41 found
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  1.  29
    The Birth of the Empirical Turn in Bioethics.Pascal Borry, Paul Schotsmans & Kris Dierickx - 2005 - Bioethics 19 (1):49–71.
  2.  23
    What is the Role of Empirical Research in Bioethical Reflection and Decision-Making? An Ethical Analysis.Pascal Borry, Paul Schotsmans & Kris Dierickx - 2004 - Medicine, Health Care and Philosophy 7 (1):41-53.
    The field of bioethics is increasingly coming into contact with empirical research findings. In this article, we ask what role empirical research can play in the process of ethical clarification and decision-making. Ethical reflection almost always proceeds in three steps: the description of the moral question,the assessment of the moral question and the evaluation of the decision-making. Empirical research can contribute to each step of this process. In the description of the moral object, first of all, empirical research has a (...)
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  3.  49
    Paper: The Return of Individual Research Findings in Paediatric Genetic Research.Kristien Hens, Herman Nys, Jean-Jacques Cassiman & Kris Dierickx - 2011 - Journal of Medical Ethics 37 (3):179-183.
    The combination of the issue of return of individual genetic results/incidental findings and paediatric biobanks is not much discussed in ethical literature. The traditional arguments pro and con return of such findings focus on principles such as respect for persons, autonomy and solidarity. Two dimensions have been distilled from the discussion on return of individual results in a genetic research context: the respect for a participant’s autonomy and the duty of the researcher. Concepts such as autonomy and solidarity do not (...)
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  4.  15
    Empirical Ethics: A Challenge to Bioethics.Pascal Borry, Paul Schotsmans & Kris Dierickx - 2004 - Medicine, Health Care and Philosophy 7 (1):1-3.
    The field of bioethics is increasingly coming into contact with empirical research findings. In this article, we ask what role empirical research can play in the process of ethical clarification and decision-making. Ethical reflection almost always proceeds in three steps: the description of the moral question,the assessment of the moral question and the evaluation of the decision-making. Empirical research can contribute to each step of this process. In the description of the moral object, first of all, empirical research has a (...)
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  5. Benefit Sharing: An Exploration on the Contextual Discourse of a Changing Concept. [REVIEW]Bege Dauda & Kris Dierickx - 2013 - BMC Medical Ethics 14 (1):36.
    The concept of benefit sharing has been a topical issue on the international stage for more than two decades, gaining prominence in international law, research ethics and political philosophy. In spite of this prominence, the concept of benefit sharing is not devoid of controversies related to its definition and justification. This article examines the discourses and justifications of benefit sharing concept.
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  6.  8
    Amnestic MCI Patients’ Perspectives Toward Disclosure of Amyloid PET Results in a Research Context.Gwendolien Vanderschaeghe, Jolien Schaeverbeke, Rik Vandenberghe & Kris Dierickx - 2017 - Neuroethics 10 (2):281-297.
    BackgroundResearchers currently are not obligated to share individual research results with participants. This non-disclosure policy has been challenged on the basis of participants’ rights to be aware and in control of their personal medical information. Here, we determined how patients view disclosure of research PET results of brain amyloid and why they believe it is advantageous or disadvantageous to disclose.MethodAs a part of a larger diagnostic trial, we conducted semi-structured interviews with patients with amnestic Mild Cognitive Impairment. Participants had the (...)
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  7.  35
    Evidence‐Based Medicine and its Role in Ethical Decision‐Making.Pascal Borry, Paul Schotsmans & Kris Dierickx - 2006 - Journal of Evaluation in Clinical Practice 12 (3):306-311.
  8.  12
    Stakeholders’ Views on Early Diagnosis for Alzheimer’s Disease, Clinical Trial Participation and Amyloid PET Disclosure: A Focus Group Study.Gwendolien Vanderschaeghe, Rik Vandenberghe & Kris Dierickx - 2019 - Journal of Bioethical Inquiry 16 (1):45-59.
    Detection of Alzheimer’s disease in an early stage is receiving increasing attention for a number of reasons, such as the failure of drug trials in more advanced disease stages, the demographic evolution, the financial impact of AD, and the approval of amyloid tracers for clinical use. Five focus group interviews with stakeholders were conducted.. The verbatim transcripts were analysed via the Nvivo 11 software. Most stakeholder groups wanted to know their own amyloid PET scan result. However, differences occurred between FGs: (...)
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  9. Review of National Research Ethics Regulations and Guidelines in Middle Eastern Arab Countries. [REVIEW]Ghiath Alahmad, Mohammad Al-Jumah & Kris Dierickx - 2012 - BMC Medical Ethics 13 (1):34-.
    Background Research ethics guidelines are essential for conducting medical research. Recently, numerous attempts have been made to establish national clinical research documents in the countries of the Middle East. This article analyzes these documents. Methods Thirteen Arab countries in the Middle East were explored for available national codes, regulations, and guidelines concerning research ethics, and 10 documents from eight countries were found. We studied these documents, considering the ethical principles stated in the Declaration of Helsinki, the Council for International Organizations (...)
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  10.  5
    Scientists Still Behaving Badly? A Survey Within Industry and Universities.Simon Godecharle, Steffen Fieuws, Ben Nemery & Kris Dierickx - 2018 - Science and Engineering Ethics 24 (6):1697-1717.
    Little is known about research misconduct within industry and how it compares to universities, even though a lot of biomedical research is performed by–or in collaboration with–commercial entities. Therefore, we sent an e-mail invitation to participate in an anonymous computer-based survey to all university researchers having received a biomedical research grant or scholarship from one of the two national academic research funders of Belgium between 2010 and 2014, and to researchers working in large biomedical companies or spin-offs in Belgium. The (...)
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  11.  18
    Author, Contributor or Just a Signer? A Quantitative Analysis of Authorship Trends in the Field of Bioethics.Pascal Borry, Paul Schotsmans & Kris Dierickx - 2006 - Bioethics 20 (4):213–220.
  12.  12
    Review of the Ethical Issues of a Biomarker-Based Diagnoses in the Early Stage of Alzheimer’s Disease. [REVIEW]Gwendolien Vanderschaeghe, Kris Dierickx & Rik Vandenberghe - 2018 - Journal of Bioethical Inquiry 15 (2):219-230.
    Background: Today, many healthcare or dementia organizations, clinicians, and companies emphasize the importance of detection of Alzheimer’s disease in an early phase. This idea has gained considerable momentum due to the development of biomarkers, the recent FDA and EMA approval of three amyloid tracers, and the failure of a number of recent therapeutic trials conducted in the early dementia phase. On the one hand, an early etiological diagnosis can lead to early and more efficacious intervention. On the other hand, it (...)
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  13.  10
    Differing Perceptions Concerning Research Integrity Between Universities and Industry: A Qualitative Study.Simon Godecharle, Benoit Nemery & Kris Dierickx - 2018 - Science and Engineering Ethics 24 (5):1421-1436.
    Despite the ever increasing collaboration between industry and universities, the previous empirical studies on research integrity and misconduct excluded participants of biomedical industry. Hence, there is a lack of empirical data on how research managers and biomedical researchers active in industry perceive the issues of research integrity and misconduct, and whether or not their perspectives differ from those of researchers and research managers active in universities. If various standards concerning research integrity and misconduct are upheld between industry and universities, this (...)
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  14.  14
    Health, Human Right, and Health Inequalities: Alternative Concepts in Placing Health Research as Justice for Global Health.Bege Dauda & Kris Dierickx - 2012 - American Journal of Bioethics 12 (11):42-44.
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  15.  13
    Regulating Trust in Pediatric Clinical Trials.Wim Pinxten, Herman Nys & Kris Dierickx - 2008 - Medicine, Health Care and Philosophy 11 (4):439-444.
    The participation of minors in clinical trials is essential to provide safe and effective medical care to children. Because few drugs have been tested in children, pediatricians are forced to prescribe medications off-label with uncertain efficacy and safety. In this article, we analyze how the enrollment of minors in clinical trials is negotiated within relationships of mutual trust between clinicians, minors, and their parents. After a brief description of the problems associated with involving minors in clinical research, we consider how (...)
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  16.  15
    Is Tissue Engineering a New Paradigm in Medicine? Consequences for the Ethical Evaluation of Tissue Engineering Research.Leen Trommelmans, Joseph Selling & Kris Dierickx - 2009 - Medicine, Health Care and Philosophy 12 (4):459-467.
    Ex-vivo tissue engineering is a quickly developing medical technology aiming to regenerate tissue through the introduction of an ex-vivo created tissue construct instead of restoring the damaged tissue to some level of functionality. Tissue engineering is considered by some as a new medical paradigm. We analyse this claim and identify tissue engineering’s fundamental characteristics, focusing on the aim of the intervention and on the complexity and continuity of the process. We inquire how these features have an impact not only on (...)
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  17.  18
    Standard of Care in Clinical Research with Human Tissue Engineered Products (Hteps).Leen Trommelmans & Kris Dierickx - 2009 - American Journal of Bioethics 9 (3):44 – 45.
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  18.  25
    What Do Islamic Institutional Fatwas Say About Medical and Research Confidentiality and Breach of Confidentiality?Ghiath Alahmad & Kris Dierickx - 2012 - Developing World Bioethics 12 (2):104-112.
    Protecting confidentiality is an essential value in all human relationships, no less in medical practice and research.1 Doctor-patient and researcher-participant relationships are built on trust and on the understanding those patients' secrets will not be disclosed.2 However, this confidentiality can be breached in some situations where it is necessary to meet a strong conflicting duty.3Confidentiality, in a general sense, has received much interest in Islamic resources including the Qur'an, Sunnah and juristic writings. However, medical and research confidentiality have not been (...)
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  19.  20
    Ethical Issues Surrounding the Provider Initiated Opt – Out Prenatal HIV Screening Practice in Sub – Saharan Africa: A Literature Review.Luchuo Engelbert Bain, Kris Dierickx & Kristien Hens - 2015 - BMC Medical Ethics 16 (1):1-12.
    BackgroundPrevention of mother to child transmission of HIV remains a key public health priority in most developing countries. The provider Initiated Opt – Out Prenatal HIV Screening Approach, recommended by the World Health Organization lately has been adopted and translated into policy in most Sub – Saharan African countries. To better ascertain the ethical reasons for or against the use of this approach, we carried out a literature review of the ethics literature.MethodsPapers published in English and French Languages between 1990 (...)
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  20.  19
    Access to Human Tissues for Research and Product Development.Jean‐Paul Pirnay, Etienne Baudoux, Olivier Cornu, Alain Delforge, Christian Delloye, Johan Guns, Ernst Heinen, Etienne Van den Abbeel, Alain Vanderkelen, Caroline Van Geyt, Ivan van Riet, Gilbert Verbeken, Petra De Sutter, Michiel Verlinden, Isabelle Huys, Julian Cockbain, Christian Chabannon, Kris Dierickx, Paul Schotsmans, Daniel De Vos, Thomas Rose, Serge Jennes & Sigrid Sterckx - unknown
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  21.  13
    Ethical Signposts for Clinical Geneticists in Secondary Variant and Incidental Finding Disclosure Discussions.Gabrielle M. Christenhusz, Koenraad Devriendt, Hilde Van Esch & Kris Dierickx - 2015 - Medicine, Health Care and Philosophy 18 (3):361-370.
    While ethical and empirical interest in so-called secondary variants and incidental findings in clinical genetics contexts is growing, critical reflection on the ethical foundations of the various recommendations proposed is thus far largely lacking. We examine and critique the ethical justifications of the three most prominent disclosure positions: briefly, the clinical geneticist decides, a joint decision, and the patient decides. Subsequently, instead of immediately developing a new disclosure option, we explore relevant foundational ethical values and norms, drawing on the normative (...)
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  22.  14
    Double Trouble: Preventive Genomic Sequencing and the Case of Minors.Kristien Hens & Kris Dierickx - 2015 - American Journal of Bioethics 15 (7):30-31.
  23.  10
    How Do Chinese Universities Address Research Integrity and Misconduct? A Review of University Documents.Nannan Yi, Benoit Nemery & Kris Dierickx - 2019 - Developing World Bioethics 19 (2):64-75.
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  24.  13
    One Size That Could Fit All: IRBs Joint Review Collaboration as the Key to Addressing the Challenges of Multinational Research Review Involving Resource-Poor Countries.Bege Dauda & Kris Dierickx - 2014 - American Journal of Bioethics 14 (5):15-17.
  25.  8
    Empirical Ethics: The “Missing Link” in Incidental Findings Recommendations.Gabrielle Christenhusz, Koenraad Devriendt & Kris Dierickx - 2014 - American Journal of Bioethics 14 (3):31-33.
  26.  3
    Christelijke Ethiek En De Geest Van Het KapitalismeChristian Ethics And The Spirit Of Capitalism.Kris Dierickx - 1996 - Bijdragen 57 (2):158-188.
    Max Weber's century old thesis on christian ethics and the spirit of capitalism, has been the object of an endless discussion. This has much to do with the interest of the author: Weber was neither intrigued by the fact of a connection between protestantism and capitalism, nor by the influence of Calvinism on the development of the modern capitalism. His interest, however, was exclusively focused on the question 'how can the relation between protestant ethic and capitalism be conceived and reconstructed'. (...)
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  27.  12
    Amnestic MCI Patients’ Perspectives on Volunteer Participation in a Research Context.Gwendolien Vanderschaeghe, Jolien Schaeverbeke, Rik Vandenberghe & Kris Dierickx - 2017 - Journal of Clinical Research and Bioethics 8 (3).
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  28.  18
    Potential Pitfalls in the Evaluation of Ethics Consultation: The Case of Ethical Counseling.Alma Linkeviciute, Kris Dierickx, Virginia Sanchini & Giovanni Boniolo - 2016 - American Journal of Bioethics 16 (3):56-57.
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  29.  13
    Expanding Social Media Use Recommendations to Global, Multicentred, Industry Run Clinical Trials.Alma Linkeviciute & Kris Dierickx - 2017 - American Journal of Bioethics 17 (3):23-24.
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  30.  17
    What Do the Various Principles of Justice Mean Within the Concept of Benefit Sharing?Bege Dauda, Yvonne Denier & Kris Dierickx - 2016 - Journal of Bioethical Inquiry 13 (2):281-293.
    The concept of benefit sharing pertains to the act of giving something in return to the participants, communities, and the country that have participated in global health research or bioprospecting activities. One of the key concerns of benefit sharing is the ethical justifications or reasons to support the practice of the concept in global health research and bioprospecting. This article evaluates one of such ethical justifications and its meaning to benefit sharing, namely justice. We conducted a systematic review to map (...)
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  31.  23
    Christelijke Ethiek En De Geest Van Het Kapitalisme.Kris Dierickx - 1996 - Bijdragen 57 (2):158-188.
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  32.  18
    De invloed van het'Humane Genome Project'op de concepten van ziekte en gezondheid.Kris Dierickx - 2000 - Wijsgerig Perspectief 40:132-137.
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  33.  17
    The Origin and Emergence of Empirical Ethics.Pascal Borry, Paul Schotsmans & Kris Dierickx - 2008 - In Guy Widdershoven (ed.), Empirical Ethics in Psychiatry. Oxford University Press. pp. 37--50.
  34.  5
    Integrity in Biomedical Research: A Systematic Review of Studies in China.Nannan Yi, Benoit Nemery & Kris Dierickx - 2019 - Science and Engineering Ethics 25 (4):1271-1301.
    Recent empirical evidence has demonstrated that research misconduct occurs to a substantial degree in biomedical research. It has been suggested that scientific integrity is also of concern in China, but this seems to be based largely on anecdotal evidence. We, therefore, sought to explore the Chinese situation, by making a systematic review of published empirical studies on biomedical research integrity in China. One of our purposes was also to summarize the existing body of research published in Chinese. We searched the (...)
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  35.  18
    De Concepten Ziekte En Gezondheid in Het Licht Van de Normativiteitsvraag.Kris Dierickx - 2006 - Tijdschrift Voor Filosofie 68 (2):231 - 250.
    In classical speculation on medical matters health is conceived of as a bodily statewhich is in accordance with Nature. It is a state of natural balance in the mixture (complexio) of the primary qualities of the human body. Although few of the details in theancient natural philosophy and the Galenic philosophy of health have survived, it is important to note that two of the ancient ideas still influence the thoughts: the idea ofa balance between opposing elements or forces, and, in (...)
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  36.  7
    Viewing Benefit Sharing in Global Health Research Through the Lens of Aristotelian Justice.Bege Dauda & Kris Dierickx - 2017 - Journal of Medical Ethics 43 (6):417-421.
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  37.  9
    Voortplantings Gericht Klonen.Bart Hansen, Kris Dierickx & Paul Schotsmans - 2004 - Bijdragen 65 (2):170-188.
    In this article we first clarify the technological possibilities in an Age of Biological Control. Secondly we offer a short overview of some major international statements on reproductive cloning. Since a careful use of terminology will help public policy, we opt for a clarification of the means and purposes of human cloning in a third paragraph. Fourthly, we summarize the main arguments against human reproductive cloning from a bio-ethical point of view. The main objective is however the analysis of the (...)
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  38.  14
    Ethical and Regulatory Issues in Pediatric Research Supporting the Non-Clinical Application of Fmr Imaging.Wim Pinxten, Herman Nys & Kris Dierickx - 2009 - American Journal of Bioethics 9 (1):21 – 23.
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  39.  5
    Confidentiality, Informed Consent, and Children’s Participation in Research Involving Stored Tissue Samples: Interviews with Medical Professionals From the Middle East.Ghiath Alahmad, Mohammed Al Jumah & Kris Dierickx - 2015 - Narrative Inquiry in Bioethics 5 (1):53-66.
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  40.  2
    Informed Consent in Children and Young People: An Introduction.Pascal Borry, Louise Stultiëns, Herman Nys & Kris Dierickx - unknown
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  41. Ethical Aspects of Genetic Testing.Kris Dierickx - 2002 - In Chris Gastmans (ed.), Between Technology and Humanity: The Impact of Technology on Health Care Ethics. Leuven University Press.
     
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