The Logic of Human Personality shows how the ancient definition of person remains useful today, and explains how it happened to fall into disuse. The method of using the categories of Aristotle is illustrated by showing how action, relation, and time as well as the fundamental category of substance, can help us understand what it is to be a person. The Logic of Human Personality agrues, against Mill and others who have found Aristotle's categories unsatisfactory, that in fact they are (...) useful for much psychological and anthropological research today, particularly in the intercultural field. (shrink)

Some time ago, the philosopher Luciano Floridi suggested that Western philosophy, and the mainstream contemporary approach to it traditionally called ‘analytic philosophy’, is in dire need of a reboot. The concern was that the discipline might be in a period of decadence. Analytic philosophy would be benefited by greater internationalization, wider and more transparent decision-making, and the reduction (as much as possible) of conflicts of interest as well as of its current habit of hiring and providing publication opportunities on the (...) basis of contacts, networking, and academic pedigree. If we are right, then we need a reconditioning of the institutional framework of analytic philosophy that adjusts it to the current global and interconnected world. (shrink)

Variations in levels of apolipoprotein E have been tied to the risk and progression of Alzheimer's disease . Our group has previously compared and contrasted the promoters of the mouse and human ApoE gene promoter sequences and found notable similarities and significant differences that suggest the importance of the APOE promoter's role in the human disease. We examine here three specific single-nucleotide polymorphisms within the human APOE promoter region, specifically at -491 , -427 , and at -219 upstream from the (...) +1 transcription start site. The -219 and -491 polymorphic variations have significant association with instance of AD, and -491AA has significant risk even when stratified for the APOEepsilon4 allele. We also show significant effects on reporter gene expression in neuronal cell cultures, and, notably, these effects are modified by species origin of the cells. The -491 and -219 polymorphisms may have an interactive effect in addition to any independent activity. DNA-protein interactions differ between each polymorphic state. We propose SP1 and GATA as candidates for regulatory control of the -491 and -219 polymorphic sites. This work's significance lies in drawing connection among APOE promoter polymorphisms' associations with AD to functional promoter activity differences and specific changes in DNA-protein interactions in cell culture-based assays. Taken together, these results suggest that APOE expression levels are a risk factor for AD irrespective of APOEepsilon4 allele status. (shrink)

Aristotle maintains that every man has, or should have, a single end, a target at which he aims. The doctrine is stated in E.N. I 2. ‘If, then, there is some end of the things we do which we desire for its own sake, and if we do not choose everything for the sake of something else, clearly this must be the good and the chief good. Will not the knowledge of it, then, have a great influence on life? Shall (...) we not, like archers who have a mark to aim t, be more likely to hit upon what is right?’. Aristotle does not here prove, nor need we understand him as claiming to prove, that there is only one end which is desired for itself. He points out correctly that, if there are objects which are desired but not desired for themselves, there must be some object which is desired for itself. The passage further suggests that, if there were one such object and one only, this fact would be important and helpful for the conduct of life. (shrink)

This is a study of Aristotle's moral philosophy as it is contained in the Nicomachean Ethics. Hardie examines the difficulties of the text; presents a map of inescapable philosophical questions; and brings out the ambiguities and critical disagreements on some central topics, inclduing happiness, the soul, the ethical mean, and the initiation of action.

W. F. R. Hardie; X—Aristotle's Doctrine that Virtue is a “Mean”, Proceedings of the Aristotelian Society, Volume 65, Issue 1, 1 June 1965, Pages 183–204, https.

The words “free will” have uses in ordinary talk as in “free will offering” and, most commonly, in the expression “of my own free will.” We all know what states of affairs make this expression applicable, and its standard use is defined by this application. Yet philosophers discuss, or used to discuss, whether the will is free, libertarians saying that it is and determinists denying this. Are they, or were they, asking whether anyone ever acts of his own free will? (...) If so, the question asked was absurd. (shrink)

Im Mittelpunkt dieser Festschrift für Professorin Joanna Jabłkowska stehen Fragen, die im Zusammenhang mit dem kulturwissenschaftlichen ethical turn in der rezenten literaturwissenschaftlichen Forschung diskutiert werden. Der Zusammenhang zwischen Ethik und Literatur wird sowohl theoretisch erfasst als auch in zahlreichen Einzelanalysen literarischer Werke diskutiert. Die literaturwissenschaftliche Perspektive wird ergänzt durch philosophische und politische Betrachtungsweisen.

Does Aristotle in the Nicomachean Ethics give one consistent answer to the question what life is best or two mutually inconsistent answers? In the First Book he says that we can agree to say that the best life is eudaimonia or eupraxia but must go on to say in what eudaimonia consists. By considering the specific nature of man as a thinking animal he reaches a conclusion: eudaimonia, the human good, is the activity of soul in accordance with virtue, and (...) if there are more than one virtue in accordance with the best and most complete, and in a complete life. Aristotle states that his formula is no more than a sketch or outline, but that a good sketch is important since, if the outline is right, anyone can articulate it and supply details. He seems to be thinking here not just of the rest of his own treatise but of the work of pupils and successors; he speaks, as at the end of the Topics, of progress in a science. (shrink)

John Conington was a towering figure in Victorian scholarship, not least because of his remarkably sensitive and literate commentaries on Virgil’s _Aeneid. _The three-volume cloth edition of _The Works of Virgil_, begun by Conington in 1852, has been unavailable for over a century, except in rare second-hand sets. Now, for the first time, the whole of Conington’s work is being reissued in a set of six paperback volumes. Each volume includes a new introduction by an established scholar, setting Conington's commentary (...) in context, as well as a general introduction to Conington’s work by Philip Hardie, who offers a fresh appreciation of the work. (shrink)

A decade on after it first published to international acclaim, the seminal Handbook of Organization Studies has been updated to capture exciting new developments in the field. Providing a retrospective and prospective overview of organization studies, this Handbook continues to challenge and inspire readers with its synthesis of knowledge and literature. As ever, contributions have been selected to reflect the diversity of the field. New chapters cover areas such as organizational change, knowledge management and organizational networks.