Results for 'Jeron Bruggeman'

15 found
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  1.  59
    Biocomplexity: A Pluralist Research Strategy is Necessary for a Mechanistic Explanation of the "Live" State.F. J. Bruggeman, H. V. Westerhoff & F. C. Boogerd - 2002 - Philosophical Psychology 15 (4):411 – 440.
    The biological sciences study (bio)complex living systems. Research directed at the mechanistic explanation of the "live" state truly requires a pluralist research program, i.e. BioComplexity research. The program should apply multiple intra-level and inter-level theories and methodologies. We substantiate this thesis with analysis of BioComplexity: metabolic and modular control analysis of metabolic pathways, emergence of oscillations, and the analysis of the functioning of glycolysis.
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  2. Emergence and Its Place in Nature: A Case Study of Biochemical Networks.F. C. Boogerd, F. J. Bruggeman, Robert C. Richardson, Achim Stephan & H. Westerhoff - 2005 - Synthese 145 (1):131 - 164.
    We will show that there is a strong form of emergence in cell biology. Beginning with C.D. Broad's classic discussion of emergence, we distinguish two conditions sufficient for emergence. Emergence in biology must be compatible with the thought that all explanations of systemic properties are mechanistic explanations and with their sufficiency. Explanations of systemic properties are always in terms of the properties of the parts within the system. Nonetheless, systemic properties can still be emergent. If the properties of the components (...)
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  3.  28
    Emergence and its Place in Nature: A Case Study of Biochemical Networks.Fred C. Boogerd, Frank J. Bruggeman, Robert C. Richardson, Achim Stephan & Hans V. Westerhoff - 2005 - Synthese 145 (1):131-164.
    We will show that there is a strong form of emergence in cell biology. Beginning with C.D. Broad’s classic discussion of emergence, we distinguish two conditions sufficient for emergence. Emergence in biology must be compatible with the thought that all explanations of systemic properties are mechanistic explanations and with their sufficiency. Explanations of systemic properties are always in terms of the properties of the parts within the system. Nonetheless, systemic properties can still be emergent. If the properties of the components (...)
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  4.  22
    Systems Biology: At Last an Integrative Wet and Dry Biology.Frank J. Bruggeman - 2007 - Biological Theory 2 (2):183-188.
    The progress of the molecular biosciences has been so enormous that a discipline studying how cellular functioning emerges out of the behaviors of their molecular constituents has become reality. Systems biology studies cells as spatiotemporal networks of interacting molecules using an integrative approach of theory , experimental biology , and quantitative network-wide analytical measurement . Its aim is to understand how molecules jointly bring about life. Systems biology is rapidly discovering principles governing the functioning of molecular networks and methods to (...)
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  5.  67
    Systems Biology: Philosophical Foundations.Fred C. Boogerd, Frank J. Bruggeman, Jan-Hendrik S. Hofmeyr & Hans V. Westerhoff (eds.) - 2007 - Elsevier.
    Systems biology is a vigorous and expanding discipline, in many ways a successor to genomics and perhaps unprecendented in its combination of biology with a ...
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  6.  38
    Towards Philosophical Foundations of Systems Biology: Introduction.Fred C. Boogerd, Frank J. Bruggeman, Jan-Hendrik S. Hofmeyr & Hans V. Westerhoff - 2007 - In Fred C. Boogerd, Frank J. Bruggeman, Jan-Hendrik S. Hofmeyr & Hans V. Westerhoff (eds.), Systems Biology: Philosophical Foundations. Elsevier.
  7.  11
    Tijd AlS Omsluiting, Tijd AlS Ontsluiting.Atie Th Brüggeman-Kruyff - 1982 - Philosophia Reformata 47 (1):41-68.
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  8.  4
    Multi-Tasking of Biosynthetic and Energetic Functions of Glycolysis Explained by Supply and Demand Logic.Johan H. van Heerden, Frank J. Bruggeman & Bas Teusink - 2015 - Bioessays 37 (1):34-45.
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  9.  20
    Afterthoughts as Foundations for Systems Biology.Fred C. Boogerd, Frank J. Bruggeman, Jan-Hendrik S. Hofmeyr & Hans V. Westerhoff - 2007 - In Fred C. Boogerd, Frank J. Bruggeman, Jan-Hendrik S. Hofmeyr & Hans V. Westerhoff (eds.), Systems Biology: Philosophical Foundations. Elsevier.
  10.  82
    Inter-Level Relations in Computer Science, Biology, and Psychology.Fred Boogerd, Frank Bruggeman, Catholijn Jonker, Huib Looren de Jong, Allard Tamminga, Jan Treur, Hans Westerhoff & Wouter Wijngaards - 2002 - Philosophical Psychology 15 (4):463–471.
    Investigations into inter-level relations in computer science, biology and psychology call for an *empirical* turn in the philosophy of mind. Rather than concentrate on *a priori* discussions of inter-level relations between 'completed' sciences, a case is made for the actual study of the way inter-level relations grow out of the developing sciences. Thus, philosophical inquiries will be made more relevant to the sciences, and, more importantly, philosophical accounts of inter-level relations will be testable by confronting them with what really happens (...)
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  11. Casper J. Albers, Barteld P. Kooi and Willem Schaafsma/Trying to Resolve the Two-Envelope Problem Edwin H.-C. Hung/Projective Explanation: How Theories Explain Empirical Data in Spite of Theory. [REVIEW]Fc Boogerd, Fj Bruggeman & Rc Richardson - 2005 - Synthese 145 (1):499-500.
     
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  12.  67
    Mechanistic Explanations and Models in Molecular Systems Biology.Fred C. Boogerd, Frank J. Bruggeman & Robert C. Richardson - 2013 - Foundations of Science 18 (4):725-744.
    Mechanistic models in molecular systems biology are generally mathematical models of the action of networks of biochemical reactions, involving metabolism, signal transduction, and/or gene expression. They can be either simulated numerically or analyzed analytically. Systems biology integrates quantitative molecular data acquisition with mathematical models to design new experiments, discriminate between alternative mechanisms and explain the molecular basis of cellular properties. At the heart of this approach are mechanistic models of molecular networks. We focus on the articulation and development of mechanistic (...)
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  13.  23
    Abstraction and the Language Familiarity Effect.Elizabeth K. Johnson, Laurence Bruggeman & Anne Cutler - 2018 - Cognitive Science 42 (2):633-645.
    Talkers are recognized more accurately if they are speaking the listeners’ native language rather than an unfamiliar language. This “language familiarity effect” has been shown not to depend upon comprehension and must instead involve language sound patterns. We further examine the level of sound-pattern processing involved, by comparing talker recognition in foreign languages versus two varieties of English, by English speakers of one variety, English speakers of the other variety, and non-native listeners. All listener groups performed better with native than (...)
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  14.  43
    Toward a Philosophy of Systems Biology: Systems Biology: Philosophical Foundations, Fred C. Boogerd , Frank J. Bruggeman , Jan-Hendrik S. Hofmeyr , and Hans V. Westerhoff , Eds. Amsterdam: Elsevier, 2007, (360 Pp; €99.95 Hbk; ISBN 978-0-444-52085-2).Jonathan F. Davies & Maureen A. O'Malley - 2007 - Biological Theory 2 (4):420-422.
  15.  19
    Neural Correlates of Reward Processing in Healthy Siblings of Patients with Schizophrenia.Esther Hanssen, Jorien van der Velde, Paula M. Gromann, Sukhi S. Shergill, Lieuwe de Haan, Richard Bruggeman, Lydia Krabbendam, André Aleman & Nienke van Atteveldt - 2015 - Frontiers in Human Neuroscience 9.