In psychiatry, pharmacological drugs play an important experimental role in attempts to identify the neurobiological causes of mental disorders. Besides being developed in applied contexts as potential treatments for patients with mental disorders, pharmacological drugs play a crucial role in research contexts as experimental instruments that facilitate the formulation and revision of neurobiological theories of psychopathology. This paper examines the various epistemic functions that pharmacological drugs serve in the discovery, refinement, testing, and elaboration of neurobiological theories of mental disorders. I (...) articulate this thesis with reference to the history of antipsychotic drugs and the evolution of the dopamine hypothesis of schizophrenia in the second half of the twentieth century. I argue that interventions with psychiatric patients through the medium of antipsychotic drugs provide researchers with information and evidence about the neurobiological causes of schizophrenia. This analysis highlights the importance of pharmacological drugs as research tools in the generation of psychiatric knowledge and the dynamic relationship between practical and theoretical contexts in psychiatry. (shrink)

This paper addresses philosophical issues concerning whether mental disorders are natural kinds and how the DSM should classify mental disorders. I argue that some mental disorders (e.g., schizophrenia, depression) are natural kinds in the sense that they are natural classes constituted by a set of stable biological mechanisms. I subsequently argue that a theoretical and causal approach to classification would provide a superior method for classifying natural kinds than the purely descriptive approach adopted by the DSM since DSM-III. My argument (...) suggests that the DSM should classify natural kinds in order to provide predictively useful (i.e., projectable) diagnostic categories and that a causal approach to classification would provide a more promising method for formulating valid diagnostic categories. (shrink)

This paper examines Ian Hacking's analysis of the looping effects of psychiatric classifications, focusing on his recent account of interactive and indifferent kinds. After explicating Hacking's distinction between 'interactive kinds' (human kinds) and 'indifferent kinds' (natural kinds), I argue that Hacking cannot claim that there are 'interactive and indifferent kinds,' given the way that he introduces the interactive-indifferent distinction. Hacking is also ambiguous on whether his notion of interactive and indifferent kinds is supposed to offer an account of classifications or (...) objects of classification. I argue that these conceptual difficulties show that Hacking's account of interactive and indifferent kinds cannot be based on - and should be clearly separated from - his distinction between interactive kinds and indifferent kinds. In clarifying Hacking's account, I argue that interactive and indifferent kinds should be regarded as objects of classification (i.e., kinds of people) that can be identified with reference to a law-like biological regularity and are aware of how they are classified. Schizophrenia and depression are discussed as examples. I subsequently offer reasons for resisting Hacking's claim that the objects of classification in the human sciences - as a result of looping effects - are 'moving targets'. (shrink)

In this article, I argue that depression and suicide are natural kinds insofar as they are classes of abnormal behavior underwritten by sets of stable biological mechanisms. In particular, depression and suicide are neurobiological kinds characterized by disturbances in serotonin functioning that affect various brain areas (i.e., the amygdala, anterior cingulate, prefrontal cortex, and hippocampus). The significance of this argument is that the natural (biological) basis of depression and suicide allows for reliable projectable inferences (i.e., predictions) to be made about (...) individual members of a kind. In the context of assisted suicide, inferences about the decision-making capacity of depressed individuals seeking physician-assisted suicide are of special interest. I examine evidence that depression can hamper the decision-making capacity of individuals seeking assisted suicide and discuss some implications. (shrink)

A large part of the controversy surrounding the publication of DSM-5 stems from the possibility of replacing the purely descriptive approach to classification favored by the DSM since 1980. This paper examines the question of how mental disorders should be classified, focusing on the issue of whether the DSM should adopt a purely descriptive or theoretical approach. I argue that the DSM should replace its purely descriptive approach with a theoretical approach that integrates causal information into the DSM’s descriptive diagnostic (...) categories. The paper proceeds in three sections. In the first section, I examine the goals (viz., guiding treatment, facilitating research, and improving communication) associated with the DSM’s purely descriptive approach. In the second section, I suggest that the DSM’s purely descriptive approach is best suited for improving communication among mental health professionals; however, theoretical approaches would be superior for purposes of treatment and research. In the third section, I outline steps required to move the DSM towards a hybrid system of classification that can accommodate the benefits of descriptive and theoretical approaches, and I discuss how the DSM’s descriptive categories could be revised to incorporate theoretical information regarding the causes of disorders. I argue that the DSM should reconceive of its goals more narrowly such that it functions primarily as an epistemic hub that mediates among various contexts of use in which definitions of mental disorders appear. My analysis emphasizes the importance of pluralism as a methodological means for avoiding theoretical dogmatism and ensuring that the DSM is a reflexive and self-correcting manual. (shrink)

Michael Friedman’s Dynamics of Reason is a welcome contribution to the ongoing articulation of philosophical perspectives for understanding the sciences in the context of post-positivist philosophy of science. Two perspectives that have gained advocacy since the demise of the “received view” are Quinean naturalism and Kuhnian relativism. In his 1999 Stanford lectures, Friedman articulates and defends a neo-Kantian perspective for philosophy of science that opposes both of these perspectives. His proffered neo-Kantian perspective is presented within the context of the problem (...) of theory change or “scientific revolutions,” and its main feature is a conception of scientific knowledge that requires “relativized constitutive a priori principles.” The lectures make up the first part of the book; the second part of the book, “Fruits of Discussion,” is a further elaboration and defence of the ideas advanced in the lectures. The resulting book serves as a useful sequel to Friedman’s impressive historical studies in Foundations of Space-Time Theories, Kant and the Exact Sciences, and Reconsidering Logical Positivism. In the preface, Friedman tells us that this book represents the philosophical viewpoint that he has arrived at as a result of completing these works. As such, it is not surprising that the prominent themes of the book are ones that have occupied Friedman’s attention in the past, viz., the importance of a priori principles in the exact sciences, the conventionalism of the logical positivists, and, more generally, an articulation of what remains defensible in neo-Kantian philosophy of science. (shrink)

This paper explores Paul Feyerabend's (1924-1994) skeptical arguments for "anarchism" in his early writings between 1960 to 1975. Feyerabend's position is encapsulated by his well-known suggestion that the only principle for scientific method that can be defended under all circumstances is: "anything goes." I present Feyerabend's anarchism as a recommendation for pluralism that assumes a realist view of scientific theories. The aims of this paper are threefold: (1) to present a defensible view of Feyerabend's anarchism and its motivations, (2) to (...) articulate the minimal form of realism that such a view presupposes, and (3) to consider the implications and limitations of such a perspective in contemporary philosophy of science. (shrink)

This paper addresses the question of how human science categories yield projectable inferences by critically examining Ron Mallon’s ‘social role’ account of human kinds. Mallon contends that human categories are projectable when a social role produces a homeostatic property cluster (HPC) kind. On this account, human categories are projectable when various social mechanisms stabilize and entrench those categories. Mallon’s analysis obscures a distinction between transitory and robust projectable inferences. I argue that the social kinds discussed by Mallon yield the former, (...) while classifications of biological kinds yield the latter. Classifications from psychiatry (‘schizophrenia,’ ‘hysteria’) are discussed as examples. (shrink)

Abstract Recently, some philosophers of psychiatry (viz., Rachel Cooper and Dominic Murphy) have analyzed the issue of psychiatric classification. This paper expands upon these analyses and seeks to demonstrate that a consideration of the history of the Diagnostic and Statistical Manual of Mental Disorders (DSM) can provide a rich and informative philosophical perspective for critically examining the issue of psychiatric classification. This case is intended to demonstrate the importance of history for philosophy of psychiatry, and more generally, the potential benefits (...) of historically-informed approaches to philosophy of science. (shrink)

This paper concerns the recent debate on the nature and motivations of the epistemological project advanced in Rudolf Carnap's (1891-1970) Aufbau. Much of this debate has been initiated by Michael Friedman and Alan Richardson who argue (against the received view of the Aufbau as a foundationalist defense of empiricism) that Carnap's epistemological project is located in the tradition of neo-Kantian epistemology. On this revisionist reading of the Aufbau, Carnap's project is not motivated to address traditional empiricist problems regarding the justification (...) of knowledge, but rather to show how objective knowledge is possible. A central aspect of the Aufbau that is neglected in the revisionists' analysis is the role of epistemic justification in Carnap's project. The aim of the present study is to argue that although the general epistemology in the Aufbau can be cast as neo-Kantian, Carnap's method of construction theory (or rational reconstruction) is formulated precisely as an empiricist method for the justification of conceptual knowledge. Construction theory radically redefines `empirical justification' into a formal-conventional notion, and is part of Carnap's more general agenda of redefining epistemology as a purely formal discipline. (shrink)

In the 1960s and 1970s, Hilary Putnam articulated a notion of relativized apriority that was motivated to address the problem of scientific change. This paper examines Putnam’s account in its historical context and in relation to contemporary views. I begin by locating Putnam’s analysis in the historical context of Quine’s rejection of apriority, presenting Putnam as a sympathetic commentator on Quine. Subsequently, I explicate Putnam’s positive account of apriority, focusing on his analysis of the history of physics and geometry. In (...) the remainder of the paper, I explore connections between Putnam’s account of relativized a priori principles and contemporary views. In particular, I situate Putnam’s account in relation to analyses advanced by Michael Friedman, David Stump, and William Wimsatt. From this comparison, I address issues concerning whether a priori scientific principles are appropriately characterized as “constitutive” or “entrenched”. I argue that these two features need to be clearly distinguished, and that only the constitutive function is essential to apriority. By way of conclusion, I explore the relationship between the constitutive function of a priori principles and entrenchment. (shrink)

This highly multidisciplinary collection discusses an increasingly important topic among scholars in science and technology studies: objectivity in science. It features eleven essays on scientific objectivity from a variety of perspectives, including philosophy of science, history of science, and feminist philosophy. Topics addressed in the book include the nature and value of scientific objectivity, the history of objectivity, and objectivity in scientific journals and communities. Taken individually, the essays supply new methodological tools for theorizing what is valuable in the pursuit (...) of objective knowledge and for investigating its history. The essays offer many starting points, while suggesting new avenues of research. Taken collectively, the essays exemplify the very virtues of objectivity that they theorize—in reading them together, the reader can sense various anxieties about the dangerously subjective in our age and locate commonalities of concern as well as differences of approach. As a result, the volume offers an expansive vision of a research community seeking a communal understanding of its own methods and its own epistemic anxieties, struggling to enunciate the key problems of knowledge of our time and offer insight into how to overcome them. -/- (Contributors: Alex Csiszar, Scott Edgar, Peter Galison, Ian Hacking, Sandra Harding, Moira Howes, Paolo Savoia, Judy Segal, Joan Steigerwald, and Alison Wylie). (shrink)

This paper concerns Jean Piaget's (1896–1980) philosophy of science and, in particular, the picture of scientific development suggested by his theory of genetic epistemology. The aims of the paper are threefold: (1) to examine genetic epistemology as a theory concerning the growth of knowledge both in the individual and in science; (2) to explicate Piaget's view of ‘scientific progress’, which is grounded in his theory of equilibration; and (3) to juxtapose Piaget's notion of progress with Thomas Kuhn's (1922–1996). Issues of (...) scientific continuity, scientific realism and scientific rationality are discussed. It is argued that Piaget's view highlights weaknesses in Kuhn's ‘discontinuous’ picture of scientific change. (shrink)

According to David Chalmers, the hard problem of consciousness consists of explaining how and why qualitative experience arises from physical states. Moreover, Chalmers argues that materialist and reductive explanations of mentality are incapable of addressing the hard problem. In this chapter, I suggest that Chalmers’ hard problem can be usefully distinguished into a ‘how question’ and ‘why question,’ and I argue that evolutionary biology has the resources to address the question of why qualitative experience arises from brain states. From this (...) perspective, I discuss the different kinds of evolutionary explanations (e.g., adaptationist, exaptationist, spandrel) that can explain the origins of the qualitative aspects of various conscious states. This argument is intended to clarify which parts of Chalmers’ hard problem are amenable to scientific analysis. (shrink)

This chapter examines philosophical issues surrounding the classification of mental disorders by the Diagnostic and Statistical Manual of Mental Disorders (DSM). In particular, the chapter focuses on issues concerning the relative merits of descriptive versus theoretical approaches to psychiatric classification and whether the DSM should classify natural kinds. These issues are presented with reference to the history of the DSM, which has been published regularly by the American Psychiatric Association since 1952 and is currently in its fifth edition. While the (...) first two editions of the DSM adopted a theoretical (psychoanalytic) and etiological approach to classification, subsequent editions of the DSM have adopted an atheoretical and purely descriptive (“neo-Kraepelinian”) approach. It is argued that largest problem with the DSM at present—viz., its failure to provide valid diagnostic categories—is directly related to the purely descriptive methodology championed by the DSM since the third edition of the DSM. In light of this problem, the chapter discusses the prospects of a theoretical and causal approach to psychiatric classification and critically examines the assumption that the DSM should classify natural kinds. (shrink)

An essential overview of this important intellectual movement. This latest volume in the longest-standing and most influential series in the field of the philosophy of science extends and expands on the discipline's recent historical turn. These essays take up the historical, sociological, and philosophical questions surrounding the particular intellectual movement of logical empiricism--both its emigration from Europe to North America in the 1930s and 1940s and its development in North America through the 1940s and 1950s. With an introduction placing them (...) in their philosophical and historical context, these essays bear witness to the fact that the history of the philosophy of science, far more than a mere repository of anecdote and chronology, might be able to produce a decisive transformation in the philosophy of science itself. (shrink)

This dissertation examines psychiatry from a philosophy of science perspective, focusing on issues of realism and classification. Questions addressed in the dissertation include: What evidence is there for the reality of mental disorders? Are any mental disorders natural kinds? When are disease explanations of abnormality warranted? How should mental disorders be classified? -/- In addressing issues concerning the reality of mental disorders, I draw on the accounts of realism defended by Ian Hacking and William Wimsatt, arguing that biological research on (...) mental disorders supports the inference that some mental disorders (e.g., schizophrenia, mood disorders, and anxiety disorders) are real theoretical entities, and that the evidence supporting this inference is causal and abductive. In explicating the nature of such entities, I argue that real mental disorders are natural kinds insofar as they are natural classes of abnormal behavior whose members share the same causal structure. I present this position in terms of Richard Boyd’s homeostatic cluster property theory of natural kinds, and argue that this perspective reveals limitations of Hacking’s account on the looping effects of human kinds, which suggests that the objects classified by psychiatrists are unstable entities. I subsequently argue that a subset of mental disorders (e.g., schizophrenia and Down syndrome) are mental illnesses insofar as they are disorders caused by a dysfunctional biological process that leads to harmful consequences for individuals. I present this analysis against Thomas Szasz’s argument that mental illness is a myth. -/- In addressing issues of psychiatric classification, my analysis focuses on the Diagnostic and Statistical Manual of Mental Disorders (DSM), which has been published regularly by the American Psychiatric Association since 1952, and is currently in its fourth edition. After examining the history of DSM in the twentieth century, and in particular, DSM’s shift to an atheoretical and purely descriptive system in the 1980s, I consider the relative merits of descriptive versus causal systems of classification. Drawing on Carl Hempel’s analysis of taxonomic systems in psychiatry, I argue that a causal classification system would provide a superior approach to psychiatric classification than the descriptive system currently favored by DSM. (shrink)

Recently, some philosophers of science (e.g., Gürol Irzik, Michael Friedman) have challenged the ‘received view’ on the relationship between Rudolf Carnap and Thomas Kuhn, suggesting that there is a close affinity (rather than opposition) between their philosophical views. In support of this argument, these authors cite Carnap and Kuhn’s similar views on incommensurability, theory-choice, and scientific revolutions. Against this revisionist view, I argue that the philosophical relationship between Carnap and Kuhn should be regarded as opposed rather than complementary. In particular, (...) I argue that a consideration of the fundamentally disparate nature of the broader philosophical projects of Carnap (logic of science) and Kuhn (providing a theory of scientific revolutions)renders the alleged similarities between their views superficial in comparison to their fundamental differences. In defense of the received view, I suggest that Carnap and Kuhn are model representatives of two contrasting styles of doing philosophy of science, viz., logical analysis and historical analysis respectively. This analysis clarifies the role played by Kuhn’s Structure of Scientific Revolutions in the demise of logical empiricism in the second half of the twentieth-century. (shrink)

En este trabajo pretendemos abordar la teoría del Intuicionismo social, realizada por el psicólogo Jonathan Haidt en oposición al modelo racionalista de Piaget y Kohlberg. Analizaremos sus elementos principales y especialmente sus implicaciones normativas. En particular nos centraremos en su conocida teoría del «desconcierto moral» con la que pretende mostrar la desconexión existente entre el juicio moral y la reflexión como dos procesos independientes.

Ludwig Wittgenstein y Jonathan Swift. El primero desde la filosofía y el segundo desde la literatura. Por una parte, están las anotaciones de Wittgenstein en sus Investigaciones Filosóficas y en el libro Sobre la certeza . Por otra parte, está la novela de Swift titulada Los Viajes de Gulliver . Ambos autores, a pesar de sus diferencias discursivas, plantean un asunto problemático respecto al quehacer filosófico: los giros y malabarismos lingüísticos en los que suele caer la filosofía por su (...) afán de certezas y de establecer principios universales. A partir de las inquietudes de Wittgenstein y las parodias de Jonathan Swift, se realiza un diagnóstico del quehacer filosófico desde sus manías y sus hábitos discursivos. Wittgenstein nos deja las preguntas abiertas. Swift nos deja la posibilidad de responder desde el ámbito de la risa. Y en el presente ensayo se pretende partir de ambos autores para hablar de la filosofía desde el lugar de la comedia. (shrink)

La concepciiin de la tecnología de Bacon aparece dispersa en el Novum Organum, la segunda parte de su obra inacabada, Instauratio Magna. Bacon sienta alli un precedente para el papel que la filosofía contemporánea de la ciencia concede a la tecnologia en la constnicción de la racionalidad cie..

In psychiatry, pharmacological research has played a crucial role in the formulation, revision, and refinement of neurobiological theories of psychopathology. Besides being utilized as potential treatments for various mental disorders, pharmacological drugs play an important epistemic role as experimental instruments that help scientists uncover the neurobiological underpinnings of mental disorders (Tsou, 2012). Interventions with psychiatric patients using pharmacological drugs provide researchers with information about the neurobiological causes of mental disorders that cannot be obtained in other ways. This important source (...) of evidence for the biological causes of mental disorder is often overlooked in philosophical analyses of psychiatry, especially in skeptical analyses that debase the biological aspects of psychopathology (e.g., Szasz, 1960; Scheff, 1963; Laing, 1967). In discussing pharmacological interventions as a form of evidence for the physical basis of mental disorders, this paper aims to clarify the nature, reliability, and limitations of this evidence. In addition, it illustrates the central role that pharmacological findings in applied clinical contexts play in the acquisition of neurobiological knowledge in research contexts. (shrink)

La crítica del siglo XX ha hecho ver que varias de las obras de Jonathan Swift están vinculadas tanto con las condiciones sociales, políticas y culturales irlandesas como con algunas teorías, las cuales han quedado en la oscuridad para algunas investigaciones literarias, a pesar del hecho de que pue..

Reasoning es una obra monumental de más de mil páginas editada en estrecha colaboración por el filósofo Jonathan E. Adler y el psicólogo Lance J. Rips para esclarecer el intrincado campo de investigación relacionado con los fundamentos de la inferencia y, en general, del razonamiento humano. En la actualidad, en pocos casos va unido el trabajo de compilar y editar textos científicos con el afán enciclopédico: un proyecto editorial que sobrepasa con razón los objetivos de la mayor parte de (...) los libros editados para la recopilación de artículos en torno a un mismo tema de investigación. Reasoning supone un empeño de características enciclopédicas: ha conseguido convertirse en una referencia obligada desde que saliera a la luz en 2008 para ofrecer al lector especialista artículos científicos de las más reputadas y consolidadas voces en aquellos campos de conocimiento presentes ya en los proyectos enciclopédicos europeos del siglo de las luces, a saber: el significado del racionalismo, los límites imputables a la naturaleza del conocimiento humano, las paradojas presentes en la inducción, etc. (shrink)

Twentieth century criticism has pointed out that many of Jonathan Swift´s works are linked with Irish conditions as well as some theories, which have remained particularly obscure for many literary investigations, in spite of the fact that they might be the key to a better understanding of the Irish author. Remarkable scholars noticed three main theoretical fields: economical, scientific and philosophical/linguistic. In the following pages, we will take into account some recent works on Swift in order to point out (...) how A Modest Proposal develops its satiric energy from a hesitating biopolitics, which criticises modernity and some of its knowledge, and also casts some light on human being’s contemporary condition. La crítica del siglo XX ha hecho ver que varias de las obras de Jonathan Swift están vinculadas tanto con las condiciones sociales, políticas y culturales irlandesas como con algunas teorías, las cuales han quedado en la oscuridad para algunas investigaciones literarias, a pesar del hecho de que puedan ser la clave de un mejor entendimiento del autor irlandés. Importantes investigadores han distinguido tres campos teóricos principales a los que se refiere la obra de Swift: el económico, el científico y el filosófico/lingüístico. En las siguientes páginas, tomaremos en cuenta algunos de los trabajos recientes sobre Swift con la intención de hacer ver que Una Modesta Proposición desarrolla su fuerza satírica a partir de una biopolítica que duda y critica la modernidad y algunos de los saberes de la modernidad, arrojando luz acerca de la condición contemporánea del ser humano. (shrink)

Escribir acerca de la muerte en la literatura trata de responder a una de las preguntas que, desde siempre, se ha hecho el hombre de cualquier cultura, época o creencia. Vida y muerte son las dos caras de la misma moneda y no podemos ignorar que todo lo que nace acaba pereciendo. El Oráculo en La llamada de los muertos, de Laura Gallego, nos recuerda que la vida por sí misma no es nada, si no va acompañada por la muerte, (...) su compañera: "No comprendes que cada cosa tiene su tiempo y su edad, y que si bien la vida es algo maravilloso, también la muerte es necesaria para toda criatura" (pág. 31). En El coleccionista de relojes extraordinarios es la propia muerte quien le da este consejo a Jonathan Hadley: "Limítate a vivir, eses es tu trabajo. Cuando llegue tu hora, yo vendré a buscarte. Ese es mi trabajo. Nos veremos entonces�" Jonathan Hadley (pág. 154). Y es que no se puede huir de la Muerte por mucho que nos empeñemos. (shrink)

La Constitución pastoral Gaudium et spes es la lupa por la que se intentarávisualizar el entramado trinitario en el conjunto de relaciones que conformanla naturaleza humana: sexualidad, afectividad y corporeidad; ya que a la base desu cuerpo teórico se halla el principio antropológico de la teología: el hombreha sido creado a imagen y semejanza de Dios Trinidad. Por tanto, elhombre es trinidad por participación. La pregunta que subyace es ¿de quémanera comprender a la persona humana como un ser trinitario? Para (...) esto esindispensable adentrarse en el misterio de la Trinidad con el fin de esclarecer elmisterio del hombre. (shrink)