In a series of related essays, Dr Parkinson argues that both science and religion are at a crossroads, because in both cases their current paradigms are breaking down. In science, Einstein’s General Relativity has left an unbridgeable gap between quantum physics and the new cosmology and, in the West, the gap between the story told by modern scholarship and “gospel truth” has become equally wide. What for two millennia has been considered to be historical fact is now seen often (...) to be not only pious myth but deliberate falsification. The author adds something new and positive – but controversial- to the debate, in arguing that a future science and religion must be symbiotic. That is to say, in being true to their most basic principles of truth-seeking, both will find themselves to be not merely harmonious but mutually supporting and illuminating. When the evidence for this is fully, and honestly, assessed, the “phoney war” between science and religion can be seen for what it is. The question under all the questions is this: if simple honesty is an essential part of both science and religion, can either continue to survive with what J. K. Galbraith called “institutional truth?”. (shrink)
This paper is concerned with two theories of history—those of Hegel and of Marx. Its primary aim is to clarify. The writings of Hegel are notoriously obscure, and those of Marx have been variously interpreted, so there is room for a paper which tries to ensure that when the theories of history propounded by Marx and Hegel are criticized, what are criticized are views which they actually held. It is no part of this paper's thesis that, in his theory of (...) history, Marx consciously borrowed from Hegel. But it will be argued that there is more of Hegel in Marx than is sometimes supposed, and that if this fact is ignored one seriously distorts Marx. (shrink)
The concept of freedom is one which Hegel thought of very great importance; indeed, he believed that it is the central concept in human history. ‘Mind is free’, he wrote, ‘and to actualise this, its essence – to achieve this excellence – is the endeavour of the worldmind in world-history’ . Those who already have an interest in Hegel will doubtless be interested in his views on a topic which he thought so important; on the other hand, the many philosophers (...) who are either indifferent to or hostile to Hegel may point out that it does not follow that, because the subject of freedom interested Hegel, his views about this subject are of general interest. It will be the aim of this paper to show that they are of general interest; in the meantime, it may be recalled that Isaiah Berlin has argued that Hegel's concept of freedom is one of a type, called by him the concept of positive freedom, which is ‘at the heart of many of the nationalist, communist, authoritarian and totalitarian creeds of our day’. It will surely be worth while to see to what extent this is true of Hegel, and to what extent Hegel's views about freedom are true. (shrink)
Parkinson’s Disease can be treated with the use of microelectrode recording and stimulation. This paper presents a data stream classifier that analyses raw data from micro-electrodes and decides whether the measurements were taken from the subthalamic nucleus or not. The novelty of the proposed approach is based on the fact that distances based on raw data are used. Two distances are investigated in this paper, i.e. Normalized Compression Distance and Lempel-Ziv Jaccard Distance. No new features needed to be extracted (...) due to the fact that in the case of high-dimensional data the process is extremely time-consuming. The k-nearest neighbour was chosen as the classifier due to its simplicity, which is essential in data stream classification. Results obtained from classifiers based on k-NN: k-NN, k-NN were compared with Probabilistic Approximate Window ; k-NN with Probabilistic Approximate Window and Adaptive Windowing ; and Self Adjusting Memory k-NN, which use the proposed distances, with the performance of the same classifiers but using standard Euclidean distance. Prequential accuracy was chosen as the performance measure. The results of the experiments performed with the described approach are in most cases better, i.e. the performance measures for kNN classifiers that use NCD and LZJD distances are better by up to 8.5 per cent and 14 per cent, respectively. Moreover, the proposed approach performs better when compared with other stream classification algorithms, i.e. Hoeffding Tree, Naive Bayes, and Leveraging Bagging. In the discussed case, an improvement of classification rate of up to 17.9 per cent when using Lempel-Ziv Jaccard Distance instead of the Euclidean was noted. (shrink)
PURPOSE: To evaluate the effects of social support on comprehension and recall of consent form information in a study of Parkinson disease patients and their caregivers.DESIGN and METHODS: Comparison of comprehension and recall outcomes among participants who read and signed the consent form accompanied by a family member/friend versus those of participants who read and signed the consent form unaccompanied. Comprehension and recall of consent form information were measured at one week and one month respectively, using Part A of (...) the Quality of Informed Consent Questionnaire .RESULTS: The mean age of the sample of 143 participants was 71 years . Analysis of covariance was used to compare QuIC scores between the intervention group and control group . In the 1-week model, no statistically significant intervention effect was found . However, the intervention status by patient status interaction was statistically significant . In the 1-month model, no statistically significant intervention effect was found . Again, however, the intervention status by patient status interaction was statistically significant . At both time periods, intervention group patients scored higher on the QuIC than did intervention group caregivers, and control group patients scored lower on the QuIC than did control group caregivers.IMPLICATIONS: Social support played a significant role in enhancing comprehension and recall of consent form information among patients. (shrink)
Northoff provides a compelling argument supporting a kind of “double dissociation” of Parkinson's disease and catatonia. We discuss a related form of akinetic mutism linked to mesodiencephalic injuries and suggest an alternative to the proposed “horizontal” versus “vertical” modulation distinction. Rather than a “directional” difference in patterned neuronal activity, we propose that both disorders reflect hypersynchrony within typically interdependent but segregated networks facilitated by a common thalamic gating mechanism.
The application of neurostimulation techniques such as deep brain stimulation —often called a brain pacemaker for neurological conditions like Parkinson's disease —has generated “currents of hope.” Building on this hope, there is significant interest in applying neurostimulation to psychiatric disorders such as major depression and obsessive-compulsive disorder. These emerging neurosurgical practices raise a number of important ethical and social questions in matters of resource allocation, informed consent for vulnerable populations, and commercialization of research.
Leibniz' General Investigations, a group of memoranda on logical and methodological matters, remained unpublished until Couturat published the original Latin manuscript in 1903. Only after 1960 was a German translation made by F. Schmidt and an English translation by G. H. R. Parkinson. The present translation provides extensive reference notes to Leibniz' other manuscripts, and a commentary and notes to the text. In these respects it has some advantages over previous translations. The translation is clear although the work itself (...) is sometimes difficult to follow and the notes are most welcome. An introduction discusses the place of the General Investigations within the context of Leibniz' thought. With the interest in Leibniz' logical writings very strong at present, this new translation and commentary is most welcome.--R. H. K. (shrink)
The comparison of corporate social performance with corporate financial performance has been a popular field of study over the past 25 years. The results, while broadly conclusive of a positive relationship, are not entirely consistent. In addition, most of the previous studies have concentrated on large-scale cross-industry studies and often with a single variable for corporate social performance, in order to produce statistically significant results. This weakens the richness of understanding that might be obtained from a single industry study with (...) multiple social variables, which would also allow investigation of inter-relationships between individual and sub-sets of social performance measures and between individual and sub-sets of social performance and financial performance measures. There have also been criticisms that the results lack a rigorous theoretical basis, and the paper demonstrates clearly how stakeholder theory must form the basis for this area of research. Following a review of the literature this paper presents the initial findings from a study of the U.K. Supermarket industry which suggest that contemporaneous social and financial performance are negatively related, while prior-period financial performance is positively related with subsequent social performance. Positive relationships between both age and size of the company with social performance are also found. (shrink)
Attempts to extend the classical Hausdorff difference hierarchy to the case of partitions of a space to k > 2 subsets lead to non-equivalent notions. In a hope to identify the right extension we consider the extensions appeared in the literature so far: the limit-, level-, Boolean and Wadge hierarchies of k -partitions. The advantages and disadvantages of the four hierarchies are discussed. The main technical contribution of this paper is a complete characterization of the Wadge degrees of [ ¿ (...) ] º 2-measurable k -partitions of the Baire space. (shrink)
Whilst there is a growing volume of literature exploring the ethical implications of organisational change for HRM and the ethical aspects of certain HRM activities, there have been few published U.K. studies of how HR managers actually behave when faced with ethical dilemmas in their work. This paper seeks to enhance the foundations of such knowledge through an examination of the influence of organisational values on the ethical behaviour of Human Resource Managers within a sample of charities in the U.K. (...) and the Republic of Ireland. A qualitative research design is adopted utilising semi-structured interviews. Findings highlight ethical inconsistency in people management in the charity sector arising from the clear application of strong and explicit organisational values to external client groups but their limited influence on people management strategies and practices within the organisation. Many of the ethical issues faced by HRM professionals in both countries arise from this inconsistency. In their handling of ethical dilemmas, the HRM professionals exhibit a combination of a care ethic and a concern for justice but it is also clear that in situations of management intransigence, a desire to be conscience driven often gives way to a contingent approach. Whilst respondents considered it inappropriate for the HRM function to be the conscience of the organisation, it is seen to have a key role in providing management with advice on ethical action. However, the ability of HRM to influence ethical behaviour is highly dependent on the status of the function within the organisation. (shrink)
Since the beginning of the 20th Century to the present day, it has rarely been doubted that whenever formal aesthetic methods meet their iconological counterparts, the two approaches appear to be mutually exclusive. In reality, though, an ahistorical concept is challenging a historical analysis of art. It is especially Susanne K. Langer´s long-overlooked system of analogies between perceptions of the world and of artistic creations that are dependent on feelings which today allows a rapprochement of these positions. Krois’s insistence on (...) a similar point supports this analysis. - I - Unbestritten bis heute gilt, formwissenschaftliche und ikonologische Methoden scheinen sich grundsätzlich auszuschließen, da die ersteren auf ahistorischen und die letzteren auf historischen Grundlagen aufbauen. Dem entgegen soll mit diesem Beitrag gezeigt werden, wie insbesondere die Forschungen Susanne K. Langers und ergänzend diejenigen von John M. Krois eine Annäherung beider Positionen ermöglichen. (shrink)
Despite intense academic debate in the recent past over the use of ‘sham surgery’ control groups in research, there has been a recent resurgence in their use in the field of neurodegenerative disease. Yet the primacy of ethical arguments in favour of sham surgery controls is not yet established. Preliminary empirical research shows an asymmetry between the views of neurosurgical researchers and patients on the subject, while different ethical guidelines and regulations support conflicting interpretations. Research ethics committees faced with a (...) proposal involving sham surgery should be aware of its ethical complexities. An overview of recent and current placebo-controlled surgical trials in the field of Parkinson's Disease is provided here, followed by an analysis of the key ethical issues which such trials raise. (shrink)
I am a philosopher with Parkinson’s Disease. Over the past several years I’ve been trying to write about my situation. I wrote about how I was forced to face the disease. I described how the disease twists and distorts my world. Then I asked myself, as a philosophy writer and teacher, whether I could say anything that might help myself or others facing life with Parkinson’s? I found ideas in the ancient Stoics and expanded them with ideas about (...) time, coming up with suggestions for living as excellently as possible despite the disease. Looking at those suggestions, I realized how the special awareness, resolve, and attention I was suggesting would be eaten away by dementia, and I know that a majority of Parkinson’s patients face dementia if they survive long enough. What can philosophy say to me or any person whose self and philosophy are being erased? Writing about such issues has helped me deal with my situation, and maybe my essay might be useful for others dealing with decline. (shrink)
In this paper rejection systems for the “nonsense-logic” W and the k-valued implicational-negational sentential calculi of Sobociński are given. Considered systems consist of computable sets of rejected axioms and only one rejection rule: the rejection version of detachment rule.
We give two new characterizations of K-triviality. We show that if for all Y such that Ω is Y-random, Ω is -random, then A is K-trivial. The other direction was proved by Stephan and Yu, giving us the first titular characterization of K-triviality and answering a question of Yu. We also prove that if A is K-trivial, then for all Y such that Ω is Y-random, ≡LRY. This answers a question of Merkle and Yu. The other direction is immediate, so (...) we have the second characterization of K-triviality.The proof of the first characterization uses a new cupping result. We prove that if A≰LRB, then for every set X there is a B-random set Y such that X is computable from Y⊕A. (shrink)
K. Brad Wray’s new book is an excellent overview of the scientific realism debate, as well as a development of the state-of-the-art. Wray, whose views seem most strongly influenced by Bas van Fraassen and Thomas Kuhn, develops crucial aspects of the debate, such as the argument from underconsideration and the ability of anti-realism to explain the success of science. This book is clearly written, tightly argued, and well researched. I recommend it highly to all philosophers and students of philosophy interested (...) in scientific theory change or the scientific realism debate. (shrink)
The theoretical description of particle decay by a single particle theory requires the use of a probability density in time that is not present in conventional theories. The problem of single particle decay is consistently described here within the context of a single particle, relativistic dynamical theory. We derive experimentally testable differences between the standard model and Relativistic Dynamics for a two-state system: the neutral K-meson (K 0) system. We show that the estimate of mass difference between the two states (...) is theory dependent. (shrink)
Hiçbir bilim dalında, yazar, felsefe ve mantıkta yapabildiği kadarıyla, güvenilir araştırma sonuçlarını böylesine fütursuzca hiçe sayamaz. Bu durum için, Bay Coffey’in Mantık Bilimi gibi böyle bir kitabın yayınlanmasına borçluyuz: ve yalnızca, günümüzün pek çok mantıkçısının eserinin tipik bir örneği olarak, bu kitap saygıyı hak ediyor. Yazarın mantık anlayışı Skolastik filozoflarınki gibidir, ve onların bütün hatalarını yapıyor – elbette Aristoteles’e alışılageldik gönderilerle.. Yazar, modern matematiksel mantıkçıların büyük eserini hiç dikkate almamış – mantık konusunda bir ilerleme kaydeden eser, ancak astrolojisiz astronomi ve (...) simyasız kimya yapan bir şeyle karşılaştırılabilir. (shrink)
The discovery of induced pluripotent stem (iPS) cells in 2006 was heralded as a major breakthrough in stem cell research. Since then, progress in iPS cell technology has paved the way towards clinical application, particularly cell replacement therapy, which has refueled debate on the ethics of stem cell research. However, much of the discourse has focused on questions of moral status and potentiality, overlooking the ethical issues which are introduced by the clinical testing of iPS cell replacement therapy. First-in-human trials, (...) in particular, raise a number of ethical concerns including informed consent, subject recruitment and harm minimisation as well as the inherent uncertainty and risks which are involved in testing medical procedures on humans for the first time. These issues, while a feature of any human research, become more complex in the case of iPS cell therapy, given the seriousness of the potential risks, the unreliability of available animal models, the vulnerability of the target patient group, and the high stakes of such an intensely public area of science. Our paper will present a detailed case study of iPS cell replacement therapy for Parkinson's disease to highlight these broader ethical and epistemological concerns. If we accept that iPS cell technology is fraught with challenges which go far beyond merely refuting the potentiality of the stem cell line, we conclude that iPS cell research should not replace, but proceed alongside embryonic and adult somatic stem cell research to promote cross-fertilisation of knowledge and better clinical outcomes. (shrink)
Subjects enrolled in studies testing high risk interventions for incurable or progressive brain diseases may be vulnerable to deficiencies in informed consent, such as the therapeutic misconception. However, the definition and measurement of the therapeutic misconception is a subject of continuing debate. Our qualitative pilot study of persons enrolled in a phase I trial of gene transfer for Parkinson disease suggests potential avenues for both measuring and preventing the therapeutic misconception. Building on earlier literature on the topic, we developed (...) and tested an interview guide that focuses on how the subjects decided to participate, emphasizing the integration of subjects’ various statements that are relevant to assessing the therapeutic misconception, rather than evaluating them as isolated statements. The results indicate that a subject’s understanding of the purpose of research is best explored in juxtaposition to the subject’s motivation for participating. (shrink)
What is characteristic of being aParkinson’s patient? This article intends toanswer this question by means of an analysis ofnovels about people with Parkinson’s disease,personal accounts, and scientific publications.The texts were analyzed from anexistential-phenomenological perspective, usingan adapted version of the existential analysis.Being a Parkinson’s patient is apparentlycharacterized by an existential paradox: lifeappears simultaneously immobile andunpredictably whimsical. This may manifestitself in the person’s corporeality, in hisbeing-in-time and in-space, in his relating tothings and events, his life-world, and in hisbeing-together-with-others as an (...) individual.Finally, some specific characteristics of beinga Parkinson’s patient are described that may berelevant for purposes of adequate care, as isto be specified by further research. (shrink)
We study some metamathematical properties of various classicaland paraconsistent logical systems. In particular, we discuss the concept ofa k-transform of a formula and consider some of its applications.
Resumo Em 1747, John Wesley, spiritus rector do movimento metodista, publicou a primeira edição do seu guia medicinal Primitive Physic[k] . Qual era o seu propósito num mundo onde a academia real, herbalistas, curandeiros/as, exorcistas e charlatães competiam pela atenção da população? O artigo apresenta os diferentes grupos que atuaram, ou pretendiam atuar, em prol da saúde na Inglaterra do século 18, e compara o conteúdo do guia Primitive Physic[k] com suas propostas e estratégias terapêuticas. Conclua-se que uma parte significativa (...) do guia é composta por orientações da academia real de medicina, mas que sempre se favorecem remédios caseiros, com ingredientes acessíveis para as classes mais humildes. Quanto à chamada Spiritual Physick , menciona-se a oração como medida complementar, mas ignora-se plenamente a prática do exorcismo. Palavras-chave: John Wesley; saúde; Guia medicinal popular; Primitive Physic[k]; academia real de medicina; herbalismo; curandeirismo.In 1747, John Wesley, spiritus rector of the Methodist movement, published the first edition of his medical guide Primitive Physic[k] . What was its purpose in a world where the Royal Academy, herbalists, healers, exorcists and quacks competed for the attention of the population? The article introduces the different groups who promoted or pretended to promote health in 18th century England and compares the contents of the guide Primitive Physic[k] with their proposals and therapeutic strategies. The conclusion is that a significant portion of the guide consists of guidelines of the Royal Academy of Medicine, but that it always favors homemade remedies with ingredients available to humbler classes. In relation to the so called Spiritual Physick, prayer is mentioned as a complementary measure, but the practice of exorcism is totally ignored. Keywords: John Wesley; health; Popular Medicinal Guide; Primitive Physic[k]; Royal Academy of Medicine; herbalism; healers. (shrink)
.........................Turkish ....................... Çalışmanın konusu dindarlık eğilimi ile meslekî tükenmişlik arasındaki ilişkidir. Dindarlık eğilimine göre meslekî tükenmişlik düzeyinde herhangi bir farklılık olup olmadığı ise çalışmanın temel problemini oluşturmuştur. Bu bağlamda meslekî tükenmişlik düzeyini ve dindarlık eğilimini belirlemek için kolayda örnekleme yöntemiyle Gümüşhane il merkezindeki ilkokul, ortaokul ve liselerde görev yapan farklı branşlardaki öğretmenlerden bir örneklem grubu oluşturulmuştur. Elde edilen meslekî tükenmişlik ve dindarlık eğilimi verilerinden yola çıkarak bu iki değişkenin ilişkisi araştırılmıştır. Çalışmada Frekans, Bağımsız t-Testi, Tek Yönlü Varyans AnaliziANOVA testleri kullanılmıştır. (...) Bunun yanında hesaplanan değerleri ve elde edilen verileri değerlendirmek için SPSS (16.0) istatistik paket programı kullanılmıştır. Araştırma iki bölümden oluşmuştur. İlk bölümde dindarlık eğilimi ile meslekî tükenmişlik ilişkisine teorik bir yaklaşım sunulmuştur; meslekî tükenmişlik ve dindarlık kavramı, meslekî tükenmişlikle ilgili yurt içinde ve yurt dışında yapılan araştırmalar ve son olarak da meslekî tükenmişlik ile dindarlık eğilimi arasındaki ilişkiden bahsedilmiştir. İkinci bölümde uygulama kısmı, çalışmanın problemi ve alt problemleri, hipotezler, evren ve örneklem, kullanılan ölçekle ilgili sınırlıklar, çalışma bulgularının analizi, bulguların tartışılması, sonuçlar ve çalışmanın önerileri sunulmuştur. Çalışmanın sonuçlarına göre meslekî tükenmişlik puanları cinsiyet değişkenine göre farklılaşmazken, sosyo-ekonomik durum değişkenine göre anlamlı farklılık göstermiştir. Bunun yanında dindarlık eğilimine yönelik anket maddeleri ile meslekî tükenmişlik puanları arasında anlamlı düzeyde farklılaşmalara ulaşılmıştır. Sonuç olarak dindarlık eğiliminin meslekî tükenmişliğe etki eden faktörlerden biri olduğu tespit edilmiştir. -/- ...................................English ...................... Subject of this study is correlation of occupational burnout with the tendency of religiosity. Our main problem consists of that whether to be any differences in occupational burnout level according to the tendency of religiosity. In this context, it has been propounded that the levels of occupational burnout and tendency of religiosity of a sample group which consists of teachers chosen convenience sampling method from primary schools, secondary schools and high schools in Gümüşhane province. Based on the resulting occupational burnout and tendency of religiosity, investigated the correlation between these two variables. In the study the Frequency, Independent t-Test and One Way Variance Analysis-ANOVA tests were used and the evaluation of data and finding calculated values, SPSS (16.0) statistics software package were used. According to the results of the survey, the occupational burnout scores a differentiation has not been shown according to gender when has been established a significant difference according to socioeconomic status variable as independent variables. Besides, have been established a significant difference between tendency of religiosity of items and occupational burnout scale scores. The study consists of two main parts. In the first part, to provide a theoretical approach to the relationship of occupational burnout and tendency of religiosity; the concept of occupational bornout, the studies made on occupational burnout in domestic and abroad, and finally the relation of occupational burnout and tendency of religiosity have been mentioned. In the second part, considered as part of practice, the problem of the study and sub problems, hypothesis, population and sample, limitations information about the scale used in the study, analyzing the findings of the study, discussing the findings and conclusions and recommendations of the study have been presented. (shrink)
In this article I focus on some unduly neglected common-sense considerations supporting the view that one's evidence is the propositions that one knows. I reply to two recent objections to these considerations.
Orta Çağ’da, İslam düşüncesi içerisinde yazılmış olan İbn Sînâ’nın eş-Şifâ: İlahiyat’ı, Gazzâlî’nin Makâsıdu’l-Felâsife’si ve İbn Rüşd’ün, Aristoteles’in eserlerine yazmış olduğu şerhler gibi pek çok felsefî ve teolojik eser Latinceye çevrilmiştir. Söz konusu çeviri eserler vasıtasıyla, İslam düşüncesinde carî olan, Tanrı’nın tikelleri kendi zatlarında bilip bilmediği, Tanrı’nın zatı gereği fiilde bulunup bulunmadığı, din ve felsefenin uzlaşıp uzlaşmayacağı gibi tartışmalı pek çok mesele Batı’ya intikal etmiştir. Bunlara ilaveten Tanrı’nın mutlak kudretinin alanının ne olduğu sorunu da Batı düşüncesinde bilinir hale gelmiştir. Bu çalışmada, (...) “Tanrı mantıksal olarak mümkün olanı yapabilir ve bu durum Tanrı’nın mutlak kudretine halel getirmez” anlayışının Latin Batı dünyasına İbn Sînâ’nın eş-Şifâ’sı ve Gazzâlî’nin Makâsıdu’l-Felâsife’sinin çevrileri vasıtasıyla intikal ettiği ortaya konulmaya çalışılmıştır. Tespit edebildiğimiz kadarıyla, Gazzâlî’nin Makâsıdu’l-Felâsife’de bu konuya ilişkin serdettiği fikirler ile Hristiyan teolog/düşünür Thomas Aquinas’ın fikirleri arasında önemli ölçüde benzerlik söz konusudur. Söz konusu benzerlik temele alınarak, Thomas Aquinas’ın bu hususta İslam düşüncesinden beslendiğini söylemek kuvvetle muhtemeldir. (shrink)