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  1. The Citalopram CIT-MD-18 Pediatric Depression Trial: A Deconstruction of Medical Ghostwriting, Data Manipulation and Academic Malfeasance.Leemon McHenry, Jon Jureidini & Jay Amsterdam - 2016 - International Journal of Risk and Safety in Medicine 28:33-43.
    This paper is a deconstruction of a ghostwritten report of a randomized, double-blind, placebo-controlled efficacy and safety trial of citalopram in depressed children and adolescents conducted in the United States. Court documents revealed that protocol-specified outcome measures showed no statistically significant difference between citalopram and placebo. However, the published article concluded that citalopram was safe and significantly more efficacious than placebo for children and adolescents, with possible adverse effects on patient safety.
     
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  2. Delusion, Rationality, Empathy.Gregory Currie & Jon Jureidini - 2001 - Philosophy, Psychiatry, and Psychology 8 (2-3):159-62.
  3. Clinical Trials and Drug Promotion.Jon Jureidini, Leemon McHenry & Peter Mansfield - 2008 - International Journal of Risk and Safety in Medicine 20:73-81.
    Selective reporting is prevalent in the medical literature, particularly in industry-sponsored research. In this paper, we expose selective reporting that is not evident without access to internal company documents. The published report of study 329 of paroxetine in adolescents sponsored by GlaxoSmithKline claims that “paroxetine is generally well tolerated and effective for major depression in adolescents”. By contrast, documents obtained during litigation reveal that study 329 was negative for efficacy on all 8 protocol specified outcomes and positive for harm.
     
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  4. Delusion, Rationality, Empathy: Commentary on Martin Davies Et Al.Gregory Currie & Jon Jureidini - 2001 - Philosophy, Psychiatry, and Psychology 8 (2):159-162.
  5. Industry-Sponsored Ghostwriting in Clinical Trial Reporting: A Case Study.Leemon McHenry & Jon Jureidini - 2008 - Accountability in Research 15 (3):152-167.
    In this case study from litigation, we show how ghostwriting of clinical trial results can contribute to the manipulation of data to favor the study medication. Study 329 for paroxetine pediatric use was negative for efficacy and positive for harm. Yet the ghostwritten publication from this study concluded that paroxetine provided evidence of efficacy and safety and continues to be influential. Despite the role of named authors in revisions of the manuscript, the sponsor company remained in control of the message.
     
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  6.  84
    Narrative and Coherence.Gregory Currie & Jon Jureidini - 2004 - Mind and Language 19 (4):409–427.
  7.  37
    Art and Delusion.Jon Jureidini - 2003 - The Monist 86 (4):556-578.
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  8.  63
    Dispensing with the Dynamic Unconscious.Gerard O'Brien & Jon Jureidini - 2002 - Philosophy, Psychiatry, and Psychology 9 (2):141-153.
    In recent years, a number of contemporary proponents of psychoanalysis have sought to derive support for their conjectures about the _dynamic_ unconscious from the empirical evidence in favor of the _cognitive_ unconscious. It is our contention, however, that far from supporting the dynamic unconscious, recent work in cognitive science suggests that the time has come to dispense with this concept altogether. In this paper we defend this claim in two ways. First, we argue that any attempt to shore up the (...)
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  9.  29
    Response.Jon Jureidini - 2006 - Journal of Bioethical Inquiry 3 (3):195-196.
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  10.  17
    The Last Rites of the Dynamic Unconscious.Gerard O'Brien & Jon Jureidini - 2002 - Philosophy, Psychiatry, and Psychology 9 (2):161-166.
    © 2003 by The Johns Hopkins University Press.
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  11. Key Opinion Leaders and Pediatric Antidepressant Overprescribing.Jon Jureidini & Leemon McHenry - 2009 - Psychotherapy and Psychosomatics 78:197-201.
    The lingering controversy concerning the usefulness and safety of antidepressants for children and adolescents is likely to confuse clinicians. Recent papers perpetuate the claim that antidepressants are shown to be safe and effective in randomised controlled trials. Others claim that antidepressants have been shown to prevent suicides. In this editorial we address the manipulation of outcomes that result from academics’ alliance with industry. We explain how industry and key opinion leaders have distorted the clinician’s perception of the safety and usefulness (...)
     
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  12. Conflicted Medical Journals and the Failure of Trust.Leemon McHenry & Jon Jureidini - 2011 - Accountability in Research 18:45-54.
    Journals are failing in their obligation to ensure that research is fairly represented to their readers, and must act decisively to retract fraudulent publications. Recent case reports have exposed how marketing objectives usurped scientific testing and compromised the credibility of academic medicine. But scant attention has been given to the role that journals play in this process, especially when evidence of research fraud fails to elicit corrective measures. Our experience with The Journal of the American Academy of Child and Adolescent (...)
     
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  13. Industry-Corrupted Psychiatric Trials.Leemon McHenry, Jon Jureidini & Jay Amsterdam - 2017 - Psychiatria Polska 51 (6):993-1008.
    The goal of this paper is to expose the research misconduct of pharmaceutical industry-sponsored clinical trials via three short case studies of corrupted psychiatric trials that were conducted in the United States. We discuss the common elements that enable the misrepresentation of clinical trial results including ghostwriting for medical journals, the role of key opinion leaders as co-conspirators with the pharmaceutical industry and the complicity of top medical journals in failing to uphold standards of science and peer review. We conclude (...)
     
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  14. On the Proposed Changes to the Credibility Gap in Industry-Supported Biomedical Research: A Critical Evaluation.Leemon McHenry & Jon Jureidini - 2012 - Ethical Human Psychology and Psychiatry 14 (3):156-161.
    A task force of pharmaceutical industry employees and medical journal editors propose ten recommendations to address the problem of erosion of confidence in reporting industry-sponsored clinical trial results. These recommendations do not solve the fundamental problem of industry-sponsored biomedical research. A radical solution is required that severs the relationship between the industry and the journals and restores the integrity of the medical literature.
     
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  15. Privatization of Knowledge and the Creation of Biomedical Conflicts of Interest.Leemon Mchenry & Jon Jureidini - 2009 - Journal of Ethics in Mental Health 1 (4):1-6.
    Scientific and ethical misconduct has increased at an alarming rate as a result of the privatization of knowledge. What began as an effort to stimulate entrepreneurship and increase discovery in biomedical research by strengthening the ties between industry and academics has led to an erosion of confidence in the reporting of research results. Inherent tensions between profit-directed inquiry and knowledge-directed inquiry are instantiated in psychopharmacology, especially in the co-option of academic activity to corporate objectives. The effects of these tensions are (...)
     
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