Estimates of the burden of disease assess the mortality and morbidity that affect a population by producing summary measures of health such as quality-adjusted life years and disability-adjusted life years. These measures typically do not include stillbirths among the negative health outcomes they count. Priority-setting decisions that rely on these measures are therefore likely to place little value on preventing the more than three million stillbirths that occur annually worldwide. In contrast, neonatal deaths, which occur in comparable numbers, have a (...) substantial impact on burden of disease estimates and are commonly seen as a pressing health concern. In this article we argue in favor of incorporating unintended fetal deaths that occur late in pregnancy into estimates of the burden of disease. Our argument is based on the similarity between late-term fetuses and newborn infants and the assumption that protecting newborns is important. We respond to four objections to counting stillbirths: that fetuses are not yet part of the population and so their deaths should not be included in measures of population health; that valuing the prevention of stillbirths will undermine women's reproductive rights; that including stillbirths implies that miscarriages should also be included; and that birth itself is in fact ethically significant. We conclude that our proposal is ethically preferable to current practice and, if adopted, is likely to lead to improved decisions about health spending. (shrink)

How far does a researcher’s responsibility extend when an incidental finding is identified? Balancing pertinent ethical principles such as beneficence, respect for persons, and duty to rescue is not always straightforward, particularly in neuroimaging research where empirical data that might help guide decision making are lacking. We conducted a systematic survey of perceptions and preferences of 396 investigators, research participants, and Institutional Review Board members at our institution. Using the partial entrustment model as described by Richardson, we argue that our (...) data supports universal reading by a neuroradiologist of all research MRI scans for incidental findings and providing full disclosure to all participants. (shrink)

This book examines Proclus' doctrine of evil in light of the tradition of exegesis of Plato's treatment of evil within the schools of ancient Platonism, from ...

This study reconsiders Denis O'Brien's controversial thesis that it was Plotinus' position that the 'partial' soul generates matter. O'Brien relies principally on two core texts, 3.4 .1 and 3.9 .3, where he finds convincing evidence for his thesis. In the present study I take two approaches. First, I demonstrate that if we accept O'Brien's thesis, then we are compelled to accept as well that Plotinus is guilty of self-contradiction in his doctrine of soul's descent. Secondly, I offer a different interpretation (...) of what Plotinus has in mind as the source of matter's generation in 3.4.1 and 3.9.3. In several passages Plotinus states that the product of the partial soul's creative activity is the "trace" of soul that, in turn, combines with matter to form the 'qualified body.' I argue that it is this trace-soul, not matter, that Plotinus is referring to in these texts. (shrink)

BackgroundReturning neuroimaging incidental findings may create a challenge to research participants’ health literacy skills as they must interpret and make appropriate healthcare decisions based on complex radiology jargon. Disclosing IF can therefore present difficulties for participants, research institutions and the healthcare system. The purpose of this study was to identify the extent of the health literacy challenges encountered when returning neuroimaging IF. We report on findings from a retrospective survey and focus group sessions with major stakeholders involved in disclosing IF.MethodsWe (...) surveyed participants who had received a radiology report from a research study and conducted focus groups with participants, parents of child participants, Institutional Review Board members, investigators and physicians. Qualitative thematic analyses were conducted using standard group-coding procedures and descriptive summaries of health literacy scores and radiology report outcomes are examined.ResultsAlthough participants reported high health literacy skills, 67 % did not seek medical care when recommended to do so; and many participants in the focus groups disclosed they could not understand the findings described in their report. Despite their lack of understanding, participants desire to have information about their radiology results, and the investigators feel ethically inclined to return findings.ConclusionsThe language in clinically useful radiology reports can create a challenge for participants’ health literacy skills and has the potential to negatively impact the healthcare system and investigators conducting imaging research. Radiology reports need accompanying resources that explain findings in lay language, which can help reduce the challenge caused by the need to communicate incidental findings. (shrink)

In this interview Samuel Weber proposes a rethinking of the relation of secrecy to transparency and outlines some of the forms it takes, while considering certain of its implications for current social, political and epistemological contexts. He begins by questioning the opposition itself, suggesting that we will have to learn to be more at home with the secret and that the demand for transparency must be radically rethought and complicated. He argues that the demand for absolute transparency can only promote (...) and obscure the process by which the ‘secret’ is placed in the service of private appropriation. As the emotional experience of the relation between transparency and secrecy reflects the historically specific traditions that constitute the sense of self, then it is that sense that should be ‘opened up to its irreducible heterogeneity’. (shrink)

We generalize an observation made by Goldblatt in "Diodorean modality in Minkowski spacetime" by proving that each -dimensional integral spacetime frame equipped with Robb's irreflexive `after' relation determines a unique temporal logic. Our main result is that, unlike -dimensional spacetime where, as Goldblatt has shown, the Diodorean modal logic is the same for each frame , in the case of -dimensional integral spacetime, the frame determines a unique Diodorean modal logic.

We consider the problem of axiomatizing various natural "successor" logics for 2-dimensional integral spacetime. We provide axiomatizations in monomodal and multimodal languages, and prove completeness theorems. We also establish that the irreflexive successor logic in the "standard" modal language (i.e. the language containing □ and ◊) is not finitely axiomatizable.

This article, which introduces the special section on The Urban Problematic, takes as its starting point the ways in which categories associated with the ‘urban’ have broken down, such that the once singular and coherent concept ‘city’ has disintegrated in certain ways: the notion has been demythologized, so that representations of the city must now be regarded as partial and invested; and cities themselves have become opaque and unpredictable both to urban scholars and to governments, planners and various kinds of (...) welfare organizations. The indications of crisis, captured for instance by concerns about the slums, favelas and shanty towns of the world’s megacities, also indicate that much of what counts in modern urban life is in some way connected with the marginal, the unofficial, and the supplemental. The article takes a supplemental view of the current state of urban dwelling. This involves at the same time a longer, more patient, historical view in its attempt to understand the current state of the city as part of a shift in the play of heterogeneous forces. With reference to the articles contained in The Urban Problematic, this introductory article finally draws attention to some of the urgent and critical issues of contemporary urbanism. (shrink)

For more than 30 years and until his death in 2004 Jacques Derrida remained one of the most influential contemporary philosophers. It may be difficult to evaluate what forms his heritage will take in the future but _Derrida Now_ provides some provocative suggestions. Derrida’s often-controversial early reception was based on readings of his complex works, published in journals and collected in books. More recently attention has tended to focus on his later work, which grew out of the seminars that he (...) presented each year in France and the US. The full texts of these seminars are now the subject of a major publication project, to be produced over the next ten years. _Derrida Now_ presents contemporary articles based on or around the study of Derrida. It provides a critical introduction to Derrida’s complex and controversial thought, offers careful analysis of some of his most important concepts, and includes essays that address the major strands of his thought. Derrida’s influence reached not only into philosophy but also into other fields concerned with literature, politics, visual art, law, ecology, psychoanalysis, gender and sexuality and this book will appeal to readers in all these disciplines. Contributors include Peggy Kamuf, Geoff Bennington, Sarah Wood, Roy Sellars, Graham Allen, and Irving Goh. (shrink)

Neoplatonic Exegeses of Plato's Cosmogony JOHN F. PHILLIPS AMONG THE MANY CONTROVERSIES to which the long history of interpretation of Plato's Timaeus has given rise, that concerning the eternity of the cosmos is one of the most enduring and complex, and the source of almost continuous debate from the time of Xenocrates to the present. The importance to all Platonists of a doctrinally consistent answer to the question of whether or not the universe had a beginning in time is made (...) amply clear in the statement attributed to Iamblichus by Proclus that proper understand- ing of the creation of the world is crucial for the entire theory of Nature. Iamblichus here refers obliquely to the orthodox Platonist position that the universe is not a temporal being subject to decay and destruction. The princi- pal problem for all of them, of course, was that, taken literally, Plato's account of the creation in the Timaeus, particularly the passage 27C-a8C, appears to be an unequivocal affirmation of a temporal beginning to the cosmos. Espe- cially troublesome was Plato's use of the verb y~yovev in Timaeus 28b 7, which seems to be an explicit claim for an &QX1] in time. That this passage did indeed refer to a temporal beginning was a point that was made repeatedly and forcefully by the chief opponents of the Platonists on this issue, the Peripa- tetics, who, following Aristotle, read the Timaeus creation account literally.' To.. (shrink)

The main project of this dissertation is to analyze various temporal conceptions of modality for discrete n-dimensional spacetime. The first chapter contains an introduction to the problem and known results. Chapter 2 consists of a study of logics which are analogues of the so-called 'logic of today and tomorrow' and 'logic of tomorrow' investigated by Segerberg and others. We consider the analogues of these successor logics for 2-dimensional integral spacetime. We provide axiomatizations in monomodal and multimodal languages and prove completeness (...) theorems. We also establish that the irreflexive successor logic in the "standard" modal language is not finitely axiomatizable. ;Chapter 3 investigates the axiomatization problem for 2-dimensional integral spacetime frames with Robb's irreflexive 'after' relation. We provide an axiomatization in a multimodal language and prove that this axiomatization is complete. We use this result to prove the system in the "standard" modal language is decidable. ;In Chapter 4 we take up the problem of what the correct Diodorean modal logic is for 2-dimensional integral spacetime. We show that the corresponding Diodorean modal logic is not S4.2, nor indeed any known modal system. We then present several candidate axioms and prove their independence in the context of S4.2. We also study some of the sublogics of the Diodorean modal logic for 2-dimensional discrete spacetime . ;The final chapter contains some general results. First we prove that for every n ≥ 2 the n-dimensional frame determines a unique Diodorean modal logic. We also consider temporal logics in the language with F and P for two kinds of irreflexive spacetime frames. We prove that for every n ≥ 2 the n-dimensional frame with Robb's 'after' relation determines a unique temporal logic. We also prove a generalized completeness theorem for n-dimensional irreflexive successor logics. Finally, in an appendix, we provide a list of selected open problems and indicate directions for future research in this area. (shrink)

Kleinian psychoanalysis has recently experienced a renaissance in academic and clinical circles. _Reading Melanie Klein_ responds to the upsurge of interest in her work by bringing together the most innovative and challenging essays on Kleinian thought from the last two decades. The book features material which appears here for the first time in English, and several newly written chapters. _Reading Melaine Klein_ recontextualizes Klein to the more well-known works of Freud and Lacan and disproves the long-held claim that her psychoanalysis (...) is both too normative and too conservative for critical consideration. The essays address Klein's distinctive readings of the unconscious and phantasy, her tenacious commitment to the death drive, her fecund notions of anxiety, projection and projective identification and, most famously, her challenge to Freud's Oedipus complex and theories of sexual difference. The authors demonstrate that not only is it possible to rethink the epistemological basis of Kleinian theory, rendering it as vital as those of Freud and Lacan, but also that her psychoanalysis can engage in powerful and productive dialogue with diverse disciplines such as politics, ethics and literary theory. This timely collection is an invaluable addition to the scholarship on Melaine Kein and catalyst for further debate not only within the psychoanalytic community but also across social, critical and cultural studies. (shrink)

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Nothing survives deconstruction unless we accept that survival in some sense attaches to the ghostly or etiolated figures (the marks and traces) of things, by which deconstruction proceeds. If the ghostly figure survives then it may be because it is undeconstructible. Yet the spectral figure would no doubt remain insignificant if it was not for the force it brings to bear on more central and familiar categories of philosophical and literary discourse. These categories, like style, friendship, justice and hospitality, tend (...) to occupy those spectral spaces that mark the structural difference between philosophy (conceptual, abstract, universal) and literature (figurative, concrete, singular). Yet nothing defines such spaces so well as the trace and its paradoxical structure. And nothing describes the structure of the trace so well as that of the signature. This paper identifies the movement of the trace as occupying and to a great extent defining the difference between philosophy and literature. The example, in this case, is the appearance of asphodels in Homer's Odyssey, according to which the fields where ghosts live are thick with the so-called grave-flower. But the asphodel on closer examination breaks down into mere traces of itself in a series of insoluble philological problems. The larger implications have to do with death, the signature of the writer, the relation between philosophy and literature and their respective modes of survival. There is no philosophy (no truth, no good, no chance) without its attachment to the etiolated figure, the trace of itself. The paper proposes readings of Blanchot, Derrida, Hegel and Plato, in addition to a focus on the main philological problem in Homer and its implications for a tradition of literary allusion, as a way of establishing the consistency of the paradoxical structure of the signature. (shrink)

This accessible and wide-ranging introduction to critical theory provides a comprehensive overview of the practice, role, and importance of theory across the humanities and social sciences. It not only maps a notoriously complex area, but it also enables the reader to take the arguments and apply them in practice. Starting with an explanation of how theory relies on implicit assumptions that inform interpretations, the book moves on to depict the long-term philosophical problems that have fed into much 20th century thinking (...) and also more recent debates. The philosophical grounds of contemporary thought are traced from Plato through Descartes to the work of Heidegger and Freud and on to recent developments in structuralism and deconstruction that critically revise many of the previous terms of debate. (shrink)

For more than 30 years and until his death in 2004 Jacques Derrida remained one of the most influential contemporary philosophers. It may be difficult to evaluate what forms his heritage will take in the future but _Derrida Now_ provides some provocative suggestions. Derrida’s often-controversial early reception was based on readings of his complex works, published in journals and collected in books. More recently attention has tended to focus on his later work, which grew out of the seminars that he (...) presented each year in France and the US. The full texts of these seminars are now the subject of a major publication project, to be produced over the next ten years. _Derrida Now_ presents contemporary articles based on or around the study of Derrida. It provides a critical introduction to Derrida’s complex and controversial thought, offers careful analysis of some of his most important concepts, and includes essays that address the major strands of his thought. Derrida’s influence reached not only into philosophy but also into other fields concerned with literature, politics, visual art, law, ecology, psychoanalysis, gender and sexuality and this book will appeal to readers in all these disciplines. Contributors include Peggy Kamuf, Geoff Bennington, Sarah Wood, Roy Sellars, Graham Allen, and Irving Goh. (shrink)

This article examines Plato's claim that the founders of the ideal city ought to establish a law compelling the philosophers to rule. This claim is perplexing as it seems to suggest that in the ideal city justice is not in the best interests of its possessor, for by obeying the law and ruling the philosopher will in turn be made very unhappy. Following a critical appraisal and ultimate rejection of a number of different attempts to make sense of this tension, (...) this article advances a 'communitarian' interpretation. According to this interpretation, the existence of a law compelling the philosopher to rule is ultimately in her best interest because her ruling will lead to a well-educated and intellectually virtuous community. The existence of this virtuous community will, in turn, allow the philosopher better to achieve her principal goal -- the attainment and preservation of truth. (shrink)

Breaking new ground in Sarraute studies, John Phillips reads the novels and plays of Nathalie Sarraute in a hitherto largely neglected critical perspective. Through a detailed analysis of textual metaphors, he demonstrates that Sarraute's writing is informed and inspired by an intensely personal set of desires. Unlike previous criticism, which has stressed the formal aspects of the writing to the exclusion of the psychological, this study exploits contemporary psychoanalytic and feminist theory to expose an unconscious feminine dimension which the author (...) herself has never recognized. (shrink)

This Very Short Introduction aims to disentangle the 'real' Marquis de Sade from his mythical and demonic reputation of the past two hundred years. Phillips examines Sade's life and work: his libertine novels, his championing of atheism, and his uniqueness in bringing the body and sex back into philosophy.

What has been learned about logic by means of "uninterpreted" logistic systems can be supplemented by comparing the latter with systems which are more uninterpreted, as well as with others which are less uninterpreted than the well-known logistic systems. By somewhat extending the meaning of 'uninterpreted', I hope to establish certain claims about the nature of logistic systems and also to cast some light on the nature of "logic itself." My procedure involves looking at three major "degrees" of interpretation: first, (...) systems uninterpreted both semantically and syntactically, second, systems uninterpreted semantically but not syntactically, and third, systems uninterpreted neither semantically nor syntactically. We shall be forced to limit ourselves to the truth-functional part of logic in this brief study. What are usually called uninterpreted systems can be seen on a continuum of "degrees" of interpretation, from ordinary reasoning at one extreme to a "thoroughly uninterpreted system" at the other. "Logic itself" apparently lies nearer to the interpreted, deformalized end of the spectrum than to the uninterpreted, formalized end. Logic is not identical with any particular logistic system, but is that which the particular logistic systems aim to formalize or model or capture. I propose that it is that minimum set of logical, rather than syntactical, primitive terms, definitions, and rules which is needed to generate logically, rather than syntactically, the principles of ordinary reasoning as it is used by logicians in their metalinguistic discussions and informal proofs of metatheorems. This minimum set is somewhat larger than the primitive bases of most logistic systems; its truth-functional part is presented in the "Deformalized Logic" at degree twelve. (shrink)

Taking the publication in English of several works by Alain Badiou and Jacques Rancière as its point of departure, this review article attempts to outline what may be at stake in reading these two authors together. Looking especially at the works on politics and on aesthetics, the article also draws on other major texts by these authors as a way of clarifying their basic philosophical principles. Under the rubrics of ‘the axiom of equality’ and ‘the empty set’, these two thinkers (...) establish links with their tradition in ways that are mobilized towards invention or transfiguration in spheres of both politics and art. (shrink)

Recent arguments asserting a topological turn in culture also identify a range of topologically informed interventions in social and cultural theory. Talk of a topological turn evokes both the enduring interest that the field of mathematics presents and the business of analysis in the cultural sphere. This article questions the novelty of this ‘becoming topological of culture’ and digs into a deeper historicity in order to identify the trends that may be said to support the development of topology in the (...) current situation. It also examines the relationship between mathematics considered ontologically and mathematics considered epistemologically, in order to better grasp the significance of the practical abstractions that mathematics as technics manifests. Discussions of Cantor, Russell, Poincaré, Lévi-Strauss, Lacan and others address the background of contemporary mathematical topology. The article goes on to examine Alain Badiou’s principle that mathematics is ontology and concludes with a discussion of the mathematics of Martin Heidegger. (shrink)

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Some modifications are suggested to recent (1985) generalised phrase-structure grammar which make the formalism more suitable to computational use, and at the same time provide a clear and elegant redefinition for parts of the formalism which are standardly complex and ill-defined. It is shown how the feature-instantiation principles can be represented as explicit rules in a format similar to metarules, and how a grammar of four parts, immediate-dominance rules, linear-precedence rules, metarules, and these new propagation rules, can be used to (...) produce the ordinary GPSG analyses of English. Methods of computational implementation are discussed, in particular it is suggested that the parts of the grammar are most conveniently interpreted as instructions as to how to produce a set of context-free phrase-structure rules which can be used with a simple left-corner parser. (shrink)