The competing expressions of ideology flooding the contemporary political landscape have taken a turn toward the absurd. The Radiance Foundation’s recent anti-abortion campaign targeting African-American women, including a series of billboards bearing the slogan “The most dangerous place for an African-American child is in the womb”, is just one example of political "discourse" that is both infuriating and confounding. Discourse with these features – problematic intelligibility, disinterest in the truth, and inflammatory rhetoric – has become increasingly common in politics, the (...) press, and even the arguments made by ordinary folk. It is often criticized for its falsehood or its hurtfulness; however, these critiques tend to miss its pernicious potential. This essay characterizes this insidious discourse as purposeful nonsense. Part of the way that purposeful nonsense functions, we argue, relies on taking advantage of harmful stereotypes and denigrating narratives that are already present in our culture. Purposeful nonsense both draws upon harmful ideology and fortifies it. The effect is that members of oppressed social groups are confronted with disparaging ideology, while its authors are free to deny responsibility for it. Black feminist and intersectional analysis – particularly in the discussion of race, abortion, and reproductive justice – are useful in identifying and criticizing the harmful subtext in the Radiance Foundation’s billboard campaign. The notion of purposeful nonsense serves to extend the reach of these criticisms. Purposeful nonsense – disguised as merely logically confused discourse – is a key factor in maintaining an oppressive and unjust society; however, feminist, black feminist, and intersectional analysis contextualizes purposeful nonsense, potentially disrupting its harmful influence. We conclude that purposeful nonsense employs a variation on stereotype threat, a phenomenon in which being reminded of negative stereotypes about one’s social group causes stereotypical performance failures. We suggest that the notion of stereotype threat combined with intersectional analysis offers a fruitful avenue along which research on this sort of discourse might be expanded. (shrink)

It has generally been observed that cells grow to a certain size before they divide. In the last few years, the PI3K signal transduction pathway has emerged as one of the main signaling routes utilized by cells to control their increase in size. Here we focus on two components of this pathway, PKB and S6K, and briefly review the experiments that initially uncovered their roles in cell size control. In addition, we discuss a number of recent observations suggesting that the (...) generic models used to describe this pathway to date may have been oversimplified. Indeed, recent observations in Drosophila and mouse support a more complex interaction between these signaling components in development. Finally, we have utilized two contemporary studies involving PKB‐ and S6K‐deficient mice as a paradigm to underscore the importance of cell size and to accurately delineate the connections between signaling pathways for human disease, such as diabetes mellitus. BioEssays 24:65–71, 2002. © 2002 John Wiley & Sons, Inc. (shrink)

Spatio-temporal neuro-dynamics is a quickly developing field of brain research and Tsuda's work is a significant contribution toward establishing theoretical foundations in this area. It is conceivable that the fragmented attractor landscapes and dynamical memory patterns identified earlier in various K-sets are biologically plausible manifestations of attractor ruins, chaotic itinerancy, and Cantor encoding as applied to sensory information processing.

Subjective experience suggests that we continuously observe, perceive, and evaluate the environment as we make decisions and intentional actions. The percept of continuity of our cognition, however, is an illusion. In the past decades, ample experimental evidence has been accumulated indicating that cognition evolves through a sequence of discontinuities and transients, and there are discernable neural processes correlating with the cognitive sequences. These discontinuities are crucial in the intentional action-perception cycle, as they mark the cognitive 'aha' moment of deep understanding (...) and conscious insight. Walter Freeman developed a hierarchical model to describe these physiological findings, culminating in the cinematic theory of cognition. Following the traditions of metastability, transient neurodynamics, and brain chaos, discontinuities are described as phase transitions in the cortical neuropil. This approach not only leads to deep theoretical insights of neural correlates of cognition and consciousness, but it also helps to form a conceptual framework to create artificially intelligent devices that are in harmony with humans and serve peaceful development of humanity. (shrink)

Machiavelli’s The Prince is an important modern work of political science, but it is also one that has been often misinterpreted by students and scholars. This work helps the reader to better understand Machiavelli’s consequentialism and realism by using examples from modern films and television series to illustrate his messages.

A unifing theory of spatiotemporal brain dynamics should incorporate multiple spatial and temporal scales. Between the microscopic (local) and macroscopic (global) components proposed by Nunez, mesoscopic (intermediate-range) elements should be integral parts of models. The corresponding mathematical formalism requires tools of nonlinear dynamics and the use of aperiodic (chaotic) attractors. Some relations between local-mesoscopic and mesoscopic-global components are outlined.

Objective correlates—behavioral, functional, and neural—provide essential tools for the scientific study of consciousness. But reliance on these correlates should not lead to the ‘fallacy of misplaced objectivity’: the assumption that only objective properties should and can be accounted for objectively through science. Instead, what needs to be explained scientifically is what experience is intrinsically— its subjective properties—not just what we can do with it extrinsically. And it must be explained; otherwise the way experience feels would turn out to be magical (...) rather than physical. We argue that it is possible to account for subjective properties objectively once we move beyond cognitive functions and realize what experience is and how it is structured. Drawing on integrated information theory, we show how an objective science of the subjective can account, in strictly physical terms, for both the essential properties of every experience and the specific properties that make particular experiences feel the way they do. (shrink)

The selection of nineteenth-century Arabic texts on medical education, medicine and health demonstrates the significant link between the revival of the Arabic language and literary culture of the nineteenth century, known as thenahda, and the introduction of medical education to the Ottoman Empire. These include doctor Ibrahim al-Najjar's autobiographical account of his studies in Cairo (1855), an article by doctor Amin Abi Khatir advising on the health and care of infants (1877), questions and answers in the major popular Arabic journalsal-Hilalandal-Muqtataf(1877–1901) (...) and an article about a new tuberculosis treatment by doctor Anisa Sayba‘a (1903). Taken together they contribute to our understanding of the bottom-up production, reproduction and reception of global scientific knowledge, as well as to a social and intellectual history of science. We argue that the engagement with science during thenahdawas a multi-vocal and dialogical process, in which doctors and patients, journal editors and their readers, negotiated the implications of scientific knowledge for their own lives and their own society. The texts of the original documents and their translations can be found in the supplementary material tab athttps://doi.org/10.1017/S0007087422000413. (shrink)

Fix an integer $r \ge 3$. We consider metric spaces on n points such that the distance between any two points lies in $\left\{ {1, \ldots,r} \right\}$. Our main result describes their approximate structure for large n. As a consequence, we show that the number of these metric spaces is $\left\lceil {{{r + 1} \over 2}} \right\rceil ^{\left + o\left}.$Related results in the continuous setting have recently been proved by Kozma, Meyerovitch, Peled, and Samotij [34]. When r is even, our (...) structural characterization is more precise and implies that almost all such metric spaces have all distances at least $r/2$. As an easy consequence, when r is even, we improve the error term above from $o\left$ to $o\left$, and also show a labeled first-order 0-1 law in the language ${\cal L}_r $, consisting of r binary relations, one for each element of $[r]$. In particular, we show the almost sure theory T is the theory of the Fraïssé limit of the class of all finite simple complete edge-colored graphs with edge colors in $\left\{ {r/2, \ldots,r} \right\}$.Our work can be viewed as an extension of a long line of research in extremal combinatorics to the colored setting, as well as an addition to the collection of known structures that admit logical 0-1 laws. (shrink)

Resumen. En el presente análisis se exponen las bases del clásico debate entre Richard Clark y Robert Kozma, autores reconocidos en el campo de Tecnología Instruccional y la Educación a Distancia por la relevancia de sus aportaciones; a partir del argumento inicial presentado por Richard Clark en 1983 contenido en su artículo denominado Reconsidering research on learning from media; dónde describe evidencias suficientes que apoyan su opinión respecto a que los medios instruccionales no ejercen influencia alguna en el nivel de (...) aprovechamiento de los estudiantes durante el proceso de enseñanza-aprendizaje.Palabras claves. Tecnología instruccional, educación a distancia, medios, aprendizaje, enseñanza.. This analysis sets out the basis of the classic debate between Richard Clark and Robert Kozma, known authors in the field of Instructional Technology and Distance Education for the relevance of their contributions, from the initial argument presented by Richard Clark in 1983 contained in his article entitled Reconsidering research on learning from media; in which he describes sufficient evidences supporting his opinion that instructional media have no influence on the level of student achievement in the teaching-learning process.Keywords. Instructional technology, distance education, media, learning, teaching. (shrink)