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  1.  98
    Research Site Monitoring for Compliance with Ethics Regulatory Standards: Review of Experience From Uganda. [REVIEW]Joseph Ochieng, Julius Ecuru, Frederick Nakwagala & Paul Kutyabami - 2013 - BMC Medical Ethics 14 (1):23.
    On site monitoring of research is one of the most effective ways to ensure compliance during research conduct. However, it is least carried out primarily for two reasons: presumed high costs both in terms of human resources and finances; and the lack of a clear framework for undertaking site monitoring. In this paper we discuss a model for research site monitoring that may be cost effective and feasible in low resource settings.
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  2.  23
    Informed Consent Practices for Surgical Care at University Teaching Hospitals: A Case in a Low Resource Setting.Joseph Ochieng, Charles Ibingira, William Buwembo, Ian Munabi, Haruna Kiryowa, David Kitara, Paul Bukuluki, Gabriel Nzarubara & Erisa Mwaka - 2014 - BMC Medical Ethics 15 (1):40.
    Informed consent in medical practice is essential and a global standard that should be sought at all the times doctors interact with patients. Its intensity would vary depending on the invasiveness and risks associated with the anticipated treatment. To our knowledge there has not been any systematic review of consent practices to document best practices and identify areas that need improvement in our setting. The objective of the study was to evaluate the informed consent practices of surgeons at University teaching (...)
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  3.  15
    Evolution of Research Ethics in a Low Resource Setting: A Case for Uganda.Joseph Ochieng, Erisa Mwaka, Betty Kwagala & Nelson Sewankambo - 2020 - Developing World Bioethics 20 (1):50-60.
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  4.  5
    A Scoping Review of Genetics and Genomics Research Ethics Policies and Guidelines for Africa.Joseph Ochieng, Nelson K. Sewankambo, John Barugahare, Betty Kwagala, Juli M. Bollinger, Erisa Mwaka, Betty Cohn & Joseph Ali - 2021 - BMC Medical Ethics 22 (1):1-15.
    BackgroundGenetics and genomics research is increasingly being conducted around the world; yet, researchers and research oversight entities in many countries have struggled with ethical challenges. A range of ethics and regulatory issues need to be addressed through comprehensive policy frameworks that integrate with local environments. While important efforts have been made to enhance understanding and awareness of ethical dimensions of GGR in Africa, including through the H3Africa initiative, there remains a need for in-depth policy review, at a country-level, to inform (...)
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  5.  12
    Ethical and Human Rights Considerations in Public Health in Low and Middle-Income Countries: An Assessment Using the Case of Uganda’s Responses to COVID-19 Pandemic.Nelson K. Sewankambo, Joseph Ochieng, Erisa Mwaka Sabakaki, Fredrick Nelson Nakwagala & John Barugahare - 2020 - BMC Medical Ethics 21 (1):1-12.
    BackgroundIn response to COVID-19 pandemic, the Government of Uganda adopted public health measures to contain its spread in the country. Some of the initial measures included refusal to repatriate citizens studying in China, mandatory institutional quarantine, and social distancing. Despite being a public health emergency, the measures adopted deserve critical appraisal using an ethics and human rights approach. The goal of this paper is to formulate an ethics and human rights criteria for evaluating public health measures and use it to (...)
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  6.  7
    Researchers’ Perspectives on Return of Individual Genetics Results to Research Participants: A Qualitative Study.Erisa Sabakaki Mwaka, Deborah Ekusai Sebatta, Joseph Ochieng, Ian Guyton Munabi, Godfrey Bagenda, Deborah Ainembabazi & David Kaawa-Mafigiri - 2021 - Global Bioethics 32 (1):15-33.
    Genetic results are usually not returned to research participants in Uganda despite their increased demand. We report on researchers’ perceptions and experiences of return of individual genetic research results. The study involved 15 in-depth interviews of investigators involved in genetics and/or genomic research. A thematic approach was used to interpret the results. The four themes that emerged from the data were the need for return of individual results including incidental findings, community engagement and the consenting process, implications and challenges to (...)
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  7. Collection and Use of Human Materials During TB Clinical Research; a Review of Practices.Nelson Sewankambo, Betty Kwagala & Joseph Ochieng - 2022 - BMC Medical Ethics 23 (1):1-6.
    BackgroundHuman biological materials are usually stored for possible future use in research because they preserve valuable biological information, save time and resources, which would have been spent on collection of fresh samples. However, use of these materials may pose ethical challenges such as unauthorized disclosure of genetic information, which can result in dire consequences for individuals or communities including discrimination, stigma, and psychological harm; has biosecurity implications; and loss of control or ownership of samples or data. To understand these problems (...)
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  8.  1
    Capacity of Community Advisory Boards for Effective Engagement in Clinical Research: A Mixed Methods Study.Joseph Ochieng, Winfred Badanga Nazziwa, Irene Seryazi Semakula, Fedress Kaliba, Collins Agaba, Mastula Nanfuka, Andrew Mijumbi & Levicatus Mugenyi - 2021 - BMC Medical Ethics 22 (1):1-7.
    BackgroundCommunity engagement is a key component in health research. One of the ways health researchers ensure community engagement is through Community Advisory Boards. The capacity of CABs to properly perform their role in clinical research has not been well described in many resource limited settings. In this study, we assessed the capacity of CABs for effective community engagement in Uganda.MethodsWe conducted a cross sectional study with mixed methods. We used structured questionnaires and key informant interviews to collect data from CAB (...)
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  9.  1
    Perspectives and Ethical Considerations for Return of Genetics and Genomics Research Results: A Qualitative Study of Genomics Researchers in Uganda.Nelson K. Sewankambo, Joseph Ali, Deborah Ekusai-Sebatta, Erisa Mwaka, John Barugahare, Betty Kwagala & Joseph Ochieng - 2021 - BMC Medical Ethics 22 (1):1-9.
    BackgroundThe return of genetics and genomics research results has been a subject of ongoing global debate. Such feedback is ethically desirable to update participants on research findings particularly those deemed clinically significant. Although there is limited literature, debate continues in African on what constitutes appropriate practice regarding the return of results for genetics and genomics research. This study explored perspectives and ethical considerations of Ugandan genomics researchers regarding the return of genetics and genomics research results.MethodsThis was a qualitative study that (...)
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