Historian James H. Jones published the first edition of Bad Blood, the definitive history of the Tuskegee Syphilis Experiment, in 1981. Its clear-eyed examination of that research and its implications remains a bioethics classic, and the 30-year anniversary of its publication served as the impetus for the reexamination of research ethics that this symposium presents. Recent revelations about the United States Public Health Service study that infected mental patients and prisoners in Guatemala with syphilis in the late 1940s in (...) order to determine the efficacy of treatment represent only one of the many attestations to the persistence of ongoing, critical, and underaddressed issues in research ethics that Bad Blood first explored. Those issues include, but are not limited to: the complex and contested matters of the value of a given research question, the validity of the clinical trial designed to address it, and the priorities of science. (shrink)

Perhaps no technological innovation has so dominated the second half of the twentieth century as has the introduction of the programmable computer. It is quite difficult if not impossible to imagine how contemporary affairs—in business and science, communications and transportation, governmental and military activities, for example—could be conducted without the use of computing machines, whose principal contribution has been to relieve us of the necessity for certain kinds of mental exertion. The computer revolution has reduced our mental labors by means (...) of these machines, just as the Industrial Revolution reduced our physical labor by means of other machines. (shrink)

This book demonstrates instead the writers' use of irony and allegory in struggling against the deceitfulness of their own texts.

1. WHAT IS ARTIFICIAL INTELLIGENCE? One of the fascinating aspects of the field of artificial intelligence (AI) is that the precise nature of its subject ..

The book uses Zen Buddhism as the opening wedge for an extraordinarily wide-ranging exploration of consciousness.

This sequel to the widely read Zen and the Brain continues James Austin's explorations into the key interrelationships between Zen Buddhism and brain research. In Zen-Brain Reflections, Austin, a clinical neurologist, researcher, and Zen practitioner, examines the evolving psychological processes and brain changes associated with the path of long-range meditative training. Austin draws not only on the latest neuroscience research and new neuroimaging studies but also on Zen literature and his personal experience with alternate states of consciousness.Zen-Brain Reflections takes (...) up where the earlier book left off. It addresses such questions as: how do placebos and acupuncture change the brain? Can neuroimaging studies localize the sites where our notions of self arise? How can the latest brain imaging methods monitor meditators more effectively? How do long years of meditative training plus brief enlightened states produce pivotal transformations in the physiology of the brain? In many chapters testable hypotheses suggest ways to correlate normal brain functions and meditative training with the phenomena of extraordinary states of consciousness.After briefly introducing the topic of Zen and describing recent research into meditation, Austin reviews the latest studies on the amygdala, frontotemporal interactions, and paralimbic extensions of the limbic system. He then explores different states of consciousness, both the early superficial absorptions and the later, major "peak experiences." This discussion begins with the states called kensho and satori and includes a fresh analysis of their several different expressions of "oneness." He points beyond the still more advanced states toward that rare ongoing stage of enlightenment that is manifest as "sage wisdom."Finally, with reference to a delayed "moonlight" phase of kensho, Austin envisions novel links between migraines and metaphors, moonlight and mysticism. The Zen perspective on the self and consciousness is an ancient one. Readers will discover how relevant Zen is to the neurosciences, and how each field can illuminate the other. (shrink)

The purpose of this paper is to explore three alternative frameworks for understanding the nature of language and mentality, which accent syntactical, semantical, and pragmatical aspects of the phenomena with which they are concerned, respectively. Although the computational conception currently exerts considerable appeal, its defensibility appears to hinge upon an extremely implausible theory of the relation of form to content. Similarly, while the representational approach has much to recommend it, its range is essentially restricted to those units of language that (...) can be understood in terms of undefined units. Thus, the only alternative among these three that can account for the meaning of primitive units of language is one emphasizing the basic role of skills, habits, and tendencies in relating signs and dispositions. (shrink)

This sequel to the widely read Zen and the Brain continues James Austin's explorations into the key interrelationships between Zen Buddhism and brain research. In Zen-Brain Reflections, Austin, a clinical neurologist, researcher, and Zen practitioner, examines the evolving psychological processes and brain changes associated with the path of long-range meditative training. Austin draws not only on the latest neuroscience research and new neuroimaging studies but also on Zen literature and his personal experience with alternate states of consciousness.Zen-Brain Reflections takes (...) up where the earlier book left off. It addresses such questions as: how do placebos and acupuncture change the brain? Can neuroimaging studies localize the sites where our notions of self arise? How can the latest brain imaging methods monitor meditators more effectively? How do long years of meditative training plus brief enlightened states produce pivotal transformations in the physiology of the brain? In many chapters testable hypotheses suggest ways to correlate normal brain functions and meditative training with the phenomena of extraordinary states of consciousness.After briefly introducing the topic of Zen and describing recent research into meditation, Austin reviews the latest studies on the amygdala, frontotemporal interactions, and paralimbic extensions of the limbic system. He then explores different states of consciousness, both the early superficial absorptions and the later, major "peak experiences." This discussion begins with the states called kensho and satori and includes a fresh analysis of their several different expressions of "oneness." He points beyond the still more advanced states toward that rare ongoing stage of enlightenment that is manifest as "sage wisdom."Finally, with reference to a delayed "moonlight" phase of kensho, Austin envisions novel links between migraines and metaphors, moonlight and mysticism. The Zen perspective on the self and consciousness is an ancient one. Readers will discover how relevant Zen is to the neurosciences, and how each field can illuminate the other. (shrink)

James H. Donelan describes how two poets, a philosopher, and a composer - Hölderlin, Wordsworth, Hegel, and Beethoven - developed an idea of self-consciousness based on music at the turn of the nineteenth century. This idea became an enduring cultural belief: the understanding of music as an ideal representation of the autonomous creative mind. Against a background of political and cultural upheaval, these four major figures - all born in 1770 - developed this idea in both metaphorical and actual (...) musical structures, thereby establishing both the theory and the practice of asserting self-identity in music. Beethoven still carries the image of the heroic composer today; this book describes how it originated in both his music and in how others responded to him. Bringing together the fields of philosophy, musicology, and literary criticism, Donelan shows how this development emerged from the complex changes in European cultural life taking place between 1795 and 1831. (shrink)

The notion of program verification appears to trade upon an equivocation. Algorithms, as logical structures, are appropriate subjects for deductive verification. Programs, as causal models of those structures, are not. The success of program verification as a generally applicable and completely reliable method for guaranteeing program performance is not even a theoretical possibility.

It has been remarked that there is a tendency in all Governments to an augmentation of power at the expense of liberty. But the remark as usually understood does not appear to me well founded.... It is a melancholy reflection that liberty should be equally exposed to danger whether the Government have too much or too little power, and that the line which divides the extremes should be so inaccurately drawn by experience. -/- Madison, letter to Jefferson, October 17, 1788.

Being able to ask others to do things, and thereby giving them reasons to do those things, is a prominent feature of our interpersonal lives. In this paper, I discuss the distinctive normative status of requests – what makes them different from commands and demands. I argue for a theory of this normative phenomenon which explains the sense in which the reasons presented in requests are a matter of discretion. This discretionary quality, I argue, is something that other theories cannot (...) accommodate, though it is a significant aspect of the relations that people stand in to one another, and the kinds of practical reasons that flow from those relations. (shrink)

A personal story of the ways in which persistence, chance, and creativity interact in biomedical research. This first book by the author of Zen and the Brain examines the role of chance in the creative process. James Austin tells a personal story of the ways in which persistence, chance, and creativity interact in biomedical research; the conclusions he reaches shed light on the creative process in any field. Austin shows how, in his own investigations, unpredictable events shaped the outcome (...) of his research and brought about novel results. He then goes beyond this story of serendipity to propose a new classification of the varieties of chance, drawing on his own research and examples from the history of science—including the famous accidents that led Fleming to the discovery of penicillin. Finally, he explores the nature of the creative process, considering not only the environmental and neurophysiological correlates of creativity but also the role of intuition in both scientific discoveries and spiritual quests. This updated MIT Press paperback edition includes a new introduction and recent material on medical research, creativity, and spirituality. (shrink)

Collective memory can make and break political culture around the world. Representations and reinterpretations of the past intersect with actions that shape the future. A nation's political culture emerges from complex layers of institutional and individual responses to historical events. Society changes and is changed by these layers of memory over time. Understanding them gives us insight into where we are today. Encompassing examples from colonization and decolonization, revolving around the critical junctures of the world wars, this book illustrates how (...) collective memory is produced and organized, through commemoration, through monuments, and through individuals sharing stories. Using concrete examples from around the world, James H. Liu shows how different disciplines can come together through shared concepts like narratives and generational memories to provide mutually enriching perspectives on how political culture is made, and how it changes. (shrink)

Based on the Zen philosophy about focusing away from the self, a guide to "neural Zen" meditative practices draws on recent findings in brain research to outline recommendations for various methods of pursuing a balanced, selfless state of ...

The purpose of this paper is to provide a systematic defense of the single-case propensity account of probabilistic explanation from the criticisms advanced by Hanna and by Humphreys and to offer a critical appraisal of the aleatory conception advanced by Humphreys and of the deductive-nomological-probabilistic approach Railton has proposed. The principal conclusion supported by this analysis is that the Requirements of Maximal Specificity and of Strict Maximal Specificity afford the foundation for completely objective explanations of probabilistic explananda, so long as (...) they are employed on the basis of propensity criteria of explanatory relevance. (shrink)

The ethical philosophy of Emmanuel Levinas is typically associated with a punishing conception of responsibility rather than freedom. In this chapter, our aim is to explore Levinas’s often overlooked theory of freedom. Specifically, we compare Levinas’s account of freedom to the Kantian (and Fichtean) idea of freedom as autonomy and the Hegelian idea of freedom as relational. Based on these comparisons, we suggest that Levinas offers a distinctive conception of freedom—“finite freedom.” In contrast to Kantian autonomy, finite freedom constitutively involves (...) standing in certain social relations with others. And in contrast to Hegelian relational freedom, the social relations involved in finite freedom are not defined by mutual recognition, but by feelings of separation and even antagonism. Along the way, we promote a reading Levinas’s Totality and Infinity as a Hegel-style story of Bildung (development), and show how, on Levinas’s view, freedom can develop or mature in the life of the individual. (shrink)

On some accounts, early reflection on the nature of human cognition focused on its physical or physiological causes (as, for example, when in fragment 105 Empedocles identifies thought with blood). On other accounts, there was an identifiable process of semantic development in which a number of perception-oriented terms for knowing (e.g. gignôskô, oida, noeô, and suniêmi) took on a more intellectual orientation. Although some find evidence of this transition in the poems of Solon and Archilochus, appreciation for a distinction between (...) sensing and knowing is more plausibly credited to the Presocratic thinkers Heraclitus and Parmenides. It is unclear whether Heraclitus regarded sense perception as an essential first stage in acquiring knowledge (or an inherently inferior form of awareness), but the goddess in Parmenides’ poem unambiguously urges the youth to whom she speaks to set aside the testimony of eye and ear and instead ‘judge by reason’ the nature of what-is. (shrink)

We need to clarify at least four aspects of selfhood if we are to reach a better understanding of consciousness in general, and of its alternate states. First, how did we develop our self-centred psychophysiology? Second, can the four familiar lobes of the brain alone serve, if only as preliminary landmarks of convenience, to help understand the functions of our many self-referent networks? Third, what could cause one's former sense of self to vanish from the mental field during an extraordinary (...) state of consciousness? Fourth, when a person's physical and psychic self do drop off briefly, how has conscious experience then been transformed? In particular, what happens to that subject's personal sense of time? Our many-sided self arose in widely distributed brain networks. Since infancy, these self-oriented circuits have been over-conditioned by limbic biases. Selfhood then seems to have evolved along lines suggesting at least in shorthand the operations of a kind of ‘I-Me-Mine’ complex. But what happens when this egocentric triad briefly dissolves? Novel states of consciousness emerge. Two personally-observed states are discussed: insight-wisdom ; internal absorption. How do these two states differ phenomenologically? The physiological processes briefly suggested here emphasize shifts in deeper systems, and pivotal roles for thalamo-cortical interactions in the front and back of the brain. (shrink)

In his Symposium, Plato crafted speeches in praise of love that has influenced writers and artists from antiquity to the present. But questions remain concerning the meaning of specific features, the significance of the dialogue as a whole, and the character of its influence. Here, an international team of scholars addresses such questions.

This cutting edge volume provides an overview of the dynamic new field of cyberphilosophy – the intersection of philosophy and computing.

This is not the usual kind of self-help book. Indeed, its major premise heeds a Zen master's advice to be _less_ self-centered. Yes, it is "one more book of words about Zen," as the author concedes, yet this book explains meditative practices from the perspective of a " _neural_ Zen." The latest findings in brain research inform its suggestions. In _Meditating Selflessly_, James Austin -- Zen practitioner, neurologist, and author of three acclaimed books on Zen and neuroscience -- guides (...) readers toward that open awareness already awaiting them on the cushion and in the natural world. Austin offers concrete advice -- often in a simplified question-and-answer format -- about different ways to meditate. He clarifies both the concentrative and receptive styles of meditation. Drawing widely from the exciting new field of contemplative neuroscience, Austin helps resolve an ancient paradox: why both insight wisdom _and_ selflessness arise simultaneously during enlightened states of consciousness. (shrink)

Carl G. Hempel exerted greater influence upon philosophers of science than any other figure during the 20th century. In this far-reaching collection, distinguished philosophers contribute valuable studies that illuminate and clarify the central problems to which Hempel was devoted. The essays enhance our understanding of the development of logical empiricism as the major intellectual influence for scientifically-oriented philosophers and philosophically-minded scientists of the 20th century.

Parmenides may fairly be said to have undertaken two parallel efforts: first, to offer a persuasive account of the nature of ‘what-is’ (to eon); and second, to establish ‘it is’ as the only true and trustworthy way of speaking and thinking about what-is. Fragment 7.3-6 plays a crucial role in this latter effort when Parmenides’ goddess directs the youth to put aside all information obtained through sense perception and instead ‘judge by reason the poludêris elenchos spoken by me.’ Although the (...) meaning of the phrase has been variously understood, I argue that it is properly taken to mean ‘a much-contested testing’ (of the possible ways of inquiry). In characterizing the elenchos as poludêris or ‘much contested’ the goddess is asserting that the decision to follow the ‘it is’ route of inquiry must be continually reaffirmed against the pull of custom and sense experience. (shrink)

If the decades of the forties through the sixties were dominated by discussion of Hempel's “covering law“ explication of explanation, that of the seventies was preoccupied with Salmon's “statistical relevance” conception, which emerged as the principal alternative to Hempel's enormously influential account. Readers of Wesley C. Salmon's Scientific Explanation and the Causal Structure of the World, therefore, ought to find it refreshing to discover that its author has not remained content with a facile defense of his previous investigations; on the (...) contrary, Salmon offers an original account of different kinds of explications, advances additional criticisms of various alternative theories, and elaborates a novel “two-tiered“ analysis of explanation that tacitly depends upon a “two-tiered” account of homogeneity. Indeed, if the considerations that follow are correct, Salmon has not merely refined his statistical relevance account but has actually abandoned it in favor of a “causal/mechanistic“ construction. This striking development suggests that the theory of explanation is likely to remain as lively an arena of debate in the eighties as it has been in the past. (shrink)

Introduction: and a pop quiz -- Administrative ethics: ideas, sources, and development -- Refining the sense of duty: responsibilities of public administrators and the issue of agency -- Reinforcing and enlarging duty: philosophical bases of ethical behavior and the ethics triangle -- Codifying duty and ethical perspectives: professional codes of ethics -- Undermining duty: challenges to the ethical behavior of public administrators -- Deciding how to meet obligations and act responsibly: ethical analysis and problem solving -- Acting on duty in (...) the face of uncertainty and risk: responsible whistleblowing -- Elevating ethical behavior in the organization -- Mandating duty: external measures to promote ethics -- Conclusion: the duties of public administrators. (shrink)