13 found
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John Appleby [7]John B. Appleby [4]John H. Appleby [2]
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John Appleby
University of Warwick (PhD)
John Appleby
King's College London
  1.  9
    Mitochondrial Replacement: Ethics and Identity.Anthony Wrigley, Stephen Wilkinson & John B. Appleby - 2015 - Bioethics 29 (9):631-638.
    Mitochondrial replacement techniques have the potential to allow prospective parents who are at risk of passing on debilitating or even life-threatening mitochondrial disorders to have healthy children to whom they are genetically related. Ethical concerns have however been raised about these techniques. This article focuses on one aspect of the ethical debate, the question of whether there is any moral difference between the two types of MRT proposed: Pronuclear Transfer and Maternal Spindle Transfer. It examines how questions of identity impact (...)
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  2.  68
    The Ethical Challenges of the Clinical Introduction of Mitochondrial Replacement Techniques.John B. Appleby - 2015 - Medicine, Health Care and Philosophy 18 (4):501-514.
    Mitochondrial DNA (mtDNA) diseases are a group of neuromuscular diseases that often cause suffering and premature death. New mitochondrial replacement techniques (MRTs) may offer women with mtDNA diseases the opportunity to have healthy offspring to whom they are genetically related. MRTs will likely be ready to license for clinical use in the near future and a discussion of the ethics of the clinical introduction ofMRTs is needed. This paper begins by evaluating three concerns about the safety of MRTs for clinical (...)
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  3. Creatures of the Nihil.John Appleby - 2001 - Pli 11:270-277.
    Keith Ansell Pearson and Diane Morgan , Nihilism Now! Monsters of Energy ISBN - 9780333732922Gary Banham and Charlie Blake , Evil Spirits: Nihilism and the Fate of Modernity ISBN - 9780719056420.
     
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  4. Schizoanalysis and Empiricism.John Appleby - 2000 - Pli 9:239-247.
    Eugene W. Holland, Deleuze and Guattari’s Anti-Oedipus:Introduction to Schizoanalysis ISBN - 9780415113182Patrick Hayden, Multiplicity and Becoming: The Pluralist Empiricismof Gilles Deleuze, Studies in European Thought XV ISBN - 9780820438566.
     
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  5.  37
    An Odd Couple.John Appleby - 2011 - The Philosophers' Magazine 52 (52):109-110.
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  6.  34
    Speculating Against Belief.John Appleby - 2008 - The Philosophers' Magazine 43:119-120.
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  7. Facing the Swarm: Encountering a Non-Human War Machine.John Appleby - 1998 - Pli 7:143-154.
     
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  8.  1
    Should Mitochondrial Donation Be Anonymous?John B. Appleby - 2018 - Journal of Medicine and Philosophy: A Forum for Bioethics and Philosophy of Medicine 43 (2):261-280.
    Currently in the United Kingdom, anyone donating gametes has the status of an open-identity donor. This means that, at the age of 18, persons conceived with gametes donated since April 1, 2005 have a right to access certain pieces of identifying information about their donor. However, in early 2015, the UK Parliament approved new regulations that make mitochondrial donors anonymous. Both mitochondrial donation and gamete donation are similar in the basic sense that they involve the contribution of gamete materials to (...)
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  9.  9
    Erasmus King: Eighteenth-Century Experimental Philosopher.John H. Appleby - 1990 - Annals of Science 47 (4):375-392.
    Well-known in his day, but overlooked since, Erasmus King lectured in natural and experimental philosophy from the 1730s until 1756 at his Westminster home and twenty other venues, publicizing his frequent courses exclusively in the Daily Advertiser. In 1739 he escorted Desaguliers's youngest son to Russia, hoping to demonstrate experimental philosophy to the Russian empress. En route, he conducted trials with a sea-guage in the Baltic which were reported by Stephen Hales in his Statical Essays. Various sources testify to King's (...)
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  10.  2
    The Ethics of Mitochondrial Replacement.John B. Appleby, Rosamund Scott & Stephen Wilkinson - 2017 - Bioethics 31 (1):2-6.
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  11.  4
    A New Perspective on John Rowley, Virtuoso Master of Mechanics and Hydraulic Engineer.John H. Appleby - 1996 - Annals of Science 53 (1):1-27.
    Although best known as a scientific instrument maker, John Rowley extended his sphere of activity very considerably as Master of Mechanics to George I and as a hydraulic engineer at the Offices of Ordnance and Works. Re-examined and untapped sources provide fresh evidence of these aspects of his work and highlight his predilection for the arts and the virtuosity of his artefacts. The findings also have implications for studies of the instrument-making trade in the early eighteenth century.
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  12.  1
    An Odd Couple. [REVIEW]John Appleby - 2011 - The Philosophers' Magazine 52:109-110.
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  13. Speculating Against Belief. [REVIEW]John Appleby - 2008 - The Philosophers' Magazine 43:119-120.
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