This article discusses experimentation in the context of sixteenth-century natural history, or natural science as I prefer to call it here. It uses predominantly textual sources, many of them manuscript letters, from different European countries, mainly Italy, the Low Countries, France and Germany-Austria. The focus is on the practice of experimentation and its documentation, partly because I proceed from the assumption that the investigation of living nature did not necessarily entail the same type of experimentation as contempo­rary alchemy, pharmacy, or (...) medicine, although all these domains of knowledge and their practitioners overlapped. The subject matter to some extent imposed its own rules. The first part of this essay analyses experimentation in the garden, which often combined practical purposes with research ones. The second and third parts discuss experimentation with both plants and animals that originated in more general questions or led to more wide-ranging conclusions about natural phenomena. The final section discusses the links with natural philosophy in these different types of experimentation in natural science, and addresses the possible implications for the concept of experimentation itself in the period shortly before the ”new science” of the seventeenth century. (shrink)

This article addresses the role of science and science advisory bodies in modeling practices for the support of policy-making procedures in the Netherlands in the field of health care. The authors show, based on a detailed investigation of a prestigious interdisciplinary modeling project in which an economic care model was developed for governmental use, that science advisory bodies are entangled with the policy actors they advise in what we call boundary configurations. Boundary configurations are strongly situated interconnections between science advisory (...) institutes and policy institutions that share a specific approach to problem definitions and methods and that are embedded in specific social, discursive, and material elements. Importantly, as the case study shows, such boundary configurations shape the kind of science, and related, the kind of social and political theories about the world, that is effectuated in modeling practices. In this case study, the boundary configuration in which economic experts and policy makers participated contributed to the articulation of health care in terms of a market-based policy program for the health care sector. (shrink)

ArgumentThis article studies the roles three science-based models play in Dutch policy and decision making processes. Key is the interaction between model construction and environment. Their political and scientific environments form contexts that shape the roles of models in policy decision making. Attention is paid to three aspects of the wider context of the models: a) the history of the construction process; b) the political and scientific environments; and c) the use in policy processes over longer periods of time. Models (...) are more successfully used when they are constructed in astablepolitical and scientific environment. Stability and certainty within a scientific field seems to be a key predictor for the usefulness of models for policy making. The economic model is more disputed than the ecology-based model and the model that has its theoretical foundation in physics and chemistry. The roles models play in policy processes are too complex to be considered as straightforward technocratic powers. (shrink)

BackgroundPreprint usage is growing rapidly in the life sciences; however, questions remain on the relative quality of preprints when compared to published articles. An objective dimension of quality that is readily measurable is completeness of reporting, as transparency can improve the reader’s ability to independently interpret data and reproduce findings.MethodsIn this observational study, we initially compared independent samples of articles published in bioRxiv and in PubMed-indexed journals in 2016 using a quality of reporting questionnaire. After that, we performed paired comparisons (...) between preprints from bioRxiv to their own peer-reviewed versions in journals.ResultsPeer-reviewed articles had, on average, higher quality of reporting than preprints, although the difference was small, with absolute differences of 5.0% [95% CI 1.4, 8.6] and 4.7% [95% CI 2.4, 7.0] of reported items in the independent samples and paired sample comparison, respectively. There were larger differences favoring peer-reviewed articles in subjective ratings of how clearly titles and abstracts presented the main findings and how easy it was to locate relevant reporting information. Changes in reporting from preprints to peer-reviewed versions did not correlate with the impact factor of the publication venue or with the time lag from bioRxiv to journal publication.ConclusionsOur results suggest that, on average, publication in a peer-reviewed journal is associated with improvement in quality of reporting. They also show that quality of reporting in preprints in the life sciences is within a similar range as that of peer-reviewed articles, albeit slightly lower on average, supporting the idea that preprints should be considered valid scientific contributions. (shrink)

Theory and Practice of Knowledge Transfer: Studies in School Education in the Ancient Near East and Beyond. Edited by W. S. van Egmond and W. H. van Soldt. Publications de l’Institut histo- rique-archéologique néerlandais de Stamboul, vol. 121. Leiden: Nederlands Instituut voor het NabiJe Oosten, 2012. Pp. 111 + 152. €36.04.

A Egmond, le 16 avril 1648, un peu moins de deux ans avant sa mort, Descartes s'entretient avec un étudiant hollandais en théologie, Frans Burman. Le jeune homme de vingt ans présente au philosophe de courts extraits de ses principales oeuvres publiées (Méditations métaphysiques, Principes de la philosophie, Discours de la méthode) que l'auteur en personne se charge d'expliquer, répondant aussi aux objections de son interlocuteur. Ce texte possède donc un statut décisif dans le corpus cartésien car il s'agit (...) d'un commentaire des points les plus délicats de la philosophie de Descartes par lui-même. Ce faisant, il ne se contente pas de répéter ce qu'il a déjà écrit sur le doute, la connaissance sensible, l'existence de Dieu, le mouvement de la matière ou encore la santé du corps, il ne cesse au contraire d'approfondir, de nuancer, voire de transformer les thèses sur lesquelles il est interrogé. Ce texte interdit ainsi de faire de la pensée de Descartes une "doctrine" stable et immuable. Il donne plutôt à voir de manière éclatante une pensée en marche, celle d'un philosophe majeur et reconnu qui accepte pourtant de remettre sur la table de travail les points essentiels d'une oeuvre déjà constituée en fonction des questions précises qui lui sont posées. Bien plus qu'un simple résumé de sa philosophie, cet Entretien montre l'inlassable exigence de l'effort de la pensée cartésienne à la conquête de sa propre clarté. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:GOD, EMOTION, AND CORPOREALITY: A THOMIST PERSPECTIVE 1 MARCEL SAROT University of Utrecht Utrecht, The Netherlands I. Introduction WHEN WE TAKE" impassibility" to mean" immutbility with regard to one's feelings or the quality of ne's inner life," 2 the number of adherents to the doctrine of divine impassibility has continuously decreased during the present century. Slowly but surely the concept of an immutable and impassible God has given way (...) to the concept of a sensitive, emotional, passionate God. Before the Second World War this tendency was restricted to British theology,3 but since then it has spread to the rest of Europe, notably to France and Ger1 A first draft of this paper was presented at a meeting of the Aquinas Research Group of the Catholic Theological University of Utrecht (The Netherlands ) in May, 1990. I would like to thank the other participants for their useful comments. The paper also profited from the valuable comments of Prof. Dr. Vincent Brummer and Dr. Christoph Schwi:ibel. The writing of this paper forms part of a research project on divine passibility, supported by the Dutch Research Foundation for Theology and Religious Studies (STEGON), and funded by the Netherlands Organization for the Advancement of Research (NWO). 2 I have argued for this definition in my article " Patripassianism, Theopaschitism and the Suffering of God: Some Historical and Systematic Considerations," Religious Studies 26 (1990) : 363-375. a See A. van Egmond, De Lijdende God in de Britse Theologie van de Negentiende Eeuw: De Bijdrage van Newman, Maurice, McLeod Campbell en Gore aan de Christelijke Theopaschitische Traditie (Amsterdam: VU Uitgeverij, 1986); J. Kenneth Mozley, The Impassibility of God: A Survey of Christian Thought (Cambridge: Cambridge University Press, 1926), pp. 127-166; Doctrine in the Church of England: The Report of the Commission o·n Christian Doctrine Appointed by the Archbishops of Canterbury and York in 1922 (London: SPCK, 1938), pp. 55-56. 61 62 MARCEL SAROT many, to the United States and to Asia.4 By now most of the theologians who explicitly state their views on divine impassibility hold that this doctrine is to a greater or lesser degree false, and Ronald Goetz rightly asserts "that the rejection of the ancient doctrine of divine impassibility has become a theological commonplace." 5 Nevertheless the debate on this issue is not yet closed. Recently Richard Creel published a thorough study in defense of divine impassibility,6 which, I expect, will prove quite influential. Other theologians who defend the doctrine can be cited as well.7 To a large extent, the arguments which these theologians put forward in favor of divine impassibility are taken from the classic Christian theological texts. Among these, the writings of Aquinas are not the least important and no one will be surprised to hear that he is frequently cited in this connection. However, what has surprised me in my study of the debate on the issue of divine impassibility is that one of the most important arguments Aquinas 4 On passibilist tendencies in modern theology, see Richard Bauckham, " ' Only the Suffering God Can Help ' : Divine Passibility in Modern Theology," Themelios 9 (1984) : 6-12; Warren McWilliams, The Passio1i of God: Divine Swffering in Contemporary Protestant Theology (Macon: Mercer University Press, 1985); Van Egmond, De Lijdende God, pp. 28-31, and "Theopaschitische Tendenzen in de Na-Oorlogse Protestantse Theologie," Gereformeerd Theologisch Tijdschrift 79 (1979): 161-177; Marcel Sarot, "De Passibilitas Dei in de Hedendaagse Westerse Theologie: Een Literatuuroverzicht," Kerk en Theologie 40-3 (1989) : 196-206. 5 Ronald Goetz, "The Suffering God: The Rise of a New Orthodoxy," The Christian Century 103 (1986): 385. Also see the literature cited in the preceding note. 6 Richard E. Creel, Divine Impassibility: An Essay in Philosophical Theology (Cambridge: Cambridge University Press, 1986). 7 See, for instance, Brian Davies, Thinking about God (London: Chapman, 1985), pp. 155-158; William J. Hill, "Does Divine Love Entail Suffering in God?," in: B. L. Clarke & E. T. Long, eds., God and Temporality (New York: Paragon House, 1984), pp. 55-71 ; id., " The Doctrine of God after Vatican II," The Thomist 51 (1987); pp. 412-414; Herbert McCabe, "The Involvement of God," New Blackfriars 66 (1985) : 464-476, reprinted in Herbert McCabe... (shrink)