Generalized anxiety disorder (GAD) is characterized by excessive and uncontrollable worry about everyday life. Prior neuroimaging studies have demonstrated that GAD is associated with disruptions in specific brain regions; however, little is known about the global functional connectivity maps in adolescents with GAD. Here, first-episode, medication-naive, adolescent GAD patients ( N = 36) and healthy controls ( N = 28) (HCs) underwent resting-state functional MRI (R-fMRI) and completed a package of questionnaires to assess clinical symptoms. Functional connectivity strength and seed-based (...) functional connectivity were employed to investigate the functional connectivity architecture. GAD patients showed reduced functional connectivity strength in right supramarginal gyrus (SMG) and right superior parietal gyrus (SPG) compared with HCs. Further seed-based functional connectivity analysis revealed that GAD patients displayed decreased functional connectivity between right SMG and left fusiform gyrus, inferior temporal gyrus, parahippocampal gyrus, bilateral precuneus and cuneus, and between right SPG and bilateral supplementary motor area and middle cingulate gyrus, as well as between the SMG-based network and the SPG-based network. Moreover, the disrupted intra-network connectivity (i.e., the SMG-based network and the SPG-based network) and inter-network connectivity between the SMG-based network and the SPG-based network accounted for 25.5% variance of the State and Trait Anxiety Inventory (STAI) and 39.5% variance of the trait subscale of STAI. Our findings highlight the abnormal functional architecture in the SMG-based network and the SPG-based network in GAD, providing novel insights into the pathological mechanisms of this disorder. (shrink)

1. Pulgyo rŭl chŏmke hanŭn kil -- 2. Kisang ŭi chilmun kwa ch'ŏnoe ŭi tappyŏn.

An inclusive vision of mathematics-- its beauty, its humanity, and its power to build virtues that help us all flourish. For mathematician Francis Su, a society without mathematical affection is like a city without museums. To miss out on mathematics is to live without experiencing some of humanity's most beautiful ideas. In this profound book, written for a diverse audience but especially for those disenchanted by their past experiences, an award-winning mathematician and educator weaves personal reflections, puzzles, and stories to (...) show how mathematics meets basic human desires and cultivates virtues essential for human flourishing. Readers will explore mathematical concepts-- and see how mathematical thinking can even fulfill such longings as for love, play, freedom, justice, and community. Some lessons come from those who have struggled, including philosopher Simone Weil, whose own mathematical contributions were overshadowed by her brother's, and Christopher Jackson, who discovered mathematics as an inmate in a federal prison. Christopher Jackson's letters to the author appear throughout the book and show how this intellectual pursuit can-- and must-- be open to all. (shrink)

Kwŏnil chʻŏn. Kibon wŏlli pʻyŏn -- kwŏni chi. Chŭksa ihwa pʻyŏn -- kwŏnsam in. Pulcha haengdŭng pʻyŏn.

Jaina philosophical treatise with a Sanskrit commentary of Hemacandra Sūri, 12th cent.

Hanno Su entwickelt den Rahmen einer erziehungswissenschaftlichen Bildungstheorie, der Bildung über den differenziellen Wissensbezug pädagogischer Kommunikation fasst. Dadurch wird die Frage ins Zentrum gerückt, wie eine ausdrücklich erziehungstheoretische Problematisierung von Bildung sich gegenüber der herkömmlichen bildungstheoretischen Problematisierung von Erziehung abhebt. Anlass dieses Aufrisses ist eine Verwunderung darüber, dass hinsichtlich der Verschränkung von Erziehung und Bildung auch in der Erziehungswissenschaft vorwiegend individual- bzw. subjekttheoretische Rahmungen der Bildungstheorie genutzt werden, anstatt sich etwa mit sozialtheoretischen Rahmungen der Erziehungstheorie als erziehungswissenschaftliche Bildungstheorie in Form (...) zu bringen. (shrink)

1. Yu Hyŏng-wŏn ŭi ppuri wa Pan'gyehak ŭl nonhada -- 1.1. Pan'gye Yu Hyŏng-wŏn kagye punsŏk -- 1.2. Chiyŏkhak ŭrosŏ Pan'gyehak yŏn'gu -- 2. Pan'gye Sŏnsaeng palchach'wi rŭl ch'aja kada -- 2.1. Sirhak ŭi mek'a, Puan Uban-dong -- 2.2. Pan'gye Sŏnsaeng i namgin palchach'wi -- 2.3. Puan chiyŏk Yugyo munhwa yusan ŭi hyŏnhwang kwa kwaje -- 3. Pan'gye Sŏnsaeng ŭl kirida -- 3.1. Puan Tongnim Sŏwŏn ŭi kŏllip kwa pyŏnch'ŏn e taehan yŏn'gu -- 3.2. Tŏkch'on Yang Tŭk-chung ŭi kagye wa (...) ch'usung e kwanhan yŏn'gu -- 3.3. Hong Kye-hŭi Kyŏngseron ŭi chaejijŏk kiban. (shrink)