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James A. Anderson [20]James August Anderson [1]James A. D. W. Anderson [1]
  1.  35
    Are Phase 1 Trials Therapeutic? Risk, Ethics, and Division of Labor.James A. Anderson & Jonathan Kimmelman - 2014 - Bioethics 28 (3):138-146.
    Despite their crucial role in the translation of pre-clinical research into new clinical applications, phase 1 trials involving patients continue to prompt ethical debate. At the heart of the controversy is the question of whether risks of administering experimental drugs are therapeutically justified. We suggest that prior attempts to address this question have been muddled, in part because it cannot be answered adequately without first attending to the way labor is divided in managing risk in clinical trials. In what follows, (...)
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  2. Extending Clinical Equipoise to Phase 1 Trials Involving Patients: Unresolved Problems.A. Anderson James & Kimmelman Jonathan - 2010 - Kennedy Institute of Ethics Journal 20 (1):75-98.
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  3.  51
    The Ethics and Science of Placebo-Controlled Trials: Assay Sensitivity and the Duhem-Quine Thesis.James A. Anderson - 2006 - Journal of Medicine and Philosophy 31 (1):65 – 81.
    The principle of clinical equipoise requires that, aside from certain exceptional cases, second generation treatments ought to be tested against standard therapy. In violation of this principle, placebo-controlled trials (PCTs) continue to be used extensively in the development and licensure of second-generation treatments. This practice is typically justified by appeal to methodological arguments that purport to demonstrate that active-controlled trials (ACTs) are methodologically flawed. Foremost among these arguments is the so called assay sensitivity argument. In this paper, I take a (...)
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  4.  44
    The Research Subject as Wage Earner.James A. Anderson & Charles Weijer - 2002 - Theoretical Medicine and Bioethics 23 (4-5):359-376.
    The practice of paying research subjects for participating inclinical trials has yet to receive an adequate moral analysis.Dickert and Grady argue for a wage payment model in whichresearch subjects are paid an hourly wage based on that ofunskilled laborers. If we accept this approach, what follows?Norms for just working conditions emerge from workplacelegislation and political theory. All workers, includingpaid research subjects under Dickert and Grady''s analysis,have a right to at least minimum wage, a standard work week,extra pay for overtime hours, (...)
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  5.  9
    Managing Incidental Findings: Lessons From Neuroimaging.Emily Borgelt, James A. Anderson & Judy Illes - 2013 - American Journal of Bioethics 13 (2):46 - 47.
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  6.  65
    Contextualizing Clinical Research: The Epistemological Role of Clinical Equipoise.James A. Anderson - 2009 - Theoretical Medicine and Bioethics 30 (4):269-288.
    Since its introduction in 1987, Benjamin Freedman’s principle of clinical equipoise has enjoyed widespread uptake in bioethics discourse. Recent years, however, have witnessed a growing consensus that the principle is fundamentally flawed. One of the most vocal critics has undoubtedly been Franklin Miller. In a 2008 paper, Steven Joffe and Miller build on this critical work, offering a new conception of clinical research ethics based on science, taking what they call a “scientific orientation” toward the ethics of clinical research. Though (...)
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  7.  7
    The Ethics Wars: Disputes Over International Research.Charles Weijer & James A. Anderson - 2001 - Hastings Center Report 31 (3):18-20.
    The effort to revise the Declaration of Helsinki and the CIOMS Guidelines has sparked a sometimes vitriolic debate centering on the use of placebo controls.
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  8.  59
    Arithmetic on a Parallel Computer: Perception Versus Logic. [REVIEW]James A. Anderson - 2003 - Brain and Mind 4 (2):169-188.
    This article discusses the properties of a controllable, flexible, hybrid parallel computing architecture that potentially merges pattern recognition and arithmetic. Humans perform integer arithmetic in a fundamentally different way than logic-based computers. Even though the human approach to arithmetic is both slow and inaccurate it can have substantial advantages when useful approximations ( intuition ) are more valuable than high precision. Such a computational strategy may be particularly useful when computers based on nanocomponents become feasible because it offers a way (...)
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  9.  1
    Distinctive Features, Categorical Perception, and Probability Learning: Some Applications of a Neural Model.James A. Anderson, Jack W. Silverstein, Stephen A. Ritz & Randall S. Jones - 1977 - Psychological Review 84 (5):413-451.
  10.  5
    Transreal Newtonian Physics Operates at Singularities.James A. D. W. Anderson & Tiago Soares dos Reis - 2015 - Synesis 7 (2):57-81.
    Sir Isaac Newton, writing in Latin, defined his celebrated laws of motion verbally. When the laws of motion are read as relating to his arithmetic and his calculus, division by zero is undefined so his physics fails at mathematical singularities. The situation is unchanged in modern real arithmetic and real calculus: division by zero is undefined so both Newtonian Physics and its modern developments fail at mathematical singularities. However, when Newton’s text is read as relating to transreal arithmetic and transreal (...)
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  11.  7
    Review: On What Building a Martian Three-Wheeled Iguana Tells Us About Complex Minds. [REVIEW]James A. Anderson - 1991 - Behavior and Philosophy 19 (2):91 - 102.
  12.  1
    An Ecology of Communication: An Acknowledgement of Gregory Bateson.James A. Anderson - 2003 - American Journal of Semiotics 19 (1/4):35-67.
    Written from a post-modern perspective, this article makes use of the concepts of obligation, subject position, line of action, discursive form, sentient agent, exchange, mediating technology, intentionality, improvisational performance, and communicative routines to produce an overarching theory of communication and its processes. The work of the article is to develop the linkages among these concepts and founds this analysis in ethnographic research. It concludes that the process of communication occurs inside a nexus of obligation from relational subject positions within some (...)
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  13.  12
    Turing's Test and the Perils of Psychohistory.James A. Anderson - 1994 - Social Epistemology 8 (4):327 – 332.
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  14.  2
    A Theory for the Recognition of Items From Short Memorized Lists.James A. Anderson - 1973 - Psychological Review 80 (6):417-438.
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  15.  12
    The Challenges of Collaborative Knowledge.James A. Anderson - unknown
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  16.  9
    A Critical Appraisal of Protections for Aboriginal Communities in Biomedical Research.Charles Weijer & James A. Anderson - unknown
    As scientists target communities for research into the etiology, especially the genetic determinants of common diseases, there have been calls for the protection of communities. This paper identifies the distinct characteristics of aboriginal communities and their implications for research in these communities. It also contends that the framework in the Belmont Report is inadequate in this context and suggests a fourth principle of respect for communities. To explore how such a principle might be specified and operationalized, it reviews existing guidelines (...)
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  17.  4
    The Research Subject as Entrepreneur.James A. Anderson & Charles Weijer - 2001 - American Journal of Bioethics 1 (2):67-69.
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  18.  1
    Predictive Genomic Testing of Children for Adult Onset Disorders: A Canadian Perspective.Michael J. Szego, M. Stephen Meyn, James A. Anderson, Robin Hayeems, Cheryl Shuman, Nasim Monfared, Sarah Bowdin & Randi Zlotnik Shaul - 2014 - American Journal of Bioethics 14 (3):19-21.
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  19.  1
    Matters of Life and Death: Making Moral Theory Work in Medical Ethics and the Law.James A. Anderson & Charles Weijer - unknown
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  20. Ethics and Culture of an Organization.James A. Anderson & Elaine E. Englehardt - 2007 - Teaching Ethics 7 (2):39-48.
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  21. Reply to Grossberg.James A. Anderson & Jack W. Silverstein - 1978 - Psychological Review 85 (6):597-603.
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