submitted and eventually accepted, to ensure quality control. Scientists are often under increasing (...) pressure to produce papers in an increasingly stringent publishing environment. In such a climate, timing is everything, as is the efficiency of the process. Academics appreciate that rejections are part of the fabric of attempting to get a paper published, but they expect the reason to be clear, based on careful evaluation of their work, and not on superficial or unsubstantiated excuses. A desk rejection occurs when a paper gets rejected even before it has entered the peer review process. This paper examines the features of some desk rejections and offers some guidelines that would make desk rejections valid, fair and ethical. Academics who publish are under constant pressure to do so quickly, but effectively. They are dependent on the editors’ good judgment and the publisher’s procedures. Unfair, unsubstantiated, or tardy desk rejections disadvantage academics, and editors and publishers must be held accountable for wasting their time, resources, and patience. (shrink)

Gregory Bateson is well known for defining information by stating “In fact what we mean by information – the elementary unit of information – is a difference which makes a difference…” This conceptual perspective has the merit of simplicity and generality. Simplicity, in addressing the complexity of information. Generality, in seeking applicability to any and every field of human experience. The purpose of this paper is to focus the applicability of this conceptual approach by Bateson and use it to perform (...) a calculation of taking the difference between two grey-level digital images that are shifted one relative to the other. The digital images take the place of the field of view that a human being would have access through her sense of vision at two different spatial/temporal instances. The results show that it is possible to highlight the edges of the objects under scrutiny, as well as to highlight other differences within the object. Bateson’s “difference that makes a difference” would seem to provide a first step in the elusive meaning making process of humans. (shrink)

In this paper Peirce's notion of sign is studied to try to characterize the artistic sign as representation. Then, some considerations about the work of art as a sign are developed involving three elements: experience, expression and interpretation. Finally it is concluded that beauty requires for Peirce a peculiar balance, the imaginative conjunction of the sensible and the reasonable in an artistic sign; it requires moreover the expression of something that transcends the sensible; it requires, as a sign, an interpretation (...) which is not exact and which implies growth. It requires, finally, love, because an artist will only reach beauty guided by agape updating and harmonizing possibilities through abduction, that is, creating new signs that give form to what does not have it; the artist only reaches beauty when he loves what he does and when he can express himself freely. -/- En este artículo se estudia, en primer lugar, la noción de signo de Peirce para tratar de caracterizar después el signo artístico como representación. Se desarrollan enseguida algunas consideraciones sobre la obra de arte como signo que como tal conlleva tres elementos: experiencia, expresión e interpretación. Finalmente se concluye que la belleza requiere para Peirce un peculiar equilibrio, la conjunción imaginativa de lo sensible y lo razonable en un signo artístico; requiere además la expresión de algo que trasciende lo sensible; requiere, en tanto signo, de una interpretación que no es exacta y que implica crecimiento. Requiere, por último, amor, pues el artista solo alcanzará lo bello cuando sea guiado por el ágape y a través de la abducción vaya actualizando y armonizando posibilidades, creando nuevos signos que den forma a lo que no la tiene, cuando ame lo que hace y se exprese libremente. (shrink)

The INBIOSA project brings together a group of experts across many disciplines who believe that science requires a revolutionary transformative step in order to address many of the vexing challenges presented by the world. It is INBIOSA’s purpose to enable the focused collaboration of an interdisciplinary community of original thinkers. This paper sets out the case for support for this effort. The focus of the transformative research program proposal is biology-centric. We admit that biology to date has been more fact-oriented (...) and less theoretical than physics. However, the key leverageable idea is that careful extension of the science of living systems can be more effectively applied to some of our most vexing modern problems than the prevailing scheme, derived from abstractions in physics. While these have some universal application and demonstrate computational advantages, they are not theoretically mandated for the living. A new set of mathematical abstractions derived from biology can now be similarly extended. This is made possible by leveraging new formal tools to understand abstraction and enable computability. [The latter has a much expanded meaning in our context from the one known and used in computer science and biology today, that is "by rote algorithmic means", since it is not known if a living system is computable in this sense (Mossio et al., 2009).] Two major challenges constitute the effort. The first challenge is to design an original general system of abstractions within the biological domain. The initial issue is descriptive leading to the explanatory. There has not yet been a serious formal examination of the abstractions of the biological domain. What is used today is an amalgam; much is inherited from physics (via the bridging abstractions of chemistry) and there are many new abstractions from advances in mathematics (incentivized by the need for more capable computational analyses). Interspersed are abstractions, concepts and underlying assumptions “native” to biology and distinct from the mechanical language of physics and computation as we know them. A pressing agenda should be to single out the most concrete and at the same time the most fundamental process-units in biology and to recruit them into the descriptive domain. Therefore, the first challenge is to build a coherent formal system of abstractions and operations that is truly native to living systems. Nothing will be thrown away, but many common methods will be philosophically recast, just as in physics relativity subsumed and reinterpreted Newtonian mechanics. -/- This step is required because we need a comprehensible, formal system to apply in many domains. Emphasis should be placed on the distinction between multi-perspective analysis and synthesis and on what could be the basic terms or tools needed. The second challenge is relatively simple: the actual application of this set of biology-centric ways and means to cross-disciplinary problems. In its early stages, this will seem to be a “new science”. This White Paper sets out the case of continuing support of Information and Communication Technology (ICT) for transformative research in biology and information processing centered on paradigm changes in the epistemological, ontological, mathematical and computational bases of the science of living systems. Today, curiously, living systems cannot be said to be anything more than dissipative structures organized internally by genetic information. There is not anything substantially different from abiotic systems other than the empirical nature of their robustness. We believe that there are other new and unique properties and patterns comprehensible at this bio-logical level. The report lays out a fundamental set of approaches to articulate these properties and patterns, and is composed as follows. -/- Sections 1 through 4 (preamble, introduction, motivation and major biomathematical problems) are incipient. Section 5 describes the issues affecting Integral Biomathics and Section 6 -- the aspects of the Grand Challenge we face with this project. Section 7 contemplates the effort to formalize a General Theory of Living Systems (GTLS) from what we have today. The goal is to have a formal system, equivalent to that which exists in the physics community. Here we define how to perceive the role of time in biology. Section 8 describes the initial efforts to apply this general theory of living systems in many domains, with special emphasis on crossdisciplinary problems and multiple domains spanning both “hard” and “soft” sciences. The expected result is a coherent collection of integrated mathematical techniques. Section 9 discusses the first two test cases, project proposals, of our approach. They are designed to demonstrate the ability of our approach to address “wicked problems” which span across physics, chemistry, biology, societies and societal dynamics. The solutions require integrated measurable results at multiple levels known as “grand challenges” to existing methods. Finally, Section 10 adheres to an appeal for action, advocating the necessity for further long-term support of the INBIOSA program. -/- The report is concluded with preliminary non-exclusive list of challenging research themes to address, as well as required administrative actions. The efforts described in the ten sections of this White Paper will proceed concurrently. Collectively, they describe a program that can be managed and measured as it progresses. (shrink)

Twenty years ago I put a sign on the door to my office —and it’s still there— with the sentence of Peirce that I have used in my title: "The life of science is in the desire to learn" (CP 1.235, c.1902). I learned this quote from the late professor of logic at MIT, George Boolos. Like him, I put it on my door to invite students to come in to inquire, to ask questions, since their questions are not just (...) the life of science, but also the sparks that inflame my passion for teaching. Those —professors and students— who desire to learn are the real agents, the main characters, of philosophical development. Philosophy should not be understood and taught as the transmission of old solutions to outdated problems, but as a way of life devoted to learning the truth wherever we might find it. My exposition will be divided into four sections: 1) A brief presentation of Peirce, focusing on his work as a professional scientist and a scientific philosopher; 2) Peirce considered as an educational philosopher; 3) Some practical suggestions I have drawn from Peirce's ideas and from my experience teaching philosophy today; and finally, 4) A brief conclusion. (shrink)

All information results from a process, intrinsic to living beings, of info-autopoiesis or information self-production; a sensory commensurable, self-referential feedback process immanent to Bateson’s ‘difference which makes a difference’. To highlight and illustrate the fundamental nature of the info-autopoietic process, initially, two simulations based on one-parameter feedback are presented. The first, simulates a homeostatic control mechanism which is representative of a mechanistic, cybernetic system with very predictable dynamics, fully dependent on an external referent. The second, simulates a homeorhetic process, inherent (...) to biological systems, illustrating a self-referenced, autonomous system. Further, the active incorporation/interference of viral particles by prokaryotic cells and the activation of CRISPR-Cas can be understood as info-autopoiesis at the most fundamental cellular level, as well as constituting a planetary network of self-referenced information. Moreover, other examples of the info-autopoietic nature of information are presented to show the generality of its applicability. In short, info-autopoiesis is a recursive process that is sufficiently generic to be the only basis for information in nature: from the single cell, to multi-cellular organisms, to consideration of all types of natural and non-natural phenomena, including tools and artificial constructions. (shrink)

One usually makes assertions by means of uttering indicative sentences like “It is raining”. However, not every utterance of an indicative sentence is an assertion. For example, in uttering “I will be back tomorrow”, one might be making a promise. What is to make an assertion? C.S. Peirce held the view that “to assert a proposition is to make oneself responsible for its truth” (CP 5.543). In this thesis, I interpret Peirce’s view of assertion and I evaluate Peirce’s reasons for (...) holding it. I begin by reconstructing and assessing Peirce’s case for such view as it appears in (EP 2.140, 1903), (EP 2.312-313, 1904), and (CP 5.546, 1908). Then, I continue by elaborating on three aspects of Peirce’s view of assertion, namely, assertion as an act involving a certain kind of responsibility, the proposition as what is asserted, and responsibility for truth as a responsibility to give reasons. With respect to these three aspects, I argue for the following claims: (1) Peirce construed the responsibility involved in asserting as a moral responsibility; (2) Peirce held that propositions are types; and (3) Peirce was committed to a dialogical interpretation of “responsibility to give reasons”. Finally, I end by presenting two objections to Peirce’s view of assertion and its corresponding replies. I conclude that Peirce’s account of assertion is a valuable contribution to the philosophical debate on assertion. (shrink)