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Julian J. Koplin [16]Julian Koplin [9]Julian K. Koplin [1]
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  1.  15
    Moral Uncertainty and the Farming of Human-Pig Chimeras.Julian Koplin & Dominic Wilkinson - 2019 - Journal of Medical Ethics 45 (7):440-446.
    It may soon be possible to generate human organs inside of human-pig chimeras via a process called interspecies blastocyst complementation. This paper discusses what arguably the central ethical concern is raised by this potential source of transplantable organs: that farming human-pig chimeras for their organs risks perpetrating a serious moral wrong because the moral status of human-pig chimeras is uncertain, and potentially significant. Those who raise this concern usually take it to be unique to the creation of chimeric animals with (...)
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  2.  74
    Assessing the Likely Harms to Kidney Vendors in Regulated Organ Markets.Julian Koplin - 2014 - American Journal of Bioethics 14 (10):7-18.
    Advocates of paid living kidney donation frequently argue that kidney sellers would benefit from paid donation under a properly regulated kidney market. The poor outcomes experienced by participants in existing markets are often entirely attributed to harmful black-market practices. This article reviews the medical and anthropological literature on the physical, psychological, social, and financial harms experienced by vendors under Iran's regulated system of donor compensation and black markets throughout the world and argues that this body of research not only documents (...)
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  3.  14
    Moral Limits of Brain Organoid Research.Julian J. Koplin & Julian Savulescu - 2019 - Journal of Law, Medicine and Ethics 47 (4):760-767.
    Brain organoid research raises ethical challenges not seen in other forms of stem cell research. Given that brain organoids partially recapitulate the development of the human brain, it is plausible that brain organoids could one day attain consciousness and perhaps even higher cognitive abilities. Brain organoid research therefore raises difficult questions about these organoids' moral status – questions that currently fall outside the scope of existing regulations and guidelines. This paper shows how these gaps can be addressed. We outline a (...)
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  4.  84
    Germline Gene Editing and the Precautionary Principle.Julian J. Koplin, Christopher Gyngell & Julian Savulescu - 2020 - Bioethics 34 (1):49-59.
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  5.  15
    Human‐Animal Chimeras: The Moral Insignificance of Uniquely Human Capacities.Julian J. Koplin - 2019 - Hastings Center Report 49 (5):23-32.
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  6.  4
    Why genomics researchers are sometimes morally required to hunt for secondary findings.Julian J. Koplin, Julian Savulescu & Danya F. Vears - 2020 - BMC Medical Ethics 21 (1):1-11.
    Genomic research can reveal ‘unsolicited’ or ‘incidental’ findings that are of potential health or reproductive significance to participants. It is widely thought that researchers have a moral obligation, grounded in the duty of easy rescue, to return certain kinds of unsolicited findings to research participants. It is less widely thought that researchers have a moral obligation to actively look for health-related findings. This paper examines whether there is a moral obligation, grounded in the duty of easy rescue, to actively hunt (...)
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  7.  26
    Commodification and Human Interests.Julian Koplin - 2018 - Journal of Bioethical Inquiry 15 (3):429-440.
    In Markets Without Limits and a series of related papers, Jason Brennan and Peter Jaworski argue that it is morally permissible to buy and sell anything that it is morally permissible to possess and exchange outside of the market. Accordingly, we should open markets in “contested commodities” including blood, gametes, surrogacy services, and transplantable organs. This paper clarifies some important aspects of the case for market boundaries and in so doing shows why there are in fact moral limits to the (...)
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  8.  18
    Burden of Proof in Bioethics.Julian J. Koplin & Michael J. Selgelid - 2015 - Bioethics 29 (9):597-603.
    A common strategy in bioethics is to posit a prima facie case in favour of one policy, and to then claim that the burden of proof falls on those with opposing views. If the burden of proof is not met, it is claimed, then the policy in question should be accepted. This article illustrates, and critically evaluates, examples of this strategy in debates about the sale of organs by living donors, human enhancement, and the precautionary principle. We highlight general problems (...)
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  9.  34
    The Body as Gift, Commodity, or Something in Between: Ethical Implications of Advanced Kidney Donation.Julian J. Koplin - 2017 - Journal of Medicine and Philosophy 42 (5):575-596.
    An innovative program recently initiated at the University of California, Los Angeles Medical Center allows people to donate a kidney in exchange for a voucher that a loved one can redeem for a kidney if and when needed. As a relatively new practice, the ethical implications of advanced kidney donation have not yet been widely discussed. This paper reflects on some of the bioethical issues at stake in this new donation program, as well as some broader philosophical issues related to (...)
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  10.  12
    Choice, Pressure and Markets in Kidneys.Julian Koplin - 2018 - Journal of Medical Ethics 44 (5):310-313.
    We do not always benefit from the expansion of our choice sets. This is because some options change the context in which we must make decisions in ways that render us worse off than we would have been otherwise. One promising argument against paid living kidney donation holds that having the option of selling a ‘spare’ kidney would impact people facing financial pressures in precisely this way. I defend this argument from two related criticisms: first, that having the option to (...)
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  11.  8
    From Blood Donation to Kidney Sales: The Gift Relationship and Transplant Commercialism.Julian J. Koplin - 2015 - Monash Bioethics Review 33 (2-3):102-122.
    In The Gift Relationship, Richard Titmuss argued that the practice of altruistic blood donation fosters social solidarity while markets in blood erode it. This paper considers the implications of this line of argument for the organ market debate. I defend Titmuss’ arguments against a number of criticisms and respond to claims that Titmuss’ work is not relevant to the context of live donor organ transplantation. I conclude that Titmuss’ arguments are more resilient than many advocates of organ markets suggest, and (...)
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  12.  28
    Beyond Fair Benefits: Reconsidering Exploitation Arguments Against Organ Markets.Julian J. Koplin - 2018 - Health Care Analysis 26 (1):33-47.
    One common objection to establishing regulated live donor organ markets is that such markets would be exploitative. Perhaps surprisingly, exploitation arguments against organ markets have been widely rejected in the philosophical literature on the subject. It is often argued that concerns about exploitation should be addressed by increasing the price paid to organ sellers, not by banning the trade outright. I argue that this analysis rests on a particular conception of exploitation, and outline two additional ways that the charge of (...)
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  13.  20
    Response to Open Peer Commentaries on “Assessing the Likely Harms to Kidney Vendors in Regulated Organ Markets”.Julian Koplin - 2014 - American Journal of Bioethics 14 (10):1-3.
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  14.  5
    The Ambiguous Lessons of the Iranian Model of Paid Living Kidney Donation: Fry-Revere, S. . The Kidney Sellers: A Journey of Discovery in Iran.Julian J. Koplin - 2014 - Monash Bioethics Review 32 (3-4):284-290.
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  15.  16
    Emerging Moral Status Issues. [REVIEW]Christopher Gyngell & Julian J. Koplin - 2020 - Monash Bioethics Review 38 (2):95-104.
    Many controversies in bioethics turn on questions of moral status. Some moral status issues have received extensive bioethical attention, including those raised by abortion, embryo experimentation, and animal research. Beyond these established debates lie a less familiar set of moral status issues, many of which are tied to recent scientific breakthroughs. This review article surveys some key developments that raise moral status issues, including the development of in vitro brains, part-human animals, “synthetic” embryos, and artificial womb technologies. It introduces the (...)
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  16.  6
    Consequences and Kidneys in Advance.Julian J. Koplin - forthcoming - International Journal of Applied Philosophy.
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  17.  8
    Consequences and Kidneys.Julian J. Koplin - 2017 - International Journal of Applied Philosophy 31 (2):137-148.
    Kidney for Sale by Owner discusses a range of different arguments that can be offered in defence of live donor kidney markets. Although Cherry’s case for establishing such markets does not rest on consequentialist considerations, Cherry nonetheless suggests that allowing the sale of organs would have net positive consequences. He argues that both renal failure patients and people living in poverty could benefit from participating in the market, and further claims that a legal trade in organs would not shape society (...)
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  18.  11
    How Should We Treat Human–Pig Chimeras, Non-Chimeric Pigs and Other Beings of Uncertain Moral Status?Julian Koplin & Dominic Wilkinson - 2019 - Journal of Medical Ethics 45 (7):457-458.
    Our recent article begins by describing a new technique for creating human–animal chimeras. This technique—known as interspecies blastocyst complementation—may enable us to generate human organs inside of human–pig chimeras. One central concern about farming human–pig chimeras for their organs is that their moral status would be uncertain and potentially significant. Our article is partly, but not only, about such concerns. At the heart of our paper are two broader questions. First, how should we treat beings of uncertain moral status? And (...)
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  19.  5
    ‘It’s Not Worse Than Eating Them’: The Limits of Analogy in Bioethics.Julian J. Koplin - 2020 - Monash Bioethics Review 38 (2):129-145.
    Bioethicists often defend novel practices by drawing analogies with practices that we are already familiar with and currently tolerate. If some novel practice is less bad than some widely-accepted practice, then we cannot rightly reject it. Using the bioethics literature on xenotransplantation and interspecies blastocyst complementation as a case study, I show how this style of argument can go awry. The key problem is that our moral intuitions about familiar practices can be distorted by their seeming normality. When considering the (...)
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  20.  8
    Julian J. Koplin Replies.Julian J. Koplin - 2020 - Hastings Center Report 50 (1):46-46.
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  21. Kidney Sales and the Burden of Proof.Julian Koplin & Michael Selgelid - 2019 - Journal of Practical Ethics 7 (3):32-53.
    Janet Radcliffe Richards’ The Ethics of Transplants outlines a novel framework for moral inquiry in practical contexts and applies it to the topic of paid living kidney donation. In doing so, Radcliffe Richards makes two key claims: that opponents of organ markets bear the burden of proof, and that this burden has not yet been satisfied. This paper raises four related objections to Radcliffe Richards’ methodological framework, focusing largely on how Radcliffe Richards uses this framework in her discussion of kidney (...)
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  22.  8
    Lessons From Frankenstein 200 Years On: Brain Organoids, Chimaeras and Other ‘Monsters’.Julian Koplin & John Massie - 2021 - Journal of Medical Ethics 47 (8):567-571.
    Mary Shelley’s Frankenstein has captured the public imagination ever since it was first published over 200 years ago. While the narrative reflected 19th-century anxieties about the emerging scientific revolution, it also suggested some clear moral lessons that remain relevant today. In a sense, Frankenstein was a work of bioethics written a century and a half before the discipline came to exist. This paper revisits the lessons of Frankenstein regarding the creation and manipulation of life in the light of recent developments (...)
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  23.  1
    Organs, Embryos, and Part-Human Chimeras: Further Applications of the Social Account of Dignity.Julian Koplin - 2018 - Monash Bioethics Review 36 (1-4):86-93.
    In their recent paper in this journal, Zümrüt Alpinar-Şencan and colleagues review existing dignity-based objections to organ markets and outline a new form of dignity-based objection they believe has more merit: one grounded in a social account of dignity. This commentary clarifies some aspects of the social account of dignity and then shows how this revised account can be applied to other perennial issues in bioethics, including the ethics of human embryo research and the ethics of creating part-human chimeras.
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  24.  3
    The Moral Relevance of Humanization.Julian J. Koplin - 2021 - American Journal of Bioethics 21 (1):59-61.
    Greely’s target article outlines six categories of ethical issues associated with human brain surrogate research. Some of these issues are familiar from other research contexts; others, less...
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  25.  4
    Old Challenges or New Issues? Genetic Health Professionals’ Experiences Obtaining Informed Consent in Diagnostic Genomic Sequencing.Danya F. Vears, Pascal Borry, Julian Savulescu & Julian K. Koplin - forthcoming - Ajob Empirical Bioethics:1-12.
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  26.  5
    Old Challenges or New Issues? Genetic Health Professionals’ Experiences Obtaining Informed Consent in Diagnostic Genomic Sequencing.Danya F. Vears, Pascal Borry, Julian Savulescu & Julian J. Koplin - 2021 - AJOB Empirical Bioethics 12 (1):12-23.
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