24 found
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  1.  56
    Can aging research generate a theory of health?Jonathan Sholl - 2021 - History and Philosophy of the Life Sciences 43 (2):1-26.
    While aging research and policy aim to promote ‘health’ at all ages, there remains no convincing explanation of what this ‘health’ is. In this paper, I investigate whether we can find, implicit within the sciences of aging, a way to know what health is and how to measure it, i.e. a theory of health. To answer this, I start from scientific descriptions of aging and its modulators and then try to develop some generalizations about ‘health’ implicit within this research. After (...)
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  2. Putting phenomenology in its place: some limits of a phenomenology of medicine.Jonathan Sholl - 2015 - Theoretical Medicine and Bioethics 36 (6):391-410.
    Several philosophers have recently argued that phenomenology is well-suited to help understand the concepts of health, disease, and illness. The general claim is that by better analysing how illness appears to or is experienced by ill individuals—incorporating the first-person perspective—some limitations of what is seen as the currently dominant third-person or ‘naturalistic’ approaches to understand health and disease can be overcome. In this article, after discussing some of the main insights and benefits of the phenomenological approach, I develop three general (...)
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  3.  19
    Redrawing therapeutic boundaries: microbiota and cancer.Jonathan Sholl, Gregory Sepich-Poore, Rob Knight & Thomas Pradeu - 2022 - Trends in Cancer 8 (2):87-97.
    The unexpected roles of the microbiota in cancer challenge explanations of carcinogenesis that focus on tumor-intrinsic properties. Most tumors contain bacteria and viruses, and the host’s proximal and distal microbiota influence both cancer incidence and therapeutic responsiveness. Continuing the history of cancer–microbe research, these findings raise a key question: to what extent is the microbiota relevant for clinical oncology? We approach this by critically evaluating three issues: how the microbiota provides a predictive biomarker of cancer growth and therapeutic responsiveness, the (...)
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  4.  40
    Everything in moderation or moderating everything? Nutrient balancing in the context of evolution and cancer metabolism.Jonathan Sholl - 2022 - Biology and Philosophy 37 (2):1-32.
    While philosophers of science have marginally discussed concepts such as ‘nutrient’, ‘naturalness’, ‘food’, or the ‘molecularization’ of nutrition, they have yet to seriously engage with the nutrition sciences. In this paper, I offer one way to begin this engagement by investigating conceptual challenges facing the burgeoning field of nutritional ecology and the question of how organisms construct a ‘balanced’ diet. To provide clarity, I propose the distinction between nutrient balance as a property of foods or dietary patterns and nutrient balancing (...)
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  5. Taking a Naturalistic Turn in the Health and Disease Debate.Jonathan Sholl & Simon Okholm - 2021 - Teorema: International Journal of Philosophy (1):91-109.
    We situate the well-trodden debate about defining health and disease within the project of a metaphysics of science and its aim to work with and contribute to science. We make use of Guay and Pradeu’s ‘metaphysical box’ to reframe this debate, showing what is at stake in recent attempts to move beyond it, revealing unforeseen points of agreement and disagreement among new and old positions, and producing new questions that may lead to progress. We then discuss the implications of the (...)
     
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  6.  18
    Contextualizing Medical Norms: Georges Canguilhem's Surnaturalism.Jonathan Sholl - 2016 - In Élodie Giroux (ed.), Naturalism in Philosophy of Health: Issues and Implications. Cham: Springer. pp. 81-100.
    One of the key criticisms of understanding health in terms of adaptation to one’s environment is that medical judgments should be able to apply across environments. If we say that a condition is pathological ‘for person X in environment E’, then we quickly run into problems of desirability and social values. However, many key concepts in biology entail an inability to separate the organism from its environment. In other words, it is precisely by referring to ‘organism X in environment E’ (...)
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  7.  72
    The muddle of medicalization: pathologizing or medicalizing?Jonathan Sholl - 2017 - Theoretical Medicine and Bioethics 38 (4):265-278.
    Medicalization appears to be an issue that is both ubiquitous and unquestionably problematic as it seems to signal at once a social and existential threat. This perception of medicalization, however, is nothing new. Since the first main writings in the 1960s and 1970s, it has consistently been used to describe inappropriate or abusive instances of medical authority. Yet, while this standard approach claims that medicalization is a growing problem, it assumes that there is simply one “medical model” and that the (...)
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  8.  34
    Escaping the Conceptual Analysis Straightjacket: Pathological Mechanisms and Canguilhem’s Biological Philosophy.Jonathan Sholl - 2015 - Perspectives in Biology and Medicine 58 (4):395-418.
    This essay discusses four key criticisms recently leveled against the main attempts to use conceptual analysis to understand health and disease. First, it examines the weaknesses of these attempts and suggests a better way to proceed. Next, it briefly discusses another disease debate concerning pathological mechanisms and suggests that this approach could be more fruitful than that of conceptual analysis. The final section demonstrates how Georges Canguilhem's biological philosophy of disease avoids some of the problems associated with conceptual analysis, and (...)
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  9.  8
    How is ‘Health’ Explained Across the Sciences? Conclusions and Recapitulation.Jonathan Sholl & Suresh Rattan - 2020 - In Jonathan Sholl & Suresh I. S. Rattan (eds.), Explaining Health Across the Sciences. Springer Nature. pp. 541-549.
    In this concluding chapter, we gather the various contributions of this volume and attempt to extract some of the many key insights and challenges raised when it comes to the project of explaining health across the sciences. These insights were distilled down into a selection of the central concepts and issues defended or discussed by the authors, and were organized into a table to see, at a glance, where the attention was given. Reflecting on these insights will go some way (...)
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  10.  9
    The Sciences of Healthy Aging Await a Theory of Health.Jonathan Sholl - 2020 - Biogerontology 21 (3):399-409.
    Debates in fields studying the biological aspects of aging and longevity, such as biogerontology, are often split between ‘anti-aging’ approaches aimed largely at treating diseases and those focusing more on maintaining, promoting, and even enhancing health. However, it is far from clear what this ‘health’ is that would be maintained, promoted, or enhanced. Interestingly, what few have yet to fully reflect on is that there is still no theory of health within the health or aging sciences that would provide an (...)
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  11.  11
    Biomarkers of Health and Healthy Ageing from the Outside-In.Jonathan Sholl & Suresh Rattan - 2019 - In Alexey Moskalev (ed.), Biomarkers of Human Aging. Springer. pp. 37-46.
    Understanding the phenomenon of health is crucial for ageing research since there is often an implicit view on what constitutes health and how to measure it. We provide some reflections on how we might better understand and measure health, discuss the basic biological principles of survival, ageing, age-related diseases and eventual death, and end by tying these ideas together to rethink the nature of and implications for healthy ageing. We defend a more positive view on health understood in terms of (...)
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  12.  60
    The Knowledge of Life in Canguilhem's Critical Naturalism.Jonathan Sholl - 2012 - Pli 23:107-127.
  13.  17
    Vital Norms: Canguilhem’s The Normal and the Pathological in the Twenty-First Century.Pierre-Olivier Méthot & Jonathan Sholl (eds.) - 2020 - Paris: Hermann.
  14.  46
    Who’s afraid of nutritionism?Jonathan Sholl & David Raubenheimer - forthcoming - British Journal for the Philosophy of Science.
    Various scientists and philosophers have heavily criticized what they see as problematic forms of ‘nutritional reductionism’ or ‘nutritionism’ whereby studying food–health interactions at the level of isolated food components produces largely misguided science and misleading interpretations. However, the exact target of these diverse criticisms remains elusive, and its implications are overstated, which may hinder scientific understanding. To better identify the types of flaws supposedly hindering reductionist research, we disentangle three types of reductionist claims to better determine what the debate is (...)
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  15.  12
    Health in Philosophy: Definitions Abound but a Theory Awaits.Jonathan Sholl - 2020 - In Jonathan Sholl & Suresh I. S. Rattan (eds.), Explaining Health Across the Sciences. Springer Nature. pp. 79-95.
    Philosophers of medicine have long debated the possibility of a/the definition of health, but they have yet to fully reflect on the intriguing observation that there is still no theory of health within the medical sciences similar to general theories in other sciences. In this chapter, I provide some reasons for why this lack persists and why philosophers have not been particularly helpful or even interested in filling it. After clarifying why such a theory could be useful, I discuss five (...)
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  16. Plastic, Variable, and Constructive: Renewing Canguilhem’s Biological Normativity.Jonathan Sholl - 2020 - In Pierre-Olivier Méthot & Jonathan Sholl (eds.), Vital Norms: Canguilhem’s The Normal and the Pathological in the Twenty-First Century. Paris: Hermann. pp. 255-294.
  17.  5
    The vices and virtues of medical models of obesity.Jonathan Sholl & Andreas De Block - forthcoming - Obesity Reviews.
    Despite numerous public health organizations supporting the pathologization of obesity and considering recent obesity rates a health crisis, many researchers in the humanities, social sciences, and even in the health sciences remain unconvinced. In this paper, we address a set of arguments coming from these academic fields that criticize medical models of obesity for their supposedly flawed diagnostic categories that shift focus onto individuals and support moralizing judgements. Clarifying some key claims in these models and explicating the view of obesity (...)
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  18.  13
    Towards a Critique of Normalization: Canguilhem and Boorse.Jonathan Sholl & Andreas Block - 2015 - In Darian Meacham (ed.), Medicine and Society, New Perspectives in Continental Philosophy. Dordrecht: Springer Verlag. pp. 141 - 158.
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  19.  24
    Evolution and Normativity.Jonathan Sholl - 2014 - Dissertation, Ku Leuven
    Defining the concepts of health and disease has proved rather difficult and many philosophers of medicine have simply concluded that we would be better off giving up on such endeavors. I feel that this view is misguided mainly because it seems to rest on a rather inadequate understanding of how philosophers use biology to clarify medical concepts. While some philosophers appeal to biology so as to clarify what we mean by the concepts of health and disease, others attempt to use (...)
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  20.  11
    Reframing nutritional microbiota studies to reflect an inherent metabolic flexibility of the human gut: a narrative review focusing on high-fat diets.Jonathan Sholl, Lucy Mailing & Thomas Wood - 2021 - MBio 12 (2):e00579-21.
    There is a broad consensus in nutritional-microbiota research that high-fat (HF) diets are harmful to human health, at least in part through their modulation of the gut microbiota. However, various studies also support the inherent flexibility of the human gut and our microbiota’s ability to adapt to a variety of food sources, suggesting a more nuanced picture. In this article, we first discuss some problems facing basic translational research and provide a different framework for thinking about diet and gut health (...)
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  21.  10
    Explaining Health Across the Sciences.Jonathan Sholl & Suresh I. S. Rattan (eds.) - 2020 - Springer Nature.
    This edited volume aims to better understand the multifaceted phenomenon we call health. -/- Going beyond simple views of health as the absence of disease or as complete well-being, this book unites scientists and philosophers. The contributions clarify the links between health and adaptation, robustness, resilience, or dynamic homeostasis, and discuss how to achieve health and healthy aging through practices such as hormesis. -/- The book is divided into three parts and a conclusion: the first part explains health from within (...)
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  22.  23
    Philippe Huneman, Gérard Lambert and Marc Silberstein Classification, Disease and Evidence: New Essays in the Philosophy of Medicine: Dordrecht, Heidelberg, New York, London: Springer, 2015, Series: History, Philosophy and Theory of the Life Sciences, Vol. 7, 211 pp, €83,29.Jonathan Sholl - 2015 - History and Philosophy of the Life Sciences 37 (3):339-341.
  23.  67
    Thought and Repetition in Bergson and Deleuze.Jonathan Sholl - 2012 - Deleuze and Guatarri Studies 6 (4):544-563.
    This essay explores the relation between repetition and thought in Bergson and Deleuze. In Bergson, this relation is seen in the method of intuition by which thought is made to think in time and in the ‘rhythms’ at work in how intuition is a contact with time or life, urging conceptual precision. This framework is used to clarify Deleuze's thought without image as that contingent encounter with the persistent forces of life that demand the perseverance of thought. Far from stressing (...)
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  24.  21
    S teeves D emazeux and P atrick S ingy , The DSM - 5 in Perspective: Philosophical Reflections on the Psychiatric Babel, Dordrecht, Heidelberg, New York, London: Springer, 2015, Series: History, Philosophy and Theory of the Life Sciences, Vol. 10, 238 pp, £90. [REVIEW]Jonathan Sholl - 2018 - History and Philosophy of the Life Sciences 40 (1):15.
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