19 found
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  1. Delusion, Rationality, Empathy: Commentary on Martin Davies Et Al.Gregory Currie & Jon Jureidini - 2001 - Philosophy, Psychiatry, and Psychology 8 (2):159-162.
  2.  97
    Narrative and Coherence.Gregory Currie & Jon Jureidini - 2004 - Mind and Language 19 (4):409–427.
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  3. Clinical Trials and Drug Promotion.Jon Jureidini, Leemon McHenry & Peter Mansfield - 2008 - International Journal of Risk and Safety in Medicine 20:73-81.
    Selective reporting is prevalent in the medical literature, particularly in industry-sponsored research. In this paper, we expose selective reporting that is not evident without access to internal company documents. The published report of study 329 of paroxetine in adolescents sponsored by GlaxoSmithKline claims that “paroxetine is generally well tolerated and effective for major depression in adolescents”. By contrast, documents obtained during litigation reveal that study 329 was negative for efficacy on all 8 protocol specified outcomes and positive for harm.
     
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  4. The Citalopram CIT-MD-18 Pediatric Depression Trial: A Deconstruction of Medical Ghostwriting, Data Manipulation and Academic Malfeasance.Leemon McHenry, Jon Jureidini & Jay Amsterdam - 2016 - International Journal of Risk and Safety in Medicine 28:33-43.
    This paper is a deconstruction of a ghostwritten report of a randomized, double-blind, placebo-controlled efficacy and safety trial of citalopram in depressed children and adolescents conducted in the United States. Court documents revealed that protocol-specified outcome measures showed no statistically significant difference between citalopram and placebo. However, the published article concluded that citalopram was safe and significantly more efficacious than placebo for children and adolescents, with possible adverse effects on patient safety.
     
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  5. Industry-Sponsored Ghostwriting in Clinical Trial Reporting: A Case Study.Leemon McHenry & Jon Jureidini - 2008 - Accountability in Research 15 (3):152-167.
    In this case study from litigation, we show how ghostwriting of clinical trial results can contribute to the manipulation of data to favor the study medication. Study 329 for paroxetine pediatric use was negative for efficacy and positive for harm. Yet the ghostwritten publication from this study concluded that paroxetine provided evidence of efficacy and safety and continues to be influential. Despite the role of named authors in revisions of the manuscript, the sponsor company remained in control of the message.
     
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  6.  47
    Art and Delusion.Jon Jureidini - 2003 - The Monist 86 (4):556-578.
  7.  67
    Dispensing with the Dynamic Unconscious.Gerard O'Brien & Jon Jureidini - 2002 - Philosophy, Psychiatry, and Psychology 9 (2):141-153.
    In recent years, a number of contemporary proponents of psychoanalysis have sought to derive support for their conjectures about the _dynamic_ unconscious from the empirical evidence in favor of the _cognitive_ unconscious. It is our contention, however, that far from supporting the dynamic unconscious, recent work in cognitive science suggests that the time has come to dispense with this concept altogether. In this paper we defend this claim in two ways. First, we argue that any attempt to shore up the (...)
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  8. Book Review: Pilar Ordóñez-López and Nuria Edo-Marzá (Eds), Medical Discourse in Professional, Academic and Popular Settings. [REVIEW]Jon Jureidini - 2018 - Discourse Studies 20 (2):313-314.
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  9. Disease-Mongering: A Response.Jon Jureidini - 2014 - Monash Bioethics Review 25 (3):24-25.
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  10. Key Opinion Leaders and Pediatric Antidepressant Overprescribing.Jon Jureidini & Leemon McHenry - 2009 - Psychotherapy and Psychosomatics 78:197-201.
    The lingering controversy concerning the usefulness and safety of antidepressants for children and adolescents is likely to confuse clinicians. Recent papers perpetuate the claim that antidepressants are shown to be safe and effective in randomised controlled trials. Others claim that antidepressants have been shown to prevent suicides. In this editorial we address the manipulation of outcomes that result from academics’ alliance with industry. We explain how industry and key opinion leaders have distorted the clinician’s perception of the safety and usefulness (...)
     
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  11. An Enemy of the Open Society.Leemon McHenry & Jon Jureidini - 2020 - Institute of Art and Ideas.
    Corporate interests corrupt clinical trials, physicians and universities, undermining the foundation of evidence-based medicine. Philosopher Leemon McHenry and psychiatrist Jon Jureidini argue that the principles underlying Popper’s philosophy of science can protect clinical research from corporate malfeasance in a capitalist economy. -/- Evidence-based medicine was a paradigm shift that is often praised as one of the greatest achievements of medicine in the twentieth century. This radical change in medical practice is based on epistemological hierarchies of evidence, from opinions of respected (...)
     
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  12. Conflicted Medical Journals and the Failure of Trust.Leemon McHenry & Jon Jureidini - 2011 - Accountability in Research 18:45-54.
    Journals are failing in their obligation to ensure that research is fairly represented to their readers, and must act decisively to retract fraudulent publications. Recent case reports have exposed how marketing objectives usurped scientific testing and compromised the credibility of academic medicine. But scant attention has been given to the role that journals play in this process, especially when evidence of research fraud fails to elicit corrective measures. Our experience with The Journal of the American Academy of Child and Adolescent (...)
     
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  13. Industry-Corrupted Psychiatric Trials.Leemon McHenry, Jon Jureidini & Jay Amsterdam - 2017 - Psychiatria Polska 51 (6):993-1008.
    The goal of this paper is to expose the research misconduct of pharmaceutical industry-sponsored clinical trials via three short case studies of corrupted psychiatric trials that were conducted in the United States. We discuss the common elements that enable the misrepresentation of clinical trial results including ghostwriting for medical journals, the role of key opinion leaders as co-conspirators with the pharmaceutical industry and the complicity of top medical journals in failing to uphold standards of science and peer review. We conclude (...)
     
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  14. On the Proposed Changes to the Credibility Gap in Industry-Supported Biomedical Research: A Critical Evaluation.Leemon McHenry & Jon Jureidini - 2012 - Ethical Human Psychology and Psychiatry 14 (3):156-161.
    A task force of pharmaceutical industry employees and medical journal editors propose ten recommendations to address the problem of erosion of confidence in reporting industry-sponsored clinical trial results. These recommendations do not solve the fundamental problem of industry-sponsored biomedical research. A radical solution is required that severs the relationship between the industry and the journals and restores the integrity of the medical literature.
     
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  15. Privatization of Knowledge and the Creation of Biomedical Conflicts of Interest.Leemon Mchenry & Jon Jureidini - 2009 - Journal of Ethics in Mental Health 1 (4):1-6.
    Scientific and ethical misconduct has increased at an alarming rate as a result of the privatization of knowledge. What began as an effort to stimulate entrepreneurship and increase discovery in biomedical research by strengthening the ties between industry and academics has led to an erosion of confidence in the reporting of research results. Inherent tensions between profit-directed inquiry and knowledge-directed inquiry are instantiated in psychopharmacology, especially in the co-option of academic activity to corporate objectives. The effects of these tensions are (...)
     
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  16.  46
    The Illusion of Evidence-Based Medicine: Exposing the Crisis of Credibility in Clinical Research.Leemon McHenry & Jon Jureidini - 2020 - Adelaide SA, Australia: Wakefield Press.
    We live in an age alleged devoted to evidence-based medicine. Evidence-based medicine, however, depends on reliable data and if the data are largely, if not completely, manipulated by the manufacturer of pharmaceuticals, then the data are not reliable. Evidence-based medicine is an illusion. This book raises and attempts to answer the following questions: What are the ways in which the profit motive of industry undermines the integrity of science? How is science protected from corporate malfeasance in a capitalist economy? Our (...)
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  17. The Illusion of Evidence Based Medicine.Leemon McHenry & Jon Jureidini - 2022 - British Medical Journal 8 (376):702-703.
    The advent of evidence-based medicine was a paradigm shift intended to provide a solid scientific foundation for medicine. The validity of this paradigm, however, depends on reliable data from clinical trials, mostly conducted by the pharmaceutical industry and reported in the names of senior academics. The release of previously confidential pharmaceutical industry documents into the public domain has given the medical community valuable insight into the degree to which industry-sponsored clinical trials are manipulated and misrepresented. Until this problem is corrected, (...)
     
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  18.  37
    Response.Jon Jureidini - 2006 - Journal of Bioethical Inquiry 3 (3):195-196.
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  19.  28
    The Last Rites of the Dynamic Unconscious.Gerard O'Brien & Jon Jureidini - 2002 - Philosophy, Psychiatry, and Psychology 9 (2):161-166.
    © 2003 by The Johns Hopkins University Press.
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